| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yao Lu, Nicolette Driscoll, Ilker Ozden, Zeyang Yu, Arto V Nurmikk. Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics. Neurophotonics. vol 2. issue 3. 2015-07-14. PMID:26171413. |
modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics. |
2015-07-14 |
2023-08-13 |
mouse |
| Donald G Grosset, Klaus Tatsch, Wolfgang H Oertel, Eduardo Tolosa, Nin Bajaj, Andreas Kupsch, John T O'Brien, John Seibyl, Zuzana Walker, Paul Sherwin, Chris Chen, Igor D Grache. Safety analysis of 10 clinical trials and for 13 years after first approval of ioflupane 123I injection (DaTscan). Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 8. 2015-07-13. PMID:24947061. |
ioflupane is an analog of cocaine that binds reversibly with high affinity to the dopamine transporter (dat) protein, a marker for presynaptic terminals in dopaminergic nigrostriatal neurons. |
2015-07-13 |
2023-08-13 |
human |
| K Brami-Cherrier, A Anzalone, M Ramos, I Forne, F Macciardi, A Imhof, E Borrell. Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits. Molecular psychiatry. vol 19. issue 11. 2015-07-13. PMID:25023144. |
we modeled a dysfunctional dopaminergic system using mice with targeted ablation of dopamine (da) d2 autoreceptors in mesencephalic dopaminergic neurons. |
2015-07-13 |
2023-08-13 |
mouse |
| Mats Julius Stensrud, Maja Puchades, Vidar Gunderse. GABA is localized in dopaminergic synaptic vesicles in the rodent striatum. Brain structure & function. vol 219. issue 6. 2015-07-07. PMID:23851655. |
our results suggest that gaba is exocytosed together with dopamine from dopaminergic nerve terminals in the caudo-putamen through vgat negative and vmat2 positive synaptic vesicles. |
2015-07-07 |
2023-08-12 |
Not clear |
| Pia Baldinger, Andreas Hahn, Markus Mitterhauser, Georg S Kranz, Marion Friedl, Wolfgang Wadsak, Christoph Kraus, Johanna Ungersböck, Annette Hartmann, Ina Giegling, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Impact of COMT genotype on serotonin-1A receptor binding investigated with PET. Brain structure & function. vol 219. issue 6. 2015-07-07. PMID:23928748. |
given the close interactions between serotonergic and dopaminergic neurotransmission, we investigated whether a common single-nucleotide-polymorphism of the catechol-o-methyltransferase (comt) gene (val158met or rs4680) coding for a key enzyme of the dopamine network that is associated with the pathogenesis of mood disorders and antidepressant treatment response, directly affects 5-ht1a receptor binding potential. |
2015-07-07 |
2023-08-12 |
human |
| Gabriela Pérez-Barrón, José Guillermo Avila-Acevedo, Ana María García-Bores, Sergio Montes, Sara García-Jiménez, Ismael León-Rivera, Moisés Rubio-Osornio, Antonio Monroy-Noyol. Neuroprotective effect of Buddleja cordata methanolic extract in the 1-methyl-4-phenylpyridinium Parkinson's disease rat model. Journal of natural medicines. vol 69. issue 1. 2015-07-02. PMID:25253176. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the irreversible loss of dopaminergic neurons in the nigrostriatal pathway with subsequent dopamine deficiency. |
2015-07-02 |
2023-08-13 |
rat |
| Marcella Nebbioso, Andrea Maria Plateroti, Bruna Pucci, Nicola Pescosolid. Role of the dopaminergic system in the development of myopia in children and adolescents. Journal of child neurology. vol 29. issue 12. 2015-06-29. PMID:24996871. |
an increase of the retinal levels of dopamine activates d1 and d2 dopaminergic receptors present throughout the retina, generating a signal that inhibits axial growth once the eye has reached emmetropization. |
2015-06-29 |
2023-08-13 |
Not clear |
| Marcella Nebbioso, Andrea Maria Plateroti, Bruna Pucci, Nicola Pescosolid. Role of the dopaminergic system in the development of myopia in children and adolescents. Journal of child neurology. vol 29. issue 12. 2015-06-29. PMID:24996871. |
considering the role of the dopaminergic system in the development of myopia (in children and adolescents) and the fact that phenylethylamine improves the consequences of a dopamine deficit, it would be interesting to study the effect of phenylethylamine on the regulation of axial growth, which represents the genesis of myopia. |
2015-06-29 |
2023-08-13 |
Not clear |
| Gaurav Patki, Fatin Atrooz, Isam Alkadhi, Naimesh Solanki, Samina Sali. High aggression in rats is associated with elevated stress, anxiety-like behavior, and altered catecholamine content in the brain. Neuroscience letters. vol 584. 2015-06-26. PMID:25450144. |
significant alterations in dopamine (da), norepinephrine (ne) and epinephrine (epi) were observed within the hippocampus, amygdala, and the prefrontal cortex, suggesting potential involvement of dopaminergic and noradrenergic systems in regulation of aggressive behaviors. |
2015-06-26 |
2023-08-13 |
rat |
| Nicholas I Cilz, Lalitha Kurada, Binqi Hu, Saobo Le. Dopaminergic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K⁺, and T-type Ca²⁺ channels. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 12. 2015-06-25. PMID:23843440. |
whereas the entorhinal cortex (ec) receives profuse dopaminergic innervations from the midbrain, the effects of dopamine (da) on γ-aminobutyric acid (gaba)ergic interneurons in this brain region have not been determined. |
2015-06-25 |
2023-08-12 |
Not clear |
| Anne Guillou, Nicola Romanò, Frederik Steyn, Karine Abitbol, Paul Le Tissier, Xavier Bonnefont, Chen Chen, Patrice Mollard, Agnès O Marti. Assessment of lactotroph axis functionality in mice: longitudinal monitoring of PRL secretion by ultrasensitive-ELISA. Endocrinology. vol 156. issue 5. 2015-06-25. PMID:25643154. |
we used a dopamine d2 receptor antagonist to relieve pituitary lactotrophs from the tuberoinfundibular dopaminergic inhibitory tone and demonstrate a d2-induced prl rise that can be used to evaluate both the secretory capacity of lactotrophs and the magnitude of the inhibitory tone on pituitary prl release. |
2015-06-25 |
2023-08-13 |
mouse |
| Mary Hongying Cheng, Ethan Block, Feizhuo Hu, Murat Can Cobanoglu, Alexander Sorkin, Ivet Baha. Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding. Frontiers in neurology. vol 6. 2015-06-24. PMID:26106364. |
human dopamine (da) transporter (hdat) regulates dopaminergic signaling in the central nervous system by maintaining the synaptic concentration of da at physiological levels, upon reuptake of da into presynaptic terminals. |
2015-06-24 |
2023-08-13 |
human |
| Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Nobutaka Hattori, Yuzuru Ima. PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila. PLoS genetics. vol 10. issue 6. 2015-06-23. PMID:24901221. |
manipulating the parkin phosphorylation status affected spontaneous dopamine release in the nerve terminals of dopaminergic neurons, the survivability of dopaminergic neurons and flight activity. |
2015-06-23 |
2023-08-13 |
drosophila_melanogaster |
| Motoko Iwashit. Phasic activation of ventral tegmental neurons increases response and pattern similarity in prefrontal cortex neurons. eLife. vol 3. 2015-06-23. PMID:25269147. |
phasic stimulation of dopaminergic neurons in the ventral tegmental area (vta) evoked prolonged ca(2+) transients, lasting ~30 s in layer 2/3 neurons of the pfc, which are regulated by a dopamine d1 receptor-dependent pathway. |
2015-06-23 |
2023-08-13 |
mouse |
| Lian Liu, Xijin Xu, Taofeek Akangbe Yekeen, Kun Lin, Weiqiu Li, Xia Hu. Assessment of association between the dopamine D2 receptor (DRD2) polymorphism and neurodevelopment of children exposed to lead. Environmental science and pollution research international. vol 22. issue 3. 2015-06-22. PMID:24469773. |
people pay more attention to dopaminergic neurotransmission, specifically dopamine receptor-2 (drd2) taq ia polymorphism, but no consensus has been reached. |
2015-06-22 |
2023-08-12 |
Not clear |
| Eleni Koutsilieri, Peter Riederer, Stefan du Plessis, Carsten Schelle. A short review on the relation between the dopamine transporter 10/10-repeat allele and ADHD: implications for HIV infection. Attention deficit and hyperactivity disorders. vol 6. issue 3. 2015-06-22. PMID:24696011. |
the dopamine transporter (dat) is a functional element of the dopaminergic synapse in the brain. |
2015-06-22 |
2023-08-13 |
human |
| Bingjie Xie, Fankai Lin, Lei Peng, Kaleem Ullah, Hanyan Wu, Hong Qing, Yulin Den. Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells. Acta biochimica et biophysica Sinica. vol 46. issue 11. 2015-06-22. PMID:25274329. |
this study suggests that ros caused by dopamine could contribute to the damage of dopaminergic neurons when mgo is increased during the course of diabetes. |
2015-06-22 |
2023-08-13 |
Not clear |
| Jefferson Menezes, Niége Alves, Sidnei Borges, Rafael Roehrs, Jociane de Carvalho Myskiw, Cristiane Regina Guerino Furini, Ivan Izquierdo, Pâmela B Mello-Carpe. Facilitation of fear extinction by novelty depends on dopamine acting on D1-subtype dopamine receptors in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 13. 2015-06-22. PMID:25775606. |
the novelty increased hippocampal dopamine levels and facilitated the extinction, which was inhibited by intrahippocampal protein synthesis inhibitor anisomysin, d1/d5 dopaminerdic antagonist sch23390, or pka inhibitor rp-camp and unaffected by pkc inhibitor gö6976; additionally, the hippocampal infusion of pka stimulator sp-camp reverts the effect of d1/d5 dopaminergic antagonist sch 23390, but the infusion of pkc stimulator pma does not. |
2015-06-22 |
2023-08-13 |
rat |
| Laura Tiemann, Henrik Heitmann, Enrico Schulz, Jochen Baumkötter, Markus Plone. Dopamine precursor depletion influences pain affect rather than pain sensation. PloS one. vol 9. issue 4. 2015-06-19. PMID:24760082. |
our finding of an influence of dopaminergic neurotransmission on affective but not sensory aspects of phasic pain suggests that analgesic effects of dopamine might be mediated by indirect effects on pain affect rather than by direct effects on ascending nociceptive signals. |
2015-06-19 |
2023-08-13 |
human |
| Candan Depboylu, Thomas W Rösler, Anderson de Andrade, Wolfgang H Oertel, Günter U Höglinge. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease. Journal of neurochemistry. vol 133. issue 4. 2015-06-18. PMID:25581060. |
however, nrg1β1 did not reverse mptp-induced decrease in dopamine levels and dopaminergic fibers in the striatum. |
2015-06-18 |
2023-08-13 |
mouse |