| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V G Khaindrava, E A Kozina, V G Kucherianu, G N Kryzhanovskiĭ, V S Kudrin, P D Klodt, E V Bocharov, K S Raevskiĭ, M V Ugriumo. [Modeling of preclinical and early clinical stages of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 7. 2011-05-02. PMID:20639856. |
in the striatum, the region of dopaminergic axon projection, the content of dopamine and number of dopaminergic axons decreased by 57% and 59%, respectively, i.e. |
2011-05-02 |
2023-08-12 |
mouse |
| V G Khaindrava, E A Kozina, V G Kucherianu, G N Kryzhanovskiĭ, V S Kudrin, P D Klodt, E V Bocharov, K S Raevskiĭ, M V Ugriumo. [Modeling of preclinical and early clinical stages of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 7. 2011-05-02. PMID:20639856. |
in the striatum, the dopamine content and number of dopaminergic axons decreased by 75% and 68%, respectively. |
2011-05-02 |
2023-08-12 |
mouse |
| V G Khaindrava, E A Kozina, V G Kucherianu, G N Kryzhanovskiĭ, V S Kudrin, P D Klodt, E V Bocharov, K S Raevskiĭ, M V Ugriumo. [Modeling of preclinical and early clinical stages of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 7. 2011-05-02. PMID:20639856. |
in the substantia nigra, there were no changes in dopamine content but the number of dopaminergic neurons decreased by 43%. |
2011-05-02 |
2023-08-12 |
mouse |
| Lauren A O'Connell, Bryan J Matthews, Michael J Ryan, Hans A Hofman. Characterization of the dopamine system in the brain of the túngara frog, Physalaemus pustulosus. Brain, behavior and evolution. vol 76. issue 3-4. 2011-05-02. PMID:21099197. |
in order to better understand where dopamine acts to regulate social decisions in this species, we have determined the distribution of putative dopaminergic cells (using tyrosine hydroxylase immunohistochemistry) and cells receptive to dopaminergic signaling (using darpp-32 immunohistochemistry) throughout the brain of p. pustulosus. |
2011-05-02 |
2023-08-12 |
Not clear |
| Lingyun Li, Xiaoxia Wang, Xifeng Fei, Liping Xia, Zhenghong Qin, Zhongqin Lian. Parkinson's disease involves autophagy and abnormal distribution of cathepsin L. Neuroscience letters. vol 489. issue 1. 2011-05-02. PMID:21134415. |
when pretreated with 3-methyladenine (3-ma), dopaminergic neurons were protected from cell death induced by 6-ohda, associated with the suppression of lc3 and cathepsin l. our results demonstrate that activation of autophagy and abnormal distribution of cathepsin l may be responsible for dopamine neuron death, involved in the pathogenic cascade event for the development of parkinson's disease. |
2011-05-02 |
2023-08-12 |
rat |
| Katalin Nagy, Bernadett Marko, Gabriella Zsilla, Peter Matyus, Katalin Pallagi, Geza Szabo, Zsolt Juranyi, Jozsef Barkoczy, Gyorgy Levay, Laszlo G Harsin. Alterations in brain extracellular dopamine and glycine levels following combined administration of the glycine transporter type-1 inhibitor Org-24461 and risperidone. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:20725779. |
the therapeutic efficacy of all atypical antipsychotics is explained in part by antagonism of the dopaminergic neurotransmission, mainly by blockade of d(2) dopamine receptors. |
2011-04-28 |
2023-08-12 |
rat |
| Pierre-Olivier Fernagut, Qin Li, Sandra Dovero, Piu Chan, Tao Wu, Paula Ravenscroft, Michael Hill, Zhenwen Chen, Erwan Bezar. Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. PloS one. vol 5. issue 11. 2011-04-27. PMID:21124922. |
several clinical trials comparing dopamine agonists to l-dopa or early vs. late l-dopa have revealed differences between clinical assessment and imaging of the presynaptic dopaminergic system, hence questioning the comparability of these measures as neuroprotection outcome variables. |
2011-04-27 |
2023-08-12 |
monkey |
| Karl Strecker, Florian Wegner, Swen Hesse, Georg-Alexander Becker, Marianne Patt, Philipp M Meyer, Donald Lobsien, Johannes Schwarz, Osama Sabr. Preserved serotonin transporter binding in de novo Parkinson's disease: negative correlation with the dopamine transporter. Journal of neurology. vol 258. issue 1. 2011-04-25. PMID:20644949. |
since the loss of dopaminergic neurons is the pathologic hallmark of pd and sert might be associated with psychiatric co-morbidity, we further sought to correlate sert availability with the availability of dopamine transporter (dat) and depressive or motor symptoms in early pd. |
2011-04-25 |
2023-08-12 |
human |
| Jessica E van Schijndel, Martine van Zweeden, Karen M J van Loo, Luuk J Lubbers, Gerard J Pesman, Fred C G J Sweep, Gerard J M Marten. Dopamine susceptibility of APO-SUS rats is not per se coupled to HPA-axis activity. Physiology & behavior. vol 102. issue 2. 2011-04-25. PMID:21034754. |
thus, in the apo-sus/apo-unsus rat model the level of hpa-axis activity is not necessarily causally linked to dopamine responsiveness, implying that a hyperactive hpa-axis is not a prerequisite for a high dopaminergic response. |
2011-04-25 |
2023-08-12 |
rat |
| Sujira Mukda, Oranich Vimolratana, Piyarat Govitrapon. Melatonin attenuates the amphetamine-induced decrease in vesicular monoamine transporter-2 expression in postnatal rat striatum. Neuroscience letters. vol 488. issue 2. 2011-04-25. PMID:21078367. |
the vesicular monoamine transporter-2 (vmat-2) is responsible for packaging intraneuronal dopamine into synaptic vesicles in preparation for synaptic release and is a critical regulator of cytoplasmic dopamine levels and dopaminergic function. |
2011-04-25 |
2023-08-12 |
rat |
| Y H Dang, Y Zhao, B Xing, X J Zhao, F Q Huo, J S Tang, C L Qu, T Che. The role of dopamine receptors in ventrolateral orbital cortex-evoked anti-nociception in a rat model of neuropathic pain. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20599592. |
these results suggest that the dopaminergic system is involved in mediating vlo-induced anti-hypersensitivity, activation of d(2)-like dopamine receptors, and inhibition of d(1)-like receptors resulting in anti-hypersensitivity. |
2011-04-18 |
2023-08-12 |
rat |
| M Beyene, R M Carelli, R M Wightma. Cue-evoked dopamine release in the nucleus accumbens shell tracks reinforcer magnitude during intracranial self-stimulation. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600644. |
these data support the proposed role of nac dopamine in the facilitation of reward-seeking and provide unique insight into factors influencing the plasticity of dopaminergic signaling during behavior. |
2011-04-18 |
2023-08-12 |
rat |
| Claudia Nesti, Carla Pardini, Serena Barachini, Delfo D'Alessandro, Gabriele Siciliano, Luigi Murri, Mario Petrini, Francesca Vaglin. Human dental pulp stem cells protect mouse dopaminergic neurons against MPP+ or rotenone. Brain research. vol 1367. 2011-04-15. PMID:20854799. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the progressive death of substantia nigra dopaminergic neurons that results in a regional loss of striatal dopamine (da) levels. |
2011-04-15 |
2023-08-12 |
mouse |
| Wataru Taniguchi, Terumasa Nakatsuka, Nobuyuki Miyazaki, Hiroshi Yamada, Daisuke Takeda, Tsugumi Fujita, Eiichi Kumamoto, Munehito Yoshid. In vivo patch-clamp analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord. Pain. vol 152. issue 1. 2011-04-14. PMID:21050660. |
to elucidate the mechanisms of antinociception mediated by the dopaminergic descending pathway in the spinal cord, we investigated the actions of dopamine (da) on substantia gelatinosa (sg) neurons by in vivo whole-cell patch-clamp methods. |
2011-04-14 |
2023-08-12 |
Not clear |
| Hamid Y Qureshi, Hemant K Paude. Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro. The Journal of biological chemistry. vol 286. issue 7. 2011-04-11. PMID:21127069. |
in parkinson disease (pd) brain, a progressive loss of dopaminergic neurons leads to dopamine depletion in the striatum and reduced motor function. |
2011-04-11 |
2023-08-12 |
mouse |
| Kei Yamamoto, Jori O Ruuskanen, Mario F Wullimann, Philippe Vernie. Differential expression of dopaminergic cell markers in the adult zebrafish forebrain. The Journal of comparative neurology. vol 519. issue 3. 2011-04-11. PMID:21192085. |
although the simultaneous presence of tyrosine hydroxylase (th), aromatic amino acid decarboxylase (aadc), dopamine transporter (dat), and vesicular monoamine transporter 2 (vmat2) is considered as a phenotypic signature of dopamine (da) neurons, it has been suggested that they are not uniformly expressed in all dopaminergic brain nuclei. |
2011-04-11 |
2023-08-12 |
zebrafish |
| Yuko Kuroda, Nobutaka Motohashi, Hiroshi Ito, Shigeo Ito, Akihiro Takano, Hidehiko Takahashi, Toru Nishikawa, Tetsuya Suhar. Chronic repetitive transcranial magnetic stimulation failed to change dopamine synthesis rate: preliminary L-[β-11C]DOPA positron emission tomography study in patients with depression. Psychiatry and clinical neurosciences. vol 64. issue 6. 2011-04-07. PMID:21155169. |
we have examined the effects of repetitive transcranial magnetic stimulation (rtms) on central dopaminergic function in patients with depression using positron emission tomography with l-[β-11c]dopa, a ligand to assess the rate of endogenous dopamine synthesis. |
2011-04-07 |
2023-08-12 |
Not clear |
| A Vonaparti, E Lyris, I Panderi, M Koupparis, C Georgakopoulo. Direct injection horse-urine analysis for the quantification and confirmation of threshold substances for doping control. IV. Determination of 3-methoxytyramine by hydrophilic interaction liquid chromatography/quadrupole time-of-flight mass spectrometry. Drug testing and analysis. vol 1. issue 8. 2011-04-05. PMID:20355216. |
urinary 3-methoxytyramine is used as an indicator of dopaminergic manipulation resulting from dopamine or levodopa administration and is prohibited with a urinary threshold of 4 microg ml(-1) (free and conjugated). |
2011-04-05 |
2023-08-12 |
Not clear |
| Xinxin Yang, Baohua Chen. Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity. Journal of molecular neuroscience : MN. vol 42. issue 2. 2011-04-04. PMID:20333481. |
the main clinical symptom of pd is motor dysfunction derived from the loss of dopaminergic neurons in the substantia nigra (sn) and dopamine content in the striatum subsequently. |
2011-04-04 |
2023-08-12 |
mouse |
| Xinxin Yang, Baohua Chen. Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity. Journal of molecular neuroscience : MN. vol 42. issue 2. 2011-04-04. PMID:20333481. |
the change of dopamine was very similar to dopaminergic neurons in the sn. |
2011-04-04 |
2023-08-12 |
mouse |