| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Escubedo, S Abad, I Torres, J Camarasa, D Pubil. Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity. Neurochemistry international. vol 58. issue 1. 2011-03-31. PMID:21074589. |
we conclude that meda could protect against the serotonergic lesion induced by mdma but potentiate the dopaminergic lesion as a result of the persistent blockade of the dopamine transporter induced this metabolite. |
2011-03-31 |
2023-08-12 |
mouse |
| S Kumar, G Ho, Y Zhang, L Zhu. In vivo imaging of retinal gliosis: a platform for diagnosis of PD and Screening of anti-PD compounds. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2010. 2011-03-30. PMID:21095732. |
it is characterized by the depletion of mesenchephalic dopaminergic (da) neurons in the substantia nigra pars compacta (snpc) and striatal dopamine. |
2011-03-30 |
2023-08-12 |
mouse |
| Stefano Pallanti, Alessandra Borgheresi, Ilenia Pampaloni, Fabio Giovannelli, Silvia Bernardi, Andrea Cantisani, Gaetano Zaccara, Massimo Cincott. Motor cortex excitability correlates with novelty seeking in social anxiety: a transcranial magnetic stimulation investigation. Journal of neurology. vol 257. issue 8. 2011-03-24. PMID:20352252. |
the correlation between reduced striatal dopaminergic (da) function, sad motor symptoms and the high occurrence of sad in patients with parkinson's disease (pd), suggests a link between sad and movement diseases caused by dopamine dysfunction. |
2011-03-24 |
2023-08-12 |
human |
| Nikolai Kholodilov, Sang Ryong Kim, Olga Yarygina, Tatyana Kareva, Jin Whan Cho, Amy Baohan, Robert E Burk. Glial cell line-derived neurotrophic factor receptor-α1 expressed in striatum in trans regulates development and injury response of dopamine neurons of the substantia nigra. Journal of neurochemistry. vol 116. issue 4. 2011-03-22. PMID:21133924. |
to determine whether post-synaptic expression of gfrα1 in striatum in trans has effects on the development or adult responses to injury of dopamine neurons, we have created transgenic mice in which gfrα1 expression is selectively increased in striatum and other forebrain targets of the dopaminergic projection. |
2011-03-22 |
2023-08-12 |
mouse |
| Yukihiro Noda, Akihiro Mouri, Yu Ando, Yukari Waki, Shin-Nosuke Yamada, Akira Yoshimi, Kiyofumi Yamada, Norio Ozaki, Dayong Wang, Toshitaka Nabeshim. Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems. The international journal of neuropsychopharmacology. vol 13. issue 10. 2011-03-18. PMID:20219155. |
these results suggest that the ameliorating effect of galantamine on meth-induced memory impairment is associated with indirect activation of dopamine d1 receptor-erk1/2 following augmentation with dopaminergic neurotransmission in the pfc through the allosteric activation of nachrs. |
2011-03-18 |
2023-08-12 |
mouse |
| Lauren A O'Connell, Miles R Fontenot, Hans A Hofman. Characterization of the dopaminergic system in the brain of an African cichlid fish, Astatotilapia burtoni. The Journal of comparative neurology. vol 519. issue 1. 2011-03-14. PMID:21120929. |
to understand better where dopamine acts to regulate social behavior in this species, we have determined the distribution of putative dopaminergic cells and fibers (by tyrosine hydroxylase immunohistochemistry) and dopamine receptors (by in situ hybridization for the d(1a) and d(2) dopamine receptor subtypes) throughout the forebrain and part of the mesencephalon of a. burtoni. |
2011-03-14 |
2023-08-12 |
Not clear |
| Lauren A O'Connell, Miles R Fontenot, Hans A Hofman. Characterization of the dopaminergic system in the brain of an African cichlid fish, Astatotilapia burtoni. The Journal of comparative neurology. vol 519. issue 1. 2011-03-14. PMID:21120929. |
these results significantly extend our understanding of the distribution of the dopaminergic system in the teleost brain and suggest a conserved role of dopamine in modulating behavior across vertebrates. |
2011-03-14 |
2023-08-12 |
Not clear |
| Maarit Hellman, Johan Peränen, Mart Saarma, Perttu Perm. 1H, 13C and 15N resonance assignments of the human mesencephalic astrocyte-derived neurotrophic factor. Biomolecular NMR assignments. vol 4. issue 2. 2011-03-04. PMID:20617400. |
recently discovered ntfs mesencephalic astrocyte-derived neurotrophic factor (manf) and conserved dopamine neurotrophic factor (cdnf) most efficiently protect and repair the dopaminergic neurons in the animal 6-ohda models of pd. |
2011-03-04 |
2023-08-12 |
human |
| Tom H Johnston, Philippe Huot, Susan H Fox, James D Wakefield, Kristine A Sykes, Wilmin P Bartolini, G Todd Milne, James P Pearson, Jonathan M Brotchi. Fatty acid amide hydrolase (FAAH) inhibition reduces L-3,4-dihydroxyphenylalanine-induced hyperactivity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned non-human primate model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics. vol 336. issue 2. 2011-03-03. PMID:20966038. |
dopaminergic therapies remain the most efficacious symptomatic treatments for parkinson's disease (pd) but are associated with motor complications, including dyskinesia, and nonmotor complications, such as psychosis, impulse control disorders (icd), and dopamine dysregulation syndrome (dds). |
2011-03-03 |
2023-08-12 |
marmoset |
| F M Gómez, J E Ortega, I Horrillo, J J Mean. Relationship between non-functional masticatory activity and central dopamine in stressed rats. Journal of oral rehabilitation. vol 37. issue 11. 2011-03-03. PMID:21039747. |
to clarify the relationship between central dopaminergic activity and stress-induced parafunctional masticatory behaviour, using microdialysis in vivo, we assessed the changes in extracellular dopamine concentrations in both prefrontal cortex and striatum of rats subjected to a mild tail pinch. |
2011-03-03 |
2023-08-12 |
rat |
| Marios Politi. Dyskinesias after neural transplantation in Parkinson's disease: what do we know and what is next? BMC medicine. vol 8. 2011-03-01. PMID:21126348. |
it has been suggested that graft-induced dyskinesias could be related to fiber outgrowth from the graft causing increased dopamine release, that could be related to the failure of grafts to restore a precise distribution of dopaminergic synaptic contacts on host neurons or may also be induced by inflammatory and immune responses around the graft. |
2011-03-01 |
2023-08-12 |
human |
| Athanasios Metaxas, Alexis Bailey, Maria Flavia Barbano, Lola Galeote, Rafael Maldonado, Ian Kitche. Differential region-specific regulation of α4β2* nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice. Addiction biology. vol 15. issue 4. 2011-02-28. PMID:20731631. |
cytisine-sensitive [(125)i]epibatidine binding, [³h]sch23390, [³h]raclopride and [³h]mazindol were used to label nachrs with α4β2* subtype properties, d1 and d2 dopaminergic receptors, and dopamine transporters, respectively. |
2011-02-28 |
2023-08-12 |
mouse |
| E Prieto, J A Micó, J J Meana, S Majada. Neurobiological bases of quetiapine antidepresant effect in the bipolar disorder. Actas espanolas de psiquiatria. vol 38. issue 1. 2011-02-28. PMID:20931407. |
regarding the dopaminergic pathway, quetiapine leads to an increasing of prefrontal dopamine release by antagonism of5-ht2a receptors, partial agonist of 5-ht1a and antagonism of a2 adrenoceptors. |
2011-02-28 |
2023-08-12 |
Not clear |
| Yunmin Ding, Lisa Won, Jonathan P Britt, Sean Austin O Lim, Daniel S McGehee, Un Jung Kan. Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 2. 2011-02-24. PMID:21187382. |
using two pd models, the traditional 6-hydroxydopamine toxic lesion and a genetic model with nigrostriatal dopaminergic deficits, we found that acute dopamine challenge induces erk activation in medium spiny neurons in denervated striatum. |
2011-02-24 |
2023-08-12 |
mouse |
| Yasuhiko Izumi, Toshiaki Kume, Akinori Akaik. [Regulation of dopaminergic neuronal death by endogenous dopamine and proteasome activity]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 131. issue 1. 2011-02-24. PMID:21212609. |
[regulation of dopaminergic neuronal death by endogenous dopamine and proteasome activity]. |
2011-02-24 |
2023-08-12 |
Not clear |
| Yasuhiko Izumi, Toshiaki Kume, Akinori Akaik. [Regulation of dopaminergic neuronal death by endogenous dopamine and proteasome activity]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 131. issue 1. 2011-02-24. PMID:21212609. |
although endogenous dopamine itself could serve as a vulnerability factor for dopaminergic neurons, the mechanism by which dopamine contributes to dopaminergic neuronal death remains unknown. |
2011-02-24 |
2023-08-12 |
Not clear |
| Yasuhiko Izumi, Toshiaki Kume, Akinori Akaik. [Regulation of dopaminergic neuronal death by endogenous dopamine and proteasome activity]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 131. issue 1. 2011-02-24. PMID:21212609. |
here we provide an overview of the roles of endogenous dopamine and proteasome activity in dopaminergic cell death. |
2011-02-24 |
2023-08-12 |
Not clear |
| Emily K Bloesch, Richard A Abram. Visuomotor binding in older adults. Brain and cognition. vol 74. issue 3. 2011-02-23. PMID:20810199. |
this process appears to be controlled by the dopaminergic system in the prefrontal cortex, an area that is known to decrease in volume and dopamine functioning in older adults. |
2011-02-23 |
2023-08-12 |
Not clear |
| Ashiwel S Undie. Pharmacology of signaling induced by dopamine D(1)-like receptor activation. Pharmacology & therapeutics. vol 128. issue 1. 2011-02-22. PMID:20547182. |
dopamine d(1)-like receptors consisting of d(1) and d(5) subtypes are intimately implicated in dopaminergic regulation of fundamental neurophysiologic processes such as mood, motivation, cognitive function, and motor activity. |
2011-02-22 |
2023-08-12 |
Not clear |
| Ashiwel S Undie. Pharmacology of signaling induced by dopamine D(1)-like receptor activation. Pharmacology & therapeutics. vol 128. issue 1. 2011-02-22. PMID:20547182. |
it is expected that significant advances in understanding of dopamine neurobiology will emerge from current and anticipated studies directed at uncovering the molecular mechanisms of d(5) coupling to phosphoinositide signaling, the structural features that might enhance pharmacological selectivity for d(5) versus d(1) subtypes, the mechanism by which dopamine may modulate phosphoinositide synthesis, the contributions of the various responsive signal mediators to d(1) or d(5) interactions with d(2)-like receptors, and the spectrum of dopaminergic functions that may be attributed to each receptor subtype and signaling pathway. |
2011-02-22 |
2023-08-12 |
Not clear |