| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasuhiko Izumi, Masayuki Ezumi, Yuki Takada-Takatori, Akinori Akaike, Toshiaki Kum. Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. Toxicological sciences : an official journal of the Society of Toxicology. vol 139. issue 2. 2014-12-29. PMID:24743698. |
endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. |
2014-12-29 |
2023-08-13 |
mouse |
| Yasuhiko Izumi, Masayuki Ezumi, Yuki Takada-Takatori, Akinori Akaike, Toshiaki Kum. Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. Toxicological sciences : an official journal of the Society of Toxicology. vol 139. issue 2. 2014-12-29. PMID:24743698. |
here, we report a contribution of endogenous dopamine to paraquat-induced dopaminergic cell death. |
2014-12-29 |
2023-08-13 |
mouse |
| Yasuhiko Izumi, Masayuki Ezumi, Yuki Takada-Takatori, Akinori Akaike, Toshiaki Kum. Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. Toxicological sciences : an official journal of the Society of Toxicology. vol 139. issue 2. 2014-12-29. PMID:24743698. |
a decline in intracellular dopamine content achieved by inhibiting tyrosine hydroxylase (th), an enzyme for dopamine synthesis, conferred resistance to paraquat toxicity on dopaminergic cells. |
2014-12-29 |
2023-08-13 |
mouse |
| Yasuhiko Izumi, Masayuki Ezumi, Yuki Takada-Takatori, Akinori Akaike, Toshiaki Kum. Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death. Toxicological sciences : an official journal of the Society of Toxicology. vol 139. issue 2. 2014-12-29. PMID:24743698. |
these results suggest that the elevation of cytosolic dopamine induced by paraquat participates in the vulnerability of dopaminergic cells to delayed toxicity through the formation of quinoproteins. |
2014-12-29 |
2023-08-13 |
mouse |
| Marc T Pisansky, Robert J Wickham, Jianjun Su, Stephanie Fretham, Li-Lian Yuan, Mu Sun, Jonathan C Gewirtz, Michael K Georgief. Iron deficiency with or without anemia impairs prepulse inhibition of the startle reflex. Hippocampus. vol 23. issue 10. 2014-12-23. PMID:23733517. |
iron deficiency (id) during early life causes long-lasting detrimental cognitive sequelae, many of which are linked to alterations in hippocampus function, dopamine synthesis, and the modulation of dopaminergic circuitry by the hippocampus. |
2014-12-23 |
2023-08-12 |
mouse |
| Keon Sung Shin, Ting Ting Zhao, Hyun Sook Choi, Bang Yeon Hwang, Chong Kil Lee, Myung Koo Le. Effects of gypenosides on anxiety disorders in MPTP-lesioned mouse model of Parkinson's disease. Brain research. vol 1567. 2014-12-23. PMID:24747613. |
these results suggest that gps (50mg/kg) and gp-ex (50mg/kg) showed anxiolytic effects on affective disorders and protective effects on dopaminergic neurons by modulating the brain levels of dopamine and serotonin in the mptp-lesioned mouse model of pd with or without l-dopa treatment. |
2014-12-23 |
2023-08-13 |
mouse |
| Subhamita Maitra, Kanyakumarika Sarkar, Paramita Ghosh, Arijit Karmakar, Animesh Bhattacharjee, Swagata Sinha, Kanchan Mukhopadhya. Potential contribution of dopaminergic gene variants in ADHD core traits and co-morbidity: a study on eastern Indian probands. Cellular and molecular neurobiology. vol 34. issue 4. 2014-12-22. PMID:24585059. |
association of dopaminergic genes, mainly receptors and transporters, with attention deficit hyperactivity disorder (adhd) has been investigated throughout the world due to the importance of dopamine (da) in various physiological functions including attention, cognition and motor activity, traits. |
2014-12-22 |
2023-08-12 |
Not clear |
| Julie Péron, Didier Grandjean, Sophie Drapier, Marc Véri. Effect of dopamine therapy on nonverbal affect burst recognition in Parkinson's disease. PloS one. vol 9. issue 3. 2014-12-22. PMID:24651759. |
although previous studies of emotional prosody recognition in pd have reported evidence of impairment, none of them compared pd patients at different stages of the disease, or on and off dopamine replacement therapy, making it difficult to determine whether their impairment was due to general cognitive deterioration or to a more specific dopaminergic deficit. |
2014-12-22 |
2023-08-12 |
Not clear |
| Reza J Rasoulpour, Claire Terry, Matthew J LeBaron, Kenneth Stebbins, Robert G Ellis-Hutchings, Richard Billingto. Mode-of-action and human relevance framework analysis for rat Leydig cell tumors associated with sulfoxaflor. Critical reviews in toxicology. vol 44 Suppl 2. 2014-12-22. PMID:24832552. |
analysis sulfoxaflor data suggested a hormone-based dopamine enhancement moa causing the lct effect through: 1) increased neuronal dopamine release via specific dopaminergic neuron-based nicotinic acetylcholine receptor (nachr) agonism, leading to 2) decreased serum prolactin (prl) levels, 3) downregulation of luteinizing hormone receptor (lhr) gene expression in leydig cells, 4) transient decreases in serum testosterone, 5) increased serum lh levels, and 6) promotion of lcts. |
2014-12-22 |
2023-08-13 |
human |
| Ramón Sotomayor-Zárate, Pablo Jara, Patricio Araos, Raúl Vinet, Gabriel Quiroz, Georgina M Renard, Pedro Espinosa, Claudio Hurtado-Guzmán, Pablo R Moya, Patricio Iturriaga-Vásquez, Katia Gysling, Miguel Reyes-Parad. Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction. Basic & clinical pharmacology & toxicology. vol 114. issue 5. 2014-12-18. PMID:24314229. |
in this work, we show that similarly to mta, n,n-dimethyl-thioamphetamine has effects on the dopamine system, producing a significant increase in extracellular levels of dopamine (as measured by in vivo brain microdialysis) and locomotor activity, which is a behavioural measure of dopaminergic activation. |
2014-12-18 |
2023-08-12 |
Not clear |
| Alkisti Batzina, Christina Dalla, Aristeidis Tsopelakos, Zeta Papadopoulou-Daifoti, Nafsika Karakatsoul. Environmental enrichment induces changes in brain monoamine levels in gilthead seabream Sparus aurata. Physiology & behavior. vol 130. 2014-12-18. PMID:24680728. |
no differences were observed for dopamine metabolites or dopaminergic activity. |
2014-12-18 |
2023-08-12 |
Not clear |
| Iria G Dopeso-Reyes, Alberto J Rico, Elvira Roda, Salvador Sierra, Diego Pignataro, Maria Lanz, Diego Sucunza, Luis Chang-Azancot, Jose L Lancieg. Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques. Frontiers in neuroanatomy. vol 8. 2014-12-18. PMID:25520629. |
although a direct link between cb content and differential vulnerability of dopaminergic neurons has long been accepted, factors other than cb have also been suggested, particularly those related to the dopamine transporter. |
2014-12-18 |
2023-08-13 |
monkey |
| Erica L Unger, Laura E Bianco, Byron C Jones, Richard P Allen, Christopher J Earle. Low brain iron effects and reversibility on striatal dopamine dynamics. Experimental neurology. vol 261. 2014-12-17. PMID:24999026. |
iron deficiency (id) in rodents leads to decreased ventral midbrain (vmb) iron concentrations and to changes in the dopamine (da) system that mimic many of the dopaminergic changes seen in rls patient where low substantia nigra iron is a known pathology of the disease. |
2014-12-17 |
2023-08-13 |
rat |
| A P Athanasoulia, C Sievers, M Uhr, M Ising, G K Stalla, H J Schneide. The effect of the ANKK1/DRD2 Taq1A polymorphism on weight changes of dopaminergic treatment in prolactinomas. Pituitary. vol 17. issue 3. 2014-12-16. PMID:23740147. |
the presence of at least one a1 allele is linked to reduced brain dopaminergic activity due to reduced receptor binding and lower density of the dopamine 2 receptor. |
2014-12-16 |
2023-08-12 |
Not clear |
| A P Athanasoulia, C Sievers, M Uhr, M Ising, G K Stalla, H J Schneide. The effect of the ANKK1/DRD2 Taq1A polymorphism on weight changes of dopaminergic treatment in prolactinomas. Pituitary. vol 17. issue 3. 2014-12-16. PMID:23740147. |
we aimed at testing the hypothesis that the dopaminergic treatment in prolactinoma patients leads to sustained weight loss and that the presence of diminished weight loss response under dopamine agonists is associated with the minor a1 allele of taq1a.we included n = 44 patients (17 male and 27 female, 26 macroadenomas and 18 microadenomas) with prolactinomas treated with dopamine agonists. |
2014-12-16 |
2023-08-12 |
Not clear |
| Ginetta Collo, Laura Cavalleri, PierFranco Span. Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine. Frontiers in pharmacology. vol 5. 2014-12-16. PMID:25505416. |
structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of bdnf and dopamine. |
2014-12-16 |
2023-08-13 |
Not clear |
| Anton A H P Megens, Herman M R Hendrickx, Michel M A Mahieu, Annemie L Y Wellens, Peter de Boer, Greet Vanhoo. PDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathways. Pharmacology research & perspectives. vol 2. issue 4. 2014-12-16. PMID:25505601. |
while the effects of pde10ais on spontaneous and stimulated behavior have been extensively reported, the present study investigates their effects on suppressed behavior under various conditions of reduced dopaminergic neurotransmission: blockade of d1 receptors with sch-23390, blockade of d2 receptors with haloperidol, or depletion of dopamine with ro-4-1284 or reserpine. |
2014-12-16 |
2023-08-13 |
mouse |
| D Leo, L Mus, S Espinoza, M C Hoener, T D Sotnikova, R R Gainetdino. Taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of D2 dopamine autoreceptors. Neuropharmacology. vol 81. 2014-12-15. PMID:24565640. |
taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of d2 dopamine autoreceptors. |
2014-12-15 |
2023-08-12 |
mouse |
| Ping Liu, Liang Sun, Xu-Li Zhao, Peng Zhang, Xue-Mei Zhao, Jian Zhan. PAR2-mediated epigenetic upregulation of α-synuclein contributes to the pathogenesis of Parkinson׳s disease. Brain research. vol 1565. 2014-12-15. PMID:24747612. |
parkinson׳s disease (pd) is a common neurodegenerative disorder characterized by the selective degeneration of projecting dopaminergic neurons in the substantia nigra and diminished dopamine levels in the striatum. |
2014-12-15 |
2023-08-13 |
rat |
| Julia J Didonet, Judney C Cavalcante, Lisiane de S Souza, Miriam S M O Costa, Eunice André, Vanessa de P Soares-Rachetti, Remo Guerrini, Girolamo Calo', Elaine C Gaviol. Neuropeptide S counteracts 6-OHDA-induced motor deficits in mice. Behavioural brain research. vol 266. 2014-12-12. PMID:24613977. |
based on the close relationship between dopamine and parkinson disease (pd) and on the evidence that npsr are expressed on brain dopaminergic nuclei, the present study investigated the effects of nps in motor deficits induced by intracerebroventricular (icv) administration of the dopaminergic neurotoxin 6-ohda in the mouse rotarod test. |
2014-12-12 |
2023-08-12 |
mouse |