| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antti Pertovaara, Hong We. Dual influence of the striatum on neuropathic hypersensitivity. Pain. vol 137. issue 1. 2008-12-01. PMID:17870240. |
this antihypersensitivity effect is predominantly ipsilateral and it descends via parallel dopaminergic and serotoninergic pathways to act on spinal dopamine d2 and 5-ht(1a) receptors, respectively. |
2008-12-01 |
2023-08-12 |
rat |
| Antti Pertovaara, Hong We. Dual influence of the striatum on neuropathic hypersensitivity. Pain. vol 137. issue 1. 2008-12-01. PMID:17870240. |
involvement of striatal dopamine d2 receptors in the noradrenergic pain inhibitory circuitry may explain why disorders causing hypofunction of the striatal dopaminergic system, such as in parkinson's disease, have been associated with pain. |
2008-12-01 |
2023-08-12 |
rat |
| Alessandro Martorana, Alessandro Stefani, Maria Giuseppina Palmieri, Zaira Esposito, Giorgio Bernardi, Giuseppe Sancesario, Mariangela Pierantozz. L-dopa modulates motor cortex excitability in Alzheimer's disease patients. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 9. 2008-12-01. PMID:18594753. |
these results indicate a possible role of dopamine in modulating ad cortical excitability, thus suggesting an interaction between dopaminergic ascending pathways and endogenous intracortical transmitters. |
2008-12-01 |
2023-08-12 |
human |
| Oh Bin Kwon, Daniel Paredes, Carmen M Gonzalez, Jörg Neddens, Luis Hernandez, Detlef Vullhorst, Andres Buonann. Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 40. 2008-11-28. PMID:18832154. |
the novel functional link between nrg-1, dopamine, and glutamate has important implications for understanding how imbalances in neuregulin-erbb signaling can impinge on dopaminergic and glutamatergic function, neurotransmitter pathways associated with schizophrenia. |
2008-11-28 |
2023-08-12 |
mouse |
| J Glowinsk. [Biosynthesis, storage and release of dopamine at the level of the dopaminergic nigro-neostriatal system]. Archives italiennes de biologie. vol 111. issue 3-4. 2008-11-25. PMID:18847048. |
[biosynthesis, storage and release of dopamine at the level of the dopaminergic nigro-neostriatal system]. |
2008-11-25 |
2023-08-12 |
Not clear |
| Galina P Kirillova, Rebecca J Hrutkay, Michael R Shurin, Galina V Shurin, Irina L Tourkova, Michael M Vanyuko. Dopamine receptors in human lymphocytes: radioligand binding and quantitative RT-PCR assays. Journal of neuroscience methods. vol 174. issue 2. 2008-11-18. PMID:18721826. |
analysis of dopamine receptors (dr) in lymphocytes of the human peripheral blood mononuclear cell (pbmc) fraction is an attractive tool for evaluation of functional properties of dopaminergic function underlying variation in complex psychological/psychopathological traits. |
2008-11-18 |
2023-08-12 |
human |
| Ken-Ichi Fujimot. [Pathological gambling and Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo. vol 60. issue 9. 2008-11-18. PMID:18807938. |
in addition to pg other impulse control behaviors and punding (repetitive stereotyped behavior) are recognized as components of the dopamine dysregulation syndrome (dds), which is characterized by the compulsive use of dopaminergic medications, including levodopa and subcutaneous apomorphine. |
2008-11-18 |
2023-08-12 |
Not clear |
| Jonathan Moss, J Paul Bola. A dopaminergic axon lattice in the striatum and its relationship with cortical and thalamic terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 44. 2008-11-18. PMID:18971464. |
we conclude that (1) thalamostriatal synapses are in a position to be influenced by released dopamine to a similar degree as corticostriatal synapses are and (2) these associations arise from a nonselective dopaminergic axon lattice. |
2008-11-18 |
2023-08-12 |
rat |
| Nobutaka Sakae, Nobuyuki Yamasaki, Kiyoyuki Kitaichi, Takaichi Fukuda, Mitsunori Yamada, Hiroo Yoshikawa, Takato Hiranita, Yoshiki Tatsumi, Jun-ichi Kira, Tsuneyuki Yamamoto, Tsuyoshi Miyakawa, Keiichi I Nakayam. Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Human molecular genetics. vol 17. issue 20. 2008-11-12. PMID:18647754. |
in vivo microdialysis revealed that the methamphetamine-induced release of dopamine in the nucleus accumbens was exaggerated in the mutant mice, suggesting that enhanced mesolimbic dopaminergic transmission contributes to their hyperactivity phenotype. |
2008-11-12 |
2023-08-12 |
mouse |
| Gerardo Florez, Pilar Saiz, Paz Garcia-Portilla, Sandra Alvarez, Luis Nogueíras, Blanca Morales, Victoria Alvarez, Eliecer Coto, Julio Bobe. Association between the Stin2 VNTR polymorphism of the serotonin transporter gene and treatment outcome in alcohol-dependent patients. Alcohol and alcoholism (Oxford, Oxfordshire). vol 43. issue 5. 2008-11-07. PMID:18552399. |
the aim of this study was to investigate the potential association between functional polymorphisms of dopaminergic [dopamine receptor d2 (drd2), dopamine receptor d3 (drd3) and dopamine transporter (slc6a3)] and serotonergic [serotonin 2a receptor (htr2a) and serotonin transporter (slc6a4)] genes and treatment outcome in alcohol-dependent patients. |
2008-11-07 |
2023-08-12 |
Not clear |
| Carla Neri, Carla Ghelardini, Bethany Sotak, Richard D Palmiter, Massimo Guarna, George Stefano, Enrica Bianch. Dopamine is necessary to endogenous morphine formation in mammalian brain in vivo. Journal of neurochemistry. vol 106. issue 6. 2008-11-07. PMID:18643791. |
in this study, we used mice that cannot make dopamine due to a genetic deletion of tyrosine hydroxylase specifically in dopaminergic neurons, to test the hypothesis that endogenous dopamine is necessary to endogenous morphine formation in vivo in mammalian brain. |
2008-11-07 |
2023-08-12 |
mouse |
| Regina C C Kubrusly, Rogerio Panizzutti, Patricia F Gardino, Bernardo Stutz, Ricardo A M Reis, Ana Lucia M Ventura, Maria Christina F de Mello, Fernando G de Mell. Expression of functional dopaminergic phenotype in purified cultured Müller cells from vertebrate retina. Neurochemistry international. vol 53. issue 3-4. 2008-11-06. PMID:18582514. |
dopamine release occurs via a transporter-mediated process and can activate dopaminergic d(1) receptors expressed by the glia population. |
2008-11-06 |
2023-08-12 |
mouse |
| Paolo Calabresi, Massimiliano Di Filipp. ACh/dopamine crosstalk in motor control and reward: a crucial role for alpha 6-containing nicotinic receptors? Neuron. vol 60. issue 1. 2008-11-06. PMID:18940582. |
find that alpha6-containing nicotinic acetylcholine receptors might selectively activate mesolimbic and mesostriatal dopaminergic neurons, enhancing striatal dopamine release and its behavioral consequences. |
2008-11-06 |
2023-08-12 |
Not clear |
| Lisa A Briand, Shelly B Flagel, Philip Seeman, Terry E Robinso. Cocaine self-administration produces a persistent increase in dopamine D2 High receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 8. 2008-11-05. PMID:18284941. |
we suggest, therefore, that cocaine addicts and animals previously treated with cocaine may be hyper-responsive to dopaminergic drugs in part because an increase in d2 high receptors results in dopamine supersensitivity. |
2008-11-05 |
2023-08-12 |
human |
| Kevin C F Fone, M Veronica Porkes. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neuroscience and biobehavioral reviews. vol 32. issue 6. 2008-11-05. PMID:18423591. |
these alterations are associated with hyperfunction of mesolimbic dopaminergic systems, enhanced presynaptic dopamine (da) and serotonergic (5-ht) function in the nucleus accumbens (nacc), hypofunction of mesocortical da and attenuated 5-ht function in the prefrontal cortex and hippocampus. |
2008-11-05 |
2023-08-12 |
rat |
| Julie Blanchet, Fanny Longpré, Geneviève Bureau, Marc Morissette, Thérèse DiPaolo, Gilles Bronchti, Maria-Grazia Martinol. Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 5. 2008-11-05. PMID:18471948. |
administration of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to c57bl/6 mice targets nigrostriatal dopaminergic neurons, leading to cell death and striatal dopamine (da) depletion. |
2008-11-05 |
2023-08-12 |
mouse |
| Haroldo Evangelista Vargas, Clarissa Severino Gama, Ana Cristina Andreazza, Dalton Medeiros, Laura Stertz, Gabriel Fries, Joana Palha, Keila Maria Cereser, Michael Berk, Flavio Kapczinski, Paulo Silva Belmonte-de-Abre. Decreased serum neurotrophin 3 in chronically medicated schizophrenic males. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18572319. |
nt3 has a central role in the early neuronal development; enhancing the survival of dopaminergic neurons, suggesting possible involvement in the physiopathology of dopamine related neuropsychiatric disorders such as sz. |
2008-11-05 |
2023-08-12 |
Not clear |
| Supriti Samantaray, Swapan K Ray, Naren L Bani. Calpain as a potential therapeutic target in Parkinson's disease. CNS & neurological disorders drug targets. vol 7. issue 3. 2008-11-05. PMID:18673214. |
however, central dopaminergic replenishment therapeutic strategy with l-3,4-dihydroxyphenylalanine (l-dopa), the precursor for dopamine synthesis, does not fully rescue these cells in sn or improve motor function. |
2008-11-05 |
2023-08-12 |
Not clear |
| Mauro Porta, Marco Sassi, Mario Cavallazzi, Maurizio Fornari, Arianna Brambilla, Domenico Servell. Tourette's syndrome and role of tetrabenazine: review and personal experience. Clinical drug investigation. vol 28. issue 7. 2008-11-04. PMID:18544005. |
the suggestion of a central role of dopamine in the aetiology of ts has been made on the basis of experimental studies, evidence from neuroimaging studies and the therapeutic response patients with ts have to agents that antagonize or interfere with putative dopaminergic pathways. |
2008-11-04 |
2023-08-12 |
Not clear |
| E Stice, S Spoor, C Bohon, D M Smal. Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele. Science (New York, N.Y.). vol 322. issue 5900. 2008-11-03. PMID:18927395. |
the dorsal striatum plays a role in consummatory food reward, and striatal dopamine receptors are reduced in obese individuals, relative to lean individuals, which suggests that the striatum and dopaminergic signaling in the striatum may contribute to the development of obesity. |
2008-11-03 |
2023-08-12 |
Not clear |