| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O M Schlüter, F Fornai, M G Alessandrí, S Takamori, M Geppert, R Jahn, T C Südho. Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice. Neuroscience. vol 118. issue 4. 2003-07-11. PMID:12732244. |
in particular, the levels of synaptic proteins were not altered, and the concentrations of dopamine, dopamine metabolites, and dopaminergic proteins were unchanged. |
2003-07-11 |
2023-08-12 |
mouse |
| Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
the question of whether this is a result of a direct or an indirect effect of ethanol on mesolimbic dopaminergic neurons was examined by investigating the extracellular levels of dopamine and its metabolites in the nucleus accumbens of alcohol-preferring aa (alko alcohol) and alcohol-avoiding ana (alko non-alcohol) rats after application of ethanol locally into either the nucleus accumbens or the ventral tegmental area with the use of reverse microdialysis. |
2003-07-11 |
2023-08-12 |
rat |
| Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
the findings support the suggestion that the increase in the extracellular level of dopamine in the nucleus accumbens after systemic administration of ethanol may involve other sites on dopamine neurons or even different neurotransmitter systems, rather than the action of ethanol at the mesolimbic dopaminergic terminals. |
2003-07-11 |
2023-08-12 |
rat |
| Zhicheng Lin, Ping-Wu Zhang, Xuguang Zhu, Jean-Marc Melgari, Robin Huff, Rachel L Spieldoch, George R Uh. Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. The Journal of biological chemistry. vol 278. issue 22. 2003-07-10. PMID:12660249. |
selective dat expression by dopaminergic neurons has led to use of cocaine analog dat radioligands to assess rates of progression of dopamine neuronal degeneration in parkinson's disease. |
2003-07-10 |
2023-08-12 |
Not clear |
| Lucyna Antkiewicz-Michaluk, Beata Karolewicz, Irena Romańska, Jerzy Michaluk, Andrzej J Bojarski, Jerzy Vetulan. 1-methyl-1,2,3,4-tetrahydroisoquinoline protects against rotenone-induced mortality and biochemical changes in rat brain. European journal of pharmacology. vol 466. issue 3. 2003-07-09. PMID:12694809. |
in summary, we demonstrated that multiple systemic rotenone injections are strongly toxic, and induce alterations of cerebral dopamine metabolism, and that 1metiq may be considered as a potential protective agent against environmental factors affecting the function of the dopaminergic system. |
2003-07-09 |
2023-08-12 |
rat |
| b' Leonid Yavich, Jouni Sirvi\\xc3\\xb6, Antti Haapalinna, Aarne Ylinen, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. Atipamezole, an alpha2-adrenoceptor antagonist, augments the effects of L-DOPA on evoked dopamine release in rat striatum. European journal of pharmacology. vol 462. issue 1-3. 2003-07-02. PMID:12591099.' |
the effects of atipamezole, an alpha(2)-adrenoceptor antagonist, l-3,4-dihydroxyphenylalanine (l-dopa) and the combination of these drugs on dopamine overflow were studied in dopaminergic presynaptic terminals of rat caudate and nucleus accumbens. |
2003-07-02 |
2023-08-12 |
rat |
| Magali Peeters, Jean-Marie Maloteaux, Emmanuel Herman. Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum. Neuroscience letters. vol 343. issue 3. 2003-07-02. PMID:12770697. |
based on our previous work revealing increased function of dopamine receptors and dopamine transporter after amantadine treatment, we studied the effects of repeated memantine administration on dopaminergic neurotransmission. |
2003-07-02 |
2023-08-12 |
rat |
| Shirlee Tan, Bettina Hermann, Emiliana Borrell. Dopaminergic mouse mutants: investigating the roles of the different dopamine receptor subtypes and the dopamine transporter. International review of neurobiology. vol 54. 2003-07-02. PMID:12785287. |
dopaminergic mouse mutants: investigating the roles of the different dopamine receptor subtypes and the dopamine transporter. |
2003-07-02 |
2023-08-12 |
mouse |
| M Matsumoto, C Shannon Weickert, M Akil, B K Lipska, T M Hyde, M M Herman, J E Kleinman, D R Weinberge. Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience. vol 116. issue 1. 2003-06-24. PMID:12535946. |
combined with previous data about protein localization, the present results suggest that the membrane-bound isoform of comt having a high affinity for dopamine is expressed at neuronal dendritic processes in human cortex, consistent with functional evidence that it plays an important role in dopaminergic neurotransmission. |
2003-06-24 |
2023-08-12 |
human |
| A Tofighy, A Abbott, D Centonze, A J Cooper, E Noor, S M Pearce, M Puntis, I M Stanford, M A Wigmore, M G Lace. Excitation by dopamine of rat subthalamic nucleus neurones in vitro-a direct action with unconventional pharmacology. Neuroscience. vol 116. issue 1. 2003-06-24. PMID:12535949. |
this nucleus has a pivotal role in basal ganglia function and voluntary movement control and the possibility that dopamine, and dopaminergic medication used in parkinson's disease, might directly influence its activity is of considerable interest. |
2003-06-24 |
2023-08-12 |
rat |
| R E Myers, L I Anderson, D E Dluze. Estrogen, but not testosterone, attenuates methamphetamine-evoked dopamine output from superfused striatal tissue of female and male mice. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668048. |
accordingly, the sexually dimorphic capacity for estrogen to function as a neuroprotectant may involve a composite of actions upon the nigrostriatal dopaminergic system involving events/sites other than the initial stimulation of dopamine output. |
2003-06-23 |
2023-08-12 |
mouse |
| Elisabeth Jönsson, Viktoria Johansson, Björn Thrandur Björnsson, Svante Winber. Central nervous system actions of growth hormone on brain monoamine levels and behavior of juvenile rainbow trout. Hormones and behavior. vol 43. issue 3. 2003-06-23. PMID:12695109. |
analysis of brain content of monoamines revealed that the gh treatment caused a decrease in the dopamine metabolite homovanillic acid in the hypothalamus, indicating a lowered dopaminergic activity. |
2003-06-23 |
2023-08-12 |
Not clear |
| Rike Zietlow, Simon R Sinclair, Christof J Schwiening, Stephen B Dunnett, James W Fawcett. The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro. Cell transplantation. vol 11. issue 7. 2003-06-18. PMID:12518891. |
the release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro. |
2003-06-18 |
2023-08-12 |
rat |
| Rike Zietlow, Simon R Sinclair, Christof J Schwiening, Stephen B Dunnett, James W Fawcett. The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro. Cell transplantation. vol 11. issue 7. 2003-06-18. PMID:12518891. |
we then assayed the effect of high concentrations of glutamate, aspartate, dopamine, and potassium on dopaminergic neuronal survival in e14 ventral mesencephalic cultures. |
2003-06-18 |
2023-08-12 |
rat |
| Rike Zietlow, Simon R Sinclair, Christof J Schwiening, Stephen B Dunnett, James W Fawcett. The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro. Cell transplantation. vol 11. issue 7. 2003-06-18. PMID:12518891. |
in three-dimensional cultures only the combination of raised potassium, dopamine, glutamate, and aspartate together decreased dopaminergic neuronal survival. |
2003-06-18 |
2023-08-12 |
rat |
| Lauren M Billings, John F Marshal. D2 antagonist-induced c-fos in an identified subpopulation of globus pallidus neurons by a direct intrapallidal action. Brain research. vol 964. issue 2. 2003-06-18. PMID:12576184. |
much research now supports the view that the dopaminergic innervation of the globus pallidus external segment (gp) influences basal ganglia information processing via pallidal dopamine (da) d2, d3, and possibly d1 receptors. |
2003-06-18 |
2023-08-12 |
rat |
| C A Tamminga, A Carlsso. Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis. Current drug targets. CNS and neurological disorders. vol 1. issue 2. 2003-06-18. PMID:12769623. |
partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis. |
2003-06-18 |
2023-08-12 |
Not clear |
| Joong-Seok Kim, Kwang-Soo Lee, Si-Ryung Han, Yong-An Chun. Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 3. 2003-06-17. PMID:12621642. |
decreased striatal dopamine transporter binding assessed by [(123)i]n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane and single photon emission computed tomography ([(123)i]ipt) spect) were observed in the patient, suggesting that osmotic injury causes the demyelination of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of epm with parkinsonism. |
2003-06-17 |
2023-08-12 |
Not clear |
| Junchao Tong, Brian M Ross, Gregory A Schmunk, Frank J Peretti, Kathryn S Kalasinsky, Yoshiaki Furukawa, Lee Cyn Ang, Sally S Aiken, Dennis J Wickham, Stephen J Kis. Decreased striatal dopamine D1 receptor-stimulated adenylyl cyclase activity in human methamphetamine users. The American journal of psychiatry. vol 160. issue 5. 2003-06-17. PMID:12727693. |
it has been assumed that some behavioral changes associated with repeated exposure to dopaminergic psychostimulant drugs might be explained by changes in activity of dopamine receptors, including the dopamine d(1) receptor, which is linked by a stimulatory g protein to the effector enzyme adenylyl cyclase. |
2003-06-17 |
2023-08-12 |
human |
| Roberto W Invernizzi, Claudio Garavaglia, Rosario Samani. The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12644843. |
we assessed how dopaminergic mechanisms were involved in the anticataleptic effect of idazoxan by studying its effect on dopamine (da) release in the striatum, with the microdialysis technique in conscious rats. |
2003-06-11 |
2023-08-12 |
rat |