| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neeraj Joshi, Sarika Sing. Updates on immunity and inflammation in Parkinson disease pathology. Journal of neuroscience research. vol 96. issue 3. 2019-11-18. PMID:29072332. |
pd pathology is related to depleted dopamine levels, α-synuclein aggregation, and death of nigrostriatal dopaminergic neurons. |
2019-11-18 |
2023-08-13 |
Not clear |
| Bing Hu, Qianqian Shi, Yu Guo, Xiyezi Diao, Heng Guo, Jinsong Zhang, Liang Yu, Hao Dai, Luonan Che. The oscillatory boundary conditions of different frequency bands in Parkinson's disease. Journal of theoretical biology. vol 451. 2019-11-18. PMID:29727632. |
the most important pathological change in pd is the degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain, which results in a decrease in the dopamine (da) content of the striatum. |
2019-11-18 |
2023-08-13 |
Not clear |
| Julieta Acosta, Marcos A Campolongo, Christian Höcht, Amaicha M Depino, Diego A Golombek, Patricia V Agostin. Deficits in temporal processing in mice prenatally exposed to Valproic Acid. The European journal of neuroscience. vol 47. issue 6. 2019-11-12. PMID:28612411. |
furthermore, catecholamine determination by hplc-ed indicated significant differences in striatal dopaminergic, but not serotonergic, content in female and male vpa mice, consistent with previously identified alterations in dopamine metabolism in asd. |
2019-11-12 |
2023-08-13 |
mouse |
| Shaun W Carlson, C Edward Dixo. Lithium Improves Dopamine Neurotransmission and Increases Dopaminergic Protein Abundance in the Striatum after Traumatic Brain Injury. Journal of neurotrauma. vol 35. issue 23. 2019-11-12. PMID:29699444. |
lithium improves dopamine neurotransmission and increases dopaminergic protein abundance in the striatum after traumatic brain injury. |
2019-11-12 |
2023-08-13 |
rat |
| Courtney K Walker, Joy K Roche, Vidushi Sinha, Rosalinda C Robert. Substantia nigra ultrastructural pathology in schizophrenia. Schizophrenia research. vol 197. 2019-11-08. PMID:29274737. |
dopamine is thought to play a role in schizophrenia pathology, yet the substantia nigra (sn), the origin of dopaminergic pathways, has not been studied extensively in schizophrenia. |
2019-11-08 |
2023-08-13 |
human |
| Leslie A Zebrowitz, Jasmine Boshyan, Noreen Ward, Luke Hanlin, Jutta M Wolf, Nouchine Hadjikhan. Dietary dopamine depletion blunts reward network sensitivity to face trustworthiness. Journal of psychopharmacology (Oxford, England). vol 32. issue 9. 2019-11-05. PMID:29620428. |
while this is the first study to demonstrate that dopamine depletion blunts the sensitivity of the neural reward system to social stimuli, namely faces varying in trustworthiness, future research should investigate behavioral measures that may be more responsive to dopaminergic effects than face ratings. |
2019-11-05 |
2023-08-13 |
human |
| Véronique Sgambato, Léon Trembla. Pathophysiology of dyskinesia and behavioral disorders in non-human primates: the role of serotonergic fibers. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 8. 2019-11-04. PMID:29502255. |
a major breakthrough has then been made regarding the hypothesis of the involvement of serotonergic fibers in the conversion of l-dopa to dopamine when dopaminergic neurons are dying and to release it, in an uncontrolled manner, as serotonergic neurons are deprived from the machinery required for buffering dopamine from the synaptic cleft. |
2019-11-04 |
2023-08-13 |
monkey |
| Augusta Pisanu, Laura Boi, Giovanna Mulas, Saturnino Spiga, Sandro Fenu, Anna R Cart. Neuroinflammation in L-DOPA-induced dyskinesia: beyond the immune function. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 8. 2019-11-04. PMID:29541852. |
it is proposed that tnf-α may contribute to the altered neuronal responses occurring in lid by targeting receptor trafficking and function in msns, but also dopamine synthesis in preserved dopaminergic terminals and serotonin metabolism in serotonergic neurons. |
2019-11-04 |
2023-08-13 |
rat |
| Zachary N Ghahramani, Miky Timothy, Joshua Varughese, Joseph A Sisneros, Paul M Forlan. Dopaminergic neurons are preferentially responsive to advertisement calls and co-active with social behavior network nuclei in sneaker male midshipman fish. Brain research. vol 1701. 2019-11-04. PMID:30217439. |
we demonstrate that induction of cfos (an immediate early gene product and proxy for neural activation) in two forebrain dopaminergic nuclei is greater in sneaker males exposed to hums but not grunts compared to ambient noise, suggesting hums preferentially activate these nuclei, further asserting dopamine as an important regulator of social-acoustic behaviors. |
2019-11-04 |
2023-08-13 |
Not clear |
| Kara Montgomery, Caleb Corona, Rebekah Frye, Reid Barnett, Andrew Bailey, Vanessa A Fitsanaki. Transport of a manganese/zinc ethylene-bis-dithiocarbamate fungicide may involve pre-synaptic dopaminergic transporters. Neurotoxicology and teratology. vol 68. 2019-10-25. PMID:29807111. |
on the other hand, pretreatment with a dopamine transporter antagonist (gbr12909) appeared to protect dopaminergic neurons from chronic (24 h) mz treatment. |
2019-10-25 |
2023-08-13 |
caenorhabditis_elegans |
| Da-Seul Kim, Ee-Seul Kang, Seungho Baek, Sung-Sik Choo, Yong-Ho Chung, Donghyun Lee, Junhong Min, Tae-Hyung Ki. Electrochemical detection of dopamine using periodic cylindrical gold nanoelectrode arrays. Scientific reports. vol 8. issue 1. 2019-10-23. PMID:30232374. |
therefore, we concluded that the developed dopamine sensing platform caune can be used for many applications including early diagnosis of neurological diseases; function tests of dopaminergic neurons derived from various stem cell sources; and toxicity assessments of drugs, chemicals, and nanomaterials on human neuronal cells. |
2019-10-23 |
2023-08-13 |
human |
| Nedjeljka Ivica, Ulrike Richter, Joel Sjöbom, Ivani Brys, Martin Tamtè, Per Petersso. Changes in neuronal activity of cortico-basal ganglia-thalamic networks induced by acute dopaminergic manipulations in rats. The European journal of neuroscience. vol 47. issue 3. 2019-10-22. PMID:29250896. |
the basal ganglia are thought to be particularly sensitive to changes in dopaminergic tone, and the realization that reduced dopaminergic signaling causes pronounced motor dysfunction is the rationale behind dopamine replacement therapy in parkinson's disease. |
2019-10-22 |
2023-08-13 |
rat |
| Nedjeljka Ivica, Ulrike Richter, Joel Sjöbom, Ivani Brys, Martin Tamtè, Per Petersso. Changes in neuronal activity of cortico-basal ganglia-thalamic networks induced by acute dopaminergic manipulations in rats. The European journal of neuroscience. vol 47. issue 3. 2019-10-22. PMID:29250896. |
to clarify this, we have here recorded neuronal activity throughout the cortico-basal ganglia-thalamic circuits in freely behaving rats during periods of immobility following acute dopaminergic manipulations, involving both vesicular dopamine depletion and antagonism of d1 and d2 type dopamine receptors. |
2019-10-22 |
2023-08-13 |
rat |
| Natalie A Pride, Belinda Barton, Paul Hutchins, David R Coghill, Mayuresh S Korgaonkar, Stephen J C Hearps, Melissa Rouel, Stephanie Malarbi, Kathryn N North, Jonathan M Payn. Effects of methylphenidate on cognition and behaviour in children with neurofibromatosis type 1: a study protocol for a randomised placebo-controlled crossover trial. BMJ open. vol 8. issue 8. 2019-10-22. PMID:30166301. |
methylphenidate, a stimulant medication that increases dopaminergic and noradrenergic neurotransmission, rescued the behavioural and dopamine abnormalities. |
2019-10-22 |
2023-08-13 |
mouse |
| Yuen-Siang Ang, Sanjay Manohar, Olivia Plant, Annika Kienast, Campbell Le Heron, Kinan Muhammed, Michele Hu, Masud Husai. Dopamine Modulates Option Generation for Behavior. Current biology : CB. vol 28. issue 10. 2019-10-15. PMID:29731299. |
to assess influence of dopamine, we first examined patients with parkinson's disease (n = 35) on and off their dopaminergic medication and compared them to elderly healthy controls (n = 34). |
2019-10-15 |
2023-08-13 |
human |
| Anindita Bose, Gregory A Petsko, David Elieze. Parkinson's Disease and Melanoma: Co-Occurrence and Mechanisms. Journal of Parkinson's disease. vol 8. issue 3. 2019-10-15. PMID:29991141. |
parkinson's disease (pd) is a neurodegenerative disorder that is characterized by loss of dopaminergic neurons in the substantia nigra pars compacta, depletion of dopamine in the striatum and the presence of lewy bodies. |
2019-10-15 |
2023-08-13 |
Not clear |
| Jin-Zhong Huang, Yi Ren, Yuan Xu, Tao Chen, Terry C Xia, Zhuo-Ri Li, Jian-Nong Zhao, Fei Hua, Shi-Ying Sheng, Ying Xi. The delta-opioid receptor and Parkinson's disease. CNS neuroscience & therapeutics. vol 24. issue 12. 2019-10-14. PMID:30076686. |
although it is known that the major characteristics of pd pathophysiology are the dysfunction of basal ganglia due to injury/loss of dopaminergic neurons in the substantia nigra pars compacta dopaminergic and exhaustion of corpus striatum dopamine, therapeutic modalities for pd are limited in clinical settings up to date. |
2019-10-14 |
2023-08-13 |
Not clear |
| Susan Burks, James Raymick, Bonnie Robinson, Joseph Hanig, Sumit Sarka. Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson's disease mouse model: Endothelial and microglial effects. Neuroscience letters. vol 703. 2019-10-11. PMID:30890473. |
parkinson's disease (pd) is a progressive motor disease with clinical features emerging due to degeneration of dopaminergic neurons in the substantia nigra pars compacta (snc), which project to the caudate putamen (cpu) where they release dopamine (da). |
2019-10-11 |
2023-08-13 |
mouse |
| Nareshwaran Gnanasegaran, Vijayendran Govindasamy, Premasangery Kathirvaloo, Sabri Musa, Noor Hayaty Abu Kasi. Effects of cell cycle phases on the induction of dental pulp stem cells toward dopaminergic-like cells. Journal of tissue engineering and regenerative medicine. vol 12. issue 2. 2019-10-09. PMID:28079995. |
parkinson's disease (pd) is characterized by tremors and cognitive issues, and is due to the death of dopaminergic (da-ergic) neurons in brain circuits that are responsible for producing neurotransmitter dopamine (da). |
2019-10-09 |
2023-08-13 |
Not clear |
| Aude Retailleau, Genela Morri. Spatial Rule Learning and Corresponding CA1 Place Cell Reorientation Depend on Local Dopamine Release. Current biology : CB. vol 28. issue 6. 2019-10-08. PMID:29502949. |
since dopamine is involved in reward processing, affects hippocampal-dependent behavior, and modulates hippocampal plasticity, we hypothesized that local dopaminergic transmission in the hippocampus serves to mold the formation and updating of hippocampal cognitive maps to adaptively represent reward-predicting space of sensory inputs. |
2019-10-08 |
2023-08-13 |
rat |