| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khaled Radad, Rudolf Moldzio, Wolf-Dieter Rausc. Rapamycin protects dopaminergic neurons against rotenone-induced cell death in primary mesencephalic cell culture. Folia neuropathologica. vol 53. issue 3. 2016-12-13. PMID:26443316. |
parkinson's disease is the most common movement disorder, characterized by a progressive and extensive loss of dopaminergic neurons in the substantia nigra pars compacta and their terminals in the striatum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Miguel Mejias, Jing Yu, Scott Mackey, Katie Dinelle, Vesna Sossi, Doris J Doude. Interpreting DTBZ binding data in rodent: Inherent variability and compensation. Synapse (New York, N.Y.). vol 70. issue 4. 2016-12-13. PMID:26749375. |
[11c]-dihydrotetrabenazine (dtbz) positron emission tomography was used to evaluate the vesicular monoamine transporter type 2 as an index of dopaminergic function in the striatum of adult sprague-dawley rats obtained from two different animal sources (charles river laboratories [cr] or ubc's animal care centre [acc]) and later submitted to two different unilateral lesions of the nigro-striatal pathway. |
2016-12-13 |
2023-08-13 |
rat |
| Douglas Teixeira Leffa, Andressa de Souza, Vanessa Leal Scarabelot, Liciane Fernandes Medeiros, Carla de Oliveira, Eugenio Horacio Grevet, Wolnei Caumo, Diogo Onofre de Souza, Luis Augusto Paim Rohde, Iraci L S Torre. Transcranial direct current stimulation improves short-term memory in an animal model of attention-deficit/hyperactivity disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 2. 2016-12-13. PMID:26792443. |
these findings suggest that tdcs on the frontal cortex might be able to improve stm deficits present in shr, which is potentially related to dopaminergic neurotransmission in the hippocampus and striatum of those animals. |
2016-12-13 |
2023-08-13 |
rat |
| Juan Camilo Jurado-Coronel, Marco Avila-Rodriguez, Francisco Capani, Janneth Gonzalez, Valentina Echeverria Moran, George E Barret. Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease. Current pharmaceutical design. vol 22. issue 10. 2016-12-13. PMID:26972289. |
parkinson's disease (pd) is a relatively common disorder of the central nervous system (cns), whose etiology is characterized by a selective and progressive degeneration of dopaminergic neurons, and the presence of lewy bodies in the pars compacta of the substantia nigra, and gaping dopamine depletion in the striatum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Dimitri Ryczko, Jackson J Cone, Michael H Alpert, Laurent Goetz, François Auclair, Catherine Dubé, Martin Parent, Mitchell F Roitman, Simon Alford, Réjean Dubu. A descending dopamine pathway conserved from basal vertebrates to mammals. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 17. 2016-12-13. PMID:27071118. |
in rats, some dopamine neurons projecting to the striatum also innervated the pedunculopontine nucleus, a known locomotor center, and stimulation of the dopaminergic region evoked pedunculopontine dopamine release in vivo. |
2016-12-13 |
2023-08-13 |
human |
| Xu Jing, Xinbing Wei, Manru Ren, Lingtian Wang, Xiumei Zhang, Haiyan Lo. Neuroprotective Effects of Tanshinone I Against 6-OHDA-Induced Oxidative Stress in Cellular and Mouse Model of Parkinson's Disease Through Upregulating Nrf2. Neurochemical research. vol 41. issue 4. 2016-11-10. PMID:26537816. |
moreover, in the in vivo experiment, t-i treatment significantly attenuated 6-ohda-induced striatal oxidative stress and ameliorated dopaminergic neurotoxicity in 6-ohda-lesioned mice, as evidenced by western blot analysis of tyrosine hydroxylase (th) and th immunostaining of dopaminergic neurons in the substantia nigra and the striatum. |
2016-11-10 |
2023-08-13 |
mouse |
| Milena Pinto, Nadee Nissanka, Susana Peralta, Roberta Brambilla, Francisca Diaz, Carlos T Morae. Pioglitazone ameliorates the phenotype of a novel Parkinson's disease mouse model by reducing neuroinflammation. Molecular neurodegeneration. vol 11. 2016-11-08. PMID:27038906. |
the cause of the motor symptoms is the loss of dopaminergic neurons in the substantia nigra with consequent depletion of dopamine in the striatum. |
2016-11-08 |
2023-08-13 |
mouse |
| Mouna Es-seddiqi, Nicole El Massioui, Nathalie Samson, Bruce L Brown, Valérie Doyèr. The amygdalo-nigrostriatal network is critical for an optimal temporal performance. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 3. 2016-10-27. PMID:26884227. |
we assessed rats having a disconnected ans network, due to contralateral lesions of the medial central nucleus of the amygdala (cem) and dopaminergic afferents to the lateral striatum, as compared to controls (sham and ipsilateral lesions of cem and dopaminergic afferents to ls) in a temporal bisection task. |
2016-10-27 |
2023-08-13 |
rat |
| Filipe C Matheus, Daniel Rial, Joana I Real, Cristina Lemos, Juliana Ben, Gisele O Guaita, Inês R Pita, Ana C Sequeira, Frederico C Pereira, Roger Walz, Reinaldo N Takahashi, Leandro J Bertoglio, Cláudio Da Cunha, Rodrigo A Cunha, Rui D Predige. Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats. Behavioural brain research. vol 301. 2016-10-20. PMID:26707254. |
parkinson's disease (pd) is characterized by motor dysfunction associated with dopaminergic degeneration in the dorsolateral striatum (dls). |
2016-10-20 |
2023-08-13 |
rat |
| Filipe C Matheus, Daniel Rial, Joana I Real, Cristina Lemos, Juliana Ben, Gisele O Guaita, Inês R Pita, Ana C Sequeira, Frederico C Pereira, Roger Walz, Reinaldo N Takahashi, Leandro J Bertoglio, Cláudio Da Cunha, Rodrigo A Cunha, Rui D Predige. Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats. Behavioural brain research. vol 301. 2016-10-20. PMID:26707254. |
the bilateral injection of 6-ohda (20μg/hemisphere) in the dls caused a marked loss of dopaminergic neurons in the substantia nigra (>80%) and decreased monoamine levels in the striatum and pfc, accompanied by motor deficits evaluated after 21 days in the open field and accelerated rotarod. |
2016-10-20 |
2023-08-13 |
rat |
| Manuela Meireles, Luís M Rodríguez-Alcalá, Cláudia Marques, Sónia Norberto, Joana Freitas, Iva Fernandes, Nuno Mateus, Ana Gomes, Ana Faria, Conceição Calha. Effect of chronic consumption of blackberry extract on high-fat induced obesity in rats and its correlation with metabolic and brain outcomes. Food & function. vol 7. issue 1. 2016-10-17. PMID:26462860. |
be decreased levels of bdnf and also interacted with the dopaminergic system, increasing dopamine turnover in the striatum, and reverting dopamine content induced by a high-fat diet in the prefrontal cortex. |
2016-10-17 |
2023-08-13 |
rat |
| Peter Manza, Sheng Zhang, Chiang-Shan R Li, Hoi-Chung Leun. Resting-state functional connectivity of the striatum in early-stage Parkinson's disease: Cognitive decline and motor symptomatology. Human brain mapping. vol 37. issue 2. 2016-10-17. PMID:26566885. |
parkinson's disease is a neurodegenerative disorder characterized by changes to dopaminergic function in the striatum and a range of cognitive and motor deficits. |
2016-10-17 |
2023-08-13 |
Not clear |
| Yevgenia Kozorovitskiy, Rui Peixoto, Wengang Wang, Arpiar Saunders, Bernardo L Sabatin. Neuromodulation of excitatory synaptogenesis in striatal development. eLife. vol 4. 2016-10-11. PMID:26551563. |
we examined whether dopaminergic neuromodulation regulates activity-dependent glutamatergic synapse formation in the developing striatum. |
2016-10-11 |
2023-08-13 |
Not clear |
| Daniela Vitucci, Annabella Di Giorgio, Francesco Napolitano, Barbara Pelosi, Giuseppe Blasi, Francesco Errico, Maria Teresa Attrotto, Barbara Gelao, Leonardo Fazio, Paolo Taurisano, Anna Di Maio, Valentina Marsili, Massimo Pasqualetti, Alessandro Bertolino, Alessandro Usiell. Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26228524. |
rasd2 is a thyroid hormone target gene, which encodes for a gtp-binding protein enriched in the striatum where, among other functions, it modulates dopaminergic neurotransmission. |
2016-10-06 |
2023-08-13 |
mouse |
| Stefania Righi, Luca Galli, Marco Paganini, Elisabetta Bertini, Maria Pia Viggiano, Silvia Piacentin. Time perception impairment in early-to-moderate stages of Huntington's disease is related to memory deficits. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 37. issue 1. 2016-10-05. PMID:26298827. |
huntington's disease (hd) primarily affects striatum and prefrontal dopaminergic circuits which are fundamental neural correlates of the timekeeping mechanism. |
2016-10-05 |
2023-08-13 |
Not clear |
| Miriam Kannebley Frank, Marco Tulio de Mello, Kil Sun Lee, Paulo Daubian-Nosé, Sergio Tufik, Andrea Maculano Esteve. Sleep-related movement disorder symptoms in SHR are attenuated by physical exercise and an angiotensin-converting enzyme inhibitor. Physiology & behavior. vol 154. 2016-09-30. PMID:26650246. |
dopaminergic receptors, dopamine transporter and tyrosine hydroxylase levels at the striatum were evaluated by western blotting. |
2016-09-30 |
2023-08-13 |
rat |
| Annmarie Ramkissoon, Peter G Well. Methamphetamine oxidative stress, neurotoxicity, and functional deficits are modulated by nuclear factor-E2-related factor 2. Free radical biology & medicine. vol 89. 2016-09-22. PMID:26427884. |
multiple-day dosing with meth enhanced dna oxidation and decreased tyrosine hydroxylase and dopamine transporter staining in the striatum, indicating dopaminergic nerve terminal toxicity, which was more severe in -/- mice, as were deficits in motor coordination and olfactory discrimination. |
2016-09-22 |
2023-08-13 |
mouse |
| Juliane Mehlan, Hans Brosig, Oliver Schmitt, Eilhard Mix, Andreas Wree, Alexander Hawlitschk. Intrastriatal injection of botulinum neurotoxin-A is not cytotoxic in rat brain - A histological and stereological analysis. Brain research. vol 1630. 2016-09-19. PMID:26562665. |
parkinson's disease (pd) is caused by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta, resulting in a deficiency of dopamine in the striatum and an increased release of acetylcholine by tonically active interneurons. |
2016-09-19 |
2023-08-13 |
rat |
| Jessica A Kauhausen, Lachlan H Thompson, Clare L Paris. Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian mice. Molecular and cellular neurosciences. vol 69. 2016-09-12. PMID:26463051. |
simultaneous homotopic transplantation of dopaminergic progenitors, into the ventral midbrain of chabc treated pd mice, had no effect on graft survival but resulted in enhanced axonal growth along the nigrostriatal pathway and reinnervation of the striatum, compared to control grafted mice. |
2016-09-12 |
2023-08-13 |
mouse |
| Vito Di Maio, Francesco Ventriglia, Silvia Santill. A model of dopamine modulated glutamatergic synapse. Bio Systems. vol 136. 2016-09-07. PMID:26001676. |
when dopaminergic neurons make synapses on spiny neurons of the striatum nucleus, they tune the responsiveness of glutamatergic synapses by means of the dopamine d1 and d2 receptors. |
2016-09-07 |
2023-08-13 |
Not clear |