| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Xu, Z Xiong, Y Yong, Z Wang, Z Ke, Z Xia, Y H. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum. Neuroscience. vol 167. issue 1. 2010-06-17. PMID:20123001. |
catalpol attenuates mptp induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum. |
2010-06-17 |
2023-08-12 |
mouse |
| Prokopios Magiatis, Panagiotis Polychronopoulos, Alexios-Leandros Skaltsounis, Olivier Lozach, Laurent Meijer, Diane B Miller, James P O'Callagha. Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis. Neurotoxicology and teratology. vol 32. issue 2. 2010-06-15. PMID:20034560. |
all indirubins examined decreased various measures associated with dopaminergic neurotransmission in striatum. |
2010-06-15 |
2023-08-12 |
mouse |
| Christoph Kellendon. Modeling excess striatal D2 receptors in mice. Progress in brain research. vol 179. 2010-06-15. PMID:20302818. |
dopaminergic hyperactivity in the striatum has been one of the most replicated physiological findings in patients with schizophrenia. |
2010-06-15 |
2023-08-12 |
mouse |
| María Clara Pott Godoy, Carina Cintia Ferrari, Fernando Juan Pitoss. Nigral neurodegeneration triggered by striatal AdIL-1 administration can be exacerbated by systemic IL-1 expression. Journal of neuroimmunology. vol 222. issue 1-2. 2010-06-14. PMID:20350768. |
by injecting an adenovirus expressing il-1 in the striatum, we provoked progressive neurodegeneration of dopaminergic cells in the substantia nigra, motor symptoms and microglial activation. |
2010-06-14 |
2023-08-12 |
Not clear |
| Vincenza Bagetta, Veronica Ghiglieri, Carmelo Sgobio, Paolo Calabresi, Barbara Piccon. Synaptic dysfunction in Parkinson's disease. Biochemical Society transactions. vol 38. issue 2. 2010-06-11. PMID:20298209. |
it has been suggested that their impairment could account for the onset and progression of motor symptoms of pd (parkinson's disease), a neurodegenerative disorder characterized by the massive degeneration of dopaminergic neurons projecting to the striatum. |
2010-06-11 |
2023-08-12 |
Not clear |
| Paola Devoto, Giovanna Flor. On the origin of cortical dopamine: is it a co-transmitter in noradrenergic neurons? Current neuropharmacology. vol 4. issue 2. 2010-06-09. PMID:18615131. |
moreover, microdialysis studies in rats have shown how pharmacological treatments that induce modifications of extracellular na in the medial pfc (mpfc), also produce parallel changes in extracellular da.to explain the coupling of na and da changes, this article reviews the evidence supporting the hypothesis that extracellular da in the cerebral cortex originates not only from dopaminergic terminals but also from noradrenergic ones, where it acts both as precursor for na and as a co-transmitter.accordingly, extracellular da concentration in the occipital, parietal and cerebellar cortex was found to be much higher than expected in view of the scarce dopaminergic innervation in these areas.systemic administration or intra-cortical perfusion of alpha(2)-adrenoceptor agonists and antagonists, consistent with their action on noradrenergic neuronal activity, produced concomitant changes not only in extracellular na but also in da in the mpfc, occipital and parietal cortex.chemical modulation of the locus coeruleus by locally applied carbachol, kainate, nmda or clonidine modified both na and da in the mpfc.electrical stimulation of the locus coeruleus led to an increased efflux of both na and da in mpfc, parietal and occipital cortex, while in the striatum, na efflux alone was enhanced.atypical antipsychotics, such as clozapine and olanzapine, or antidepressants, including mirtazapine and mianserine, have been found to increase both na and da throughout the cerebral cortex, likely through blockade of alpha(2)-adrenoceptors. |
2010-06-09 |
2023-08-12 |
rat |
| Markus Ullsperge. Genetic association studies of performance monitoring and learning from feedback: the role of dopamine and serotonin. Neuroscience and biobehavioral reviews. vol 34. issue 5. 2010-06-02. PMID:19563825. |
different hypotheses on the interaction of the rostral cingulate zone, the striatum, and the mesencephalic dopaminergic nuclei are discussed. |
2010-06-02 |
2023-08-12 |
Not clear |
| José Luis Góngora-Alfar. [Caffeine as a preventive drug for Parkinson's disease: epidemiologic evidence and experimental support]. Revista de neurologia. vol 50. issue 4. 2010-05-18. PMID:20198594. |
recently, it was shown that male rats treated with moderate doses of caffeine (5 mg/kg/day) during six months, followed by a withdrawal period of at least two weeks, developed a greater resistance to the catalepsy induced with the dopaminergic antagonist haloperidol, which was possibly mediated by an increase of dopaminergic transmission in the corpus striatum. |
2010-05-18 |
2023-08-12 |
human |
| L Prensa, J M Giménez-Amaya, A Parent, J Bernácer, C Cebriá. The nigrostriatal pathway: axonal collateralization and compartmental specificity. Journal of neural transmission. Supplementum. issue 73. 2010-05-14. PMID:20411767. |
in humans, the compartmental specificity of the nigrostriatal pathway is revealed by the fact that the matrix compartment is densely innervated by dopaminergic fibers, whereas the striosomes display different densities of dopaminergic terminals depending on their location within the striatum. |
2010-05-14 |
2023-08-12 |
human |
| Alice Egerton, Arsime Demjaha, Philip McGuire, Mitul A Mehta, Oliver D Howe. The test-retest reliability of 18F-DOPA PET in assessing striatal and extrastriatal presynaptic dopaminergic function. NeuroImage. vol 50. issue 2. 2010-05-11. PMID:20034580. |
these data confirm the utility of 18f-dopa pet in assessing dopaminergic function in the striatum and select extrastriatal areas but highlight the limitations in using this approach to measure dopaminergic function in low uptake extrastriatal brain areas. |
2010-05-11 |
2023-08-12 |
human |
| Darren Goffin, Afia B Ali, Nazir Rampersaud, Alexander Harkavyi, Celine Fuchs, Peter S Whitton, Angus C Nairn, Jasmina N Jovanovi. Dopamine-dependent tuning of striatal inhibitory synaptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 8. 2010-05-04. PMID:20181591. |
dopaminergic projections to the striatum, crucial for the correct functioning of this brain region in adulthood, are known to be established early in development, but their role is currently uncharacterized. |
2010-05-04 |
2023-08-12 |
Not clear |
| Youngbin Kwak, Martijn L T M Müller, Nicolaas I Bohnen, Praveen Dayalu, Rachael D Seidle. Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease. Journal of neurophysiology. vol 103. issue 2. 2010-05-03. PMID:20018839. |
early parkinson's disease (pd) is mainly characterized by dopaminergic denervation of the dorsal and posterior striatum while sparing anterior and ventral regions. |
2010-05-03 |
2023-08-12 |
human |
| Youngbin Kwak, Martijn L T M Müller, Nicolaas I Bohnen, Praveen Dayalu, Rachael D Seidle. Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease. Journal of neurophysiology. vol 103. issue 2. 2010-05-03. PMID:20018839. |
dopaminergic medication improves dorsal and posterior striatum function by compensating for the loss of dopamine. |
2010-05-03 |
2023-08-12 |
human |
| Youngbin Kwak, Martijn L T M Müller, Nicolaas I Bohnen, Praveen Dayalu, Rachael D Seidle. Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease. Journal of neurophysiology. vol 103. issue 2. 2010-05-03. PMID:20018839. |
however, previous work has shown that dopaminergic medication interferes with the ventral and anterior striatum function by overdosing this relatively intact structure in early-state pd. |
2010-05-03 |
2023-08-12 |
human |
| Jianjun Wu, Wenbo Yu, Yan Chen, Yaru Su, Zhengtong Ding, Huimin Ren, Yuping Jiang, Jian Wan. Intrastriatal transplantation of GDNF-engineered BMSCs and its neuroprotection in lactacystin-induced Parkinsonian rat model. Neurochemical research. vol 35. issue 3. 2010-04-30. PMID:19894114. |
we observed that the intrastriatal transplantation of gdnf-bmscs could significantly rescue the dopaminergic neurons from lactacystin-induced neurotoxicity with regard to behavioral recovery, tyrosine hydroxylase level in nigra and striatum, and striatal dopamine level. |
2010-04-30 |
2023-08-12 |
rat |
| Minori Nishiguchi, Hiroshi Kinoshita, Shogo Kasuda, Montonori Takahashi, Takehiko Yamamura, Kiyoshi Matsui, Harumi Ouchi, Takako Minami, Shigeru Hishida, Hajime Nishi. Effects of dopamine antagonists on methamphetamine-induced dopamine release in high and low alcohol preference rats. Toxicology mechanisms and methods. vol 20. issue 3. 2010-04-30. PMID:20163290. |
these data suggested that alcohol preference is associated with the action of map, and the dopaminergic mechanism, specifically the d1 system in the striatum, might have a different pathway dependent on alcohol preference. |
2010-04-30 |
2023-08-12 |
rat |
| Maryka Quik, Carla Campos, Neeraja Parameswaran, J William Langston, J Michael McIntosh, Michael Yeluashvil. Chronic nicotine treatment increases nAChRs and microglial expression in monkey substantia nigra after nigrostriatal damage. Journal of molecular neuroscience : MN. vol 40. issue 1-2. 2010-04-21. PMID:19685015. |
our previous work had shown that long-term nicotine administration improved dopaminergic markers and nicotinic receptors (nachrs) in the striatum of monkeys with nigrostriatal damage. |
2010-04-21 |
2023-08-12 |
monkey |
| Naila Rasheed, Ausaf Ahmad, Chandra Prakash Pandey, Rajnish Kumar Chaturvedi, Mohtashim Lohani, Gautam Pali. Differential response of central dopaminergic system in acute and chronic unpredictable stress models in rats. Neurochemical research. vol 35. issue 1. 2010-04-19. PMID:19568932. |
we aimed to evaluate the response of dopaminergic system in acute stress (as) and chronic unpredictable stress (cus) by measuring dopamine (da) levels, its receptor densities in the frontal cortex, striatum, hippocampus, amygdala and orbito-frontal cortex regions of rat brain, and investigated the corresponding behavioral locomotor changes. |
2010-04-19 |
2023-08-12 |
rat |
| Ana C Barceló, B Fillipini, Jorge Horacio Paz. Study of the neural basis of striatal modulation of the jaw-opening reflex. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 2. 2010-04-12. PMID:20012111. |
previous experimental data from this laboratory demonstrated the participation of the striatum and dopaminergic pathways in central nociceptive processing. |
2010-04-12 |
2023-08-12 |
rat |
| Kazuto Sakoori, Niall P Murph. Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice. Neuroscience letters. vol 469. issue 3. 2010-04-12. PMID:20025929. |
a major pathology of methamphetamine abuse is loss of dopaminergic function due to destruction of dopaminergic terminals, especially in the striatum. |
2010-04-12 |
2023-08-12 |
mouse |