| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carl E Clark. Neuroprotection and pharmacotherapy for motor symptoms in Parkinson's disease. The Lancet. Neurology. vol 3. issue 8. 2004-08-30. PMID:15261607. |
dopamine agonists can be used as an alternative initial therapy to delay the onset of motor complications but at the expense of more dopaminergic adverse events, poorer control of motor symptoms, and increased cost. |
2004-08-30 |
2023-08-12 |
Not clear |
| Pattipati S Naidu, Amanpreet Singh, Shrinivas K Kulkarn. Reversal of reserpine-induced orofacial dyskinesia and cognitive dysfunction by quercetin. Pharmacology. vol 70. issue 2. 2004-08-23. PMID:14685008. |
it may be caused by a loss of dopaminergic cells or may be due to free radicals as a product of high synaptic dopamine levels. |
2004-08-23 |
2023-08-12 |
rat |
| Carlo Cavallotti, Daniela Cavallotti, Gianfranco Tonnarini, Francesca Maria Tranquilli Leal. Dopamine receptors in the human dura mater. Neurochemical research. vol 29. issue 8. 2004-08-19. PMID:15260126. |
dopamine receptors (dar) were studied as a component of the nervous dopaminergic system in the human dura mater. |
2004-08-19 |
2023-08-12 |
human |
| Manuel Miranda, Tatiana Sorkina, Tom N Grammatopoulos, W Michael Zawada, Alexander Sorki. Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum. The Journal of biological chemistry. vol 279. issue 29. 2004-08-17. PMID:15128747. |
the plasma membrane dopamine transporter (dat) has an essential role in terminating dopaminergic neurotransmission by reuptake of dopamine into the presynaptic neurons. |
2004-08-17 |
2023-08-12 |
rat |
| Amanpreet Singh, Pattipati S Naidu, Shrinivas K Kulkarn. Possible antioxidant and neuroprotective mechanisms of FK506 in attenuating haloperidol-induced orofacial dyskinesia. European journal of pharmacology. vol 477. issue 2. 2004-08-11. PMID:14519411. |
it may be caused by a loss of dopaminergic cells, due to free radicals as a product of high synaptic dopamine levels. |
2004-08-11 |
2023-08-12 |
rat |
| SunRyeo Beom, Dawoon Cheong, Gonzalo Torres, Marc G Caron, Kyeong-Man Ki. Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase. The Journal of biological chemistry. vol 279. issue 27. 2004-08-11. PMID:15102843. |
dopamine d(2) and d(3) receptors (d(2)r/d(3)r), which have similar structural architecture as well as functional similarities, are expressed in the same brain dopaminergic neurons. |
2004-08-11 |
2023-08-12 |
Not clear |
| Michael R Littner, Clete Kushida, W McDowell Anderson, Dennis Bailey, Richard B Berry, Max Hirshkowitz, Sheldon Kapen, Milton Kramer, Teofilo Lee-Chiong, Kasey K Li, Daniel L Loube, Timothy Morgenthaler, Merrill Wis. Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep. vol 27. issue 3. 2004-08-11. PMID:15164914. |
dopaminergic agents, particularly dopamine agonists, have been used with increasing frequency in the treatment of restless legs syndrome and periodic limb movement disorder. |
2004-08-11 |
2023-08-12 |
Not clear |
| Michael R Littner, Clete Kushida, W McDowell Anderson, Dennis Bailey, Richard B Berry, Max Hirshkowitz, Sheldon Kapen, Milton Kramer, Teofilo Lee-Chiong, Kasey K Li, Daniel L Loube, Timothy Morgenthaler, Merrill Wis. Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep. vol 27. issue 3. 2004-08-11. PMID:15164914. |
other dopamine agonists (talipexole, cabergoline, piribidel, and alpha-dihydroergocryptine) and the dopaminergic agents amantadine and selegiline may be effective in the treatment of rls and plmd, but the level of effectiveness of these medications is not currently established. |
2004-08-11 |
2023-08-12 |
Not clear |
| Ki-Hwan Lee, Mi-Young Kim, Dong-Hwan Kim, Yong-Sung Le. Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter. Neurochemical research. vol 29. issue 7. 2004-08-10. PMID:15202772. |
the dopamine transporter (dat) regulates the extent and duration of dopamine receptor activation through sodium-dependant reuptake of dopamine into presynaptic neurons, resulting in termination of dopaminergic neurotransmission. |
2004-08-10 |
2023-08-12 |
human |
| Opa Vajragupta, Preecha Boonchoong, Hiroshi Watanabe, Michihisa Tohda, Naparat Kummasud, Yaowared Sumanon. Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity. Free radical biology & medicine. vol 35. issue 12. 2004-08-09. PMID:14680686. |
in addition, treatment of acylcpcpx and curcumin significantly attenuated mptp-induced striatal dopamine depletion in mice, which was in accordance with the increase in the density of dopaminergic neurons when compared with mptp-treated mice. |
2004-08-09 |
2023-08-12 |
mouse |
| J S Lonstein, J D Blaustei. Immunocytochemical investigation of nuclear progestin receptor expression within dopaminergic neurones of the female rat brain. Journal of neuroendocrinology. vol 16. issue 6. 2004-08-06. PMID:15189328. |
additionally, although progesterone alters mesolimbic and nigrostriatal dopamine release, and the numerous behaviours that these pathways influence, these data again suggest that it does not do so via nuclear progestin receptor in dopaminergic cells of the ventral tegmental area and substantia nigra. |
2004-08-06 |
2023-08-12 |
rat |
| Andrew H Evans, Regina Katzenschlager, Dominic Paviour, John D O'Sullivan, Silke Appel, Andrew D Lawrence, Andrew J Lee. Punding in Parkinson's disease: its relation to the dopamine dysregulation syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 4. 2004-08-05. PMID:15077237. |
punding was associated with very high doses of dopamine replacement therapy often related to a pattern of chronic inappropriate overuse of dopaminergic medication. |
2004-08-05 |
2023-08-12 |
Not clear |
| Benjamin Gauter, Roman Rukwied, Christoph Konra. Cannabinoid agonists in the treatment of blepharospasm--a case report study. Neuro endocrinology letters. vol 25. issue 1-2. 2004-08-03. PMID:15159681. |
in the brain a dense co-localisation of cannabinoid (cb1) and dopamine (d2)-receptor was identified which had been associated with the influence of cannabinoids on the dopaminergic reward system. |
2004-08-03 |
2023-08-12 |
Not clear |
| Laurent Galineau, Ercem Kodas, Denis Guilloteau, Marie-Paule Vilar, Sylvie Chalo. Ontogeny of the dopamine and serotonin transporters in the rat brain: an autoradiographic study. Neuroscience letters. vol 363. issue 3. 2004-08-02. PMID:15182957. |
we investigated the maturation of the dopamine and serotonin transporters in rat cerebral regions containing the soma and projections of dopaminergic and serotoninergic neurons in an extensive study from the end of embryonic life (e(18)) to adult stages (until p(70)). |
2004-08-02 |
2023-08-12 |
rat |
| M Jenuwein, C Scheller, E Neuen-Jacob, S Sopper, T Tatschner, V ter Meulen, P Riederer, E Koutsilier. Dopamine deficits and regulation of the cAMP second messenger system in brains of simian immunodeficiency virus-infected rhesus monkeys. Journal of neurovirology. vol 10. issue 3. 2004-08-02. PMID:15204921. |
the results suggest that dopamine defects precede neurologic deficits and implicate dysfunction of the dopaminergic system in the etiopathogenesis of hiv dementia. |
2004-08-02 |
2023-08-12 |
human |
| Susanne Nikolaus, Markus Beu, Andreas Wirrwar, Henning Vosberg, Hans-Wilhelm Müller, Rolf Larisc. The contribution of small animal positron emission tomography to the neurosciences--a critical evaluation. Reviews in the neurosciences. vol 15. issue 2. 2004-07-28. PMID:15202685. |
relevant findings pertain to the relationship of brain metabolism/perfusion and the cholinergic system, the regulation state of dopamine receptors upon cocaine administration and withdrawal, the regulation state of dopamine receptors and transporters in animal models of parkinson's and huntington's disease, and potential treatments of progressive dopaminergic depletion with adenoviral vectors, embryonic grafts, stem cells and nerve growth factors. |
2004-07-28 |
2023-08-12 |
rat |
| Alberto Del Arco, Shunwei Zhu, Anton Terasmaa, Abdul H Mohammed, Kjell Fux. Hyperactivity to novelty induced by social isolation is not correlated with changes in D2 receptor function and binding in striatum. Psychopharmacology. vol 171. issue 2. 2004-07-27. PMID:13680076. |
while these behavioral changes have been partly related to a dysregulation of dopaminergic activity in striatum (dorsal and ventral), the involvement of changes in the function of dopamine receptors is still a matter of controversy. |
2004-07-27 |
2023-08-12 |
Not clear |
| Wen-Sheng Huang, Meei-Shyuan Lee, Jiann-Chyun Lin, Cheng-Yu Chen, Yu-Wen Yang, Shinn-Zong Lin, Shiaw-Pyng We. Usefulness of brain 99mTc-TRODAT-1 SPET for the evaluation of Parkinson's disease. European journal of nuclear medicine and molecular imaging. vol 31. issue 2. 2004-07-23. PMID:15129696. |
the extent of the degeneration of the dopaminergic system in pd can be visualised by dopamine transporter imaging using single-photon emission tomography (spet). |
2004-07-23 |
2023-08-12 |
Not clear |
| Marten P Smidt, Simone M Smits, J Peter H Burbac. Molecular mechanisms underlying midbrain dopamine neuron development and function. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623352. |
furthermore, we discuss the consequences of changes in dopamine homeostasis for the function of the mesencephalic dopaminergic system. |
2004-07-22 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
upstream of the dopaminergic neurons nicotine induces long-term potentiation of the excitatory input to dopamine cells in the ventral tegmental area, and depresses inhibitory inputs. |
2004-07-22 |
2023-08-12 |
Not clear |