| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tae-Eun Jin, Miae Jang, Hyunjung Kim, Yu Mi Choi, Hana Cho, Sungkwon Chung, Myoung Kyu Par. Involvement of corticotropin-releasing factor receptor 2 beta in differentiation of dopaminergic MN9D cells. Molecules and cells. vol 26. issue 3. 2008-10-30. PMID:18511879. |
here we used dopaminergic neuron-derived mn9d cells to investigate the function of crf receptor 2 in dopamine neurons. |
2008-10-30 |
2023-08-12 |
Not clear |
| Akinori Nishi, Mahomi Kuroiwa, Diane B Miller, James P O'Callaghan, Helen S Bateup, Takahide Shuto, Naoki Sotogaku, Takaichi Fukuda, Nathaniel Heintz, Paul Greengard, Gretchen L Snyde. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 42. 2008-10-29. PMID:18923023. |
the pde4 inhibitor, rolipram, induced a large increase in th ser40 phosphorylation at dopaminergic terminals that was associated with a commensurate increase in dopamine synthesis and turnover in striatum in vivo. |
2008-10-29 |
2023-08-12 |
mouse |
| Masahiko Watabe, Toshio Nakak. Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells. Molecular pharmacology. vol 74. issue 4. 2008-10-27. PMID:18599602. |
we have reported dopamine redistribution from vesicles to the cytosol to play a crucial role in selective dopaminergic cell apoptosis. |
2008-10-27 |
2023-08-12 |
human |
| Masahiko Watabe, Toshio Nakak. Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells. Molecular pharmacology. vol 74. issue 4. 2008-10-27. PMID:18599602. |
in the present study, we investigated how rotenone causes dopamine redistribution to the cytosol using an in vitro model of human dopaminergic sh-sy5y cells. |
2008-10-27 |
2023-08-12 |
human |
| Masahiko Watabe, Toshio Nakak. Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells. Molecular pharmacology. vol 74. issue 4. 2008-10-27. PMID:18599602. |
our findings demonstrate that nitration of the tyrosine residues of vmat2 by rotenone leads to both functional inhibition and accumulation of aggregate-like formations of vmat2 and consequently to the redistribution of dopamine to the cytosol and apoptosis of dopaminergic sh-sy5y cells. |
2008-10-27 |
2023-08-12 |
human |
| Jean-Claude Dreher, Andreas Meyer-Lindenberg, Philip Kohn, Karen Faith Berma. Age-related changes in midbrain dopaminergic regulation of the human reward system. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 39. 2008-10-24. PMID:18794529. |
significant losses over a normal lifespan have been reported for dopamine receptors and transporters, but very little is known about the neurofunctional consequences of this age-related dopaminergic decline. |
2008-10-24 |
2023-08-12 |
human |
| Mary F Kritzer, Lela M Creut. Region and sex differences in constituent dopamine neurons and immunoreactivity for intracellular estrogen and androgen receptors in mesocortical projections in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 38. 2008-10-22. PMID:18799684. |
this study explored possible substrates for this in two ways: by comparing the distributions of immunoreactivity for intracellular estrogen (alpha and beta) and androgen receptors among retrogradely labeled dopaminergic and nondopaminergic mesocortical neurons projecting to prefrontal, premotor, and primary motor cortices, areas in which male rat dopamine axons are differentially hormone-sensitive; and by comparing anatomical data in males and females. |
2008-10-22 |
2023-08-12 |
rat |
| Mary F Kritzer, Lela M Creut. Region and sex differences in constituent dopamine neurons and immunoreactivity for intracellular estrogen and androgen receptors in mesocortical projections in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 38. 2008-10-22. PMID:18799684. |
it was also found that the proportions of dopamine neurons making up mesocortical projections were approximately 30% in males, whereas in females, significantly more constituent cells were dopaminergic. |
2008-10-22 |
2023-08-12 |
rat |
| Akira Arai, Masahiko Tomiyama, Kazuya Kannari, Tamaki Kimura, Chieko Suzuki, Mitsunori Watanabe, Takeshi Kawarabayashi, Huo Shen, Mikio Shoj. Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine transporter. Synapse (New York, N.Y.). vol 62. issue 8. 2008-10-20. PMID:18509855. |
this study provides evidence that l-dopa-derived da is taken up by the norepinephrine transporter, instead of the dopamine transporter, in the striatum with dopaminergic denervation. |
2008-10-20 |
2023-08-12 |
rat |
| Bernard Le Foll, Zuzana Justinova, Gianlugi Tanda, Steven R Goldber. [Future medications for tobacco and cannabis dependence]. Bulletin de l'Academie nationale de medecine. vol 192. issue 1. 2008-10-16. PMID:18663981. |
here we review recent results obtained with antagonists targeting cannabinoid cb1 receptors, dopamine d3 receptors and opioid receptors, that directly or indirectly modulate dopaminergic transmission. |
2008-10-16 |
2023-08-12 |
Not clear |
| Diego Bustamante, Maria Elena Quintanilla, Lutske Tampier, Victor Gonzalez-Lira, Yedy Israel, Mario Herrera-Marschit. Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats. European journal of pharmacology. vol 591. issue 1-3. 2008-10-15. PMID:18611399. |
overall, the present results suggest that a low dopaminergic tone and a strong mesolimbic dopamine response to ethanol are concerted neurochemical features associated to an ethanol-seeking behaviour in rats. |
2008-10-15 |
2023-08-12 |
rat |
| S Kushida, K Kimoto, N Hori, M Toyoda, N Karasawa, T Yamamoto, A Kojo, M Onozuk. Soft-diet feeding decreases dopamine release and impairs aversion learning in Alzheimer model rats. Neuroscience letters. vol 439. issue 2. 2008-10-14. PMID:18514408. |
to examine the effects of soft-diet feeding on the dopaminergic system in a model rat for alzheimer's disease (ad), we measured dopamine release in the hippocampus using a microdialysis approach and assessed learning ability and memory using step-through passive avoidance tests. |
2008-10-14 |
2023-08-12 |
rat |
| Takeya Kitta, Machiko Matsumoto, Hiroshi Tanaka, Takahiko Mitsui, Mitsuhiro Yoshioka, Katsuya Nonomur. GABAergic mechanism mediated via D receptors in the rat periaqueductal gray participates in the micturition reflex: an in vivo microdialysis study. The European journal of neuroscience. vol 27. issue 12. 2008-10-09. PMID:18554296. |
the present study elucidated dynamic changes in dopamine (da), glutamate and gamma-aminobutyric acid (gaba) in the rat pag during the micturition reflex, with a focus on dopaminergic modulation using in vivo microdialysis combined with cystometrography. |
2008-10-09 |
2023-08-12 |
rat |
| Shyamal H Mehta, John C Morgan, Kapil D Seth. Neuroimaging and transcranial ultrasonography in Parkinson's disease. Current neurology and neuroscience reports. vol 8. issue 4. 2008-10-09. PMID:18590613. |
parkinson's disease is a progressive, widespread, neurodegenerative disease in which the involvement of the dopaminergic neurons of the substantia nigra results in significant dopamine depletion in the striatum. |
2008-10-09 |
2023-08-12 |
Not clear |
| Lucia Carvelli, Randy D Blakely, Louis J DeFelic. Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 37. 2008-10-09. PMID:18768815. |
dopamine transporter/syntaxin 1a interactions regulate transporter channel activity and dopaminergic synaptic transmission. |
2008-10-09 |
2023-08-12 |
caenorhabditis_elegans |
| Kathryn T O'Leary, Neeraja Parameswaran, Louisa C Johnston, J Michael McIntosh, Donato A Di Monte, Maryka Qui. Paraquat exposure reduces nicotinic receptor-evoked dopamine release in monkey striatum. The Journal of pharmacology and experimental therapeutics. vol 327. issue 1. 2008-10-08. PMID:18606871. |
the functional studies showed that paraquat exposure attenuated dopamine (da) release evoked by alpha3/alpha6beta2(*) (nachr that is composed of the alpha3 or alpha6 subunits, and beta2; the asterisk indicates the possible presence of additional subunits) nachrs, a subtype present only on striatal dopaminergic terminals, with no decline in release mediated by alpha4beta2(*) (nachr containing alpha4 and beta2 subunits, but not alpha3 or alpha6) nachrs, present on both da terminals and striatal neurons. |
2008-10-08 |
2023-08-12 |
mouse |
| Michael J Frank, Lauren Kon. Learning to avoid in older age. Psychology and aging. vol 23. issue 2. 2008-10-07. PMID:18573012. |
the dopamine hypothesis of aging suggests that a monotonic dopaminergic decline accounts for many of the changes found in cognitive aging. |
2008-10-07 |
2023-08-12 |
Not clear |
| Nobuhisa Ohtsuka, Morris F Tansky, Hui Kuang, Saïd Kourrich, Mark J Thomas, John L R Rubenstein, Marc Ekker, Susan E Leeman, Joe Z Tsie. Functional disturbances in the striatum by region-specific ablation of NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 35. 2008-10-06. PMID:18728179. |
to study the role of nmda receptors in dopamine signaling of the striatum, the brain area that receives glutamatergic inputs from various cortical areas and most dopaminergic inputs, we generated striatum-specific nmda receptor-deficient mice. |
2008-10-06 |
2023-08-12 |
mouse |
| Jing Ji, Dean E Dluze. Sex differences in striatal dopaminergic function within heterozygous mutant dopamine transporter knock-out mice. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 6. 2008-10-03. PMID:18197357. |
sex differences in striatal dopaminergic function within heterozygous mutant dopamine transporter knock-out mice. |
2008-10-03 |
2023-08-12 |
mouse |
| M Fedi, S F Berkovic, I E Scheffer, G O'Keefe, C Marini, R Mulligan, S Gong, H Tochon-Danguy, D C Reuten. Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy. Neurology. vol 71. issue 11. 2008-10-03. PMID:18685138. |
as activation of presynaptic nicotinic receptors augments the release of dopamine in the striatum and the prefrontal regions, we tested the hypothesis that that the alpha4-ser248phe mutation affects dopaminergic transmission. |
2008-10-03 |
2023-08-12 |
Not clear |