| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Pan, Jing Qian, Yu Zhang, Jianfang Ma, Gang Wang, Qin Xiao, Shengdi Chen, Jianqing Din. Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway. Laboratory investigation; a journal of technical methods and pathology. vol 90. issue 2. 2010-04-09. PMID:20010851. |
the death of dopaminergic neurons and the loss of dopaminergic axon in the striatum were significantly suppressed by infusion of the peptide tat-jbd in mptp-treated mice. |
2010-04-09 |
2023-08-12 |
mouse |
| Anne K Meyer, Martina Maisel, Andreas Hermann, Katja Stirl, Alexander Storc. Restorative approaches in Parkinson's Disease: which cell type wins the race? Journal of the neurological sciences. vol 289. issue 1-2. 2010-04-05. PMID:19733367. |
parkinson's disease (pd) is a progressive neurodegenerative movement disorder and is characterized by a continuous and selective loss of dopaminergic neurons in the midbrain with a subsequent reduction of the neurotransmitter dopamine in the striatum. |
2010-04-05 |
2023-08-12 |
Not clear |
| Cheryl A Frye, Sandra M Petralia, Madeline E Rhodes, Joseph F DeBol. 6-hydroxydopamine lesions enhance progesterone-facilitated lordosis of rats and hamsters, independent of effects on motor behavior. Physiology & behavior. vol 99. issue 2. 2010-04-05. PMID:19778544. |
we investigated the importance of dopaminergic neurons in the vta, and two dopaminergic projection sites, the nucleus accumbens (nac), and caudate nucleus of the striatum (cn), in modulating p(4)-facilitated sex and motor behavior. |
2010-04-05 |
2023-08-12 |
rat |
| Lawrence S Kegeles, Anissa Abi-Dargham, W Gordon Frankle, Roberto Gil, Thomas B Cooper, Mark Slifstein, Dah-Ren Hwang, Yiyun Huang, Suzanne N Haber, Marc Laruell. Increased synaptic dopamine function in associative regions of the striatum in schizophrenia. Archives of general psychiatry. vol 67. issue 3. 2010-03-17. PMID:20194823. |
a long-standing version of the dopamine hypothesis of schizophrenia postulates that hyperactivity of dopaminergic transmission at d(2) receptors in the limbic striatum is associated with the illness and that blockade of mesolimbic d(2) receptors is responsible for the antipsychotic action of d(2) receptor antagonists. |
2010-03-17 |
2023-08-12 |
Not clear |
| Iris Machado de Oliveira, Brenda Viviane Ferreira Nunes, Durán Rafael Barbosa, Alfonso Miguel Pallares, Lilian Rosana Ferreira Far. Effects of the neonicotinoids thiametoxam and clothianidin on in vivo dopamine release in rat striatum. Toxicology letters. vol 192. issue 3. 2010-03-05. PMID:19900516. |
in the present work it was studied and characterized the effects of tmx and clo, in different concentrations, on dopaminergic system of rat striatum using in vivo brain microdialysis coupled to hplc-ec. |
2010-03-05 |
2023-08-12 |
rat |
| Barbara Monti, Valentina Gatta, Francesca Piretti, Simonetta S Raffaelli, Marco Virgili, Antonio Contestabil. Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein. Neurotoxicity research. vol 17. issue 2. 2010-03-02. PMID:19626387. |
the decrease of the dopaminergic marker tyrosine hydroxylase in substantia nigra and striatum caused by 7 days toxin administration was prevented in vpa-fed rats. |
2010-03-02 |
2023-08-12 |
rat |
| Elzbieta Lorenc-Koci, Krystyna Gołembiowska, Małgorzata Pietraszek, Jadwiga Warda. Treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3H]MK-801 to NMDA receptors in the dopaminergic structures of the rat brain. Pharmacological reports : PR. vol 61. issue 5. 2010-02-26. PMID:19904002. |
treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3h]mk-801 to nmda receptors in the dopaminergic structures of the rat brain. |
2010-02-26 |
2023-08-12 |
rat |
| Elzbieta Lorenc-Koci, Krystyna Gołembiowska, Małgorzata Pietraszek, Jadwiga Warda. Treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3H]MK-801 to NMDA receptors in the dopaminergic structures of the rat brain. Pharmacological reports : PR. vol 61. issue 5. 2010-02-26. PMID:19904002. |
this study aimed to examine the effect of acute administration of 1,2,3,4-tetrahydroisoquinoline (tiq), an endo- and exogenous amine suspected of inducing parkinsonism in humans on the release of glutamate in the striatum as well as to assess the impact of its chronic treatment on the binding of [(3)h]mk-801 to nmda receptors in the dopaminergic structures of the rat brain. |
2010-02-26 |
2023-08-12 |
rat |
| J Ng, A J Rashid, C H So, B F O'Dowd, S R Georg. Activation of calcium/calmodulin-dependent protein kinase IIalpha in the striatum by the heteromeric D1-D2 dopamine receptor complex. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19837142. |
using the dopaminergic agonist skf83959, which selectively activates the d1-d2 complex, we demonstrated phosphorylation of camkiialpha at threonine 286, both in heterologous cells and in the murine striatum in vivo. |
2010-02-24 |
2023-08-12 |
Not clear |
| Jennifer Barber-Singh, Byoung Boo Seo, Eiko Nakamaru-Ogiso, Yuen-Sum Lau, Akemi Matsuno-Yagi, Takao Yag. Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder. Rejuvenation research. vol 12. issue 4. 2010-02-16. PMID:19653878. |
we showed that expression of ndi1 was able to significantly prevent the loss of dopamine and tyrosine hydroxylase as well as the dopaminergic transporters in the striatum of the chronic parkinsonian mice. |
2010-02-16 |
2023-08-12 |
mouse |
| Mei Liu, Dong-Young Choi, Randy L Hunter, Jignesh D Pandya, Wayne A Cass, Patrick G Sullivan, Hyoung-Chun Kim, Don M Gash, Guoying Bin. Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats. Journal of neurochemistry. vol 112. issue 3. 2010-02-16. PMID:19922440. |
in our experiments, oral administration of trichloroethylene induced a significant loss of dopaminergic neurons in the substantia nigra pars compacta in a dose-dependent manner, whereas the number of both cholinergic and gabaergic neurons were not decreased in the striatum. |
2010-02-16 |
2023-08-12 |
rat |
| Merav Bahat-Stroomza, Yael Barhum, Yossef S Levy, Olga Karpov, Shlomo Bulvik, Eldad Melamed, Daniel Offe. Induction of adult human bone marrow mesenchymal stromal cells into functional astrocyte-like cells: potential for restorative treatment in Parkinson's disease. Journal of molecular neuroscience : MN. vol 39. issue 1-2. 2010-02-12. PMID:19127447. |
it has been suggested that treatment with neurotrophic factors (ntfs) might protect and prevent death of the surviving dopaminergic neurons and induce proliferation of their axonal nerve terminals with reinnervations of the deafferented striatum. |
2010-02-12 |
2023-08-12 |
human |
| R Bouali-Benazzouz, C H Tai, J Chetrit, A Benazzou. Intrapallidal injection of 6-hydroxydopamine induced changes in dopamine innervation and neuronal activity of globus pallidus. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19628021. |
our results support the premise of the existence of collaterals of snc dopaminergic axons projecting to the striatum and gp and that dopamine plays a role in the modulation of the firing rate but not the firing pattern of gp neurons. |
2010-02-12 |
2023-08-12 |
rat |
| H Haghir, S Kovac, E-J Speckmann, K Zilles, A Gorj. Patterns of neurotransmitter receptor distributions following cortical spreading depression. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19665048. |
cortical sd also upregulated nmda, ampa, kainate, gaba(a), serotonergic 5-ht(2), adrenergic alpha(2) and dopaminergic d1 receptor binding sites in the striatum. |
2010-02-12 |
2023-08-12 |
rat |
| Yi-Fang Cui, Gunnar Hargus, Jin-Chong Xu, Janinne Sylvie Schmid, Yan-Qin Shen, Markus Glatzel, Melitta Schachner, Christian Bernreuthe. Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice. Brain : a journal of neurology. vol 133. issue Pt 1. 2010-02-12. PMID:19995872. |
female c57bl/6j mice (2 months old) were treated with the mitochondrial toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intraperitoneally to deplete dopaminergic neurons selectively, followed by unilateral transplantation of stem cell-derived neural aggregates into the striatum. |
2010-02-12 |
2023-08-12 |
mouse |
| Yi-Fang Cui, Gunnar Hargus, Jin-Chong Xu, Janinne Sylvie Schmid, Yan-Qin Shen, Markus Glatzel, Melitta Schachner, Christian Bernreuthe. Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice. Brain : a journal of neurology. vol 133. issue Pt 1. 2010-02-12. PMID:19995872. |
morphological analysis revealed increased numbers and migration of surviving transplanted cells, as well as increased numbers of dopaminergic neurons, leading to enhanced levels of dopamine in the striatum ipsilateral to the grafted side in l1 overexpressing stem cell-derived neural aggregates, when compared to wild-type stem cell-derived neural aggregates. |
2010-02-12 |
2023-08-12 |
mouse |
| Martin Darvas, Richard D Palmite. Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089924. |
dopaminergic projections to the ventral and dorsomedial striatum are important for reward, motivation, and goal-directed learning, whereas projections to the dorsolateral striatum are implicated in motor control, habitual enactment of motor skills, visuospatial learning, and memory. |
2010-02-05 |
2023-08-12 |
mouse |
| Karima Azdad, Marcelo Chàvez, Patrick Don Bischop, Pim Wetzelaer, Bart Marescau, Peter Paul De Deyn, David Gall, Serge N Schiffman. Homeostatic plasticity of striatal neurons intrinsic excitability following dopamine depletion. PloS one. vol 4. issue 9. 2010-02-01. PMID:19730738. |
dopaminergic neurons that innervate striatum die in parkinson disease, leading to inefficient adaptive behaviour. |
2010-02-01 |
2023-08-12 |
Not clear |
| Rachel Hammond, Sandra Blaess, Asa Abeliovic. Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19774071. |
midbrain dopaminergic axons project from the substantia nigra (sn) and the ventral tegmental area (vta) to rostral target tissues, including the striatum, pallidum, and hypothalamus. |
2010-02-01 |
2023-08-12 |
mouse |
| Hye-Jean Park, Feng Ji Cui, Jae Woo Roh, Young Chul Jung, Se Hyun Kim, Yong Sik Kim, Ung Gu Kan. Effects of electroconvulsive shock on the phosphorylation of DARPP-32 in rat striatum. Psychiatry research. vol 170. issue 1. 2010-02-01. PMID:19818513. |
dopamine- and camp-regulated phosphoprotein with molecular weight 32 kda (darpp-32) is a key integrative molecule in the dopaminergic and glutamatergic signaling pathways in the striatum. |
2010-02-01 |
2023-08-12 |
rat |