| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Polina Petkova-Kirova, Angelina Rakovska, Galina Zaekova, Chiara Ballini, Laura Della Corte, Radomir Radomirov, Anikó Vágvölgy. Stimulation by neurotensin of dopamine and 5-hydroxytryptamine (5-HT) release from rat prefrontal cortex: possible role of NTR1 receptors in neuropsychiatric disorders. Neurochemistry international. vol 53. issue 6-8. 2009-03-09. PMID:18835308. |
the modulation of cortical dopaminergic and serotonergic neurotransmissions by neurotensin (nt) was studied by measuring the release of dopamine (da) and 5-hydroxytryptamine (5-ht) from the prefrontal cortex (pfc) of freely moving rats. |
2009-03-09 |
2023-08-12 |
rat |
| Leslie A Sombers, Manna Beyene, Regina M Carelli, R Mark Wightma. Synaptic overflow of dopamine in the nucleus accumbens arises from neuronal activity in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 6. 2009-03-06. PMID:19211880. |
here we show that dopamine transients are evoked by neural activity in the ventral tegmental area (vta), a brain region containing dopaminergic cell bodies. |
2009-03-06 |
2023-08-12 |
rat |
| O M Kharchilava, L A Valeev. [Effects of surgical ovariectomy on dopamine receptors of the heart and brain]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. issue 4. 2009-03-03. PMID:19202617. |
changes in density and affinity of dopamine receptors in the heart and brain of rats after surgical ovariectomy evidence for involvement of dopaminergic system in pathogenesis of menopausal syndrome. |
2009-03-03 |
2023-08-12 |
rat |
| J E de Leeuw van Weenen, L Hu, K Jansen-Van Zelm, M G de Vries, J T Tamsma, J A Romijn, H Pij. Four weeks high fat feeding induces insulin resistance without affecting dopamine release or gene expression patterns in the hypothalamus of C57Bl6 mice. Brain research. vol 1250. 2009-02-27. PMID:19028458. |
the high fat diet did not alter dopamine release in the dorsomedial hypothalamus of fed or fasted mice or the dopaminergic response to refeeding. |
2009-02-27 |
2023-08-12 |
mouse |
| Zhi Dong Zhou, Sze Yen Kerk, Gao Gao Xiong, Tit Meng Li. Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells. Journal of neurochemistry. vol 108. issue 3. 2009-02-24. PMID:19046408. |
dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human a53t mutant alpha-synuclein in dopaminergic pc12 cells. |
2009-02-24 |
2023-08-12 |
human |
| Tatiana Sorkina, Toni L Richards, Anjali Rao, Nancy R Zahniser, Alexander Sorki. Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 5. 2009-02-24. PMID:19193883. |
the plasma membrane dopamine transporter (dat) takes extracellular dopamine back up into dopaminergic neurons. |
2009-02-24 |
2023-08-12 |
human |
| Roshan Cools, Michael J Frank, Sasha E Gibbs, Asako Miyakawa, William Jagust, Mark D'Esposit. Striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 5. 2009-02-24. PMID:19193900. |
striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration. |
2009-02-24 |
2023-08-12 |
human |
| Roshan Cools, Michael J Frank, Sasha E Gibbs, Asako Miyakawa, William Jagust, Mark D'Esposit. Striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 5. 2009-02-24. PMID:19193900. |
in addition, baseline dopamine synthesis predicted the direction of dopaminergic drug effects. |
2009-02-24 |
2023-08-12 |
human |
| Xuebo Liu, Naruomi Yamada, Wakako Maruyama, Toshihiko Osaw. Formation of dopamine adducts derived from brain polyunsaturated fatty acids: mechanism for Parkinson disease. The Journal of biological chemistry. vol 283. issue 50. 2009-02-19. PMID:18922792. |
furthermore, hexanoyl dopamine (hed), an arachidonic acid-derived adduct, caused severe cytotoxicity in human dopaminergic neuroblastoma sh-sy5y cells, whereas the other adducts were only slightly affected. |
2009-02-19 |
2023-08-12 |
mouse |
| Elizabeth M Azzato, Lindsay M Morton, Andrew W Bergen, Sophia S Wang, Nilanjan Chatterjee, Paul Kvale, Meredith Yeager, Richard B Hayes, Stephen J Chanock, Neil E Caporas. SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. BMC medical genetics. vol 10. 2009-02-16. PMID:19183461. |
to investigate the contribution of the dopamine transporter to dopaminergic reward-related behaviors and anthropometry, we evaluated associations between polymorphisms at the dopamine transporter gene(slc6a3) and body mass index (bmi), among participants in the prostate, lung, colorectal and ovarian (plco) cancer screening trial. |
2009-02-16 |
2023-08-12 |
human |
| Tracey A Baskerville, Alison J Dougla. Interactions between dopamine and oxytocin in the control of sexual behaviour. Progress in brain research. vol 170. 2009-02-13. PMID:18655889. |
however, while we show that oxytocin neurons express dopamine receptors, other evidence on whether dopaminergic activation of pvn oxytocin cells involves a direct and/or indirect mechanism is inconclusive and further evidence is required to establish whether the two systems interact synergistically or sequentially in the regulation of penile erection. |
2009-02-13 |
2023-08-12 |
Not clear |
| Peter Jenne. Preventing and controlling dyskinesia in Parkinson's disease--a view of current knowledge and future opportunities. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781676. |
loss of tonic stimulation of striatal dopamine receptors in pd and its replacement by pulsatile dopaminergic stimulation using short acting drugs has been proposed as leading to the abnormalities that cause dyskinesia induction. |
2009-02-13 |
2023-08-12 |
Not clear |
| Peter Jenne. Preventing and controlling dyskinesia in Parkinson's disease--a view of current knowledge and future opportunities. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781676. |
as a consequence, the concept of continuous dopaminergic stimulation (cds) was introduced to explain why longer acting dopamine agonists do not produce the same intensity of dyskinesia. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yoland Smith, Rosa Villalb. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781680. |
degeneration of the nigrostriatal dopaminergic system is the characteristic neuropathological feature of parkinson's disease and therapy is primarily based on a dopamine replacement strategy. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yoland Smith, Rosa Villalb. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Movement disorders : official journal of the Movement Disorder Society. vol 23 Suppl 3. 2009-02-13. PMID:18781680. |
although the striatum remains the main functional target of dopamine, it is now appreciated that there is dopaminergic innervation of the pallidum, subthalamic nucleus, and substantia nigra. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yazhou Li, TracyAnn Perry, Mark S Kindy, Brandon K Harvey, David Tweedie, Harold W Holloway, Kathleen Powers, Hui Shen, Josephine M Egan, Kumar Sambamurti, Arnold Brossi, Debomoy K Lahiri, Mark P Mattson, Barry J Hoffer, Yun Wang, Nigel H Grei. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 4. 2009-02-13. PMID:19164583. |
ex-4 treatment also protected dopaminergic neurons against degeneration, preserved dopamine levels, and improved motor function in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) mouse model of parkinson's disease (pd). |
2009-02-13 |
2023-08-12 |
mouse |
| Valentina Ghisi, Amy J Ramsey, Bernard Masri, Raul R Gainetdinov, Marc G Caron, Ali Salahpou. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular signalling. vol 21. issue 1. 2009-02-06. PMID:18929645. |
the aim of this study was to examine the effect of this reduction in dopaminergic tone on postsynaptic responses mediated by dopamine receptors. |
2009-02-06 |
2023-08-12 |
mouse |
| Roger J Gillespie, Samantha J Bamford, Ruth Botting, Mike Comer, Sarah Denny, Suneel Gaur, Michael Griffin, Allan M Jordan, Anthony R Knight, Joanne Lerpiniere, Stefania Leonardi, Sean Lightowler, Steven McAteer, Angela Merrett, Anil Misra, Antony Padfield, Mark Reece, Mona Saadi, Daniel L Selwood, Gemma C Stratton, Dominic Surry, Richard Todd, Xin Tong, Vicki Ruston, Rebecca Upton, Scott M Weis. Antagonists of the human A(2A) adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo[4,5-d]pyrimidines. Journal of medicinal chemistry. vol 52. issue 1. 2009-02-06. PMID:19072055. |
this is thought to occur, at least in part, by increasing the sensitivity of the dopaminergic neurons to the residual, depleted levels of striatal dopamine. |
2009-02-06 |
2023-08-12 |
human |
| A Vinuela, P J Hallett, C Reske-Nielsen, M Patterson, T D Sotnikova, M G Caron, R R Gainetdinov, O Isacso. Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON L-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease. Brain : a journal of neurology. vol 131. issue Pt 12. 2009-02-02. PMID:18988638. |
to address this issue we transplanted foetal dopaminergic neurons from mice lacking the dopamine transporter (datko) or from wild-type mice, into a rat model of parkinson's disease and l-dopa-induced dyskinesias. |
2009-02-02 |
2023-08-12 |
mouse |
| David Crockford, Jeremy Quickfall, Shawn Currie, Sarah Furtado, Oksana Suchowersky, Nady El-Guebal. Prevalence of problem and pathological gambling in Parkinson's disease. Journal of gambling studies. vol 24. issue 4. 2009-01-30. PMID:18561000. |
pathological gambling (pg) has been identified in patients with parkinson's disease (pd) treated with dopamine agonists suggesting that dysregulation of brain dopaminergic activity may contribute to the development of gambling problems. |
2009-01-30 |
2023-08-12 |
human |