| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junji Ichikawa, Young Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltze. Cholinergic modulation of basal and amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468043. |
since atypical apds such as clozapine, olanzapine, risperidone, ziprasidone and quetiapine, increase brain acetylcholine as well as dopamine (da) release in a region-specific manner, their effects on cholinergic and dopaminergic neurotransmission may also contribute to various actions of these drugs. |
2003-02-25 |
2023-08-12 |
rat |
| Minoru Narita, Keisuke Mizuo, Hirokazu Mizoguchi, Mamoru Sakata, Michiko Narita, Leon F Tseng, Tsutomu Suzuk. Molecular evidence for the functional role of dopamine D3 receptor in the morphine-induced rewarding effect and hyperlocomotion. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 3. 2003-02-21. PMID:12574430. |
these findings provide further evidence that dopamine d(3) receptor contributes to the postsynaptically negative modulation of the mesolimbic dopaminergic pathway that is associated with the rewarding effect and hyperlocomotion through the stimulation of mu-opioid receptors induced by morphine in the mouse. |
2003-02-21 |
2023-08-12 |
mouse |
| Karin Stiasny, Wolfgang Hermann Oertel, Claudia Trenkwalde. Clinical symptomatology and treatment of restless legs syndrome and periodic limb movement disorder. Sleep medicine reviews. vol 6. issue 4. 2003-02-14. PMID:12531131. |
dopaminergic agents such as levodopa/dopa decarboxylase inhibitor (ddi) and dopamine agonists are considered the treatment of choice for rls and plms. |
2003-02-14 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Differential regulation of somatodendritic and nerve terminal dopamine release by serotonergic innervation of substantia nigra. Journal of neurochemistry. vol 84. issue 3. 2003-02-14. PMID:12558977. |
nigrostriatal dopaminergic neurons release dopamine from dendrites in substantia nigra and axon terminals in striatum. |
2003-02-14 |
2023-08-12 |
Not clear |
| Hideo Saji, Yasuhiko Iida, Hidekazu Kawashima, Mikako Ogawa, Youji Kitamura, Takahiro Mukai, Seiichiro Shimazu, Fumiro Yoned. In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. vol 19. issue 1. 2003-02-13. PMID:12558026. |
thus, we applied the high-resolution spect to in vivo imaging of the brain dopaminergic neurotransmission system in common marmosets using two radiolabeled ligands, [123i]2beta-carbomethoxy-3beta-(4-iodophenyl)tropane (beta-cit) as a dopamine transporter (dat) ligand and [123i]iodobenzamide (ibzm) as a dopamine d2 receptor (d2r) ligand. |
2003-02-13 |
2023-08-12 |
Not clear |
| Boris S Spektor, David W Miller, Zane R Hollingsworth, Yoshio A Kaneko, Steven M Solano, Jennifer M Johnson, John B Penney, Anne B Young, Ruth Luthi-Carte. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain research. Molecular brain research. vol 102. issue 1-2. 2003-02-11. PMID:12191502. |
the diminished expression of d1 and d2 dopamine receptors is a well-documented hallmark of huntington's disease (hd), but relatively little is known about how these changes in receptor populations affect the dopaminergic responses of striatal neurons. |
2003-02-11 |
2023-08-12 |
mouse |
| Hong Qu Yan, Anthony E Kline, Xiecheng Ma, Youming Li, C Edward Dixo. Traumatic brain injury reduces dopamine transporter protein expression in the rat frontal cortex. Neuroreport. vol 13. issue 15. 2003-02-07. PMID:12395087. |
the decrease in dopamine transporter protein levels may reflect a traumatic brain-injury-induced down-regulation of dopamine transporter and/or a loss of dopaminergic fibers. |
2003-02-07 |
2023-08-12 |
rat |
| Davide Viggiano, Daniela Vallone, Hans Welzl, Adolfo G Sadil. The Naples High- and Low-Excitability rats: selective breeding, behavioral profile, morphometry, and molecular biology of the mesocortical dopamine system. Behavior genetics. vol 32. issue 5. 2003-02-07. PMID:12405514. |
morphometric analyses deal with central dopaminergic systems at their origin and target sites, as well as the density of dopamine transporter immunoreactivity. |
2003-02-07 |
2023-08-12 |
rat |
| L Pan. Clinical implications of dopamine research in schizophrenia. Current medical research and opinion. vol 18 Suppl 3. 2003-02-06. PMID:12418605. |
amisulpride preferentially blocks the d2 and d3 subtypes of dopamine receptors, both presynaptically in the frontal cortex, enhancing dopaminergic transmission, and postsynaptically in subcortical areas such as the nucleus accumbens, so reducing dopaminergic transmission. |
2003-02-06 |
2023-08-12 |
Not clear |
| Mark S Brodi. Increased ethanol excitation of dopaminergic neurons of the ventral tegmental area after chronic ethanol treatment. Alcoholism, clinical and experimental research. vol 26. issue 7. 2003-02-05. PMID:12170113. |
chronic ethanol treatment has been reported to alter the in vitro response of dopaminergic neurons to nmda and dopamine. |
2003-02-05 |
2023-08-12 |
mouse |
| Bernard Le Foll, Jorge Diaz, Pierre Sokolof. Increased dopamine D3 receptor expression accompanying behavioral sensitization to nicotine in rats. Synapse (New York, N.Y.). vol 47. issue 3. 2003-02-04. PMID:12494400. |
the mesolimbic dopaminergic system plays a role in this process and a hypersensitivity of postsynaptic neurons of the nucleus accumbens as been proposed as a mechanism, but changes in dopamine d(1) or d(2) receptors have not been demonstrated to date. |
2003-02-04 |
2023-08-12 |
rat |
| J N Joyce, H L Ryoo, T B Beach, J N Caviness, Mark Stacy, E V Gurevich, Mark Reiser, C H Adle. Loss of response to levodopa in Parkinson's disease and co-occurrence with dementia: role of D3 and not D2 receptors. Brain research. vol 955. issue 1-2. 2003-01-31. PMID:12419530. |
thus, loss of dopamine d(3) receptors may be a more important contributing factor to a loss of response to dopaminergic drugs than changes in the d(2) receptor. |
2003-01-31 |
2023-08-12 |
Not clear |
| Hyun Jin Choi, Tae Moo Yoo, Soo Youn Chung, Ji Sun Yang, Joo-Il Kim, Eun Sook Ha, Onyou Hwan. Methamphetamine-induced apoptosis in a CNS-derived catecholaminergic cell line. Molecules and cells. vol 13. issue 2. 2003-01-29. PMID:12018843. |
methamphetamine (meth) causes neurotoxic damages to the dopaminergic system in mammals, but whether it exerts toxicity to dopamine cells in culture has not been fully explored. |
2003-01-29 |
2023-08-12 |
Not clear |
| Chien-Nan Lin, Hsiu-Chih Liu, Shih-Jen Tsai, Tsung-Yun Liu, Chen-Jee Hon. Association study for Parkinson's disease and a dopamine transporter gene polymorphism (1215A/G). European neurology. vol 48. issue 4. 2003-01-28. PMID:12422069. |
the dopamine transporter (dat) may play a role in the pathogenesis of parkinson's disease (pd) because dopamine-specific neurotoxins are taken into dopaminergic nerve terminals via the dat. |
2003-01-28 |
2023-08-12 |
Not clear |
| Hoang N Le, David M Fri. Gene therapy for Parkinson's disease. Expert opinion on biological therapy. vol 2. issue 2. 2003-01-27. PMID:11849115. |
one is the replacement of biosynthetic enzymes for dopamine synthesis and the second strategy is the addition of neurotrophic factors for protection and restoration of dopaminergic neurones. |
2003-01-27 |
2023-08-12 |
human |
| Fernando Antunes, Derick Han, Daniel Rettori, Enrique Cadena. Mitochondrial damage by nitric oxide is potentiated by dopamine in PC12 cells. Biochimica et biophysica acta. vol 1556. issue 2-3. 2003-01-27. PMID:12460681. |
mitochondrial damage in pc12 cells, a model for dopaminergic cells, was examined in terms of the contribution of oxidative stress, nitric oxide (*no), and dopamine to impairment of mitochondrial respiratory control (rc). |
2003-01-27 |
2023-08-12 |
Not clear |
| Fernando Antunes, Derick Han, Daniel Rettori, Enrique Cadena. Mitochondrial damage by nitric oxide is potentiated by dopamine in PC12 cells. Biochimica et biophysica acta. vol 1556. issue 2-3. 2003-01-27. PMID:12460681. |
these data provide further support to the hypothesis that dopamine renders dopaminergic cells more susceptible to the mitochondrial damaging effects of *no. |
2003-01-27 |
2023-08-12 |
Not clear |
| Fernando Antunes, Derick Han, Daniel Rettori, Enrique Cadena. Mitochondrial damage by nitric oxide is potentiated by dopamine in PC12 cells. Biochimica et biophysica acta. vol 1556. issue 2-3. 2003-01-27. PMID:12460681. |
dopamine stored in dopaminergic cells may cause these cells to be more susceptible to the deleterious effects of *no, which involve irreversible impairment of mitochondrial respiration. |
2003-01-27 |
2023-08-12 |
Not clear |
| Juan J Toledo-Aral, Simón Méndez-Ferrer, Ricardo Pardal, Miriam Echevarría, José López-Barne. Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 1. 2003-01-27. PMID:12514210. |
we show that cb glomus cells, although highly dopaminergic, are protected from dopamine-mediated oxidative damage because of the absence of the high-affinity dopamine transporter. |
2003-01-27 |
2023-08-12 |
rat |
| P N Deslandes, D M Pache, R D E Sewel. Drug dependence: neuropharmacology and management. The Journal of pharmacy and pharmacology. vol 54. issue 7. 2003-01-23. PMID:12162706. |
their effects on these pathways (the distinct brain regions making up the mesocorticolimbic dopaminergic system) are predominantly mediated through changes in dopamine neurotransmission, and compounds aimed at selectively modulating these effects may form the basis of drugs to treat addiction. |
2003-01-23 |
2023-08-12 |
Not clear |