| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teresa Gomez-Isla, Michael C Irizarry, Ami Mariash, Bonnie Cheung, Oscar Soto, Stefanie Schrump, Jesse Sondel, Linda Kotilinek, John Day, Michael A Schwarzschild, Jang-Ho J Cha, Kathy Newell, David W Miller, Kenji Uéda, Anne B Young, Bradley T Hyman, Karen H Ash. Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice. Neurobiology of aging. vol 24. issue 2. 2003-03-26. PMID:12498958. |
despite strong expression of the transgene in the nigra, there was no specific deterioration of the nigrostriatal dopaminergic system as assessed by quantitation of nigral tyrosine hydroxylase (th) containing neurons, striatal th immunoreactivity, dopamine levels, or dopamine receptor number and function. |
2003-03-26 |
2023-08-12 |
mouse |
| Brian M Ross, Robert J Brooks, Margaret Lee, Kathryn S Kalasinsky, Shawn P Vorce, Mary Seeman, Paul J Fletcher, Sylvie D Turenn. Cyclooxygenase inhibitor modulation of dopamine-related behaviours. European journal of pharmacology. vol 450. issue 2. 2003-03-24. PMID:12206852. |
both drugs inhibited catalepsy induced by the dopamine d1-like receptor antagonist r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine (sch23390), the dopamine d2-like receptor antagonist raclopride and by haloperidol, findings in agreement with a dopaminergic effect of cyclooxygenase inhibitors. |
2003-03-24 |
2023-08-12 |
rat |
| Andrea De Laurentiis, Daniel Pisera, Carla Caruso, Marianela Candolfi, Claudia Mohn, Valeria Rettori, Adriana Seilicovic. Lipopolysaccharide- and tumor necrosis factor-alpha-induced changes in prolactin secretion and dopaminergic activity in the hypothalamic-pituitary axis. Neuroimmunomodulation. vol 10. issue 1. 2003-03-21. PMID:12207161. |
since prolactin is mainly under tonic inhibitory control of dopamine, we investigated the effect of lps and tnf-alpha on the hypothalamic-pituitary dopaminergic system. |
2003-03-21 |
2023-08-12 |
Not clear |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
in addition, the increased 5-ht content detected in both the right and left striata observed in this study could be the answer to the behaviors observed and to the early alterations in dopamine in basal ganglia by 2,4-d in neonatal exposed rats, mediated by a serotonergic modulation on the dopaminergic system. |
2003-03-21 |
2023-08-12 |
rat |
| S Thobois, S Corvaisier, P Mertens, C Di Guardo, H Mollion, M Guenot, F Rochefort, G Chazot, M Sindou, E Broussoll. The timing of antiparkinsonian treatment reduction after subthalamic nucleus stimulation. European neurology. vol 49. issue 1. 2003-03-19. PMID:12464720. |
at 12 months postoperatively, one third of the patients no longer received any antiparkinsonian drugs and the others were on monotherapy of either levodopa or dopamine agonists or received a combined treatment of a dopaminergic agonist and levodopa. |
2003-03-19 |
2023-08-12 |
Not clear |
| Douglas S Kim, Richard D Palmite. Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 3. 2003-03-18. PMID:12538862. |
adenosine receptors modulate dopaminergic function by regulating dopamine release in presynaptic neurons and intracellular signaling in postsynaptic striatal neurons. |
2003-03-18 |
2023-08-12 |
mouse |
| Massimo Contini, Elio Raviol. GABAergic synapses made by a retinal dopaminergic neuron. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 3. 2003-03-18. PMID:12547914. |
we suggest that the synapses between retinal dopaminergic neurons and aii amacrine cells are gabaergic and that both gaba and dopamine are released by the presynaptic endings. |
2003-03-18 |
2023-08-12 |
mouse |
| Rebecca J Ralph-Williams, Virginia Lehmann-Masten, Mark A Geye. Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496946. |
although substantial literature describes the modulation of prepulse inhibition (ppi) by dopamine (da) in rats, few reports address the effects of dopaminergic manipulations on ppi in mice. |
2003-03-17 |
2023-08-12 |
mouse |
| Julie Lotharius, Patrik Brundi. Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. Human molecular genetics. vol 11. issue 20. 2003-03-12. PMID:12351575. |
exogenous application of dopamine, as well as redistribution of vesicular dopamine to the cytoplasm, can be toxic to dopaminergic neurons. |
2003-03-12 |
2023-08-12 |
Not clear |
| K Sriram, S A Benkovic, D B Miller, J P O'Callagha. Obesity exacerbates chemically induced neurodegeneration. Neuroscience. vol 115. issue 4. 2003-03-12. PMID:12453501. |
while meth caused dopaminergic nerve terminal degeneration as indicated by decreased striatal dopamine (49%) and tyrosine hydroxylase protein (68%), as well as an increase in glial fibrillary acidic protein by 313% in the lean mice, these effects were exacerbated under the obese condition (96%, 86% and 602%, respectively). |
2003-03-12 |
2023-08-12 |
mouse |
| R Yu Il'yuchenok, N I Dubrovina, E V Popov. Studies of the interaction between behavioral stereotypes and the effects of activation of presynaptic dopamine receptors during extinction and amnesia in mice. Neuroscience and behavioral physiology. vol 32. issue 4. 2003-03-10. PMID:12243257. |
these data on the relationship between the effects of activating presynaptic dopamine receptors in reproduction of the memory trace in conditions of trace disruption on the one hand and behavioral status on the other are assessed from the point of view of different basal levels of dopaminergic system operation in aggressive and submissive mice. |
2003-03-10 |
2023-08-12 |
mouse |
| Masahiko Murata, Michio Suzuki, Kodai Tanaka, Koji Tajiri, Kenji Emori, Masayoshi Kurach. N-methyl-D-aspartate-R1 receptor antisense oligodeoxynucleotide modulates pre- and postsynaptic expression of D2 dopamine receptors in the rat. Neuroscience letters. vol 335. issue 1. 2003-03-06. PMID:12457730. |
to elucidate the relationship between glutamatergic and dopaminergic transmissions, the effects of antisense oligodeoxynucleotide (aodn) to mrna of nr1 subunit of n-methyl-d-aspartate (nmda) receptors on the expression of dopamine d(2) receptors (drd(2)) were examined. |
2003-03-06 |
2023-08-12 |
rat |
| Saber Hussain, Syed F Al. Zinc potentiates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced dopamine depletion in caudate nucleus of mice brain. Neuroscience letters. vol 335. issue 1. 2003-03-06. PMID:12457734. |
mptp is a known neurotoxicant primarily causing marked depletion of dopamine (da) levels in nigrostriatal dopaminergic system. |
2003-03-06 |
2023-08-12 |
mouse |
| Michael J Zigmond, Teresa G Hastings, Ruth G Pere. Increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity? Parkinsonism & related disorders. vol 8. issue 6. 2003-03-05. PMID:12217625. |
increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity? |
2003-03-05 |
2023-08-12 |
Not clear |
| Gonzalo E Torres, Ana Carneiro, Katie Seamans, Chiara Fiorentini, Ava Sweeney, Wei-Dong Yao, Marc G Caro. Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter. The Journal of biological chemistry. vol 278. issue 4. 2003-03-04. PMID:12429746. |
the dopamine transporter (dat) is a presynaptic plasma membrane protein responsible for the termination of dopaminergic neurotransmission in the central nervous system. |
2003-03-04 |
2023-08-12 |
human |
| Aimee Di Marco, Linda S Appiah-Kubi, K Ray Chaudhur. Use of the dopamine agonist cabergoline in the treatment of movement disorders. Expert opinion on pharmacotherapy. vol 3. issue 10. 2003-03-03. PMID:12387694. |
it has been proposed that therapy with cabergoline may mimic physiological dopaminergic stimulation in pd by providing striatal intrasynaptic dopamine replacement. |
2003-03-03 |
2023-08-12 |
Not clear |
| William J Shoemaker, Eva Vavrousek-Jakuba, Cynthia D Arons, Fung Cho Kwo. The acquisition and maintenance of voluntary ethanol drinking in the rat: effects of dopaminergic lesions and naloxone. Behavioural brain research. vol 137. issue 1-2. 2003-03-03. PMID:12445720. |
thus, a lesion of the dopaminergic cell bodies that results in extensive depletion of dopamine in mesolimbic target regions produced no measurable effect on intake of the sweetened ethanol drinks during the acquisition phase of the sucrose-fading paradigm. |
2003-03-03 |
2023-08-12 |
rat |
| C Aurich, T Gerlach, J E Aurich, H-O Hoppen, J Lange, N Parviz. Dopaminergic and opioidergic regulation of gonadotropin and prolactin release in stallions. Reproduction in domestic animals = Zuchthygiene. vol 37. issue 6. 2003-03-03. PMID:12464071. |
thus, in the present study we investigated the dopaminergic regulation of lh and prolactin secretion in stallions, considering interactions between dopamine and opioids. |
2003-03-03 |
2023-08-12 |
Not clear |
| J J Worthington, N M Simon, N B Korbly, R H Perlis, M H Pollac. Ropinirole for antidepressant-induced sexual dysfunction. International clinical psychopharmacology. vol 17. issue 6. 2003-02-25. PMID:12409684. |
dopaminergic agents have been reported to be helpful for the treatment of antidepressant-induced sexual dysfunction and, in this report, we examined the efficacy of the dopamine agonist ropinirole for this indication. |
2003-02-25 |
2023-08-12 |
Not clear |
| Patrick W Awenowicz, Linda L Porte. Local application of dopamine inhibits pyramidal tract neuron activity in the rodent motor cortex. Journal of neurophysiology. vol 88. issue 6. 2003-02-25. PMID:12466459. |
these increases were attenuated significantly (mean= 98% of baseline) by co-application with dopamine in all ptns, indicating dopaminergic interactions with glutamate transmission. |
2003-02-25 |
2023-08-12 |
Not clear |