| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Schneider, A Kean, L DiStefan. GM1 ganglioside rescues substantia nigra pars compacta neurons and increases dopamine synthesis in residual nigrostriatal dopaminergic neurons in MPTP-treated mice. Journal of neuroscience research. vol 42. issue 1. 1996-01-30. PMID:8531220. |
gm1 ganglioside rescues substantia nigra pars compacta neurons and increases dopamine synthesis in residual nigrostriatal dopaminergic neurons in mptp-treated mice. |
1996-01-30 |
2023-08-12 |
mouse |
| S A Bayer, K V Wills, L C Triarhou, B Ghett. Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse. Experimental brain research. vol 105. issue 2. 1996-01-18. PMID:7498372. |
using tyrosine hydroxylase immunostaining combined with [3h]thymidine autoradiography, the time of origin of dopaminergic midbrain neurons in the retrorubral field, the substantia nigra pars compacta, the ventral tegmental area, and the interfascicular nucleus was determined in postnatal day 20 mice. |
1996-01-18 |
2023-08-12 |
mouse |
| E Roy, P Y Côté, L Grégoire, A Parent, P J Bédar. Mesencephalic grafts partially restore normal nigral dynorphin levels in 6-hydroxydopamine-lesioned rats treated chronically with L-dihydroxyphenylalanine. Neuroscience. vol 66. issue 2. 1995-12-07. PMID:7477882. |
however, only animals displaying heavy loss of dopaminergic neurons in the substantia nigra pars compacta showed significant changes of dynorphin levels in the substantia nigra following drug treatment. |
1995-12-07 |
2023-08-12 |
rat |
| T Wu, A Li, H L Wan. Neurotensin increases the cationic conductance of rat substantia nigra dopaminergic neurons through the inositol 1,4,5-trisphosphate-calcium pathway. Brain research. vol 683. issue 2. 1995-11-21. PMID:7552360. |
whole-cell patch-clamp recordings were used to investigate electrophysiological effects of neurotensin on acutely isolated dopaminergic (da) neurons of the rat substantia nigra pars compacta (snc). |
1995-11-21 |
2023-08-12 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644016. |
the distribution, density and cellular localization of gabaa receptors were studied using quantitative receptor autoradiography and 6-hydroxydopamine-induced degeneration of dopaminergic pars compacta neurons. |
1995-09-21 |
2023-08-12 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644016. |
the quantitative autoradiographic results showed that following quinolinic acid lesions in the striatum: (i) the greatest increase in the density of gabaa receptors occurred in the middle third (91% increase) of the pars reticulata; (ii) the receptors were mainly of the gabaa/bzi variety; and (iii) 6-hydroxydopamine-induced degeneration of the dopaminergic pars compacta neurons did not significantly affect the density of receptors, indicating that the increased receptor binding was mainly localized on non-dopaminergic pars reticulata neurons. |
1995-09-21 |
2023-08-12 |
rat |
| K K Yung, J P Bolam, A D Smith, S M Hersch, B J Ciliax, A I Leve. Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience. vol 65. issue 3. 1995-08-17. PMID:7609871. |
in contrast, d2 immunoreactivity but not d1 immunoreactivity was present in the dopaminergic neurons in the substantia nigra pars compacta and ventral pars reticulata. |
1995-08-17 |
2023-08-12 |
rat |
| O Vilela Filh. Thalamic ventrobasal stimulation for pain relief. Probable mechanisms, pathways and neurotransmitters. Arquivos de neuro-psiquiatria. vol 52. issue 4. 1995-08-16. PMID:7611957. |
the substantia nigra compacta projects excitatory dopaminergic axons to the striatal neurons (nigrostriatal pathway) with output to the globus pallidus internus and substantia nigra reticulata and so on. |
1995-08-16 |
2023-08-12 |
Not clear |
| B P Connop, R J Boegman, K Jhamandas, R J Beninge. Excitotoxic action of NMDA agonists on nigrostriatal dopaminergic neurons: modulation by inhibition of nitric oxide synthesis. Brain research. vol 676. issue 1. 1995-08-03. PMID:7540931. |
focal infusions of n-methyl-d-aspartate (nmda) or an endogenous nmda agonist, quinolinic acid (quin), into the substantia nigra pars compacta (snc) of adult sprague-dawley rats resulted in a dose-dependent depletion of ipsilateral striatal tyrosine hydroxylase (th) activity, a biochemical marker for dopaminergic neurons. |
1995-08-03 |
2023-08-12 |
rat |
| G Percheron, J Yelnik, C François, G Fénelon, B Talb. [Informational analysis of the basal ganglia related system]. Revue neurologique. vol 150. issue 8-9. 1995-06-22. PMID:7754299. |
distinguishable include regulators of the striatum (the dopaminergic pars compacta and the central complex of the thalamus or centre median-parafascicularis), regulators of the pallidonigrum (the subthalamic nucleus and the pedunculopontine complex) and internal regulators (at first the lateral nucleus of the pallidum). |
1995-06-22 |
2023-08-12 |
Not clear |
| N Marco, L Stinus, M Allard, M Le Moal, G Simonne. Neuropeptide FLFQRFamide receptors within the ventral mesenchephalon and dopaminergic terminal areas: localization and functional antiopioid involvement. Neuroscience. vol 64. issue 4. 1995-06-21. PMID:7753374. |
we show that: (i) unilateral lesions of dopaminergic perikarya produced by 6-hydroxydopamine did not affect either ipsi or contralateral neuropeptide flfqpqrfamide receptor density within the mesencephalon; (ii) unilateral lesions of intrinsic perikarya by ibotenic acid injected into the ventral tegmental area produced a significant reduction of neuropeptide flfqpqrfamide receptors (40%) in this region; (iii) in the substantia nigra pars compacta, ibotenic acid unilateral lesions did not affect the density of neuropeptide flfqpqrf-amide receptors; (iv) unilateral 6-hydroxydopamine or ibotenic acid lesions failed to affect neuropeptide flfqpqrfamide binding in the dopaminergic projection areas. |
1995-06-21 |
2023-08-12 |
Not clear |
| N Marco, L Stinus, M Allard, M Le Moal, G Simonne. Neuropeptide FLFQRFamide receptors within the ventral mesenchephalon and dopaminergic terminal areas: localization and functional antiopioid involvement. Neuroscience. vol 64. issue 4. 1995-06-21. PMID:7753374. |
these results suggest that, like opiate receptors, the neuropeptide flfqpqrfamide binding sites are not localized on dopaminergic neurons but are distributed on both soma of non dopaminergic cells in the ventral tegmental area and on fibers afferent to the ventral tegmental area and substantia nigra pars compacta. |
1995-06-21 |
2023-08-12 |
Not clear |
| V Bernard, C Legay, J Massoulie, B Bloc. Anatomical analysis of the neurons expressing the acetylcholinesterase gene in the rat brain, with special reference to the striatum. Neuroscience. vol 64. issue 4. 1995-06-21. PMID:7753391. |
all dopaminergic neurons of the substantia nigra pars compacta and ventral tegmental area were demonstrated to express the acetylcholinesterase gene. |
1995-06-21 |
2023-08-12 |
rat |
| J M Tepper, L P Martin, D R Anderso. GABAA receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 4. 1995-05-25. PMID:7722648. |
evidence from electrophysiological studies has suggested an inhibitory interaction between gabaergic neurons in substantia nigra pars reticulata and dopaminergic neurons in pars compacta. |
1995-05-25 |
2023-08-12 |
rat |
| E C Wolters, G Tissingh, P L Bergmans, M A Kuipe. Dopamine agonists in Parkinson's disease. Neurology. vol 45. issue 3 Suppl 3. 1995-05-15. PMID:7715794. |
the main pathologic hallmark of parkinson's disease is a degeneration of the dopaminergic cells in the substantia nigra, pars compacta and--to a lesser extent--in the ventral tegmental area. |
1995-05-15 |
2023-08-12 |
Not clear |
| A Mouatt-Prigent, Y Agid, E C Hirsc. Does the calcium binding protein calretinin protect dopaminergic neurons against degeneration in Parkinson's disease? Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704619. |
parkinson's disease (pd) is characterized by a heterogeneous loss of dopaminergic neurons in the human mesencephalon affecting mainly the substantia nigra pars compacta (snpc) and to a lesser extent the other dopaminergic cell groups. |
1995-05-10 |
2023-08-12 |
human |
| S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
the above findings are in accordance with recent electrophysiological studies suggesting the existence of sub-populations of nigrostriatal dopaminergic neurons, and indicate that the substantia nigra pars compacta is functionally compartmentalized. |
1995-02-17 |
2023-08-12 |
rat |
| S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
we conclude that the cholinergic input to the substantia nigra pars compacta could modulate the motor behavior through regulating the firing rate of nigrostriatal dopaminergic neurons and dopamine release in the neostriatum. |
1995-02-17 |
2023-08-12 |
rat |
| A Kastner, P Anglade, C Bounaix, P Damier, F Javoy-Agid, N Bromet, Y Agid, E C Hirsc. Immunohistochemical study of catechol-O-methyltransferase in the human mesostriatal system. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830891. |
the presence of catechol-o-methyltransferase in some dopaminergic neurons of the ventral tegmental area and substantia nigra pars lateralis suggests that methylation of dopamine may occur in these neurons, which may consequently be better protected against dopamine auto-oxidation than those of the substantia nigra pars compacta. |
1995-02-17 |
2023-08-12 |
human |
| M Hajós, S A Greenfiel. Synaptic connections between pars compacta and pars reticulata neurones: electrophysiological evidence for functional modules within the substantia nigra. Brain research. vol 660. issue 2. 1995-02-16. PMID:7820690. |
in contrast to the response of dopaminergic pars compacta neurones, pars reticulata neurones responded to stimulation over wide areas of substantia nigra, without any clear site-specific selectivity. |
1995-02-16 |
2023-08-12 |
Not clear |