| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marla Rivera-Oliver, Estefanía Moreno, Yocasta Álvarez-Bagnarol, Christian Ayala-Santiago, Nicole Cruz-Reyes, Gian Carlo Molina-Castro, Stefan Clemens, Enric I Canela, Sergi Ferré, Vicent Casadó, Manuel Díaz-Río. Adenosine A Molecular neurobiology. vol 56. issue 2. 2019-07-11. PMID:29797183. |
adenosine plays a key role in the inhibitory control of the ascending dopaminergic system, largely dependent on functional complexes of specific subtypes of adenosine and dopamine receptors. |
2019-07-11 |
2023-08-13 |
mouse |
| Patricia Di Ciano, Rachel F Tyndale, Esmaeil Mansouri, Christian S Hendershot, Alan A Wilson, Dina Lagzdins, Sylvain Houle, Isabelle Boileau, Bernard Le Fol. Influence of Nicotine Metabolism Ratio on [11C]-(+)-PHNO PET Binding in Tobacco Smokers. The international journal of neuropsychopharmacology. vol 21. issue 6. 2019-07-08. PMID:29346545. |
as reinforcing/rewarding effects of tobacco are associated with dopamine transmission, the purpose of the present study was to study the dopaminergic system in human smokers based on their nicotine metabolite ratio. |
2019-07-08 |
2023-08-13 |
human |
| Mark S Moehle, Tristano Pancani, Nellie Byun, Samantha E Yohn, George H Wilson, Johnathan W Dickerson, Daniel H Remke, Zixiu Xiang, Colleen M Niswender, Jürgen Wess, Carrie K Jones, Craig W Lindsley, Jerri M Rook, P Jeffrey Con. Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M Neuron. vol 96. issue 6. 2019-07-05. PMID:29268098. |
cholinergic projections to the substantia nigra pars reticulata inhibit dopamine modulation of basal ganglia through the m cholinergic regulation of dopaminergic inputs into the striatum is critical for normal basal ganglia (bg) function. |
2019-07-05 |
2023-08-13 |
Not clear |
| Thomas R Barber, Ludovica Griffanti, Kinan Muhammed, Daniel S Drew, Kevin M Bradley, Daniel R McGowan, Marie Crabbe, Christine Lo, Clare E Mackay, Masud Husain, Michele T Hu, Johannes C Klei. Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. Brain : a journal of neurology. vol 141. issue 10. 2019-07-05. PMID:30212839. |
the integrity of the raphe serotonergic system can be assessed alongside dopaminergic basal ganglia imaging using the radioligand 123i-ioflupane, which binds both serotonin and dopamine transporters. |
2019-07-05 |
2023-08-13 |
Not clear |
| Phelippe do Carmo-Gonçalves, Eduardo Coelho-Cerqueira, Juliana R Cortines, Theo Luiz Ferraz de Souza, Luciana Romão, Cristian Follme. In vitro neurotoxicity of salsolinol is attenuated by the presynaptic protein α-synuclein. Biochimica et biophysica acta. General subjects. vol 1862. issue 12. 2019-07-01. PMID:30251672. |
salsolinol (salso), a product from the reaction of dopamine (da) with acetaldehyde, is found increased in dopaminergic neurons of parkinson's disease (pd) patients. |
2019-07-01 |
2023-08-13 |
rat |
| Verônica Tironi Dias, Higor Zuquetto Rosa, Lívia Ferraz D'avila, Luciana Taschetto Vey, Raquel Cristine Silva Barcelos, Marilise Escobar Burge. Modafinil reduces amphetamine preference and prevents anxiety-like symptoms during drug withdrawal in young rats: Involvement of dopaminergic targets in VTA and striatum. Progress in neuro-psychopharmacology & biological psychiatry. vol 92. 2019-06-27. PMID:30664970. |
so far, during the adolescence, md presented beneficial behavioral outcomes that could be attributed to its modulatory activity on the striatal dopaminergic system in an attempt to maintain the adequate dopamine levels. |
2019-06-27 |
2023-08-13 |
rat |
| Jong Hoon Won, Seok Kyun Kim, In Chul Shin, Hae Chan Ha, Ji Min Jang, Moon Jung Back, Dae Kyong Ki. Dopamine transporter trafficking is regulated by neutral sphingomyelinase 2/ceramide kinase. Cellular signalling. vol 44. 2019-06-26. PMID:29329781. |
dopamine (da) reuptake is the primary mechanism to terminate dopaminergic transmission in the synaptic cleft. |
2019-06-26 |
2023-08-13 |
mouse |
| Jens Baron, Ainhoa Bilbao, Heide Hörtnagl, Lutz Birnbaumer, Sarah Leixner, Rainer Spanagel, Gudrun Ahnert-Hilger, Irene Brun. Balance of Go1α and Go2α expression regulates motor function via the striatal dopaminergic system. Journal of neurochemistry. vol 146. issue 4. 2019-06-26. PMID:29747224. |
analysis of dopamine concentration and expression of d1 and d2 receptors unravelled splice-variant-specific imbalances in the striatal dopaminergic system: in go1α-/- mice dopamine concentration and vesicular monoamine uptake were increased compared to wild types. |
2019-06-26 |
2023-08-13 |
mouse |
| Kristel Klaus, Kevin Butler, Ffion Curtis, Chris Bridle, Kyla Penningto. The effect of ANKK1 Taq1A and DRD2 C957T polymorphisms on executive function: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 100. 2019-06-26. PMID:30836122. |
research in healthy adults suggests that c957t polymorphism of the dopamine d2 receptor encoding drd2 and the taq1a polymorphism of the neighbouring gene ankyrin repeat and kinase domain containing 1 (ankk1) alter dopaminergic signalling and may influence prefrontally-mediated executive functions. |
2019-06-26 |
2023-08-13 |
Not clear |
| Patrícia C R Rabelo, Nayara A C Horta, Letícia M S Cordeiro, Maristela O Poletini, Cândido C Coimbra, Raphael E Szawka, Danusa D Soare. Intrinsic exercise capacity in rats influences dopamine neuroplasticity induced by physical training. Journal of applied physiology (Bethesda, Md. : 1985). vol 123. issue 6. 2019-06-20. PMID:28883047. |
to evaluate the dopaminergic neuroplasticity, we analyzed mrna levels of d1 receptor, d2 receptor, dopamine transporter, tyrosine hydroxylase, glia cell line neurotrophic factor, and brain-derived neurotrophic factor as well as concentrations of dopamine, serotonin, and their metabolites. |
2019-06-20 |
2023-08-13 |
rat |
| Kazuhito Nakao, Vivek Jeevakumar, Sunny Zhihong Jiang, Yuko Fujita, Noelia B Diaz, Carlos A Pretell Annan, Karen L Eskow Jaunarajs, Kenji Hashimoto, Juan E Belforte, Kazu Nakazaw. Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29394409. |
interestingly, the magnitude and distribution of amphetamine-induced c-fos expression in dopamine neurons was comparable between genotypes across dopaminergic input subregions in the ventral tegmental area (vta). |
2019-06-19 |
2023-08-13 |
mouse |
| Marcel M Daad. Differentiation of Neural Stem Cells Derived from Induced Pluripotent Stem Cells into Dopaminergic Neurons. Methods in molecular biology (Clifton, N.J.). vol 1919. 2019-06-14. PMID:30656623. |
dopaminergic (da) neurons are involved in many critical functions within the central nervous system (cns), and dopamine neurotransmission impairment underlies a wide range of disorders from motor control deficiencies, such as parkinson's disease (pd), to psychiatric disorders, such as alcoholism, drug addictions, bipolar disorders, schizophrenia and depression. |
2019-06-14 |
2023-08-13 |
Not clear |
| Hyenjong Hong, Marcel M Daad. Generating Neural Stem Cells from iPSCs with Dopaminergic Neurons Reporter Gene. Methods in molecular biology (Clifton, N.J.). vol 1919. 2019-06-14. PMID:30656625. |
tyrosine hydroxylase (th) is the rate-limiting enzyme for the biosynthesis of the dopamine neurotransmitter, and thus it has been used as a reliable marker for dopaminergic neurons in vitro and in vivo. |
2019-06-14 |
2023-08-13 |
Not clear |
| Xuechai Chen, Xiaotong Zheng, Sakhawat Ali, Minjun Guo, Rugang Zhong, Zixuan Chen, Yongqian Zhang, Hong Qing, Yulin Den. Isolation and Sequencing of Salsolinol Synthase, an Enzyme Catalyzing Salsolinol Biosynthesis. ACS chemical neuroscience. vol 9. issue 6. 2019-06-11. PMID:29602279. |
salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline), a derivate of dopamine, is suspected to be the most probable neurotoxin in the degeneration of dopaminergic neurons. |
2019-06-11 |
2023-08-13 |
rat |
| J M Viveros-Paredes, R E Gonzalez-Castañeda, A Escalante-Castañeda, A R Tejeda-Martínez, F Castañeda-Achutiguí, M E Flores-Sot. Effect of inhibition of fatty acid amide hydrolase on MPTP-induced dopaminergic neuronal damage. Neurologia (Barcelona, Spain). vol 34. issue 3. 2019-06-10. PMID:28104279. |
parkinson's disease (pd) is a neurodegenerative disorder characterised by balance problems, muscle rigidity, and slow movement due to low dopamine levels and loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2019-06-10 |
2023-08-13 |
Not clear |
| Alessandra Perugini, Michele A Bass. Perceptual decisions based on previously learned information are independent of dopaminergic tone. Journal of neurophysiology. vol 119. issue 3. 2019-06-10. PMID:29167328. |
to rule out effects of long-term da treatment and dopaminergic neuronal loss such as occur in pd, we also tested a group of people with dopa-unresponsive focal dystonia, a disease that involves the basal ganglia, like pd, but has motor symptoms that are insensitive to dopamine treatment and is not thought to involve frontal cortical da circuits, unlike pd. |
2019-06-10 |
2023-08-13 |
Not clear |
| Lingling Lu, Huanzhen Jia, Ge Gao, Chunli Duan, Jing Ren, Yi Li, Hui Yan. Pink1 Regulates Tyrosine Hydroxylase Expression and Dopamine Synthesis. Journal of Alzheimer's disease : JAD. vol 63. issue 4. 2019-06-10. PMID:29843233. |
its deficiency was shown to decrease dopamine without significant loss of dopaminergic neurons. |
2019-06-10 |
2023-08-13 |
Not clear |
| José Vicente Lafuente, Catalina Requejo, Luisa Uged. Nanodelivery of therapeutic agents in Parkinson's disease. Progress in brain research. vol 245. 2019-06-05. PMID:30961870. |
parkinson's disease (pd) as a motor disorder is pathologically featured by the loss of dopaminergic neurons of the substantia nigra compacta (snc) and the consequent depletion of dopamine in the striatum. |
2019-06-05 |
2023-08-13 |
Not clear |
| Jean-François De Backer, Stéphanie Monlezun, Bérangère Detraux, Adeline Gazan, Laura Vanopdenbosch, Julian Cheron, Giuseppe Cannazza, Sébastien Valverde, Lídia Cantacorps, Mérie Nassar, Laurent Venance, Olga Valverde, Philippe Faure, Michele Zoli, Olivier De Backer, David Gall, Serge N Schiffmann, Alban de Kerchove d'Exaerd. Deletion of EMBO reports. vol 19. issue 9. 2019-06-04. PMID:30002119. |
further, expression of maged1 in the prefrontal cortex (pfc) and the amygdala, but not in dopaminergic or striatal and other gabaergic neurons, is necessary for cocaine-mediated behavioural sensitization, and its expression in the pfc is also required for cocaine-induced extracellular dopamine (da) release in the nucleus accumbens (nac). |
2019-06-04 |
2023-08-13 |
mouse |
| Hu Zhu, Félix Lussier, Charles Ducrot, Marie-Josée Bourque, Joachim P Spatz, Wenli Cui, Li Yu, Wei Peng, Louis-Éric Trudeau, C Geraldine Bazuin, Jean-Francois Masso. Block Copolymer Brush Layer-Templated Gold Nanoparticles on Nanofibers for Surface-Enhanced Raman Scattering Optophysiology. ACS applied materials & interfaces. vol 11. issue 4. 2019-06-03. PMID:30615826. |
we then show the capability of this nanosensor to detect the corelease of the neurotransmitters dopamine and glutamate from living mouse brain dopaminergic neurons with a sensitivity 1 order of magnitude greater than with aggregated aunps. |
2019-06-03 |
2023-08-13 |
mouse |