| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudia M García-Peña, Minkyung Kim, Daniela Frade-Pérez, Daniela Avila-González, Elisa Téllez, Grant S Mastick, Elisa Tamariz, Alfredo Varela-Echavarrí. Ascending midbrain dopaminergic axons require descending GAD65 axon fascicles for normal pathfinding. Frontiers in neuroanatomy. vol 8. 2014-06-13. PMID:24926237. |
we observed in mouse and rat embryos that midbrain dopaminergic axons ascend in close apposition to descending gad65-positive axon bundles throughout their trajectory to the striatum. |
2014-06-13 |
2023-08-13 |
mouse |
| Xiaofeng Xu, Naidong Wang, Huamin Xu, Anmu Xie, Hong Jiang, Junxia Xi. Fibroblast growth factor 20 polymorphism in sporadic Parkinson's disease in Northern Han Chinese. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 20. issue 11. 2014-06-06. PMID:23938014. |
fibroblast growth factor (fgf) 20 is a neurotrophic factor that exerts strong neurotrophic properties in the brain and could significantly enhance the survival of rat midbrain dopaminergic neurons. |
2014-06-06 |
2023-08-12 |
rat |
| Rami R Ajjuri, Janis M O'Donnel. Novel whole-tissue quantitative assay of nitric oxide levels in Drosophila neuroinflammatory response. Journal of visualized experiments : JoVE. issue 82. 2014-06-05. PMID:24335747. |
for example, loss of dopaminergic neurons in the midbrain, a hallmark of pd, is accelerated by the excessive activation of the inflammatory response. |
2014-06-05 |
2023-08-12 |
drosophila_melanogaster |
| Anke Zlotnik, Björn Spitta. GDNF fails to inhibit LPS-mediated activation of mouse microglia. Journal of neuroimmunology. vol 270. issue 1-2. 2014-06-05. PMID:24655425. |
gdnf is a potent neuroprotective factor for midbrain dopaminergic (mda) neurons. |
2014-06-05 |
2023-08-12 |
mouse |
| Kazuto Kobayashi, Ryoji Fukabori, Kayo Nishizaw. Neural circuit mechanism for learning dependent on dopamine transmission: roles of striatal direct and indirect pathways in sensory discrimination. Advances in pharmacology (San Diego, Calif.). vol 68. 2014-05-29. PMID:24054143. |
the striatum receives excitatory inputs from many cortical areas and the thalamic nuclei and dopaminergic inputs from the ventral midbrain and projects to the output nuclei through direct and indirect pathways. |
2014-05-29 |
2023-08-12 |
mouse |
| Jonathan M Lovell, Judith Mylius, Henning Scheich, Michael Brosc. Hearing in action; auditory properties of neurons in the red nucleus of alert primates. Frontiers in neuroscience. vol 8. 2014-05-26. PMID:24860417. |
the response of neurons in the red nucleus pars magnocellularis (rnm) to both tone bursts and electrical stimulation were observed in three cynomolgus monkeys (macaca fascicularis), in a series of studies primarily designed to characterize the influence of the dopaminergic ventral midbrain on auditory processing. |
2014-05-26 |
2023-08-13 |
monkey |
| Linghai Yang, Merle L Gilbert, Ruimao Zheng, G Stanley McKnigh. Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695708. |
dopaminergic inputs from the midbrain modulate msn excitability through pathways that involve camp and protein kinase a (pka), but the physiological role of specific pka isoforms in msn neurons remains poorly understood. |
2014-05-22 |
2023-08-13 |
mouse |
| María Eugenia Pallarés, Carlos Javier Baier, Ezequiela Adrover, Melisa Carolina Monteleone, Marcela Adriana Brocco, Marta Cristina Antonell. Age-dependent effects of prenatal stress on the corticolimbic dopaminergic system development in the rat male offspring. Neurochemical research. vol 38. issue 11. 2014-05-21. PMID:24013886. |
we have previously demonstrated that prenatal stress (ps) exerts an impairment of midbrain dopaminergic (da) system metabolism especially after puberty, suggesting a particular sensitivity of da development to variations in gonadal hormonal peaks. |
2014-05-21 |
2023-08-12 |
rat |
| Daniel Dautan, Icnelia Huerta-Ocampo, Ilana B Witten, Karl Deisseroth, J Paul Bolam, Todor Gerdjikov, Juan Mena-Segovi. A major external source of cholinergic innervation of the striatum and nucleus accumbens originates in the brainstem. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 13. 2014-05-19. PMID:24671996. |
furthermore, transynaptic gene activation and conventional double retrograde labeling suggest that ldt neurons that innervate the nucleus accumbens also send collaterals to the thalamus and the dopaminergic midbrain, thus providing both direct and indirect projections, to the striatal complex. |
2014-05-19 |
2023-08-12 |
rat |
| Ruben K Dagda, Irene Pien, Ruth Wang, Jianhui Zhu, Kent Z Q Wang, Jason Callio, Tania Das Banerjee, Raul Y Dagda, Charleen T Ch. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24151868. |
over-expression of wild-type pink1, but not a catalytically inactive form of pink1(k219m), promoted neurite outgrowth in sh-sy5y cells and increased dendritic lengths in primary cortical and midbrain dopaminergic neurons. |
2014-05-14 |
2023-08-12 |
Not clear |
| Gina Lungu, George Stoica, Andy Ambru. MicroRNA profiling and the role of microRNA-132 in neurodegeneration using a rat model. Neuroscience letters. vol 553. 2014-05-08. PMID:23973300. |
next we analyzed one of the known downstream targets of mir-132, nuclear receptor related 1 protein (nurr1), which is essential in neurogenesis of midbrain dopaminergic neurons. |
2014-05-08 |
2023-08-12 |
rat |
| Gina Lungu, George Stoica, Andy Ambru. MicroRNA profiling and the role of microRNA-132 in neurodegeneration using a rat model. Neuroscience letters. vol 553. 2014-05-08. PMID:23973300. |
taken together, our findings suggest that mir-132 can regulate nurr1 levels and might influence the development and function of midbrain dopaminergic neurons. |
2014-05-08 |
2023-08-12 |
rat |
| Andreas Hermann, Kai F Loewenbrück, Änne Boldt, Christiane Fiedler, Martina Maisel, Joanna Kalucka, Johannes Schwarz, Georg Breier, Alexander Storc. Lack of vascular endothelial growth factor receptor-2/Flk1 signaling does not affect substantia nigra development. Neuroscience letters. vol 553. 2014-05-08. PMID:23994060. |
lack of hypoxia-inducible factor-1α (hif1α) impairs midbrain dopaminergic neurogenesis which could be rescued by vascular endothelial growth factor (vegf) via vegfr-2 signaling. |
2014-05-08 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. |
2014-05-02 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
the results showed that cno selectively activated midbrain dopaminergic neurons and induced hyperactivity in a dose-dependent manner, supporting the idea that these neurons play an important role in regulating motor activity. |
2014-05-02 |
2023-08-12 |
mouse |
| William Omar Contreras Lopez, Guido Nikkhah, Ulf D Kahlert, Donata Maciaczyk, Tomasz Bogiel, Sven Moellers, Elisabeth Schültke, Máté Döbrössy, Jaroslaw Maciaczy. Clinical neurotransplantation protocol for Huntington's and Parkinson's disease. Restorative neurology and neuroscience. vol 31. issue 5. 2014-04-22. PMID:23777636. |
the concept of transplantation of neuronal cells to treat huntington's and parkinson's diseases is based on the proven principle that dopaminergic and gaba-ergic progenitor neurons (from the human developing ventral mesencephalon and whole ganglionic eminence) can survive, differentiate and functionally integrate into an allogenic host brain. |
2014-04-22 |
2023-08-12 |
human |
| Daniel J Foster, Patrick R Gentry, Jose E Lizardi-Ortiz, Thomas M Bridges, Michael R Wood, Colleen M Niswender, David Sulzer, Craig W Lindsley, Zixiu Xiang, P Jeffrey Con. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 9. 2014-04-22. PMID:24573284. |
of the five muscarinic receptor subtypes, the m5 receptor is the only one detectable in midbrain dopaminergic neurons, making it an attractive potential therapeutic target for treating disorders in which dopaminergic signaling is disrupted. |
2014-04-22 |
2023-08-12 |
mouse |
| Victoria B Gradin, Gordon Waiter, Akira O'Connor, Liana Romaniuk, Catriona Stickle, Keith Matthews, Jeremy Hall, J Douglas Steel. Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia. Psychiatry research. vol 211. issue 2. 2014-04-21. PMID:23146249. |
furthermore, we investigated functional connectivity between the dopaminergic midbrain, a key region for the processing of reinforcers, and other brain regions. |
2014-04-21 |
2023-08-12 |
Not clear |
| M A Fahim, S Shehab, A Nemmar, A Adem, S Dhanasekaran, M Y Hasa. Daily subacute paraquat exposure decreases muscle function and substantia nigra dopamine level. Physiological research. vol 62. issue 3. 2014-04-21. PMID:23489189. |
dopamine concentrations in the ventral mesencephalon were measured by high performance liquid chromatography and the number of dopaminergic neurons in substantia nigra pars compacta was estimated by tyrosine hydroxylase immunohistochemistry. |
2014-04-21 |
2023-08-12 |
rat |
| Michael C Chen, Huan Yu, Zhi-Li Huang, Jun L. Rapid eye movement sleep behavior disorder. Current opinion in neurobiology. vol 23. issue 5. 2014-04-16. PMID:23518139. |
rbd can precede the onset of pd by decades, suggesting an underlying pathology that can progressively afflict rem atonia and midbrain dopaminergic centers. |
2014-04-16 |
2023-08-12 |
Not clear |