| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suhail Kasim, H A Jinna. Self-biting induced by activation of L-type calcium channels in mice: dopaminergic influences. Developmental neuroscience. vol 25. issue 1. 2003-10-01. PMID:12876427. |
the ability of +/-bay k 8644 to provoke self-biting and self-injurious behavior was increased by amphetamine and gbr 12909, drugs that augment synaptic dopaminergic concentrations by blocking the reuptake and/or stimulating the release of dopamine. |
2003-10-01 |
2023-08-12 |
mouse |
| Izumi Yamasaki, Tomo Takagi, Daichi Oikawa, Tomoyuki Koutoku, Yusuke Koga, Shozo Tomonaga, Tetsuya Tachibana, Michael D Denbow, Mitsuhiro Furus. Changes in catecholamines and dopaminergic metabolites in pigeon brain during development from the late embryonic stage toward hatch. Zoological science. vol 20. issue 5. 2003-09-29. PMID:12777826. |
thus, the concentrations of the catecholamines norepinephrine (ne), epinephrine (e), and dopamine (da), and the dopaminergic metabolites 3,4-dihydroxyphenylacetic acid (dopac) and 4-hydroxy-3-methoxyphenylacetic acid (hva) were determined at several stages during the late embryonic period (e13, e14, e15, e16, e17 and e18) and the day-of-hatch (p0) in the pigeon telencephalon, cerebellum, optic lobe, and brainstem. |
2003-09-29 |
2023-08-12 |
chicken |
| Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
in this study, we investigated dopamine transporter (dat) density in children with adhd using iodine-123 labelled n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([(123)i]ipt) single-photon emission tomography (spet) and postulated that an alteration in dat density in the basal ganglia is responsible for dopaminergic dysfunction in children with adhd. |
2003-09-26 |
2023-08-12 |
Not clear |
| Pattipati S Naidu, Amanpreet Singh, Shrinivas K Kulkarn. Reversal of haloperidol-induced orofacial dyskinesia by quercetin, a bioflavonoid. Psychopharmacology. vol 167. issue 4. 2003-09-26. PMID:12669184. |
it may be caused by loss of dopaminergic cells, due to free radicals as a product of high synaptic dopamine levels. |
2003-09-26 |
2023-08-12 |
Not clear |
| J Srinivasan, W J Schmid. Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats. The European journal of neuroscience. vol 17. issue 12. 2003-09-24. PMID:12823465. |
decreased dopamine content in the striatum, substantia nigra and pre-frontal cortex was observed after dopaminergic lesion with 6-hydroxydopamine (42.9%). |
2003-09-24 |
2023-08-12 |
rat |
| Roshan Cools, Roger A Barker, Barbara J Sahakian, Trevor W Robbin. L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. Neuropsychologia. vol 41. issue 11. 2003-09-24. PMID:12849761. |
in the current study we investigated the role of dopamine in attentional and socio-emotional functioning by examining effects of withdrawing dopaminergic medication in patients with parkinson's disease (pd). |
2003-09-24 |
2023-08-12 |
Not clear |
| Roshan Cools, Roger A Barker, Barbara J Sahakian, Trevor W Robbin. L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. Neuropsychologia. vol 41. issue 11. 2003-09-24. PMID:12849761. |
hence, these data replicate and extend previous findings that dopaminergic medication improves or impairs cognitive performance depending on the nature of the task and the basal level of dopamine function in underlying cortico-striatal circuitry. |
2003-09-24 |
2023-08-12 |
Not clear |
| Marlene B Lauritsen, Mette Nyegaard, Catalina Betancur, Catherine Colineaux, Trine L Josiassen, Torben A Kruse, Marion Leboyer, Henrik Ewal. Analysis of transmission of novel polymorphisms in the somatostatin receptor 5 (SSTR5) gene in patients with autism. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 121B. issue 1. 2003-09-17. PMID:12898583. |
moreover, the somatostatinergic system interacts with the dopaminergic system, which has been hypothesized to be involved in the etiology of autism; in particular, somatostatin secretion is regulated by dopamine, and the dopamine d2 receptor and the sstr5 receptor interact to form a receptor complex with enhanced functional activity. |
2003-09-17 |
2023-08-12 |
Not clear |
| Carrie L Heusner, Thomas S Hnasko, Mark S Szczypka, Yuhong Liu, Matthew J During, Richard D Palmite. Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867267. |
dopamine deficient (dd) mice, in which tyrosine hydroxylase (th) has been specifically inactivated in dopaminergic neurons, have a blunted response to amphetamine, indicating that the hyperlocomotive response requires dopamine. |
2003-09-16 |
2023-08-12 |
mouse |
| C Warren Olano. The role of dopamine agonists in the treatment of early Parkinson's disease. Neurology. vol 58. issue 4 Suppl 1. 2003-09-15. PMID:11909983. |
furthermore, several lines of laboratory research suggest that dopamine agonists might protect dopaminergic neurons in pd and retard the rate of disease progression. |
2003-09-15 |
2023-08-12 |
Not clear |
| Charles R Cantor, Matthew B Ster. Dopamine agonists and sleep in Parkinson's disease. Neurology. vol 58. issue 4 Suppl 1. 2003-09-15. PMID:11909988. |
this adverse effect may be a dose-related phenomenon that is somewhat more likely to occur with dopamine agonists than with levodopa, although all dopaminergic drugs can be sedating. |
2003-09-15 |
2023-08-12 |
Not clear |
| Charles R Cantor, Matthew B Ster. Dopamine agonists and sleep in Parkinson's disease. Neurology. vol 58. issue 4 Suppl 1. 2003-09-15. PMID:11909988. |
although we have characterized the sleep disturbances in pd, further investigation is needed to define their prevalence and etiology, particularly with respect to the role of dopamine and dopaminergic agents. |
2003-09-15 |
2023-08-12 |
Not clear |
| K Fuxe, K X Jacobsen, M Höistad, B Tinner, A Jansson, W A Staines, L F Agnat. The dopamine D1 receptor-rich main and paracapsular intercalated nerve cell groups of the rat amygdala: relationship to the dopamine innervation. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809694. |
dopaminergic projections to the main and paracapsular intercalated islands were examined by determining the relationship of the dopamine nerve-terminal networks to the d1-receptor immunoreactive staining of cells within the intercalated islands, using double-fluorescence immunolabelling procedures in combination with confocal laser microscopy. |
2003-09-12 |
2023-08-12 |
rat |
| K Fuxe, K X Jacobsen, M Höistad, B Tinner, A Jansson, W A Staines, L F Agnat. The dopamine D1 receptor-rich main and paracapsular intercalated nerve cell groups of the rat amygdala: relationship to the dopamine innervation. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809694. |
the microscopy and image analysis revealed that there was only a minor dopaminergic innervation of the d1 receptor-immunoreactive cells in the rostromedial and caudal component of the main intercalated island, suggesting volume transmission as the main communication mode for dopamine in these regions. |
2003-09-12 |
2023-08-12 |
rat |
| K Fuxe, K X Jacobsen, M Höistad, B Tinner, A Jansson, W A Staines, L F Agnat. The dopamine D1 receptor-rich main and paracapsular intercalated nerve cell groups of the rat amygdala: relationship to the dopamine innervation. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809694. |
in contrast, the d1 receptor-immunoreactive areas in the rostrolateral part of the main island and also the paracapsular intercalated islands showed a high degree of dopaminergic innervation, indicating that synaptic and perisynaptic dopamine transmission plays a dominant role in these regions. |
2003-09-12 |
2023-08-12 |
rat |
| Keiko Shimizu, Kazuo Matsubara, Ko-ichi Ohtaki, Hiroshi Shion. Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture. Neuroscience research. vol 46. issue 4. 2003-09-12. PMID:12871774. |
since this damage was prevented by gbr-12909, the dopamine transporter could be an initial step of the pq induced dopaminergic neurotoxicity. |
2003-09-12 |
2023-08-12 |
rat |
| Keiko Shimizu, Kazuo Matsubara, Ko-ichi Ohtaki, Hiroshi Shion. Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture. Neuroscience research. vol 46. issue 4. 2003-09-12. PMID:12871774. |
the sequential treatments with lower pq and 1-methyl-4-phenyl pyridinium (mpp+) doses, where each dose alone was not lethal, markedly killed dopamine neurons, suggesting that the exposure of a lower dose of pq could lead to the vulnerability of dopaminergic neurons. |
2003-09-12 |
2023-08-12 |
rat |
| Ippolita Cantuti-Castelvetri, Barbara Shukitt-Hale, James A Josep. Dopamine neurotoxicity: age-dependent behavioral and histological effects. Neurobiology of aging. vol 24. issue 5. 2003-09-12. PMID:12885577. |
the dopaminergic system is particularly vulnerable to ros, and dopamine (da) itself can be an endogenous source of ros. |
2003-09-12 |
2023-08-12 |
rat |
| Richard Nass, Randy D Blakel. The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration. Annual review of pharmacology and toxicology. vol 43. 2003-09-09. PMID:12415122. |
the caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration. |
2003-09-09 |
2023-08-12 |
caenorhabditis_elegans |
| Cristina Bäckman, Zhi Bing You, Thomas Perlmann, Barry J Hoffe. Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine. Behavioural brain research. vol 143. issue 1. 2003-09-09. PMID:12842300. |
gene targeting experiments, in which both alleles of the nurr1 gene were deleted, have shown that this molecule plays an essential role in the development of midbrain dopaminergic neurons, as shown by the loss of dopaminergic markers and the neurotransmitter dopamine (da) in the ventral mesencephalon of nurr1 null mutant mice. |
2003-09-09 |
2023-08-12 |
mouse |