| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H K Kleitz-Nelson, C A Cornil, J Balthazart, G F Bal. Differential effects of central injections of D1 and D2 receptor agonists and antagonists on male sexual behavior in Japanese quail. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20597974. |
finally, the regulation of male sexual behavior by centrally infused dopaminergic compounds in a species lacking an intromittent organ suggested that dopamine action on male sexual behavior does not simply reflect the modulation of genital reflexes due to general arousal, but relates to the central control of sexual motivation. |
2011-01-13 |
2023-08-12 |
Not clear |
| Clotilde Mannoury la Cour, Marie-Josèphe Salles, Valérie Pasteau, Mark J Milla. Signaling pathways leading to phosphorylation of Akt and GSK-3β by activation of cloned human and rat cerebral D₂and D₃ receptors. Molecular pharmacology. vol 79. issue 1. 2011-01-13. PMID:20952497. |
although dopamine (da) regulates the serine/threonine kinase akt and its downstream substrate glycogen synthase kinase-3β (gsk-3β), the direct influence of dopaminergic receptors remains poorly characterized. |
2011-01-13 |
2023-08-12 |
human |
| Catrin Wernicke, Julian Hellmann, Ulrich Finckh, Hans Rommelspache. Chronic ethanol exposure changes dopamine D2 receptor splicing during retinoic acid-induced differentiation of human SH-SY5Y cells. Pharmacological reports : PR. vol 62. issue 4. 2011-01-12. PMID:20885005. |
the dopamine d2 receptor (drd2) and the dopamine transporter (dat) are decisively involved in dopaminergic signaling. |
2011-01-12 |
2023-08-12 |
human |
| Diego García-Borreguero, Anne-Marie William. Dopaminergic augmentation of restless legs syndrome. Sleep medicine reviews. vol 14. issue 5. 2011-01-11. PMID:20219397. |
as the primary neural and molecular substrates underlying idiopathic rls are not known, the pathophysiology of augmentation remains unclear, however there are several hypotheses that concern the role of dopaminergic hyperstimulation, of iron deficiency, the genetic component, the effect of a reduction in responsiveness of tubero-infundibular dopamine receptors, and the role of chronobiotic mechanisms. |
2011-01-11 |
2023-08-12 |
Not clear |
| Hideaki Kobayashi, Hiroshi Ujike, Nakao Iwata, Toshiya Inada, Mitsuhiko Yamada, Yoshimoto Sekine, Naohisa Uchimura, Masaomi Iyo, Norio Ozaki, Masanari Itokawa, Ichiro Sor. The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population. Behavioral and brain functions : BBF. vol 6. 2011-01-11. PMID:20799992. |
several lines of evidence suggest that the dopaminergic nervous system contributes to methamphetamine (meth) dependence, and there is increasing evidence of antagonistic interactions between dopamine and adenosine receptors. |
2011-01-11 |
2023-08-12 |
Not clear |
| Jie W. Double target concept for smoking cessation. Acta pharmacologica Sinica. vol 31. issue 9. 2011-01-04. PMID:20711220. |
through the nachrs in brain reward circuits, nicotine alters dopaminergic (da) neuronal function in the ventral tegmental area (vta) and increases dopamine release from vta to nuclear accumbens (na), which leads to nicotine reward, tolerance and dependence. |
2011-01-04 |
2023-08-12 |
Not clear |
| Blanca Rubí, Pierre Maechle. Minireview: new roles for peripheral dopamine on metabolic control and tumor growth: let's seek the balance. Endocrinology. vol 151. issue 12. 2011-01-04. PMID:21047943. |
peripheral and central dopamine systems are sensitive to environmental stress, such as a high-fat diet, suggesting a basis of covariance of peripheral and central actions of dopaminergic agents. |
2011-01-04 |
2023-08-12 |
Not clear |
| Blanca Rubí, Pierre Maechle. Minireview: new roles for peripheral dopamine on metabolic control and tumor growth: let's seek the balance. Endocrinology. vol 151. issue 12. 2011-01-04. PMID:21047943. |
delineation of peripheral and central dopaminergic mechanisms would facilitate targeted and safer use of drugs modulating dopamine action. |
2011-01-04 |
2023-08-12 |
Not clear |
| Douglas S Lehrer, Bradley T Christian, Cemil Kirbas, Meicheng Chiang, Shawn Sidhu, Holly Short, Binquan Wang, Bingzhi Shi, King-Wai Chu, Brian Merrill, Monte S Buchsbau. 18F-fallypride binding potential in patients with schizophrenia compared to healthy controls. Schizophrenia research. vol 122. issue 1-3. 2010-12-30. PMID:20655709. |
molecular imaging of dopaminergic parameters has contributed to the dopamine hypothesis of schizophrenia, expanding our understanding of pathophysiology, clinical phenomenology and treatment. |
2010-12-30 |
2023-08-12 |
Not clear |
| Juliano C Capra, Mauricio P Cunha, Daniele G Machado, Andrea D E Zomkowski, Beatriz G Mendes, Adair Roberto S Santos, Moacir G Pizzolatti, Ana Lúcia S Rodrigue. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599906. |
the pretreatment of mice with ketanserin (5mg/kg, i.p., a preferential 5-ht(2a) receptor antagonist), prazosin (1mg/kg, i.p., an alpha(1)-adrenoceptor antagonist), yohimbine (1mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), haloperidol (0.2mg/kg, i.p., a dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) or sulpiride (50mg/kg, i.p., a dopamine d(2) receptor antagonist), but not way100635 (0.1mg/kg, s.c., a selective 5-ht(1a) receptor antagonist) prevented the antidepressant-like effect of scopoletin (10mg/kg, p.o.) |
2010-12-28 |
2023-08-12 |
mouse |
| Juliano C Capra, Mauricio P Cunha, Daniele G Machado, Andrea D E Zomkowski, Beatriz G Mendes, Adair Roberto S Santos, Moacir G Pizzolatti, Ana Lúcia S Rodrigue. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599906. |
the results indicate that its antidepressant-like effect is dependent on the serotonergic (5-ht(2a) receptors), noradrenergic (alpha(1)- and alpha(2)-adrenoceptors) and dopaminergic (dopamine d(1) and d(2) receptors) systems. |
2010-12-28 |
2023-08-12 |
mouse |
| Alexandre Benedetto, Catherine Au, Daiana Silva Avila, Dejan Milatovic, Michael Aschne. Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans. PLoS genetics. vol 6. issue 8. 2010-12-28. PMID:20865164. |
extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a bli-3-dependent manner in caenorhabditis elegans. |
2010-12-28 |
2023-08-12 |
caenorhabditis_elegans |
| Jihyun Kim, Soojeong Lee, Syungkyun Ko, Jeongsil Kim-H. dGIPC is required for the locomotive activity and longevity in Drosophila. Biochemical and biophysical research communications. vol 402. issue 3. 2010-12-28. PMID:21029723. |
our findings, together with those obtained from vertebrate models, suggest that drosophiladgipc acts in the adult central nervous system and may be required to regulate the trafficking of dopamine receptors needed for proper functioning of dopaminergic neurons. |
2010-12-28 |
2023-08-12 |
drosophila_melanogaster |
| Thomas V Wiecki, Michael J Fran. Neurocomputational models of motor and cognitive deficits in Parkinson's disease. Progress in brain research. vol 183. 2010-12-27. PMID:20696325. |
the loss of dopaminergic neurons innervating the striatum in pd, and the well-established role of dopamine (da) in reinforcement learning (rl), enable neural network models of the basal ganglia (bg) to derive concrete and testable predictions. |
2010-12-27 |
2023-08-12 |
Not clear |
| Paul R A Stokes, Alice Egerton, Ben Watson, Alistair Reid, Gerome Breen, Anne Lingford-Hughes, David J Nutt, Mitul A Meht. Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge. NeuroImage. vol 52. issue 4. 2010-12-17. PMID:20451621. |
in man, striatal dopamine release can be indexed using [11c]-raclopride positron emission tomography (pet), and recent reports suggest that cortical [11c]-raclopride binding may also be sensitive to dopaminergic challenges. |
2010-12-17 |
2023-08-12 |
human |
| Roberto Cilia, Ji Hyun Ko, Sang Soo Cho, Thilo van Eimeren, Giorgio Marotta, Giovanna Pellecchia, Gianni Pezzoli, Angelo Antonini, Antonio P Strafell. Reduced dopamine transporter density in the ventral striatum of patients with Parkinson's disease and pathological gambling. Neurobiology of disease. vol 39. issue 1. 2010-12-14. PMID:20338240. |
using striatal dopamine transporter (dat) with single photon emission tomography we assessed presynaptic dopaminergic function in 8 pd patients with pg, 21 matched pd control subjects, and 14 healthy subjects. |
2010-12-14 |
2023-08-12 |
human |
| Ulderico Freo, Antonio Merico, Mario Ermani, Carlo Or. Chronic treatment with fluoxetine decreases cerebral metabolic responses to the 5-HT1A agonist 8-hydroxy-2(di-N-propylamino)tetralin and increases those to the 5-HT2A/2C agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane and to the dopaminergic agonist apomorphine. Brain research. vol 1335. 2010-12-13. PMID:20381465. |
to assess functional changes occurring in the 5-ht and dopaminergic systems, we investigated the effects of 5-ht(1a) agonist 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat), of the 5-ht(2a/2c) agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) and of the dopamine d(1/2) agonist apomorphine (apo) on behavior and on regional cerebral metabolic rates for glucose (rcmrglc) in rats pretreated for 3weeks with saline or fluoxetine (8mg/kg/day). |
2010-12-13 |
2023-08-12 |
rat |
| A Knapman, J-M Heinzmann, F Holsboer, R Landgraf, C Toum. Modeling psychotic and cognitive symptoms of affective disorders: Disrupted latent inhibition and reversal learning deficits in highly stress reactive mice. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20451634. |
furthermore, as the dopaminergic system is involved in both li and reversal learning, the dopamine 1 receptor (d1r), dopamine 2 receptor (d2r) and dopamine transporter (dat) mrna expression levels were assessed in relevant brain areas of these animals. |
2010-12-13 |
2023-08-12 |
mouse |
| Michael A Nitsche, Katia Monte-Silva, Min-Fang Kuo, Walter Paulu. Dopaminergic impact on cortical excitability in humans. Reviews in the neurosciences. vol 21. issue 4. 2010-12-10. PMID:21086761. |
the neurotransmitter has a non-linear dose-dependent effect on cortical excitability and activity, which depends on spontaneous activity, dopamine concentration, and dopaminergic sub-receptors, amongst others. |
2010-12-10 |
2023-08-12 |
human |
| Daniel P Eisenberg, Philip D Kohn, Erica B Baller, Joel A Bronstein, Joseph C Masdeu, Karen F Berma. Seasonal effects on human striatal presynaptic dopamine synthesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 44. 2010-12-08. PMID:21048126. |
past studies in rodents have demonstrated circannual variation in central dopaminergic activity as well as a host of compelling interactions between melatonin--a scotoperiod-responsive neurohormone closely tied to seasonal adaptation--and dopamine in the striatum and in midbrain neuronal populations with striatal projections. |
2010-12-08 |
2023-08-12 |
human |