| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Ridd, I Kitchen, P Fosbrae. The effect of acute kainic acid treatment on dopamine D2 receptors in rat brain. Neuroscience research. vol 30. issue 3. 1998-12-08. PMID:9593330. |
acute exposure to kainic acid (ka) induces neurochemical changes in dopaminergic systems in the brain and the aim of the present study was to investigate the acute toxicity of ka upon dopamine d2 receptors. |
1998-12-08 |
2023-08-12 |
rat |
| S G Schwab, J Hallmayer, B Lerer, M Albus, M Borrmann, S Hönig, M Strauss, R Segman, D Lichtermann, M Knapp, M Trixler, W Maier, D B Wildenaue. Support for a chromosome 18p locus conferring susceptibility to functional psychoses in families with schizophrenia, by association and linkage analysis. American journal of human genetics. vol 63. issue 4. 1998-12-04. PMID:9758604. |
the action of antipsychotic drugs on dopamine receptors suggests that dopaminergic signal transmission may play a role in the development of schizophrenia. |
1998-12-04 |
2023-08-12 |
Not clear |
| R Iu Il'iuchenok, N I Dubrovina, E K Podgornai. [The mechanisms of the emotiogenic regulation of memory]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 9. 1998-12-04. PMID:9817000. |
the gaba system is shown to enter the mechanism that controls the activity of dopamine system--dopamine release from the terminals of the nigrostriatal and mesolimbic dopaminergic systems is stimulated. |
1998-12-04 |
2023-08-12 |
mouse |
| b' K S Raevski\\xc4\\xa. [Functional role and pharmacological regulation of the dopaminergic system of the brain]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 8. 1998-12-01. PMID:9771125.' |
the problem of autoreceptor regulation of dopaminergic neurotransmission, particularly the processes of dopamine synthesis, release, and metabolism is discussed. |
1998-12-01 |
2023-08-12 |
rat |
| K Pong, R Y Xu, W F Baron, J C Louis, K D Bec. Inhibition of phosphatidylinositol 3-kinase activity blocks cellular differentiation mediated by glial cell line-derived neurotrophic factor in dopaminergic neurons. Journal of neurochemistry. vol 71. issue 5. 1998-11-30. PMID:9798915. |
furthermore, we examined specific biological functions of dopaminergic neurons: dopamine uptake activity and morphological differentiation of tyrosine hydroxylase-immunoreactive neurons. |
1998-11-30 |
2023-08-12 |
Not clear |
| D J Healy, V Haroutunian, P Powchik, M Davidson, K L Davis, S J Watson, J H Meador-Woodruf. AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 4. 1998-11-25. PMID:9718591. |
the dopamine hypothesis of schizophrenia has recently evolved into a model of dysfunctional integration between cortical and subcortical dopaminergic activity. |
1998-11-25 |
2023-08-12 |
Not clear |
| D J Nutt, C J Bell, A L Malizi. Brain mechanisms of social anxiety disorder. The Journal of clinical psychiatry. vol 59 Suppl 17. 1998-11-13. PMID:9811424. |
dopaminergic function and striatal dopamine uptake appear to be reduced in social anxiety disorder. |
1998-11-13 |
2023-08-12 |
human |
| O M Youngren, Y Chaiseha, M E El Halawan. Serotonergic stimulation of avian prolactin secretion requires an intact dopaminergic system. General and comparative endocrinology. vol 112. issue 1. 1998-11-10. PMID:9748404. |
in order to ascertain if prolactin (prl) secretion stimulated by serotonin (5-ht) was mediated by the dopaminergic system, both dopamine (da) and 5-ht were infused into the third ventricle of anesthetized laying turkeys in conjunction with the d1 da receptor antagonist r(+)-sch-23390 hcl or the 5-ht receptor antagonist mianserin hcl. |
1998-11-10 |
2023-08-12 |
Not clear |
| K M Webber, J N Pennefather, G A Head, M van den Buus. Endothelin induces dopamine release from rat striatum via endothelin-B receptors. Neuroscience. vol 86. issue 4. 1998-11-06. PMID:9697124. |
these data provide evidence that endothelin acts on a homogeneous population of endothelin-b receptors within the striatum to cause the release of dopamine and that a significant proportion of these receptors is located on dopaminergic neurons. |
1998-11-06 |
2023-08-12 |
rat |
| T Yamakuni, T Yamamoto, M Hoshino, S Y Song, H Yamamoto, M Kunikata-Sumitomo, A Minegishi, M Kubota, M Ito, S Konish. A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes. The Journal of biological chemistry. vol 273. issue 42. 1998-11-06. PMID:9765218. |
catecholaminergic (dopaminergic, noradrenergic, and adrenergic) transmitter phenotypes require the cooperative actions of four biosynthetic enzymes: tyrosine hydroxylase, aromatic l-amino acid decarboxylase, dopamine beta-hydroxylase, and phenylethanolamine n-methyltransferase. |
1998-11-06 |
2023-08-12 |
rat |
| G Di Giovanni, M Di Mascio, V Di Matteo, E Esposit. Effects of acute and repeated administration of amisulpride, a dopamine D2/D3 receptor antagonist, on the electrical activity of midbrain dopaminergic neurons. The Journal of pharmacology and experimental therapeutics. vol 287. issue 1. 1998-11-05. PMID:9765321. |
effects of acute and repeated administration of amisulpride, a dopamine d2/d3 receptor antagonist, on the electrical activity of midbrain dopaminergic neurons. |
1998-11-05 |
2023-08-12 |
Not clear |
| O Rascol, C Brefel-Courbon, O Bli. [Clinical pharmacology of dyskinesias induced by L-dopa in Parkinsonian patients]. Therapie. vol 53. issue 1. 1998-11-03. PMID:9773099. |
new dopaminergic drugs, either with longer elimination half life or with specificity for subtypes of dopamine receptors may allow these dyskinesias to be managed more efficaciously. |
1998-11-03 |
2023-08-12 |
Not clear |
| A Umino, K Takahashi, T Nishikaw. Characterization of the phencyclidine-induced increase in prefrontal cortical dopamine metabolism in the rat. British journal of pharmacology. vol 124. issue 2. 1998-10-29. PMID:9641556. |
however, an nmda antagonist injected into the cell body area of the mesocortical dopaminergic neurones failed to affect dopamine metabolism in the prefrontal cortex. |
1998-10-29 |
2023-08-12 |
rat |
| A Saiardi, E Borrell. Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice. Molecular endocrinology (Baltimore, Md.). vol 12. issue 8. 1998-10-29. PMID:9717839. |
the dopaminergic receptor involved in this control is the dopamine d2 receptor (d2r). |
1998-10-29 |
2023-08-12 |
mouse |
| A Saiardi, E Borrell. Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice. Molecular endocrinology (Baltimore, Md.). vol 12. issue 8. 1998-10-29. PMID:9717839. |
these results reveal a key role for dopamine in the control of pomc-derived peptides and furthermore indicate an implication of the dopaminergic system in the genesis of cushing's syndrome. |
1998-10-29 |
2023-08-12 |
mouse |
| A Mendlin, F J Martín, B L Jacob. Involvement of dopamine D2 receptors in apomorphine-induced facilitation of forebrain serotonin output. European journal of pharmacology. vol 351. issue 3. 1998-10-29. PMID:9721020. |
5-ht efflux was increased by a moderate dose of apomorphine sufficient for a postsynaptic dopaminergic effect (0.5 mg/kg, s.c.), but not by a lower dose (0.1 mg/kg, s.c.), that acts preferentially on presynaptic dopamine receptors. |
1998-10-29 |
2023-08-12 |
rat |
| W P Spooren, A Vassout, P Waldmeier, C Gentsc. Differences in pre- and post-synaptic sensitivity to apomorphine between saline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57BL/6 mice as reflected in climbing activity. European journal of pharmacology. vol 353. issue 1. 1998-10-29. PMID:9721033. |
these data suggest that mptp-treated mice lack pre-synaptic dopamine receptors and have an increased post-synaptic sensitivity for apomorphine which is in agreement with the fact that mptp selectively affects the dopaminergic nigro-striatal pathway which then results in an up-regulation of post-synaptic receptors. |
1998-10-29 |
2023-08-12 |
mouse |
| P Izurieta-Sánchez, S Sarre, G Ebinger, Y Michott. Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats. European journal of pharmacology. vol 353. issue 1. 1998-10-29. PMID:9721037. |
we confirmed that l-dopa induces an increase in striatal dopamine output which is influenced by the severity of the dopaminergic denervation. |
1998-10-29 |
2023-08-12 |
rat |
| S Kitayama, C Mitsuhata, S Davis, J B Wang, T Sato, K Morita, G R Uhl, T Doh. MPP+ toxicity and plasma membrane dopamine transporter: study using cell lines expressing the wild-type and mutant rat dopamine transporters. Biochimica et biophysica acta. vol 1404. issue 3. 1998-10-29. PMID:9739158. |
the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium (mpp+) causes specific cell death in dopaminergic neurons after accumulation by the dopamine transporter (dat). |
1998-10-29 |
2023-08-12 |
rat |
| J A Court, S Lloyd, N Thomas, M A Piggott, E F Marshall, C M Morris, H Lamb, R H Perry, M Johnson, E K Perr. Dopamine and nicotinic receptor binding and the levels of dopamine and homovanillic acid in human brain related to tobacco use. Neuroscience. vol 87. issue 1. 1998-10-26. PMID:9722142. |
these findings suggest that chronic cigarette smoking is associated with a reduction of the firing of nigrostriatal dopaminergic neurons in the absence of changes in the numbers of dopamine receptors and the dopamine transporter. |
1998-10-26 |
2023-08-12 |
human |