Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R D Palmite. Dopamine signaling as a neural correlate of consciousness. Neuroscience. vol 198. 2012-03-22. PMID:21839810. |
therefore, i propose that dopaminergic modulation of glutamatergic inputs from the cortex and thalamus onto medium spiny neurons in the striatum contributes to cognition and the expression of consciousness. |
2012-03-22 |
2023-08-12 |
mouse |
D J Surmeier, L Carrillo-Reid, J Barga. Dopaminergic modulation of striatal neurons, circuits, and assemblies. Neuroscience. vol 198. 2012-03-22. PMID:21906660. |
this review attempts to summarize some of the key advances in this broad area, focusing on dopaminergic modulation of intrinsic excitability and synaptic plasticity in canonical microcircuits in the striatum as well as recent work suggesting that there are neuronal assemblies within the striatum devoted to particular types of computation and possibly action selection. |
2012-03-22 |
2023-08-12 |
Not clear |
Hideaki Kabuto, Tomoko T Yamanush. Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21769642. |
parkinson's disease (pd) is characterized by progressive degeneration of dopaminergic neurons in the nigrostriatal system and dopamine (da) depletion in the striatum. |
2012-03-12 |
2023-08-12 |
mouse |
Sarah A Heimovics, Katrina G Salvante, Keith W Sockman, Lauren V Riter. Individual differences in the motivation to communicate relate to levels of midbrain and striatal catecholamine markers in male European starlings. Hormones and behavior. vol 60. issue 5. 2012-03-09. PMID:21907203. |
results highlight a role for evolutionarily conserved dopaminergic projections from vta to striatum in the motivation to communicate and highlight novel patterns of catecholamine activity in area x, vta, and gct associated with individual differences in sexually-motivated and non-sexually-motivated communication. |
2012-03-09 |
2023-08-12 |
Not clear |
M Feb. A bold view of the lactating brain: functional magnetic resonance imaging studies of suckling in awake dams. Journal of neuroendocrinology. vol 23. issue 11. 2012-02-10. PMID:21722215. |
suckling was observed to increase blood-oxygen-level-dependent (bold) signal intensity in the midbrain, striatum and prefrontal cortex, which are areas that receive prominent dopaminergic inputs. |
2012-02-10 |
2023-08-12 |
rat |
b' A Anastas\\xc3\\xada, J Wojnacki, G A de Erausquin, D H Masc\\xc3\\xb. Glial cell-line derived neurotrophic factor is essential for electroconvulsive shock-induced neuroprotection in an animal model of Parkinson\'s disease. Neuroscience. vol 195. 2012-02-06. PMID:21871541.' |
we previously reported that ecs protects the integrity of the rat nigrostriatal dopaminergic system against 6-hydroxydopamine (6-ohda)-induced toxicity; in order to shed light into its neuroprotective mechanism, we studied glial cell-line derived neurotrophic factor (gdnf) levels (the most efficient tf for dopaminergic neurons) in the substantia nigra (sn) and striatum of 6-ohda-injected animals with or without ecs treatment. |
2012-02-06 |
2023-08-12 |
human |
Krishnan Sriram, Gary X Lin, Amy M Jefferson, Jenny R Roberts, Ronnee N Andrews, Michael L Kashon, James M Antonin. Manganese accumulation in nail clippings as a biomarker of welding fume exposure and neurotoxicity. Toxicology. vol 291. issue 1-3. 2012-02-06. PMID:22085607. |
trace element analysis revealed selective mn accumulation in dopaminergic brain areas, striatum (str) and midbrain (mb), following exposure to the two fumes. |
2012-02-06 |
2023-08-12 |
rat |
Afsaneh Gaillard, Mohamed Jabe. Rewiring the brain with cell transplantation in Parkinson's disease. Trends in neurosciences. vol 34. issue 3. 2012-01-23. PMID:21316770. |
here, we discuss recent findings showing that intranigral transplanted dopaminergic neuroblasts can form axonal projections to the striatum, resulting in increased striatal dopamine levels and ameliorating behavioral deficits in animal models of pd. |
2012-01-23 |
2023-08-12 |
Not clear |
Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
striatum is rich in opioid peptides and opioid receptors, and striatal opioidergic neurons are engaged in a bidirectional communication with midbrain dopaminergic neurons, closely regulating each other's activity. |
2012-01-18 |
2023-08-12 |
Not clear |
Y Masamizu, T Okada, K Kawasaki, H Ishibashi, S Yuasa, S Takeda, I Hasegawa, K Nakahar. Local and retrograde gene transfer into primate neuronal pathways via adeno-associated virus serotype 8 and 9. Neuroscience. vol 193. 2012-01-18. PMID:21782903. |
injections of either aav8-egfp or aav9-egfp into the marmoset striatum resulted in egfp expression in local striatal neurons as a result of local infection, as well as expression in dopaminergic neurons of the substantia nigra via retrograde transport along nigrostriatal axonal projections. |
2012-01-18 |
2023-08-12 |
monkey |
Zhifeng Qi, Weiwei Yang, Yujun Liu, Tao Cui, Hua Gao, Chunli Duan, Lingling Lu, Chunli Zhao, Huanying Zhao, Hui Yan. Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model. Neurochemistry international. vol 59. issue 5. 2012-01-12. PMID:21672589. |
reduced pp2a activity and increased phosphorylation of pp2a at y307 (inactive form of pp2a) were observed in pink1-knockdown dopaminergic cells and striatum tissues. |
2012-01-12 |
2023-08-12 |
mouse |
Andreas Ratzka, Olga Baron, Claudia Groth. FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system. PloS one. vol 6. issue 8. 2011-12-30. PMID:21876757. |
in the central nervous system dopaminergic neurons of the substantia nigra and their axonal projections into the striatum progressively degenerate in parkinson's disease. |
2011-12-30 |
2023-08-12 |
mouse |
Gennaro Giordano, Toby B Cole, Clement E Furlong, Lucio G Cost. Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? Toxicology and applied pharmacology. vol 256. issue 3. 2011-12-27. PMID:21354197. |
these results indicate that pon2 is expressed in the brain, and that higher levels are found in dopaminergic regions such as the striatum, suggesting that this enzyme may provide protection against oxidative stress-mediated neurotoxicity. |
2011-12-27 |
2023-08-12 |
mouse |
Toshio Obata, Masahiro Aomin. Protective effect of tamoxifen, a synthetic non-steroidal antiestrogen, on phenelzine and 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxyl radical generation in rat striatum. Research communications in molecular pathology and pharmacology. vol 122-123. issue 1-6. 2011-12-13. PMID:22032091. |
the present study examined whether tamoxifen could suppress antidepressant drug phenelzine can increase an active dopaminergic neurotoxin, 1-methyl-4-phenylpyridinium ion (mpp+)-induced hydroxyl radical (*oh) generation in the extracellular fluid of rat striatum, using in vivo microdialysis system. |
2011-12-13 |
2023-08-12 |
rat |
Ahmed Hasbi, Brian F O'Dowd, Susan R Georg. Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance. Molecular brain. vol 4. 2011-11-30. PMID:21663703. |
dopamine d1 and d2 receptors are the most abundant dopaminergic receptors in the striatum, and although a clear segregation between the pathways expressing these two receptors has been reported in certain subregions, the presence of d1-d2 receptor heteromers within a unique subset of neurons, forming a novel signaling transducing functional entity has been shown. |
2011-11-30 |
2023-08-12 |
Not clear |
Eun-Yee Jung, Insop Shi. Differential DAergic Control of D1 and D2 Receptor Agonist Over Locomotor Activity and GABA Level in the Striatum. Experimental neurobiology. vol 20. issue 3. 2011-11-23. PMID:22110374. |
the striatum, which is the major input station of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. |
2011-11-23 |
2023-08-12 |
mouse |
Roshan Cool. Dopaminergic control of the striatum for high-level cognition. Current opinion in neurobiology. vol 21. issue 3. 2011-11-21. PMID:21531543. |
dopaminergic control of the striatum for high-level cognition. |
2011-11-21 |
2023-08-12 |
Not clear |
Anne M Landau, M Mallar Chakravarty, Campbell M Clark, Athanasios P Zis, Doris J Doude. Electroconvulsive therapy alters dopamine signaling in the striatum of non-human primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20944554. |
the aim of this work was to explore the impact of ect on dopaminergic function in the striatum of non-human primates. |
2011-11-14 |
2023-08-12 |
human |
Jennifer T Coull, Ruey-Kuang Cheng, Warren H Mec. Neuroanatomical and neurochemical substrates of timing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 1. 2011-11-10. PMID:20668434. |
among these, the dorsal striatum of the bg and, more specifically, its ascending nigrostriatal dopaminergic pathway seems to be the most crucial of these regions, as shown by converging functional neuroimaging, neuropsychological, and psychopharmacological investigations in humans, as well as lesion and pharmacological studies in animals. |
2011-11-10 |
2023-08-12 |
Not clear |
Alessandra Bonito-Oliva, Michael Feyder, Gilberto Fison. Deciphering the Actions of Antiparkinsonian and Antipsychotic Drugs on cAMP/DARPP-32 Signaling. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21808606. |
for instance, the loss of dopaminergic input to the striatum, which is the main pathological feature of parkinson's disease, is counteracted by administering the dopamine precursor, l-dopa. |
2011-11-10 |
2023-08-12 |
Not clear |