| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allison M Heskes, Tamil C M Sundram, Berin A Boughton, Niels B Jensen, Nikolaj L Hansen, Christoph Crocoll, Federico Cozzi, Simon Rasmussen, Britta Hamberger, Björn Hamberger, Dan Staerk, Birger L Møller, Irini Paterak. Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus-castus. The Plant journal : for cell and molecular biology. vol 93. issue 5. 2019-01-14. PMID:29315936. |
this feature has been attributed to the presence of dopaminergic diterpenoids that can bind to dopamine receptors in the pituitary gland. |
2019-01-14 |
2023-08-13 |
Not clear |
| Elisabeth Zieger, Thurston C Lacalli, Mario Pestarino, Michael Schubert, Simona Candian. The origin of dopaminergic systems in chordate brains: insights from amphioxus. The International journal of developmental biology. vol 61. issue 10-11-12. 2019-01-10. PMID:29319121. |
the th+ cells probably contain either l-dopa or dopamine, and correspond closely with a cell population known from previous work on adult amphioxus to be dopaminergic. |
2019-01-10 |
2023-08-13 |
Not clear |
| Mostafa A Rabie, Mai A Abd El Fattah, Noha N Nassar, Hanan S El-Abhar, Dalaal M Abdalla. Angiotensin 1-7 ameliorates 6-hydroxydopamine lesions in hemiparkinsonian rats through activation of MAS receptor/PI3K/Akt/BDNF pathway and inhibition of angiotensin II type-1 receptor/NF-κB axis. Biochemical pharmacology. vol 151. 2019-01-09. PMID:29428223. |
moreover, ang1-7 increased substantia nigral tyrosine hydroxylase (th) expression and striatal dopamine (da) content to indicate the preservation of the dopaminergic neuronal signal. |
2019-01-09 |
2023-08-13 |
rat |
| Kenji Morita, Ayaka Kat. A Neural Circuit Mechanism for the Involvements of Dopamine in Effort-Related Choices: Decay of Learned Values, Secondary Effects of Depletion, and Calculation of Temporal Difference Error. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29468191. |
here we show that findings i-iii can be explained by the dopaminergic representation of temporal-difference reward-prediction error (td-rpe), whose mechanisms have now become clarified, if (1) the synaptic strengths storing the values of actions mildly decay in time and (2) the obtained-reward-representing excitatory input to dopamine neurons increases after dopamine depletion. |
2019-01-09 |
2023-08-13 |
Not clear |
| Jérôme Linden, Alexander S James, Colin McDaniel, J David Jentsc. Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29527566. |
dopamine d2 receptors in dopaminergic neurons modulate performance in a reversal learning task in mice. |
2019-01-09 |
2023-08-13 |
mouse |
| Marek Gryz, Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Adam Płaźni. Dopaminergic system activity under stress condition - seeking individual differences, preclinical studies. Psychiatria polska. vol 52. issue 3. 2019-01-07. PMID:30218562. |
one of the reason is dysregulation of the dopaminergic system and dysfunction of local dopamine release in the nucleus accumbens. |
2019-01-07 |
2023-08-13 |
Not clear |
| Anastasiia Bohush, Grazyna Niewiadomska, Anna Filipe. Role of Mitogen Activated Protein Kinase Signaling in Parkinson's Disease. International journal of molecular sciences. vol 19. issue 10. 2019-01-07. PMID:30274251. |
parkinson's disease (pd) is a neurodegenerative disorder caused by insufficient dopamine production due to the loss of 50% to 70% of dopaminergic neurons. |
2019-01-07 |
2023-08-13 |
Not clear |
| Anastasiia Bohush, Grazyna Niewiadomska, Anna Filipe. Role of Mitogen Activated Protein Kinase Signaling in Parkinson's Disease. International journal of molecular sciences. vol 19. issue 10. 2019-01-07. PMID:30274251. |
a shortage of dopamine, which is predominantly produced by the dopaminergic neurons within the substantia nigra, causes clinical symptoms such as reduction of muscle mass, impaired body balance, akinesia, bradykinesia, tremors, postural instability, etc. |
2019-01-07 |
2023-08-13 |
Not clear |
| Cihan Kaya, Mary H Cheng, Ethan R Block, Tom M Bartol, Terrence J Sejnowski, Alexander Sorkin, James R Faeder, Ivet Baha. Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency. eNeuro. vol 5. issue 1. 2019-01-02. PMID:29430519. |
efficient clearance of dopamine (da) from the synapse is key to regulating dopaminergic signaling. |
2019-01-02 |
2023-08-13 |
Not clear |
| Federica Bono, Paola Savoia, Adele Guglielmi, Massimo Gennarelli, Giovanna Piovani, Sandra Sigala, Damiana Leo, Stefano Espinoza, Raul R Gainetdinov, Paola Devoto, PierFranco Spano, Cristina Missale, Chiara Fiorentin. Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092083. |
role of dopamine d2/d3 receptors in development, plasticity, and neuroprotection in human ipsc-derived midbrain dopaminergic neurons. |
2019-01-01 |
2023-08-13 |
human |
| Federica Bono, Paola Savoia, Adele Guglielmi, Massimo Gennarelli, Giovanna Piovani, Sandra Sigala, Damiana Leo, Stefano Espinoza, Raul R Gainetdinov, Paola Devoto, PierFranco Spano, Cristina Missale, Chiara Fiorentin. Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092083. |
the role of dopamine d2 and d3 receptors (d2r/d3r), located on midbrain dopaminergic (da) neurons, in the regulation of da synthesis and release and in da neuron homeostasis has been extensively investigated in rodent animal models. |
2019-01-01 |
2023-08-13 |
human |
| Amit Kumar Chauhan, Namrata Mittra, Devendra Kumar Patel, Chetna Sing. Cyclooxygenase-2 Directs Microglial Activation-Mediated Inflammation and Oxidative Stress Leading to Intrinsic Apoptosis in Zn-Induced Parkinsonism. Molecular neurobiology. vol 55. issue 3. 2018-12-31. PMID:28290146. |
zn reduced the neurobehavioral activities, striatal dopamine content, tyrosine hydroxylase (th) expression and number of dopaminergic neurons. |
2018-12-31 |
2023-08-13 |
rat |
| Viet-Duc Phung, Won-Sik Jung, Thuy-An Nguyen, Jong-Hoon Kim, Sang-Wha Le. Reliable and quantitative SERS detection of dopamine levels in human blood plasma using a plasmonic Au/Ag nanocluster substrate. Nanoscale. vol 10. issue 47. 2018-12-19. PMID:30480292. |
accurate and rapid blood-based detection of dopamine levels can aid in the diagnosis and monitoring of diseases related to dopaminergic dysfunction. |
2018-12-19 |
2023-08-13 |
human |
| Sorabh Sharma, Rajeev Taliya. High fat diet feeding induced insulin resistance exacerbates 6-OHDA mediated neurotoxicity and behavioral abnormalities in rats. Behavioural brain research. vol 351. 2018-12-18. PMID:29842916. |
interestingly, we found that exposure to hfd exacerbated the effects of 6-ohda on striatal dopamine loss and behavioral parameters in rats, indicating that hfd-induced insulin resistance is associated with a diminished capacity of dopaminergic neurons to cope with 6-ohda mediated neurotoxicity. |
2018-12-18 |
2023-08-13 |
rat |
| Heng Dai, Chad R Jackson, Gwynne L Davis, Randy D Blakely, Douglas G McMaho. Is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel dopamine transporter variant Val559 transgenic mouse model. Journal of neurodevelopmental disorders. vol 9. issue 1. 2018-12-17. PMID:29281965. |
is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? |
2018-12-17 |
2023-08-13 |
mouse |
| Liana Basova, Julia A Najera, Nikki Bortell, Di Wang, Rosita Moya, Alexander Lindsey, Svetlana Semenova, Ronald J Ellis, Maria Cecilia Garibaldi Marconde. Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection. PloS one. vol 13. issue 6. 2018-12-17. PMID:29944719. |
however, we found that the main factor that modifies the ccr5 gene promoter at the epigenetic level towards transcription is dopamine (da), a neurotransmitter that is produced primarily in brain regions that are rich in dopaminergic neurons. |
2018-12-17 |
2023-08-13 |
human |
| Muhammad Saad Khan, Isabelle Boileau, Nathan Kolla, Romina Mizrah. A systematic review of the role of the nociceptin receptor system in stress, cognition, and reward: relevance to schizophrenia. Translational psychiatry. vol 8. issue 1. 2018-12-12. PMID:29391391. |
first, aberrant glutamatergic and striatal dopaminergic function are associated with psychotic symptoms, and the nociceptin receptor system has been shown to regulate dopamine and glutamate transmission. |
2018-12-12 |
2023-08-13 |
Not clear |
| Jun Zhu, Subramaniam Ananthan, Chang-Guo Zha. The role of human dopamine transporter in NeuroAIDS. Pharmacology & therapeutics. vol 183. 2018-12-11. PMID:28987321. |
the presynaptic dopamine (da) transporter (dat) is essential for da homeostasis and dopaminergic modulation of the brain function including cognition. |
2018-12-11 |
2023-08-13 |
human |
| Agnieszka Wąsik, Irena Romańska, Agnieszka Zelek-Molik, Lucyna Antkiewicz-Michalu. Multiple Administration of Endogenous Amines TIQ and 1MeTIQ Protects Against a 6-OHDA-Induced Essential Fall of Dopamine Release in the Rat Striatum: In Vivo Microdialysis Study. Neurotoxicity research. vol 33. issue 3. 2018-12-11. PMID:29076060. |
the results obtained from the in vivo microdialysis study suggest that multiple treatment with both endogenous amines, tiq and 1metiq, protects dopaminergic neurons against a 6-ohda-induced deficit of dopamine release. |
2018-12-11 |
2023-08-13 |
rat |
| Li Li, Yun-Xiao Kang, Xiao-Ming Ji, Ying-Kun Li, Shuang-Cheng Li, Xiang-Jian Zhang, Hui-Xian Cui, Ge-Ming Sh. Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats. CNS neuroscience & therapeutics. vol 24. issue 2. 2018-12-11. PMID:29214729. |
the present study therefore investigates the effects of finasteride in adolescent and early developmental rats on dopaminergic system, including contents of dopamine and its metabolites (dihydroxy phenyl acetic acid and homovanillic acid) and tyrosine hydroxylase expressions both at gene and protein levels. |
2018-12-11 |
2023-08-13 |
rat |