| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Varrial. Role of dopamine in congestive heart failure: a contemporary appraisal. Congestive heart failure (Greenwich, Conn.). vol 5. issue 3. 2019-11-20. PMID:12189316. |
low dose dopamine (0.5-2 micro g/kg/min) induces intrarenal vasodilatation, augmented renal blood flow, and inhibition of renal tubular sodium reabsorption through direct stimulation of peripheral dopaminergic receptors da1 and da2. |
2019-11-20 |
2023-08-12 |
Not clear |
| Gopakumar P. Panikka. Cocaine Addiction: Neurobiology and Related Current Research in Pharmacotherapy. Substance abuse. vol 20. issue 3. 2019-11-20. PMID:12511828. |
the vicissitudes in the dopamine theory of brain reward mechanisms, dopaminergic effects of cocaine, and emerging roles of gaba, serotonin, glutamate, and nitric oxide in cocaine addiction and its sequelae are discussed. |
2019-11-20 |
2023-08-12 |
Not clear |
| F. Viallet, T. Witja. [Neuroplasticity and Parkinson's disease] Revue neurologique. vol 158. issue 122. 2019-11-20. PMID:12690314. |
after a brief survey of some general aspects of plasticity in the cns, the present tutorial review illustrates with recent data from the literature the modes of plastic changes during the course of ipd, either resulting from dopaminergic denervation (hyperactivity of remaining dopaminergic neurons with increase of their excitatory cholinergic innervation in the substantia nigra, enhancement of the corticostriatal glutamatergic synaptic activity at the striatal level) or due to dopaminergic treatment (change in phosphorylation state of the striatal glutamate receptors, internalization of d1 dopamine receptors). |
2019-11-20 |
2023-08-12 |
Not clear |
| A. Nieoullon, M. Amalri. [Brain dopamine receptors: molecular aspects and functional implications] Revue neurologique. vol 158. issue 122. 2019-11-20. PMID:12690316. |
[brain dopamine receptors: molecular aspects and functional implications] during the last decade, molecular biology methods have primarily contributed to the fine characterisation of five subtypes of dopaminergic receptors leading to the classification of the d1-like (d1 and d5) and d2-like (d2, d3 and d4) subclasses. |
2019-11-20 |
2023-08-12 |
Not clear |
| A. Nieoullon, M. Amalri. [Brain dopamine receptors: molecular aspects and functional implications] Revue neurologique. vol 158. issue 122. 2019-11-20. PMID:12690316. |
in this respect, in parkinson's disease dopamine depletion will favour adaptive responses at the cellular level which likely involve differentially the dopaminergic receptor subtypes. |
2019-11-20 |
2023-08-12 |
Not clear |
| Stefanos Stagkourakis, Hoseok Kim, David J Lyons, Christian Broberge. Dopamine Autoreceptor Regulation of a Hypothalamic Dopaminergic Network. Cell reports. vol 15. issue 4. 2019-11-20. PMID:27149844. |
dopamine autoreceptor regulation of a hypothalamic dopaminergic network. |
2019-11-20 |
2023-08-13 |
rat |
| Jana Drgonova, Donna Walther, G Luke Hartstein, Mohammad O Bukhari, Michael H Baumann, Jonathan Katz, Frank Scott Hall, Elizabeth R Arnold, Shaun Flax, Anthony Riley, Olga Rivero-Martin, Klaus-Peter Lesch, Juan Troncoso, Barbara Ranscht, George R Uh. Cadherin 13: human Molecular medicine (Cambridge, Mass.). vol 22. 2019-11-20. PMID:27579475. |
in assessments of brain changes that might contribute to these behavioral differences, there are selective alterations of dopamine levels, dopamine/metabolite ratios, dopaminergic fiber densities and mrna encoding the activity dependent transcription factor |
2019-11-20 |
2023-08-13 |
mouse |
| Natasa Kustrimovic, Emanuela Rasini, Massimiliano Legnaro, Raffaella Bombelli, Iva Aleksic, Fabio Blandini, Cristoforo Comi, Marco Mauri, Brigida Minafra, Giulio Riboldazzi, Vanesa Sanchez-Guajardo, Franca Marino, Marco Cosentin. Dopaminergic Receptors on CD4+ T Naive and Memory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson's Disease. Scientific reports. vol 6. 2019-11-20. PMID:27652978. |
since the mainstay of pd treatment is dopaminergic substitution therapy and dopamine is an established transmitter connecting nervous and immune systems, we examined cd4+ t naive and memory lymphocytes in pd patients and in healthy subjects (hs), with specific regard to dopaminergic receptor (dr) expression. |
2019-11-20 |
2023-08-13 |
human |
| A Gugliandolo, P Bramanti, E Mazzo. Mesenchymal stem cell therapy in Parkinson's disease animal models. Current research in translational medicine. vol 65. issue 2. 2019-11-20. PMID:28466824. |
parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, and as a consequence, by decreased dopamine levels in the striatum. |
2019-11-20 |
2023-08-13 |
Not clear |
| Roger S K Fung, Bai Jin, Mulan He, Karen W Y Yuen, Anderson O L Won. Grass Carp Follisatin: Molecular Cloning, Functional Characterization, Dopamine D1 Regulation at Pituitary Level, and Implication in Growth Hormone Regulation. Frontiers in endocrinology. vol 8. 2019-11-20. PMID:28883808. |
meanwhile, follistatin mrna levels could be up-regulated by local production of activin but the opposite was true for dopaminergic activation with dopamine (da) or its agonist apomorphine. |
2019-11-20 |
2023-08-13 |
Not clear |
| Mi-Hyun Choi, Ji Eun Na, Ye Ran Yoon, Hyo Jin Lee, Sehyoun Yoon, Im Joo Rhyu, Ja-Hyun Bai. Role of Dopamine D2 Receptor in Stress-Induced Myelin Loss. Scientific reports. vol 7. issue 1. 2019-11-20. PMID:28912499. |
dopaminergic systems play a major role in reward-related behavior and dysregulation of dopamine (da) systems can cause several mental disorders, including depression. |
2019-11-20 |
2023-08-13 |
Not clear |
| Panchanan Maiti, Jayeeta Manna, Gary L Dunba. Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments. Translational neurodegeneration. vol 6. 2019-11-20. PMID:29090092. |
gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize parkinson's disease (pd). |
2019-11-20 |
2023-08-13 |
Not clear |
| Syed F Ali, Yossef Itzha. Effects of 7-Nitroindazole, an NOS Inhibitor on Methamphetamine-Induced Dopaminergic and Serotonergic Neurotoxicity in Mice Annals of the New York Academy of Sciences. vol 844. issue 1. 2019-11-20. PMID:29090810. |
effects of 7-nitroindazole, an nos inhibitor on methamphetamine-induced dopaminergic and serotonergic neurotoxicity in mice methamphetamine (meth) is one of the major drugs of abuse that is postulated to cause neurotoxicity by depleting dopamine (da) and its metabolites, high-affinity da uptake sites, and the activity of tyrosine hydroxylase. |
2019-11-20 |
2023-08-13 |
mouse |
| R Sarojini, R Nagabhushanam, M Fingerma. In Vivo Effects of Dopamine and Dopaminergic Antagonists on Testicular Maturation in the Red Swamp Crayfish, Procambarus clarkii. The Biological bulletin. vol 189. issue 3. 2019-11-20. PMID:29244575. |
in vivo effects of dopamine and dopaminergic antagonists on testicular maturation in the red swamp crayfish, procambarus clarkii. |
2019-11-20 |
2023-08-13 |
Not clear |
| Pablo Garrido-Gil, Antonio Dominguez-Meijide, Rosario Moratalla, Maria J Guerra, Jose L Labandeira-Garci. Aging-related dysregulation in enteric dopamine and angiotensin system interactions: implications for gastrointestinal dysfunction in the elderly. Oncotarget. vol 9. issue 13. 2019-11-20. PMID:29541380. |
we showed a mutual regulation between the colonic dopaminergic system and ras using young and aged mice deficient for major angiotensin and dopamine receptors. |
2019-11-20 |
2023-08-13 |
mouse |
| Agnieszka A Kaczor, Justyna Żuk, Dariusz Matosiu. Comparative molecular field analysis and molecular dynamics studies of the dopamine D Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents. vol 27. issue 4. 2019-11-20. PMID:29576721. |
comparative molecular field analysis and molecular dynamics studies of the dopamine d the dopaminergic hypothesis of schizophrenia is the main concept explaining the direct reasons of schizophrenia and the effectiveness of current antipsychotics. |
2019-11-20 |
2023-08-13 |
Not clear |
| Philip Raskin, Anthony H Cincott. Bromocriptine-QR therapy for the management of type 2 diabetes mellitus: developmental basis and therapeutic profile summary. Expert review of endocrinology & metabolism. vol 11. issue 2. 2019-11-20. PMID:30058874. |
in particular, a diminution of the circadian peak in dopaminergic input to the peri-scn facilitates the onset of fattening, insulin resistance and glucose intolerance while reversal of low circadian peak dopaminergic activity to the peri-scn via direct timed dopamine administration to this area normalizes the obese, insulin resistant, glucose intolerant state in high fat fed animals. |
2019-11-20 |
2023-08-13 |
human |
| Philip Raskin, Anthony H Cincott. Bromocriptine-QR therapy for the management of type 2 diabetes mellitus: developmental basis and therapeutic profile summary. Expert review of endocrinology & metabolism. vol 11. issue 2. 2019-11-20. PMID:30058874. |
systemic circadian-timed daily administration of a potent dopamine d2 receptor agonist, bromocriptine, to increase diminished circadian peak dopaminergic hypothalamic activity across a wide variety of animal models of metabolic syndrome and type 2 diabetes mellitus (t2dm) results in improvements in the obese, insulin resistant, glucose intolerant condition by improving hypothalamic fuel sensing and reducing insulin resistance, elevated sympathetic tone, and leptin resistance. |
2019-11-20 |
2023-08-13 |
human |
| Delphine Charvin, Rossella Medori, Robert A Hauser, Olivier Rasco. Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs. Nature reviews. Drug discovery. vol 17. issue 11. 2019-11-20. PMID:30262889. |
existing therapeutic strategies for managing parkinson disease (pd), which focus on addressing the loss of dopamine and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy. |
2019-11-20 |
2023-08-13 |
Not clear |
| Zade R Holloway, Timothy G Freels, Josiah F Comstock, Hunter G Nolen, Helen J Sable, Deranda B Leste. Comparing phasic dopamine dynamics in the striatum, nucleus accumbens, amygdala, and medial prefrontal cortex. Synapse (New York, N.Y.). 2019-11-20. PMID:30317673. |
to summarize results, the present study found that the striatum and nac had increased stimulation-evoked phasic dopamine release, faster dopamine uptake (leading to restricted dopamine diffusion), weaker autoreceptor functioning, greater supply levels of available dopamine, and increased dopaminergic responses to dat blockade compared to the amygdala and mpfc. |
2019-11-20 |
2023-08-13 |
mouse |