| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Schilström, H M Svensson, T H Svensson, G G Nomiko. Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of alpha7 nicotinic receptors in the ventral tegmental area. Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681941. |
we suggest that alpha7 nicotinic receptors in the ventral tegmental area are involved in the acute effect of nicotine on dopamine release in the nucleus accumbens and conclude that the mechanism, by which nicotine stimulates the mesolimbic dopaminergic system, may be an essential constituent of the natural reward-related circuits in brain. |
1998-10-01 |
2023-08-12 |
rat |
| M Dai, J M Teppe. Do silent dopaminergic neurons exist in rat substantia nigra in vivo? Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681948. |
these findings are related to current theories of the mechanisms of action of antipsychotic drugs and the maintenance of near-normal levels of dopamine in the striatum following large-scale loss of nigral dopaminergic neurons. |
1998-10-01 |
2023-08-12 |
rat |
| F Sotty, F Soulière, P Brun, G Chouvet, R Steinberg, P Soubrié, B Renaud, M F Suaud-Chagn. Differential effects of neurotensin on dopamine release in the caudal and rostral nucleus accumbens: a combined in vivo electrochemical and electrophysiological study. Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681955. |
the lowest concentration of neurotensin (10(-7) m) enhanced the extracellular dopamine concentration throughout the nucleus accumbens and stimulated the discharge activity of ventral tegmental area dopaminergic neurons. |
1998-10-01 |
2023-08-12 |
rat |
| F Sotty, F Soulière, P Brun, G Chouvet, R Steinberg, P Soubrié, B Renaud, M F Suaud-Chagn. Differential effects of neurotensin on dopamine release in the caudal and rostral nucleus accumbens: a combined in vivo electrochemical and electrophysiological study. Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681955. |
the two highest concentrations of neurotensin (10(-5) m and 10(-3) m) evoked two patterns of responses on the extracellular dopamine concentration and on the discharge activity of dopaminergic neurons. |
1998-10-01 |
2023-08-12 |
rat |
| F Sotty, F Soulière, P Brun, G Chouvet, R Steinberg, P Soubrié, B Renaud, M F Suaud-Chagn. Differential effects of neurotensin on dopamine release in the caudal and rostral nucleus accumbens: a combined in vivo electrochemical and electrophysiological study. Neuroscience. vol 85. issue 4. 1998-10-01. PMID:9681955. |
these results suggest that variations in extracellular dopamine concentration evoked by neurotensin administration into the ventral tegmental area are the result of neurotensin-evoked changes in dopaminergic activity. |
1998-10-01 |
2023-08-12 |
rat |
| P Hulley, M Schachner, H Lübber. L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671969. |
tritiated dopamine uptake per well and the number of tyrosine hydroxylase-immunopositive neurons increased in a dose-dependent manner with increasing concentrations of l1 antibody, suggesting that l1 acts directly or indirectly as a growth factor for dopaminergic neurons. |
1998-09-24 |
2023-08-12 |
rat |
| P Hulley, M Schachner, H Lübber. L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671969. |
the growth-promoting effects of l1 antibodies on dopaminergic neurons in culture did not appear to be mediated by the camp-activated protein kinase a pathway, since combined treatment with a phosphodiesterase inhibitor had only additive effects on the l1-induced increase of dopamine uptake, and in addition, antibodies against l1 failed to protect cultures of dopaminergic neurons against the neurotoxin mpp+, whereas pretreatment with forskolin and phosphodiesterase type-iv inhibitors was strongly protective. |
1998-09-24 |
2023-08-12 |
rat |
| L Björklund, I Strömber. Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671973. |
chronic treatment with the dopamine antagonist haloperidol increase the neurotrophic activity in striatum, but it is not known how this trophic activity influences different patterns of dopaminergic growth. |
1998-09-24 |
2023-08-12 |
Not clear |
| X M Shen, G Dryhurs. Iron- and manganese-catalyzed autoxidation of dopamine in the presence of L-cysteine: possible insights into iron- and manganese-mediated dopaminergic neurotoxicity. Chemical research in toxicology. vol 11. issue 7. 1998-09-21. PMID:9671546. |
iron- and manganese-catalyzed autoxidation of dopamine in the presence of l-cysteine: possible insights into iron- and manganese-mediated dopaminergic neurotoxicity. |
1998-09-21 |
2023-08-12 |
Not clear |
| T Nagatsu, H Ichinos. [Autosomal-dominant DOPA-responsive dystonia, caused by mutations in the GTP-cyclohydrolase I gene]. Voprosy meditsinskoi khimii. vol 44. issue 3. 1998-09-21. PMID:9703621. |
its deficiency in nigrostriatal dopaminergic neurons cause a decrease in tyrosine hydroxylase activity and therefore dopamine deficiency. |
1998-09-21 |
2023-08-12 |
Not clear |
| W Poelchen, D Sieler, K Inoue, P Ille. Effect of extracellular adenosine 5'-triphosphate on principal neurons of the rat ventral tegmental area. Brain research. vol 800. issue 1. 1998-09-16. PMID:9685629. |
dopaminergic principal cells were identified by their electrophysiological properties and their hyperpolarizing responses to dopamine. |
1998-09-16 |
2023-08-12 |
rat |
| A Feigenspan, S Gustincich, B P Bean, E Raviol. Spontaneous activity of solitary dopaminergic cells of the retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712649. |
because dopamine acts on distant targets in the retina, the pacemaker activity of dopaminergic amacrines may be necessary to ensure a tonic release of the modulator from their dendritic tree. |
1998-09-09 |
2023-08-12 |
mouse |
| Y Maeoka, Y Maegak. [Hyperexcitability of the blink reflex in a child with opsoclonus-myoclonus syndrome]. No to hattatsu = Brain and development. vol 30. issue 4. 1998-09-08. PMID:9695628. |
the hyperexcitability of the blink reflex may indicate the hyperactivity of the neurons in the brainstem reticular formation responsible for the abnormal saccadic eye movements (opsoclonus), which could be caused by the oversecretion of dopamine or by the supersensitivity of dopaminergic receptors. |
1998-09-08 |
2023-08-12 |
Not clear |
| J Zhang, J O Price, D G Graham, T J Montin. Secondary excitotoxicity contributes to dopamine-induced apoptosis of dopaminergic neuronal cultures. Biochemical and biophysical research communications. vol 248. issue 3. 1998-09-08. PMID:9704010. |
dopamine (da) and related catechols may contribute to selective degeneration of dopaminergic neurons in the substantia nigra in parkinson's disease. |
1998-09-08 |
2023-08-12 |
Not clear |
| D G Harden, D King, J M Finlay, A A Grac. Depletion of dopamine in the prefrontal cortex decreases the basal electrophysiological activity of mesolimbic dopamine neurons. Brain research. vol 794. issue 1. 1998-09-02. PMID:9630543. |
one hypothesis regarding the etiology of schizophrenia proposes that disruption of the dopaminergic innervation of the prefrontal cortex leads to an increase in dopamine (da) transmission in subcortical regions. |
1998-09-02 |
2023-08-12 |
rat |
| M A Rossin. Genetic influences on smoking: candidate genes. Environmental health perspectives. vol 106. issue 5. 1998-09-02. PMID:9647893. |
important aspects of the dopaminergic pathway include synthesis of dopamine in dopaminergic neurons, release of dopamine by presynaptic neurons, receptor activation of postsynaptic neurons, dopamine re-uptake by presynaptic neurons, and metabolism of released dopamine. |
1998-09-02 |
2023-08-12 |
Not clear |
| M Jabe. [Dopamine control of neuroendocrine functions. New findings based on the study of transgenic animals]. Annales d'endocrinologie. vol 58. issue 6. 1998-09-01. PMID:9686001. |
the relative contribution of the various dopamine related components is not well established mainly because drugs that target the dopaminergic system often lack selectivity. |
1998-09-01 |
2023-08-12 |
mouse |
| A Mascia, J Afra, J Schoene. Dopamine and migraine: a review of pharmacological, biochemical, neurophysiological, and therapeutic data. Cephalalgia : an international journal of headache. vol 18. issue 4. 1998-08-31. PMID:9642491. |
the most compelling argument favoring an interictal hypersensitivity of dopamine receptors in migraineurs stems from pharmacologic studies of the gastric and autonomic effects of dopaminergic agents such as apomorphine, but none of these studies was blinded and placebo-controlled. |
1998-08-31 |
2023-08-12 |
Not clear |
| S Maisonnette, J P Huston, M Brandao, R K Schwartin. Behavioral asymmetries and neurochemical changes after unilateral lesions of tuberomammillary nucleus or substantia nigra. Experimental brain research. vol 120. issue 3. 1998-08-27. PMID:9628414. |
the ibotenic acid lesions of the pars reticulata did not deplete neostriatal dopamine, indicating that they spared the dopaminergic output of the substantia nigra. |
1998-08-27 |
2023-08-12 |
rat |
| R Djaldetti, E Melame. Management of response fluctuations: practical guidelines. Neurology. vol 51. issue 2 Suppl 2. 1998-08-25. PMID:9711979. |
some are due to central pharmacodynamic mechanisms such as reduced striatal synthesis and storage of dopamine from exogenous levodopa and subsensitization of post synaptic dopaminergic receptors. |
1998-08-25 |
2023-08-12 |
Not clear |