| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Galli, G Godeheu, F Artaud, J M Desce, A Pittaluga, L Barbeito, J Glowsinki, A Chéram. Specific role of N-acetyl-aspartyl-glutamate in the in vivo regulation of dopamine release from dendrites and nerve terminals of nigrostriatal dopaminergic neurons in the cat. Neuroscience. vol 42. issue 1. 1991-08-30. PMID:1861773. |
n-acetyl-aspartyl-glutamate interacted with dopaminergic neurons not only presynaptically in the caudate nucleus but also in the substantia nigra since a marked increase in [3h]dopamine release was observed both from local dendrites and from nerve terminals in the ipsilateral caudate nucleus when n-acetyl-aspartyl-glutamate (10(-7) m) was infused locally into the substantia nigra pars compacta. |
1991-08-30 |
2023-08-11 |
cat |
| W H Yung, M A Häusser, J J Jac. Electrophysiology of dopaminergic and non-dopaminergic neurones of the guinea-pig substantia nigra pars compacta in vitro. The Journal of physiology. vol 436. 1991-08-08. PMID:2061849. |
electrophysiology of dopaminergic and non-dopaminergic neurones of the guinea-pig substantia nigra pars compacta in vitro. |
1991-08-08 |
2023-08-11 |
Not clear |
| M Herkenham, M D Little, K Bankiewicz, S C Yang, S P Markey, J N Johannesse. Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study. Neuroscience. vol 40. issue 1. 1991-07-22. PMID:2052148. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) selectively destroys dopaminergic neurons of the substantia nigra pars compacta in humans and other primates, producing a parkinsonian condition. |
1991-07-22 |
2023-08-11 |
monkey |
| E Palombo, L J Porrino, A M Crane, K S Bankiewicz, I J Kopin, L Sokolof. Cerebral metabolic effects of monoamine oxidase inhibition in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine acutely treated monkeys. Journal of neurochemistry. vol 56. issue 5. 1991-05-16. PMID:2013759. |
the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) induces dopaminergic cell death in the substantia nigra pars compacta (snpc) and clinical parkinsonism in humans and experimental animals. |
1991-05-16 |
2023-08-11 |
monkey |
| I Leroux-Nicollet, F Darchen, D Scherman, J Costenti. Postnatal development of the monoamine vesicular transporter in mesencephalic and telencephalic regions of the rat brain: a quantitative autoradiographic study with [3H]dihydrotetrabenazine. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:2290604. |
the density of binding sites almost attained the adult level at day 20 postnatal in regions rich in dopaminergic cell bodies (substantia nigra pars compacta and ventral tegmental area), as well as in the lateral septum. |
1991-04-01 |
2023-08-11 |
rat |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
in vitro extracellular single unit recordings were made from midbrain dopaminergic neurons in the substantia nigra pars compacta (nucleus a9) and ventral tegmental area (nucleus a10) of balb/cj mice. |
1991-03-19 |
2023-08-11 |
mouse |
| L T Weiss-Wunder, M F Chessele. Heterogeneous distribution of cytochrome oxidase activity in the rat substantia nigra: correlation with tyrosine hydroxylase and dynorphin immunoreactivities. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:1980845. |
neurons of the substantia nigra pars compacta (snc), ventral tegmental area, and ventrally displaced dopaminergic neurons were characterized by little or no staining for coase. |
1991-03-19 |
2023-08-11 |
rat |
| D M Gao, L Jeaugey, P Pollak, A L Benabi. Intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:2282499. |
intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. |
1991-03-19 |
2023-08-11 |
rat |
| L Turski, K Bressler, K J Rettig, P A Löschmann, H Wachte. Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Nature. vol 349. issue 6308. 1991-03-11. PMID:1846943. |
we therefore sought to determine whether antagonists active at the nmda or quisqualate subtypes of l-glutamate receptors prevent toxicity of either mpp+ (1-methyl-4-phenyl-pyridinium ion, the active metabolite of mptp) or the selective dopaminergic neurotoxin 6-ohda in the rat substantia nigra pars compacta. |
1991-03-11 |
2023-08-11 |
rat |
| M F Kritzer, R B Innis, P S Goldman-Raki. Regional distribution of cholecystokinin binding sites in macaque basal ganglia determined by in vitro receptor autoradiography. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:2255400. |
the confinement of binding sites to the dorsal pars reticulata suggests an association with dendrites of pars compacta neurons which invade this region; this interpretation is consistent with recent evidence of depletion of nigral cholecystokinin binding sites in macaques following chemical lesion of dopaminergic cells of the par compacta. |
1991-01-24 |
2023-08-11 |
monkey |
| M F Pozza, H R Olpe, F Brugger, G E Fag. Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. European journal of pharmacology. vol 182. issue 1. 1990-10-19. PMID:1976098. |
nmda excited dopaminergic cells in the pars compacta region of the substantia nigra in a concentration-dependent manner. |
1990-10-19 |
2023-08-11 |
rat |
| M F Piercey, J T Lu. Electrophysiological effects of dopamine autoreceptor antagonists, (+)-AJ 76 and (+)-UH 232. European journal of pharmacology. vol 182. issue 2. 1990-10-17. PMID:2397740. |
the weak aminotetralin stimulants, (+)-aj 76, cis-(+)-5-methoxy-1-methyl-2-(n-propylamino)tetralin and (+)-uh 232, cis-(+)-5-methoxy-1-methyl-2-(di-n-propylamino)tetralin, were tested for their effects on firing rates of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc). |
1990-10-17 |
2023-08-11 |
Not clear |
| V La Grutta, M Sabatin. Substantia nigra-mediated anticonvulsant action: a possible role of a dopaminergic component. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:2357581. |
since there is probably an anatomical nigrohippocampal pathway arising from dopaminergic cells in the substantia nigra, we tested the effects of stimulating the substantia nigra pars compacta (snpc) on focal hippocampal epilepsy induced by penicillin injection in the cat. |
1990-08-01 |
2023-08-11 |
cat |
| W C Graham, C E Clarke, S Boyce, M A Sambrook, A R Crossman, G N Woodruf. Autoradiographic studies in animal models of hemi-parkinsonism reveal dopamine D2 but not D1 receptor supersensitivity. II. Unilateral intra-carotid infusion of MPTP in the monkey (Macaca fascicularis). Brain research. vol 514. issue 1. 1990-07-31. PMID:2192772. |
the selective dopaminergic antagonist ligands [3h]sch 23390 and [3h]sulpiride were used to reveal autoradiographically dopamine d1 and d2 receptors, respectively, in brain sections from monkeys which had received unilateral intracarotid infusions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), causing loss of dopamine-containing neurones of the substantia nigra pars compacta. |
1990-07-31 |
2023-08-11 |
monkey |
| K S Bankiewicz, R J Plunkett, D M Jacobowitz, L Porrino, U di Porzio, W T London, I J Kopin, E H Oldfiel. The effect of fetal mesencephalon implants on primate MPTP-induced parkinsonism. Histochemical and behavioral studies. Journal of neurosurgery. vol 72. issue 2. 1990-02-21. PMID:2295921. |
since th-immunoreactive cell bodies of the substantia nigra compacta (a-9 cells) were destroyed by mptp treatment and the ventral tegmental area (a-10) remained intact, it is concluded that sprouting of remaining host dopaminergic fibers occurs. |
1990-02-21 |
2023-08-11 |
monkey |
| C E Clarke, S Boyce, R G Robertson, M A Sambrook, A R Crossma. Drug-induced dyskinesia in primates rendered hemiparkinsonian by intracarotid administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Journal of the neurological sciences. vol 90. issue 3. 1989-07-31. PMID:2786926. |
a massive depletion of large, presumably dopaminergic cells was found from the ipsilateral substantia nigra pars compacta. |
1989-07-31 |
2023-08-11 |
monkey |
| M Savasta, E Ruberte, J M Palacios, G Mengo. The colocalization of cholecystokinin and tyrosine hydroxylase mRNAs in mesencephalic dopaminergic neurons in the rat brain examined by in situ hybridization. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2566954. |
6-hydroxydopamine-induced destruction of mesostriatal dopaminergic neurons resulted in a complete loss of cholecystokinin and tyrosine hydroxylase mrna expression throughout the substantia nigra pars compacta, indicating that all cholecystokinin expressing cells are 6-hydroxydopamine-sensitive. |
1989-07-07 |
2023-08-11 |
rat |
| G M Pasinetti, S P Lerner, S A Johnson, D G Morgan, N A Telford, C E Finc. Chronic lesions differentially decrease tyrosine hydroxylase messenger RNA in dopaminergic neurons of the substantia nigra. Brain research. Molecular brain research. vol 5. issue 3. 1989-06-23. PMID:2566883. |
nine months after unilateral 6-hydroxydopamine (6-ohda) lesions of the substantia nigra pars compacta (s. nigra), the remaining dopaminergic (daergic) neurons (tyrosine hydroxylase (th) cells determined by immunocytochemistry (icc] on the lesioned side were atrophic with smaller nucleoli. |
1989-06-23 |
2023-08-11 |
Not clear |
| S J O'Dell, J F Marshal. Transport of [3H]mazindol binding sites in mesostriatal dopamine axons. Brain research. vol 460. issue 2. 1989-03-27. PMID:3147121. |
6-hydroxydopamine injections along mesostriatal dopaminergic axons can be used to interrupt axonal transport from cell bodies in the substantia nigra pars compacta to terminal fields in the striatum. |
1989-03-27 |
2023-08-11 |
Not clear |
| P V Piazza, M Ferdico, D Russo, G Crescimanno, A Benigno, G Amat. The influence of dopaminergic A10 neurons on the motor pattern evoked by substantia nigra (pars compacta) stimulation. Behavioural brain research. vol 31. issue 3. 1989-03-22. PMID:2914078. |
the influence of dopaminergic a10 neurons on the motor pattern evoked by substantia nigra (pars compacta) stimulation. |
1989-03-22 |
2023-08-11 |
Not clear |