| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S P Hume, A A Lammertsma, R Myers, S Rajeswaran, P M Bloomfield, S Ashworth, R A Fricker, E M Torres, I Watson, T Jone. The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease. Journal of neuroscience methods. vol 67. issue 2. 1997-01-14. PMID:8872875. |
using two models of human disease, namely striatal injection of ibotenic acid to produce postsynaptic cell loss as in huntington's disease, and 6-hydroxydopamine injection into substantia nigra pars compacta to mimic dopaminergic terminal loss in parkinson's disease, marked reductions in binding potential were observed for the corresponding pre- or postsynaptic markers. |
1997-01-14 |
2023-08-12 |
human |
| A Parent, M Fortin, P Y Côté, F Cicchett. Calcium-binding proteins in primate basal ganglia. Neuroscience research. vol 25. issue 4. 1997-01-06. PMID:8866512. |
in the substantia nigra/ventral tegmental area complex, calbindin and calretinin occur principally in dopaminergic neurons of the dorsal tier of the pars compacta and in those of the ventral tegmental area. |
1997-01-06 |
2023-08-12 |
human |
| Y J Liao, Y N Jan, L Y Ja. Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 22. 1996-12-19. PMID:8929423. |
girk2 immunoreactivity is found in but not limited to brain regions known to be affected in wv mice, such as the cerebellar granule cells and dopaminergic neurons in the substantia nigra pars compacta. |
1996-12-19 |
2023-08-12 |
mouse |
| C Marin, T M Engber, P Chaudhuri, A Peppe, T N Chas. Effects of kappa receptor agonists on D1 and D2 dopamine agonist and antagonist-induced behaviors. Psychopharmacology. vol 123. issue 2. 1996-12-03. PMID:8741947. |
striatal dynorphin-containing neurons receive dopaminergic inputs from the substantia nigra pars compacta and project primarily to the substantia nigra pars reticulata and entopeduncular nucleus. |
1996-12-03 |
2023-08-12 |
Not clear |
| J L Góngora-Alfaro, S Hernández-López, D Martínez-Fong, G Flores, J Aceve. Circling behavior elicited by cholinergic transmission in the substantia nigra pars compacta: involvement of nicotinic and muscarinic receptors. Neuroscience. vol 71. issue 3. 1996-12-03. PMID:8867045. |
we conclude that the pedunculopontine cholinergic neurons, which innervate the substantia nigra pars compacta, modulate the motor behavior by increasing the activity of dopaminergic nigrostriatal pathway. |
1996-12-03 |
2023-08-12 |
rat |
| E J Mufson, J S Kroin, Y T Liu, T Sobreviela, R D Penn, J A Miller, J H Kordowe. Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons. Neuroscience. vol 71. issue 1. 1996-11-27. PMID:8834401. |
sections from these cases dual-immunoreacted for brain-derived neurotrophic factor and tyrosine hydroxylase, the synthesizing enzyme for dopamine, revealed a subpopulation of pars compacta dopaminergic neurons which contained retrogradely transported brain-derived neurotrophic factor. |
1996-11-27 |
2023-08-12 |
monkey |
| B Piallat, A Benazzouz, A L Benabi. Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: behavioural and immunohistochemical studies. The European journal of neuroscience. vol 8. issue 7. 1996-11-06. PMID:8758948. |
since the substantia nigra compacta receives a moderate glutamatergic innervation from the subthalamic nucleus, we tried to determine whether subthalamic nucleus lesion could prevent the toxicity of the selective dopaminergic neurotoxin 6-hydroxydopamine (6-ohda). |
1996-11-06 |
2023-08-12 |
rat |
| T DeFazio, J P Wals. 'Intact' dopaminergic midbrain neurons of the rat display unclamped dendritic Ca2+ currents. Neuroscience letters. vol 208. issue 1. 1996-10-24. PMID:8731167. |
calcium channels play an important role in generating the complex electrophysiology of dopaminergic (daergic) neurons in the substantia nigra pars compacta (snc). |
1996-10-24 |
2023-08-12 |
rat |
| Y Smith, A Charara, A Paren. Synaptic innervation of midbrain dopaminergic neurons by glutamate-enriched terminals in the squirrel monkey. The Journal of comparative neurology. vol 364. issue 2. 1996-10-24. PMID:8788247. |
the type i terminals accounted for more than 70% of the total population of glutamate-enriched boutons in contact with dopaminergic cells in the dorsal and ventral tiers of the substantia nigra pars compacta as well as in the ventral tegmental area, whereas 5-20% of the glutamatergic synapses with dopaminergic neurons involved the two other types of terminals. |
1996-10-24 |
2023-08-12 |
squirrel_monkey |
| Y Smith, A Charara, A Paren. Synaptic innervation of midbrain dopaminergic neurons by glutamate-enriched terminals in the squirrel monkey. The Journal of comparative neurology. vol 364. issue 2. 1996-10-24. PMID:8788247. |
in contrast, less than 40% of the boutons in contact with dopaminergic dendrites were immunoreactive for glutamate in the dorsal and ventral tiers of the substantia nigra pars compacta. |
1996-10-24 |
2023-08-12 |
squirrel_monkey |
| Y Smith, A Charara, A Paren. Synaptic innervation of midbrain dopaminergic neurons by glutamate-enriched terminals in the squirrel monkey. The Journal of comparative neurology. vol 364. issue 2. 1996-10-24. PMID:8788247. |
the fact that the proportion of glutamatergic boutons in contact with dopaminergic cells is higher in the ventral tegmental area than in the substantia nigra pars compacta suggests that the different groups of midbrain dopaminergic neurons are modulated differently by extrinsic glutamatergic afferents in primates. |
1996-10-24 |
2023-08-12 |
squirrel_monkey |
| P G Overton, J F O'Callaghan, S A Greenfiel. Possible intermixing of neurons from the subthalamic nucleus and substantia nigra pars compacta in the guinea-pig. Experimental brain research. vol 107. issue 2. 1996-10-03. PMID:8773236. |
a population of cells in the anterior substantia nigra pars compacta (snpc) of the guinea-pig have been reported previously that differ from classical dopaminergic neurons in terms of their active and passive membrane properties. |
1996-10-03 |
2023-08-12 |
Not clear |
| W R Galpern, D M Frim, S B Tatter, C A Altar, M F Beal, O Isacso. Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration. Cell transplantation. vol 5. issue 2. 1996-08-27. PMID:8689033. |
supranigral implantation of fibroblasts genetically engineered to secrete bdnf attenuates the loss of substantia nigra pars compacta (snc) dopaminergic neurons associated with striatal infusion of mpp+ in the adult rat. |
1996-08-27 |
2023-08-12 |
rat |
| B Ford, C J Holmes, L Mainville, B E Jone. GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus. The Journal of comparative neurology. vol 363. issue 2. 1996-07-16. PMID:8642069. |
the double-labeled gad+/ct+ cells were commonly found ipsilaterally within 1) the deep mesencephalic reticular field, codistributed with putative glutamatergic projection neurons; 2) the ventral tegmental area, substantia nigra compacta, and retrorubral field, codistributed with dopaminergic projection neurons; 3) dorsal raphe, codistributed with serotonergic projection neurons; and 4) laterodorsal and pedunculopontine tegmental nuclei, codistributed with and in similar proportion to cholinergic projection cells (20-30% in ldtg). |
1996-07-16 |
2023-08-12 |
rat |
| P Damier, A Kastner, Y Agid, E C Hirsc. Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease? Neurology. vol 46. issue 5. 1996-06-21. PMID:8628464. |
within the substantia nigra pars compacta, most dopaminergic neurons were located in the dorsal part of the structure. |
1996-06-21 |
2023-08-12 |
human |
| P Damier, A Kastner, Y Agid, E C Hirsc. Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease? Neurology. vol 46. issue 5. 1996-06-21. PMID:8628464. |
the density of mao-b-positive glial cells varied in the control midbrains: high in the least affected dopaminergic group (the central gray substance) and low in the most affected region (the substantia nigra pars compacta). |
1996-06-21 |
2023-08-12 |
human |
| M Levivier, S Przedborski, C Bencsics, U J Kan. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 12. 1996-06-06. PMID:8613721. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by a progressive loss of the dopaminergic neurons of the substantia nigra pars compacta (snpc). |
1996-06-06 |
2023-08-12 |
rat |
| N L Ostrowski, A Per. Substantia nigra opiate receptors on basal ganglia efferents. Brain research bulletin. vol 38. issue 6. 1996-03-25. PMID:8590072. |
selective brain lesions were combined with quantitative autoradiography to determine whether opiate receptors are on dopaminergic somata and/or processes in the substantia nigra pars compacta and ventral tegmental area. |
1996-03-25 |
2023-08-12 |
Not clear |
| W de Jong, A C Linthorst, H G Verstee. The nigrostriatal dopamine system and the development of hypertension in the spontaneously hypertensive rat. Archives des maladies du coeur et des vaisseaux. vol 88. issue 8. 1996-03-04. PMID:8572872. |
this normalization of dopaminergic activity may be the causal factor underlying the attenuation of the development of hypertension in shr after bilateral lesioning of the pars compacta, of the substantia nigra. |
1996-03-04 |
2023-08-12 |
rat |
| S Prisco, E Esposit. Differential effects of acute and chronic fluoxetine administration on the spontaneous activity of dopaminergic neurones in the ventral tegmental area. British journal of pharmacology. vol 116. issue 2. 1996-02-01. PMID:8528581. |
electrophysiological techniques were used to study the effects of fluoxetine and citalopram on the basal activity of dopaminergic neurones in the ventral tegmental area (vta) and substantia nigra, pars compacta (snc) of rats. |
1996-02-01 |
2023-08-12 |
rat |