| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Cieślak, Michał Komoszyński, Andrzej Wojtcza. Adenosine A(2A) receptors in Parkinson's disease treatment. Purinergic signalling. vol 4. issue 4. 2011-07-14. PMID:18438720. |
co-localization of adenosine a(2a) and dopaminergic d2 receptors in striatum creates a milieu for antagonistic interaction between adenosine and dopamine. |
2011-07-14 |
2023-08-12 |
Not clear |
| Torsten Falk, Shiling Zhang, Scott J Sherma. Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease. Molecular neurodegeneration. vol 4. 2011-07-14. PMID:20003314. |
parkinson's disease (pd) results from the degeneration of dopaminergic neurons in the substantia nigra and the consequent deficit of dopamine released in the striatum. |
2011-07-14 |
2023-08-12 |
rat |
| Hongyu Wang, Xi Chen, Yuemei Li, Tie-Shan Tang, Ilya Bezprozvann. Tetrabenazine is neuroprotective in Huntington's disease mice. Molecular neurodegeneration. vol 5. 2011-07-14. PMID:20420689. |
tbz acts by reducing dopaminergic input to the striatum. |
2011-07-14 |
2023-08-12 |
mouse |
| M T Tadaiesky, P A Dombrowski, C Da Cunha, R N Takahash. Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease. Parkinson's disease. vol 2010. 2011-07-14. PMID:20976080. |
these findings suggest a role for cb(1) receptors in the early symptoms caused by degeneration of dopaminergic neurons in the striatum, as observed in parkinson's disease. |
2011-07-14 |
2023-08-12 |
rat |
| Susanne Graef, Guido Biele, Lea K Krugel, Frank Marzinzik, Michael Wahl, Johann Wotka, Fabian Klostermann, Hauke R Heekere. Differential influence of levodopa on reward-based learning in Parkinson's disease. Frontiers in human neuroscience. vol 4. 2011-07-14. PMID:21048900. |
the mesocorticolimbic dopamine (da) system linking the dopaminergic midbrain to the prefrontal cortex and subcortical striatum has been shown to be sensitive to reinforcement in animals and humans. |
2011-07-14 |
2023-08-12 |
Not clear |
| Karen S Rommelfanger, Thomas Wichman. Extrastriatal dopaminergic circuits of the Basal Ganglia. Frontiers in neuroanatomy. vol 4. 2011-07-14. PMID:21103009. |
dopamine has long been identified as an important modulator of basal ganglia function in the striatum, and disturbances of striatal dopaminergic transmission have been implicated in diseases such as parkinson's disease (pd), addiction and attention deficit hyperactivity disorder. |
2011-07-14 |
2023-08-12 |
Not clear |
| Karen S Rommelfanger, Thomas Wichman. Extrastriatal dopaminergic circuits of the Basal Ganglia. Frontiers in neuroanatomy. vol 4. 2011-07-14. PMID:21103009. |
however, recent evidence suggests that dopamine may also modulate basal ganglia function at sites outside of the striatum, and that changes in dopaminergic transmission at these sites may contribute to the symptoms of pd and other neuropsychiatric disorders. |
2011-07-14 |
2023-08-12 |
Not clear |
| Paola Bonsi, Dario Cuomo, Giuseppina Martella, Graziella Madeo, Tommaso Schirinzi, Francesca Puglisi, Giulia Ponterio, Antonio Pisan. Centrality of striatal cholinergic transmission in Basal Ganglia function. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21344017. |
loss of the reciprocal modulation between dopaminergic inputs and the intrinsic cholinergic innervation within the striatum appears to be the trigger for pathophysiological changes occurring in basal ganglia disorders. |
2011-07-14 |
2023-08-12 |
Not clear |
| Tahira Farooqui, Akhlaq A Farooqu. Lipid-mediated oxidative stress and inflammation in the pathogenesis of Parkinson's disease. Parkinson's disease. vol 2011. 2011-07-14. PMID:21403820. |
pd is characterized by the progressive loss of dopaminergic neurons in the substantia nigra, depletion of dopamine in the striatum, abnormal mitochondrial and proteasomal functions, and accumulation of α-synuclein that may be closely associated with pathological and clinical abnormalities. |
2011-07-14 |
2023-08-12 |
Not clear |
| I-Ching Lai, Mao-Liang Chen, Ying-Chieh Wang, Jen-Yeu Chen, Ding-Lieh Liao, Ya-Mei Bai, Chao-Cheng Lin, Tzu-Ting Chen, Ying-Jay Lio. Analysis of genetic variations in the human melatonin receptor (MTNR1A, MTNR1B) genes and antipsychotics-induced tardive dyskinesia in schizophrenia. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 12. issue 2. 2011-07-11. PMID:20726823. |
antipsychotics-induced tardive dyskinesia (td) has been suggested to be related to altered dopaminergic neurotransmission in the striatum. |
2011-07-11 |
2023-08-12 |
human |
| A Basta-Kaim, K Fijał, B Budziszewska, M Regulska, M Leśkiewicz, M Kubera, K Gołembiowska, W Lasoń, K Wędzon. Prenatal lipopolysaccharide treatment enhances MK-801-induced psychotomimetic effects in rats. Pharmacology, biochemistry, and behavior. vol 98. issue 2. 2011-07-08. PMID:21236292. |
these behavioral changes were accompanied by a decrease in the dopamine and its metabolite, dopac concentration in the frontal cortex, enhanced dopaminergic system activity in the striatum and no changes in noradrenaline (na) level. |
2011-07-08 |
2023-08-12 |
rat |
| Jean Lud Cadet, Christie Brannock, Irina N Krasnova, Bruce Ladenheim, Michael T McCoy, Jenny Chou, Elin Lehrmann, William H Wood, Kevin G Becker, Yun Wan. Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats. PloS one. vol 5. issue 12. 2011-07-05. PMID:21179447. |
the present experiments sought to identify genes that were affected in the dopamine (da)-denervated striatum after 6-hydroxydopamine-induced destruction of the nigrostriatal dopaminergic pathway in the rat. |
2011-07-05 |
2023-08-12 |
rat |
| Nobumi Miyake, Judy Thompson, Mette Skinbjerg, Anissa Abi-Dargha. Presynaptic dopamine in schizophrenia. CNS neuroscience & therapeutics. vol 17. issue 2. 2011-07-01. PMID:21199451. |
overall, these different imaging modalities have converged to show a dysregulation of presynaptic dopaminergic activity in schizophrenia, leading to excessive da release in the striatum, particularly in the projection to the associative striatum, an area of integration between cognitive and limbic cortical inputs. |
2011-07-01 |
2023-08-12 |
Not clear |
| E V Pushchin. [Morpho-functional and hodological peculiarities of ascending dopaminergic system of Rhodeus sericeus (Cyprinidae)]. Morfologiia (Saint Petersburg, Russia). vol 139. issue 1. 2011-06-08. PMID:21539082. |
six populations of th-immunopositive neurons were detected in the area of posterior tuberculum, two of them were double-labeled, indicating the presence of dopaminergic projections to the ventral portion of the telencephalon (striatum). |
2011-06-08 |
2023-08-12 |
Not clear |
| Collin J Lobb, Todd W Troyer, Charles J Wilson, Carlos A Paladin. Disinhibition bursting of dopaminergic neurons. Frontiers in systems neuroscience. vol 5. 2011-06-01. PMID:21617731. |
phasic activation of the d1-expressing medium spiny neurons in the striatum (d1str) produced disinhibition bursts in dopaminergic neurons through the direct pathway (d1str to snpr to snpc). |
2011-06-01 |
2023-08-12 |
Not clear |
| Yoshito Masamizu, Takashi Okada, Hidetoshi Ishibashi, Shin'ichi Takeda, Shigeki Yuasa, Kiyoshi Nakahar. Efficient gene transfer into neurons in monkey brain by adeno-associated virus 8. Neuroreport. vol 21. issue 6. 2011-05-31. PMID:20224455. |
cell typing with immunohistochemistry confirmed efficient aav8-mediated gene transfer into the pyramidal neurons in the cortex, calbindin-positive medium spiny neurons in the striatum and dopaminergic neurons in the substantia nigra. |
2011-05-31 |
2023-08-12 |
monkey |
| Sung W Choi, Akos A Gerencser, Donna W Lee, Subramanian Rajagopalan, David G Nicholls, Julie K Andersen, Martin D Bran. Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 12. 2011-05-27. PMID:21430153. |
as predicted, dopaminergic synaptosomes from striatum had lower respiratory rates. |
2011-05-27 |
2023-08-12 |
mouse |
| E Gramage, L Rossi, N Granado, R Moratalla, G Herradó. Genetic inactivation of pleiotrophin triggers amphetamine-induced cell loss in the substantia nigra and enhances amphetamine neurotoxicity in the striatum. Neuroscience. vol 170. issue 1. 2011-05-24. PMID:20620199. |
we found that amphetamine causes a significantly enhanced loss of dopaminergic terminals in the striatum of ptn-/- mice compared to wild type (wt+/+) mice. |
2011-05-24 |
2023-08-12 |
mouse |
| Sylvia Navailles, Philippe De Deurwaerdèr. Presynaptic control of serotonin on striatal dopamine function. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20953589. |
numerous biochemical and behavioral data indicate that serotonin (5-ht) affects dopaminergic terminal function in the striatum. |
2011-05-24 |
2023-08-12 |
Not clear |
| Dustin R Wakeman, Hemraj B Dodiya, Jeffrey H Kordowe. Cell transplantation and gene therapy in Parkinson's disease. The Mount Sinai journal of medicine, New York. vol 78. issue 1. 2011-05-24. PMID:21259269. |
parkinson's disease is a progressive neurodegenerative disorder affecting, in part, dopaminergic motor neurons of the ventral midbrain and their terminal projections that course to the striatum. |
2011-05-24 |
2023-08-12 |
Not clear |