| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Fumagalli, R R Gainetdinov, Y M Wang, K J Valenzano, G W Miller, M G Caro. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 7. 1999-04-13. PMID:10087057. |
although it is commonly accepted that the dopaminergic system and oxidation of dopamine (da) play pivotal roles in the neurotoxicity produced by this phenylethylamine, the primary source of da responsible for this effect has remained elusive. |
1999-04-13 |
2023-08-12 |
mouse |
| F Fumagalli, R R Gainetdinov, Y M Wang, K J Valenzano, G W Miller, M G Caro. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 7. 1999-04-13. PMID:10087057. |
meth-induced dopaminergic neurotoxicity was increased in striatum of vmat2 +/- mice compared with wild-type mice as revealed by a more consistent da and metabolite depletion and a greater decrease in dopamine transporter expression. |
1999-04-13 |
2023-08-12 |
mouse |
| A Siderowf, R Kurla. Monoamine oxidase and catechol-O-methyltransferase inhibitors. The Medical clinics of North America. vol 83. issue 2. 1999-04-13. PMID:10093587. |
inhibition of dopamine metabolism is a valuable adjunct to exogenous dopaminergic replacement. |
1999-04-13 |
2023-08-12 |
Not clear |
| D W Miller, E D Abercrombi. Role of high-affinity dopamine uptake and impulse activity in the appearance of extracellular dopamine in striatum after administration of exogenous L-DOPA: studies in intact and 6-hydroxydopamine-treated rats. Journal of neurochemistry. vol 72. issue 4. 1999-04-13. PMID:10098856. |
the differential behavioral and neurochemical effects of exogenous l-dopa in animals with intact versus dopamine (da)-denervated striata raise questions regarding the role of da terminals in the regulation of dopaminergic neurotransmission after administration of exogenous l-dopa. |
1999-04-13 |
2023-08-12 |
rat |
| G P Reynolds, C F Dalton, C L Tillery, L Mangiarini, S W Davies, G P Bate. Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation. Journal of neurochemistry. vol 72. issue 4. 1999-04-13. PMID:10098889. |
dopamine was decreased in the striatum in older animals, parallelling evidence for diminished dopaminergic activity in hd. |
1999-04-13 |
2023-08-12 |
mouse |
| A Peppe, P Stanzione, M Pierantozzi, R Semprini, A Bassi, A M Santilli, R Formisano, M Piccolino, G Bernard. Does pattern electroretinogram spatial tuning alteration in Parkinson's disease depend on motor disturbances or retinal dopaminergic loss? Electroencephalography and clinical neurophysiology. vol 106. issue 4. 1999-04-07. PMID:9741766. |
in order to show possible pattern electroretinogram (perg) spatial tuning function (stf) alterations due to impaired dopaminergic transmission in humans, we studied a group of parkinson's disease patients before and during treatment with the dopamine precursor, levodopa, and compared their performances with those of an age-matched control group. |
1999-04-07 |
2023-08-12 |
Not clear |
| T L Lee, C T Hsu, S T Yen, C W Lai, J T Chen. Activation of beta3-adrenoceptors by exogenous dopamine to lower glucose uptake into rat adipocytes. Journal of the autonomic nervous system. vol 74. issue 2-3. 1999-04-07. PMID:9915622. |
dopamine induced a concentration-dependent decrease of 2-dg uptake into adipocytes in a manner which was not modified by haloperidol at concentrations sufficient to block dopaminergic receptors. |
1999-04-07 |
2023-08-12 |
rat |
| T L Lee, C T Hsu, S T Yen, C W Lai, J T Chen. Activation of beta3-adrenoceptors by exogenous dopamine to lower glucose uptake into rat adipocytes. Journal of the autonomic nervous system. vol 74. issue 2-3. 1999-04-07. PMID:9915622. |
these results suggest that dopamine can activate beta3-adrenoceptors to lower glucose uptake into rat white adipocytes which lack dopaminergic receptors. |
1999-04-07 |
2023-08-12 |
rat |
| E Bezard, C E Gross, M C Fournier, S Dovero, B Bloch, M Jabe. Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter. Experimental neurology. vol 155. issue 2. 1999-04-07. PMID:10072302. |
mpp+, which is the oxidation product of mptp, is actively transported into presynaptic dopaminergic nerve terminals through the plasma membrane dopamine transporter (dat). |
1999-04-07 |
2023-08-12 |
mouse |
| A S Tigano. [Current concept of schizophrenia: state of the art]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 1. 1999-03-31. PMID:10078055. |
this may lead to activation of dopaminergic brain structures with an increase of dopamine receptors. |
1999-03-31 |
2023-08-12 |
Not clear |
| W Timmerman, F Westerhof, T I van der Wal, B H Westerin. Striatal dopamine-glutamate interactions reflected in substantia nigra reticulata firing. Neuroreport. vol 9. issue 17. 1999-03-24. PMID:9875713. |
to gain insight into the role of striatal dopamine in basal ganglia functioning, dopaminergic drugs alone and in combination with the glutamate receptor agonist kainic acid were infused in the lateral striatum via a microdialysis probe, while single-unit recordings of substantia nigra reticulata neurons were made in chloral hydrate-anaesthetized rats. |
1999-03-24 |
2023-08-12 |
rat |
| P Hantray. Modeling dopamine system dysfunction in experimental animals. Nuclear medicine and biology. vol 25. issue 8. 1999-03-23. PMID:9863556. |
diseases of secondary dopamine dysfunction are chiefly represented by huntington's disease in which dopaminergic transmission is being interrupted by progressive loss of the striatal neurons bearing the postsynaptic d1- and d2-dopamine receptors. |
1999-03-23 |
2023-08-12 |
human |
| G T Ramesh, A L Jadha. Region-specific alterations in tyrosine hydroxylase activity in rats exposed to lead. Molecular and cellular biochemistry. vol 189. issue 1-2. 1999-03-23. PMID:9879649. |
previous studies from our laboratory showed that subchronic exposure to low levels of pb resulted in significant decrease in dopamine (da) content, attenuation of stimulus-induced release of da in the dopaminergic projection area of nucleus accumbens (na), and alterations in tyrosine hydroxylase (th) activity in rat whole brain homogenates. |
1999-03-23 |
2023-08-12 |
rat |
| P Boyer, Y Lecrubier, A Stalla-Bourdillon, O Fleuro. Amisulpride versus amineptine and placebo for the treatment of dysthymia. Neuropsychobiology. vol 39. issue 1. 1999-03-22. PMID:9892856. |
amisulpride, a selective antagonist for d2 and d3 dopamine receptors, acts preferentially on presynaptic receptors increasing dopaminergic transmission at low doses. |
1999-03-22 |
2023-08-12 |
Not clear |
| M Morari, M Marti, S Sbrenna, K Fuxe, C Bianchi, L Bean. Reciprocal dopamine-glutamate modulation of release in the basal ganglia. Neurochemistry international. vol 33. issue 5. 1999-03-18. PMID:9874089. |
therefore, glutamatergic modulation of dopamine release has been reviewed by analyzing the effects of glutamatergic selective receptor agonists and antagonists in the striatum (both motor and limbic portions) and in midbrain dopaminergic areas, as revealed by in vitro (slices, cell cultures, synaptosomes) and in vivo (push-pull, microdialysis and voltammetry techniques) experimental approaches. |
1999-03-18 |
2023-08-12 |
rat |
| M Morari, M Marti, S Sbrenna, K Fuxe, C Bianchi, L Bean. Reciprocal dopamine-glutamate modulation of release in the basal ganglia. Neurochemistry international. vol 33. issue 5. 1999-03-18. PMID:9874089. |
in vitro and in vivo experiments in the striatum and midbrain dopaminergic areas mainly depict dopamine as an inhibitory modulator of glutamate release. |
1999-03-18 |
2023-08-12 |
rat |
| F M Inglis, B Moghadda. Dopaminergic innervation of the amygdala is highly responsive to stress. Journal of neurochemistry. vol 72. issue 3. 1999-03-18. PMID:10037480. |
these results suggest that dopaminergic innervation of the amygdala may be more responsive to stress than that of other dopamine-innervated regions of the limbic system, including the prefrontal cortex, and implicate amygdalar dopamine in normal and pathophysiological processes subserving an organism's response to stress. |
1999-03-18 |
2023-08-12 |
rat |
| M E Pedersen, K L Dorrington, P A Robbin. Effects of dopamine and domperidone on ventilatory sensitivity to hypoxia after 8 h of isocapnic hypoxia. Journal of applied physiology (Bethesda, Md. : 1985). vol 86. issue 1. 1999-03-15. PMID:9887134. |
because low-dose dopamine decreases ahvr and domperidone increases ahvr, the increase in ahvr at altitude may be generated by a decrease in peripheral dopaminergic activity. |
1999-03-15 |
2023-08-12 |
human |
| K Tsuda, S Tsuda, I Nishio, Y Masuyama, M Goldstei. Effects of galanin on dopamine release in the central nervous system of normotensive and spontaneously hypertensive rats. American journal of hypertension. vol 11. issue 12. 1999-03-12. PMID:9880130. |
in addition, to elucidate a possible role of galanin in the regulation of dopaminergic transmission in hypertension, we examined whether the effect of galanin on dopamine release might be altered in the central nervous system of spontaneously hypertensive rats (shr). |
1999-03-12 |
2023-08-12 |
rat |
| K Tsuda, S Tsuda, I Nishio, Y Masuyama, M Goldstei. Effects of galanin on dopamine release in the central nervous system of normotensive and spontaneously hypertensive rats. American journal of hypertension. vol 11. issue 12. 1999-03-12. PMID:9880130. |
furthermore, the greater inhibitory effect of galanin on dopamine release in shr suggests that galanin might actively participate in the regulation of dopaminergic nerve activity in hypertension. |
1999-03-12 |
2023-08-12 |
rat |