| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Ehara, Y Maegaki, K Takeshit. Neuroleptic malignant syndrome and methylphenidate. Pediatric neurology. vol 19. issue 4. 1999-02-10. PMID:9831002. |
however, methylphenidate is a dopamine agonist via the inhibition of uptake of dopamine, and therefore dopaminergic systems in the brainstem (mainly the midbrain) and the spinal cord were unlikely to participate in the onset of this syndrome. |
1999-02-10 |
2023-08-12 |
Not clear |
| N Hironaka, Y Kohno, T Yanagit. [Comparative studies on antiparkinsonian agents, talipexole and bromocriptine, evaluated by contralateral rotational behavior in unilaterally nigral-lesioned rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 112. issue 4. 1999-02-10. PMID:9866843. |
these results indicated that when the nigrostriatal dopaminergic functions are disrupted, talipexole stimulates the striatal postsynaptic dopamine receptors at much lower doses than bromocriptine. |
1999-02-10 |
2023-08-12 |
rat |
| A M Lin, C Y Cha. Role of dopamine uptake in NMDA-modulated K(+)-evoked dopamine overflow in rat striatum: an in vivo electrochemical study. Neuroscience research. vol 31. issue 3. 1999-02-05. PMID:9809662. |
an involvement of dopamine uptake in the n-methyl-d-aspartate (nmda)-modulated dopaminergic transmission in rat striatum was studied using the technique of in vivo electrochemical detection. |
1999-02-05 |
2023-08-12 |
rat |
| A Ekesbo, E Rydin, R Torstenson, O Sydow, B Låengström, J Tedrof. Dopamine autoreceptor function is lost in advanced Parkinson's disease. Neurology. vol 52. issue 1. 1999-02-04. PMID:9921858. |
regional presynaptic dopaminergic function and its regulation by dopamine agonists in different stages of pd can be measured by l-[11c]dopa and pet. |
1999-02-04 |
2023-08-12 |
Not clear |
| K Zimmermann, B Hengere. Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons. Bioorganic & medicinal chemistry letters. vol 8. issue 3. 1999-02-01. PMID:9871666. |
design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons. |
1999-02-01 |
2023-08-12 |
Not clear |
| M Koc. Sensorimotor gating changes across the estrous cycle in female rats. Physiology & behavior. vol 64. issue 5. 1999-01-29. PMID:9817573. |
because a prominent role for dopamine and serotonin in the regulation of ppi in rats has been shown, and because there is evidence for a strong interaction between estrogen and the monoaminergic systems, the present data are consistent with the hypothesis that estrogen regulates ppi through an interaction with the dopaminergic and/or serotonergic systems. |
1999-01-29 |
2023-08-12 |
rat |
| R R Gainetdinov, W C Wetsel, S R Jones, E D Levin, M Jaber, M G Caro. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). vol 283. issue 5400. 1999-01-28. PMID:9888856. |
mice lacking the gene encoding the plasma membrane dopamine transporter (dat) have elevated dopaminergic tone and are hyperactive. |
1999-01-28 |
2023-08-12 |
mouse |
| A Rinken, U B Finnman, K Fux. Pharmacological characterization of dopamine-stimulated [35S]-guanosine 5'(gamma-thiotriphosphate) ([35S]GTPgammaS) binding in rat striatal membranes. Biochemical pharmacology. vol 57. issue 2. 1999-01-28. PMID:9890563. |
comparison of the obtained data with the dissociation constants of these ligands to different subtypes of dopamine receptors gave a good correlation only with constants for the d2 subtype, supporting the idea that this subtype is most likely responsible for the dopaminergic activation of [35s]gtpgammas binding in rat striatal membranes. |
1999-01-28 |
2023-08-12 |
rat |
| T D Geracioti, S A West, D G Baker, K K Hill, N N Ekhator, M D Wortman, P E Keck, A B Norma. Low CSF concentration of a dopamine metabolite in tobacco smokers. The American journal of psychiatry. vol 156. issue 1. 1999-01-27. PMID:9892309. |
to screen for dopaminergic abnormalities in tobacco smokers and patients with posttraumatic stress disorder (ptsd), the authors determined serial csf and plasma concentrations of the dopamine metabolite homovanillic acid (hva). |
1999-01-27 |
2023-08-12 |
Not clear |
| M S Szczypka, Q Y Zhou, R D Palmite. Dopamine-stimulated sexual behavior is testosterone dependent in mice. Behavioral neuroscience. vol 112. issue 5. 1999-01-26. PMID:9829800. |
mice unable to synthesize dopamine (da) in dopaminergic neurons were generated by gene-targeting techniques (q.-y. |
1999-01-26 |
2023-08-12 |
mouse |
| S Lahlou, G P Duart. Hypotensive action of bromocriptine in the DOCA-salt hypertensive rat: contribution of spinal dopamine receptors. Fundamental & clinical pharmacology. vol 12. issue 6. 1999-01-21. PMID:9917201. |
bromocriptine is mediated partly through a peripheral d2 dopaminergic mechanism and partly through stimulation of spinal dopamine d2 receptors, has been demonstrated in conscious normotensive rats. |
1999-01-21 |
2023-08-12 |
rat |
| K Nishii, N Matsushita, H Sawada, H Sano, Y Noda, T Mamiya, T Nabeshima, I Nagatsu, T Hata, K Kiuchi, H Yoshizato, K Nakashima, T Nagatsu, K Kobayash. Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission. Journal of neuroscience research. vol 54. issue 4. 1999-01-19. PMID:9822156. |
mice lacking expression of tyrosine hydroxylase (th), the first and rate-limiting enzyme of the catecholamine biosynthetic pathway, in dopaminergic neuronal cell types were generated by a transgenic rescue approach to clarify the role of dopamine signaling during postnatal development. |
1999-01-19 |
2023-08-12 |
mouse |
| K Nishii, N Matsushita, H Sawada, H Sano, Y Noda, T Mamiya, T Nabeshima, I Nagatsu, T Hata, K Kiuchi, H Yoshizato, K Nakashima, T Nagatsu, K Kobayash. Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission. Journal of neuroscience research. vol 54. issue 4. 1999-01-19. PMID:9822156. |
lack of th expression in the cells that normally express the dopaminergic phenotype resulted in a marked reduction of dopamine accumulation in the tissues, which led to multiple behavioral abnormalities at the juvenile stage. |
1999-01-19 |
2023-08-12 |
mouse |
| K Nishii, N Matsushita, H Sawada, H Sano, Y Noda, T Mamiya, T Nabeshima, I Nagatsu, T Hata, K Kiuchi, H Yoshizato, K Nakashima, T Nagatsu, K Kobayash. Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission. Journal of neuroscience research. vol 54. issue 4. 1999-01-19. PMID:9822156. |
in contrast, development of the pituitary gland as well as production and secretion of the pituitary peptide hormones dependent on hypothalamic dopaminergic control were normally maintained, despite defective dopamine synthesis. |
1999-01-19 |
2023-08-12 |
mouse |
| H C Dringenberg, M A de Souza-Silva, R K Schwarting, J P Husto. Increased levels of extracellular dopamine in neostriatum and nucleus accumbens after histamine H1 receptor blockade. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 4. 1999-01-14. PMID:9826064. |
the dopaminergic system plays a central role in the processing of reward or reinforcement since drugs that have reinforcing properties all share the ability to elevate dopamine (da) levels in the nucleus accumbens or neostriatum. |
1999-01-14 |
2023-08-12 |
rat |
| M P Martres, B Demeneix, N Hanoun, M Hamon, B Giro. Up- and down-expression of the dopamine transporter by plasmid DNA transfer in the rat brain. The European journal of neuroscience. vol 10. issue 12. 1999-01-14. PMID:9875340. |
the functional role of the dopamine transporter (dat) in central dopaminergic neurotransmission was assessed further by investigating the consequences on dopamine (da) turn-over of up- and down-regulation of this protein induced by a non-viral gene transfer approach. |
1999-01-14 |
2023-08-12 |
rat |
| J Birtwistle, D Baldwi. Role of dopamine in schizophrenia and Parkinson's disease. British journal of nursing (Mark Allen Publishing). vol 7. issue 14. 1999-01-07. PMID:9849144. |
the neurotransmitter dopamine (da) and the dopaminergic neurones play an important role in schizophrenia and parkinson's disease (pd). |
1999-01-07 |
2023-08-12 |
Not clear |
| M Pestana, H Jardim, C Afonso, P Serrão, N Santos, L Guerra, P Soares-da-Silv. Renal dopaminergic system in nephrotic syndrome and after remission. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 13. issue 10. 1999-01-04. PMID:9794559. |
although intrarenal dopamine is known to behave as an endogenous natriuretic hormone the role of the renal dopaminergic system in the sodium handling of nephrotic oedema remains unknown. |
1999-01-04 |
2023-08-12 |
Not clear |
| B F El-Khodor, P Boks. Birth insult increases amphetamine-induced behavioral responses in the adult rat. Neuroscience. vol 87. issue 4. 1998-12-30. PMID:9759977. |
these findings highlight the sensitivity of dopamine pathways to variations in birth procedure and add experimental support to epidemiological evidence implicating birth complications in the pathophysiology of disorders involving central dopaminergic neurons, such as schizophrenia. |
1998-12-30 |
2023-08-12 |
rat |
| L García-Gil, J A Ramos, T Rubino, D Parolaro, J J Fernández-Rui. Perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mRNA levels in midbrain dopaminergic neurons of adult male and female rats. Neurotoxicology and teratology. vol 20. issue 5. 1998-12-17. PMID:9761594. |
perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mrna levels in midbrain dopaminergic neurons of adult male and female rats. |
1998-12-17 |
2023-08-12 |
rat |