| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian P Bergstrom, Paul A Garri. "Passive stabilization" of striatal extracellular dopamine across the lesion spectrum encompassing the presymptomatic phase of Parkinson's disease: a voltammetric study in the 6-OHDA-lesioned rat. Journal of neurochemistry. vol 87. issue 5. 2003-12-18. PMID:14622102. |
electrical stimulation was used to elicit extracellular dopamine levels mimicking the steady-state dynamics of tonic dopaminergic signaling. |
2003-12-18 |
2023-08-12 |
rat |
| G Neves, R Fenner, A P Heckler, A F Viana, L Tasso, R Menegatti, C A M Fraga, E J Barreiro, T Dalla-Costa, S M K Rate. Dopaminergic profile of new heterocyclic N-phenylpiperazine derivatives. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 36. issue 5. 2003-12-17. PMID:12715082. |
the aim of the present study was to report the structural design of two n-phenylpiperazine derivatives, compound 4: 1-[1-(4-chlorophenyl)-1h-4-pyrazolylmethyl]-4-phenylhexahydropyrazine and compound 5: 1-[1-(4-chlorophenyl)-1h-1,2,3-triazol-4-ylmethyl]-4-phenylhexahydropyrazine, planned to be dopamine ligands, and their dopaminergic action profile. |
2003-12-17 |
2023-08-12 |
mouse |
| Firoj Hossain Khan, Tanusree Sen, Sasanka Chakrabart. Dopamine oxidation products inhibit Na+, K+-ATPase activity in crude synaptosomal-mitochondrial fraction from rat brain. Free radical research. vol 37. issue 6. 2003-12-16. PMID:12868486. |
the diverse damaging effects of dopamine (da) oxidation products on brain subcellular components including mitochondrial electron transport chain have been implicated in dopaminergic neuronal death in parkinson's disease. |
2003-12-16 |
2023-08-12 |
rat |
| Iwona E Misiuta, Lynn Anderson, Michael P McGrogan, Paul R Sanberg, Alison E Willing, Tanja Zigov. The transcription factor Nurr1 in human NT2 cells and hNT neurons. Brain research. Developmental brain research. vol 145. issue 1. 2003-12-16. PMID:14519498. |
our previous in vitro experiments showed that hnt cells possess immunocytochemically detectable markers typical of dopaminergic (da) ventral mesencephalic (vm) neurons, including tyrosine hydroxylase (th), dopamine transporter (dat), dopamine receptor (d2), and aldehyde dehydrogenase (ahd-2). |
2003-12-16 |
2023-08-12 |
human |
| Dhanasekharan Muralikrishnan, Supriti Samantaray, Kochupurackal P Mohanakuma. D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity. Synapse (New York, N.Y.). vol 50. issue 1. 2003-12-12. PMID:12872288. |
the potency of d-deprenyl to scavenge mptp-induced.oh in vivo and to render protection against the dopaminergic neurotoxicity without affecting dopamine turnover, mao-b activity, or formation of mpp(+) in the brain indicates a direct involvement of.oh in the neurotoxic action of mptp and antioxidant effect in the neuroprotective action of deprenyl. |
2003-12-12 |
2023-08-12 |
mouse |
| Satoru Otani, Hérve Daniel, Marie-Paule Roisin, Francis Crepe. Dopaminergic modulation of long-term synaptic plasticity in rat prefrontal neurons. Cerebral cortex (New York, N.Y. : 1991). vol 13. issue 11. 2003-12-12. PMID:14576216. |
the presence of dopamine in the bathing medium facilitates ltd in slice preparations, whereas in the anesthetized intact brain, dopamine released from dopaminergic axon terminals in the prefrontal cortex facilitates ltp. |
2003-12-12 |
2023-08-12 |
rat |
| Claudio Bassetti, Sandra Clavadetscher, Matthias Gugger, Christian W Hes. Pergolide-associated 'sleep attacks' in a patient with restless legs syndrome. Sleep medicine. vol 3. issue 3. 2003-12-12. PMID:14592219. |
the appearance of 'sleep attacks' as a 'withdrawal' effect of pergolide is consistent with a wakefulness-promoting action of postsynaptic dopaminergic receptors at higher doses of dopamine agonists. |
2003-12-12 |
2023-08-12 |
Not clear |
| Grzegorz Sulkowski, Lidia Struzyńska, Aleksandra Lenkiewicz, Sławomir Januszewski, Urszula Rafałowsk. Lack of recovery in K+-dependent dopamine release and D2 receptor binding after cardiac arrest and reperfusion. Folia neuropathologica. vol 41. issue 3. 2003-12-12. PMID:14604294. |
lack of possibility to recover dopamine release and activity of dopamine d2 receptor after 7 days post-reperfusion can be associated with irreversible injury of dopaminergic neurones, which can be involved in several dysfunctions of the brain. |
2003-12-12 |
2023-08-12 |
Not clear |
| Huo Shen, Kazuya Kannari, Hiroshi Yamato, Akira Arai, Muneo Matsunag. Effects of benserazide on L-DOPA-derived extracellular dopamine levels and aromatic L-amino acid decarboxylase activity in the striatum of 6-hydroxydopamine-lesioned rats. The Tohoku journal of experimental medicine. vol 199. issue 3. 2003-12-05. PMID:12703659. |
we determined the influence of benserazide on the central aadc activity in rats with dopaminergic denervation and observed changes in extracellular dopamine (da) levels after benserazide and l-dopa administration. |
2003-12-05 |
2023-08-12 |
rat |
| Lee Zuckerman, Moshe Rehavi, Rachel Nachman, Ina Weine. Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 10. 2003-12-05. PMID:12865897. |
in addition, prenatal immune activation led to a postpubertal emergence of increased sensitivity to the locomotor-stimulating effects of amphetamine and increased in vitro striatal dopamine release, as well as to morphological alterations in the hippocampus and the entorhinal cortex in the adult offspring, consistent with the well-documented mesolimbic dopaminergic and temporolimbic pathology in schizophrenia. |
2003-12-05 |
2023-08-12 |
rat |
| C Gambarana, F Masi, B Leggio, S Grappi, G Nanni, S Scheggi, M G De Montis, A Tagliamont. Acquisition of a palatable-food-sustained appetitive behavior in satiated rats is dependent on the dopaminergic response to this food in limbic areas. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946710. |
in order to investigate the role of food-induced dopamine release in vab acquisition, we studied by microdialysis the dopaminergic response in the nacs and mpfc to the presentation and consumption of vs in satiated control rats, and in satiated rats exposed to repeated stress or lithium treatment. |
2003-12-05 |
2023-08-12 |
rat |
| F Bergquist, H Nissbrand. Influence of R-type (Cav2.3) and t-type (Cav3.1-3.3) antagonists on nigral somatodendritic dopamine release measured by microdialysis. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895515. |
the release of dopamine from soma and dendrites of dopaminergic neurons in substantia nigra has been reported to be calcium-dependent, but it remains to be determined which calcium channels mediate this effect. |
2003-12-04 |
2023-08-12 |
rat |
| Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chessele. Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats. The Journal of comparative neurology. vol 465. issue 1. 2003-12-04. PMID:12926013. |
interestingly, regions with early pathology all receive dense dopaminergic inputs, supporting accumulating evidence for a role of dopamine in hd pathology. |
2003-12-04 |
2023-08-12 |
mouse |
| Zhizhong Dong, Boris Ferger, Jean-Charles Paterna, Denise Vogel, Sven Furler, Maribel Osinde, Joram Feldon, Hansruedi Büele. Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 21. 2003-12-04. PMID:14530399. |
here we show that recombinant adeno-associated virus-mediated cdcrel-1 gene transfer to the substantia nigra of rats results in a rapid onset (6-10 days) of nigral and striatal cdcrel-1 expression that is followed by a progressive loss of nigral dopaminergic neurons and a decline of the striatal dopamine levels. |
2003-12-04 |
2023-08-12 |
rat |
| Kalervo Kiianmaa, Petri Hyytiä, Herman H Samson, Jörgen A Engel, Lennart Svensson, Bo Söderpalm, Anna Larsson, Giancarlo Colombo, Giovanni Vacca, Deborah A Finn, Ryan K Bachtell, Andrey E Ryabini. New neuronal networks involved in ethanol reinforcement. Alcoholism, clinical and experimental research. vol 27. issue 2. 2003-12-02. PMID:12605070. |
the presentations were (1) the role of opioidergic and dopaminergic networks in ethanol-seeking behavior, by kalervo kiianmaa and petri hyytiä; (2) interaction between the dopamine systems in the prefrontal cortex and nucleus accumbens during ethanol self-administration, by herman h. samson; (3) neurochemical and behavioral studies on ethanol and nicotine interactions, by jörgen a. engel, lennart svensson, bo söderpalm, and anna larsson; (4) involvement of the gaba receptor in alcohol reinforcement in sp rats, by giancarlo colombo and giovanni vacca; (5) neuroactive steroids and ethanol reinforcement, by deborah a. finn, and (6) potential contribution of the urocortin system to regulation of alcohol self-administration, by andrey e. ryabinin and ryan k. |
2003-12-02 |
2023-08-12 |
rat |
| Jenice D'Costa, Judith Harvey-White, Pankaj Qasba, Advait Limaye, Christine R Kaneski, Alberta Davis-Warren, Roscoe O Brady, Krys S Bankiewicz, Eugene O Major, Suresh K Ary. HIV-2 derived lentiviral vectors: gene transfer in Parkinson's and Fabry disease models in vitro. Journal of medical virology. vol 71. issue 2. 2003-11-25. PMID:12938190. |
parkinson's disease is a focal degeneration of dopaminergic neurons in the brain with progressive loss of ability to produce the neurotransmitter dopamine. |
2003-11-25 |
2023-08-12 |
Not clear |
| John W Haycock, Laurence Becker, Lee Ang, Yoshiaki Furukawa, Oleh Hornykiewicz, Stephen J Kis. Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535941. |
marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. |
2003-11-24 |
2023-08-12 |
human |
| John W Haycock, Laurence Becker, Lee Ang, Yoshiaki Furukawa, Oleh Hornykiewicz, Stephen J Kis. Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535941. |
because age-related changes in brain dopaminergic innervation are assumed to influence human disorders involving dopamine (da), we measured the levels of several presynpatic daergic markers [da, homovanillic acid, tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), vesicular monoamine transporter 2 (vmat2), and dopamine transporter (dat)] in post-mortem human striatum (caudate and putamen) from 56 neurologically normal subjects aged 1 day to 103 years. |
2003-11-24 |
2023-08-12 |
human |
| M Gruss, J Bock, K Brau. Haloperidol impairs auditory filial imprinting and modulates monoaminergic neurotransmission in an imprinting-relevant forebrain area of the domestic chick. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535951. |
the results revealed that: (i) the systemic application of the potent dopamine receptor antagonist haloperidol (7.5 mg/kg) strongly impairs auditory filial imprinting; (ii) systemic haloperidol induces a tetrodotoxin-sensitive increase of extracellular levels of the dopamine metabolite, homovanillic acid, in the mnh, whereas the levels of glutamate, taurine and the serotonin metabolite, 5-hydroxyindole-3-acetic acid, remain unchanged; (iii) haloperidol (0.01, 0.1, 1 mm) infused locally into the mnh increases glutamate, taurine and 5- hydroxyindole-3-acetic acid levels in a dose-dependent manner, whereas homovanillic acid levels remain unchanged; (iv) systemic haloperidol infusion reinforces the n-methyl-d-aspartate receptor-mediated inhibitory modulation of the dopaminergic neurotransmission within the mnh. |
2003-11-24 |
2023-08-12 |
chicken |
| Jerzy Vetulani, Lucyna Antkiewicz-Michaluk, Irena Nalepa, Mario Sanson. A possible physiological role for cerebral tetrahydroisoquinolines. Neurotoxicity research. vol 5. issue 1-2. 2003-11-21. PMID:12832229. |
the results indicate that salsolinol and tiq act as specific antagonists of agonistic conformation of dopamine receptors, and owing to that may play a role of endogenous feed-back regulators of the dopaminergic system. |
2003-11-21 |
2023-08-12 |
mouse |