| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Mraovitch, Y Calando, B Onteniente, M Peschanski, J Seyla. Cerebrovascular and metabolic uncoupling in the caudate-putamen following unilateral lesion of the mesencephalic dopaminergic neurons in the rat. Neuroscience letters. vol 157. issue 2. 1993-12-14. PMID:8233044. |
changes in local cerebral blood flow (lcbf) and local cerebral glucose utilization (lcgu) were assessed in dopaminergic primary target areas in the rat 6 weeks after unilateral lesion of dopaminergic neurons within the substantia nigra pars compacta (snc) and adjacent ventrotegmental area (vta) using 6-hydroxydopamine (6-ohda). |
1993-12-14 |
2023-08-12 |
rat |
| M Hajós, S A Greenfiel. Topographic heterogeneity of substantia nigra neurons: diversity in intrinsic membrane properties and synaptic inputs. Neuroscience. vol 55. issue 4. 1993-12-02. PMID:7901802. |
one class of nigral pars compacta cell showed the well-established electrophysiological characteristics of mesencephalic dopaminergic neurons, i.e. |
1993-12-02 |
2023-08-12 |
Not clear |
| K Ossowsk. Disturbances in neurotransmission processes in aging and age-related diseases. Polish journal of pharmacology. vol 45. issue 2. 1993-11-02. PMID:8401765. |
dopaminergic neurotransmission is impaired with age due to degeneration of the substantia nigra pars compacta neurons and reduction of the density of postsynaptic d1 and d2 dopamine receptors in the striatum. |
1993-11-02 |
2023-08-12 |
Not clear |
| R Srivastava, E Brouillet, M F Beal, E Storey, B T Hyma. Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss. Neurobiology of aging. vol 14. issue 4. 1993-10-04. PMID:8103573. |
when injected into the striatum, mpp+ is accumulated by dopaminergic nerve terminals and retrogradely transported to the substantia nigra pars compacta (snc) where it causes neuronal degeneration. |
1993-10-04 |
2023-08-12 |
rat |
| B D Pate, T Kawamata, T Yamada, E G McGeer, K A Hewitt, B J Snow, T J Ruth, D B Caln. Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices. Annals of neurology. vol 34. issue 3. 1993-09-30. PMID:8363350. |
after the animals were killed, the number and average size of dopaminergic neurons in the substantia nigra pars compacta were measured. |
1993-09-30 |
2023-08-12 |
monkey |
| P Anglade, S Tsuji, E C Hirsch, F Javoy-Agid, Y Agi. Ultrastructural relations between nigrostriatal dopaminergic neurons and cholinergic nerve endings in the human brain. Histology and histopathology. vol 8. issue 3. 1993-09-29. PMID:8102915. |
the connections between cholinergic nerve endings and nigrostriatal dopaminergic neurons were studied in the substantia nigra pars compacta of the human brain. |
1993-09-29 |
2023-08-12 |
human |
| P Zhang, P Damier, E C Hirsch, Y Agid, I Ceballos-Picot, P M Sinet, A Nicole, M Laurent, F Javoy-Agi. Preferential expression of superoxide dismutase messenger RNA in melanized neurons in human mesencephalon. Neuroscience. vol 55. issue 1. 1993-09-15. PMID:8350985. |
the copper-zinc-dependent superoxide dismutase messenger rna expression was studied at cellular level by in situ hybridization, using a 35s-labelled complementary dna probe homologous to human copper-zinc-dependent superoxide dismutase messenger rna, in the dopaminergic neuron-containing areas of the human mesencephalon (the substantia nigra pars compacta, ventral tegmental area, central gray substance and peri- and retrorubral region corresponding to catecholaminergic cell group a8). |
1993-09-15 |
2023-08-12 |
human |
| M Weiser, H Baker, T C Wessel, T H Jo. Differential spatial and temporal gene expression in response to axotomy and deafferentation following transection of the medial forebrain bundle. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 8. 1993-09-02. PMID:8101870. |
semi-quantitative in situ hybridization and immunohistochemical analysis demonstrated that the products of the immediate-early gene c-fos were induced postaxotomy in the noradrenergic neurons of the locus ceruleus (lc), but not in the dopaminergic neurons of the substantia nigra pars compacta (snc). |
1993-09-02 |
2023-08-12 |
Not clear |
| C L Liang, G P Kozlowski, D C Germa. Leucine5-enkephalin afferents to midbrain dopaminergic neurons: light and electron microscopic examination. The Journal of comparative neurology. vol 332. issue 3. 1993-08-13. PMID:8101195. |
leucine5-enkephalin stained fibers and terminals were observed with varying density in the retrorubral field (dopaminergic nucleus a8 region), substantia nigra pars compacta (dopaminergic nucleus a9 region), and ventral tegmental area and related nuclei (dopaminergic nucleus a10 region). |
1993-08-13 |
2023-08-12 |
mouse |
| T Hagg, S Varo. Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 13. 1993-08-06. PMID:8101002. |
we have investigated the neuroprotective effects of recombinant human ciliary neurotrophic factor (cntf) for injured dopaminergic neurons of the adult rat substantia nigra compacta. |
1993-08-06 |
2023-08-12 |
human |
| R Jenkins, R O'Shea, K L Thomas, S P Hun. c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8098512. |
we have examined the expression of immediate early genes in central neurons of the rat and now show that a 6-hydroxydopamine-induced axotomy of the dopaminergic nigrostriatal pathway results in a substantial increase in the levels of c-jun (but not c-fos) messenger rna and protein within neurons of the substantia nigra pars compacta. |
1993-06-11 |
2023-08-12 |
rat |
| P Gaspar, C W Heizmann, J H Kaa. Calbindin D-28K in the dopaminergic mesocortical projection of a monkey (Aotus trivirgatus). Brain research. vol 603. issue 1. 1993-04-16. PMID:8095839. |
numbers of mesocortical dopaminergic neurons in the dorsal substantia nigra compacta and in the ventral tegmental area also contain calbindin-d28k. |
1993-04-16 |
2023-08-12 |
monkey |
| A K Shetty, R C Burrows, D E Phillip. Alterations in neuronal development in the substantia nigra pars compacta following in utero ethanol exposure: immunohistochemical and Golgi studies. Neuroscience. vol 52. issue 2. 1993-04-15. PMID:8095703. |
the effects of gestational ethanol exposure on the development of dopaminergic neurons of substantia nigra pars compacta were investigated in the rat. |
1993-04-15 |
2023-08-12 |
rat |
| U Freo, G L Ricchieri, H W Holloway, T T Soncran. Time- and dose-dependent effects of the serotonergic agent quipazine on regional cerebral metabolism in rats. Brain research. vol 600. issue 2. 1993-03-23. PMID:8435750. |
quipazine increased rcmrglc in brain regions with high densities of 5-ht3 receptors (area postrema, olfactory tubercle, amygdala), in dopaminergic nuclei (substantia nigra pars compacta and pars reticulata) and terminal fields of their projections (zona incerta, subthalamic nucleus, preoptic magnocellular area, nucleus of facial nerve). |
1993-03-23 |
2023-08-12 |
rat |
| Y Masuo, H Wang, D Pélaprat, Z Q Chi, W Rostèn. Effect of brain lesions on [3H]ohmefentanyl binding site densities in the rat striatum and substantia nigra. Chemical & pharmaceutical bulletin. vol 40. issue 9. 1992-12-28. PMID:1332831. |
therefore, mu opioid receptors may be mainly located on intrinsic neurons in the striatum, dopaminergic cell bodies in the substantia nigra pars compacta and nerve terminals of striatal efferents in the substantia nigra pars reticulata. |
1992-12-28 |
2023-08-11 |
rat |
| T C Wessel, T H Jo. Parallel upregulation of catecholamine-synthesizing enzymes in rat brain and adrenal gland: effects of reserpine and correlation with immediate early gene expression. Brain research. Molecular brain research. vol 15. issue 3-4. 1992-12-14. PMID:1359376. |
the responses of the midbrain dopaminergic cells in the ventral tegmental area and substantia nigra compacta, locus ceruleus and adrenal gland were studied in three groups of animals receiving either no injection, vehicle injection or reserpine 10 mg/kg subcutaneously. |
1992-12-14 |
2023-08-11 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. The regional, cellular and subcellular localization of GABAA/benzodiazepine receptors in the substantia nigra of the rat. Neuroscience. vol 50. issue 2. 1992-12-01. PMID:1331862. |
quantitative autoradiographic studies showed that: (i) the pars reticulata contained mainly central type i receptors; (ii) the highest density of receptors was present in the caudal pars reticulata (200 +/- 38 fmol/mg) with successively lower densities of receptors in the middle (176 +/- 31 fmol/mg) and rostral (150 +/- 26 fmol/mg) levels of the pars reticulata; and (iii) the density of receptors in the pars reticulata was reduced by 34% following 6-hydroxydopamine-induced degeneration of dopaminergic pars compacta neurons. |
1992-12-01 |
2023-08-11 |
rat |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
the electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. |
1992-09-29 |
2023-08-11 |
Not clear |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
the dopaminergic neurons of the substantia nigra pars compacta and ventral tegmental area play a crucial role in regulating movement and cognition respectively. |
1992-09-29 |
2023-08-11 |
Not clear |
| M Hajós, S Greenfiel. Differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511329. |
segregation of the pars compacta from the pars reticulata did not affect the ache-induced hyperpolarization on this sub-set of dopaminergic neurons. |
1992-09-29 |
2023-08-11 |
Not clear |