| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Kurowska, P Brundin, M E Schwab, J-Y L. Intracellular Nogo-A facilitates initiation of neurite formation in mouse midbrain neurons in vitro. Neuroscience. vol 256. 2014-08-27. PMID:24157929. |
cultured midbrain (dopaminergic) neurons from nogo-a knock-out mice exhibited decreased numbers of neurites and branches when compared with neurons from wild-type (wt) mice. |
2014-08-27 |
2023-08-12 |
mouse |
| Z Kurowska, P Brundin, M E Schwab, J-Y L. Intracellular Nogo-A facilitates initiation of neurite formation in mouse midbrain neurons in vitro. Neuroscience. vol 256. 2014-08-27. PMID:24157929. |
these results indicate that during maturation of cultured midbrain (dopaminergic) neurons, intracellular nogo-a supports neurite growth initiation and branch formation. |
2014-08-27 |
2023-08-12 |
mouse |
| Takashi Tanida, Ken Tasaka, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Michiko Saito, Shigehisa Kawata, Megumi Danjo, Junko Tokumoto, Youhei Mantani, Daichi Nagahara, Yoshiaki Tabuchi, Toshifumi Yokoyama, Hiroshi Kitagawa, Mitsuhiro Kawata, Nobuhiko Hosh. Fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin transactivates aryl hydrocarbon receptor-responsive element III in the tyrosine hydroxylase immunoreactive neurons of the mouse midbrain. Journal of applied toxicology : JAT. vol 34. issue 2. 2014-08-26. PMID:23296914. |
fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. |
2014-08-26 |
2023-08-12 |
mouse |
| Takashi Tanida, Ken Tasaka, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Michiko Saito, Shigehisa Kawata, Megumi Danjo, Junko Tokumoto, Youhei Mantani, Daichi Nagahara, Yoshiaki Tabuchi, Toshifumi Yokoyama, Hiroshi Kitagawa, Mitsuhiro Kawata, Nobuhiko Hosh. Fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin transactivates aryl hydrocarbon receptor-responsive element III in the tyrosine hydroxylase immunoreactive neurons of the mouse midbrain. Journal of applied toxicology : JAT. vol 34. issue 2. 2014-08-26. PMID:23296914. |
to provide in vivo evidence, we investigated whether 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) could regulate ahre-iii transcriptional activity in midbrain dopaminergic neurons. |
2014-08-26 |
2023-08-12 |
mouse |
| Biswarup Ghosh, Chen Zhang, George M Smit. Bridging between transplantation therapy and neurotrophic factors in Parkinson's disease. Frontiers in bioscience (Elite edition). vol 6. 2014-08-25. PMID:24896204. |
transplantation of embryonic ventral mesencephalon (vm) dopaminergic neurons has shown promise in animal studies, but similar transplant procedures have shown limited success in clinical trials. |
2014-08-25 |
2023-08-13 |
Not clear |
| Biswarup Ghosh, Chen Zhang, George M Smit. Bridging between transplantation therapy and neurotrophic factors in Parkinson's disease. Frontiers in bioscience (Elite edition). vol 6. 2014-08-25. PMID:24896204. |
with increased understanding of growth and guidance molecule effecting dopaminergic neurons, it may be feasible to place transplants in the damaged substantia nigra and direct the growth of axons into target regions to reconstruction of midbrain dopamine (da) circuitry. |
2014-08-25 |
2023-08-13 |
Not clear |
| Doan V Khanh, Yun-Hee Choi, Sang Hyun Moh, Ann W Kinyua, Ki Woo Ki. Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system. Frontiers in psychology. vol 5. 2014-08-22. PMID:25147530. |
recent studies have indicated the midbrain dopaminergic neurons as a potential site for leptin' and insulin's actions on mediating the feeding behaviors and therefore affecting the energy balance. |
2014-08-22 |
2023-08-13 |
Not clear |
| Doan V Khanh, Yun-Hee Choi, Sang Hyun Moh, Ann W Kinyua, Ki Woo Ki. Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system. Frontiers in psychology. vol 5. 2014-08-22. PMID:25147530. |
this review therefore describes the convergence of energy regulation and reward system, particularly focusing on leptin and insulin signaling in the midbrain dopaminergic neurons. |
2014-08-22 |
2023-08-13 |
Not clear |
| Kanwar Virdee, Simon McArthur, Frédéric Brischoux, Daniele Caprioli, Mark A Ungless, Trevor W Robbins, Jeffrey W Dalley, Glenda E Gillie. Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 2. 2014-08-21. PMID:23929547. |
we demonstrated previously that antenatal glucocorticoid treatment (agt, gestational days 16-19) altered the size and organization of the adult rat midbrain dopaminergic (da) populations. |
2014-08-21 |
2023-08-12 |
rat |
| Daniel C Berwick, Kirsten Harve. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24115276. |
recent work has established a critical role for these pathways in brain development, especially of midbrain dopaminergic neurones. |
2014-08-21 |
2023-08-12 |
Not clear |
| Daniel C Berwick, Kirsten Harve. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24115276. |
this debilitating disease is characterized by the progressive loss of a subset of midbrain dopaminergic neurones in the substantia nigra leading to typical extrapyramidal motor symptoms. |
2014-08-21 |
2023-08-12 |
Not clear |
| Milan Joksimovic, Rajeshwar Awatraman. Wnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24287202. |
loss of midbrain dopaminergic (mda) neurons underlies the motor symptoms of parkinson's disease. |
2014-08-21 |
2023-08-12 |
Not clear |
| Ernest Arena. Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24431302. |
wnt signaling regulates multiple cellular functions and cell systems, including the development and maintenance of midbrain dopaminergic (mda) neurons. |
2014-08-21 |
2023-08-12 |
Not clear |
| Francesca L'Episcopo, Cataldo Tirolo, Salvo Caniglia, Nuccio Testa, Maria Concetta Morale, Maria Francesca Serapide, Stefano Pluchino, Bianca Marchett. Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24431301. |
accumulating evidence points to a dysregulation of wnt signaling in major neurodegenerative pathologies including parkinson's disease (pd), a common neurodegenerative disorder characterized by the progressive loss of midbrain dopaminergic (mda) neurons and deregulated activation of astrocytes and microglia. |
2014-08-21 |
2023-08-12 |
Not clear |
| Angela Anderegg, Hsin-Pin Lin, Jun-An Chen, Giuliana Caronia-Brown, Natalya Cherepanova, Beth Yun, Milan Joksimovic, Jason Rock, Brian D Harfe, Randy Johnson, Rajeshwar Awatraman. An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. PLoS genetics. vol 9. issue 12. 2014-08-20. PMID:24348261. |
an lmx1b-mir135a2 regulatory circuit modulates wnt1/wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. |
2014-08-20 |
2023-08-12 |
Not clear |
| Sunayana B Banerjee, Brian G Dias, David Crews, Elizabeth Adkins-Rega. Newly paired zebra finches have higher dopamine levels and immediate early gene Fos expression in dopaminergic neurons. The European journal of neuroscience. vol 38. issue 12. 2014-08-15. PMID:24329731. |
in the present study, we sought to understand the specific contribution to pair formation in zebra finches of the mesolimbic dopaminergic pathway that projects from the midbrain ventral tegmental area to the nucleus accumbens. |
2014-08-15 |
2023-08-12 |
Not clear |
| Kai-Hsiang Kang, Horng-Hui Liou, Mann-Jen Hour, Houng-Chi Liou, Wen-Mei F. Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. Neuropharmacology. vol 73. 2014-08-13. PMID:23800665. |
in this study, we investigated the effect of the pharmacological inhibition of 5-lipoxygenase on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)/mpp(+)-induced dopaminergic neuronal death in midbrain neuron-glia co-cultures and in mice. |
2014-08-13 |
2023-08-12 |
mouse |
| Kai-Hsiang Kang, Horng-Hui Liou, Mann-Jen Hour, Houng-Chi Liou, Wen-Mei F. Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. Neuropharmacology. vol 73. 2014-08-13. PMID:23800665. |
mk-886, a specific inhibitor of 5-lox activating protein (flap), significantly increased [(3)h]-dopamine uptake, a functional indicator of the integrity of dopaminergic neurons, in midbrain cultures or the sh-sy5y human dopaminergic cell line following mpp(+) treatment. |
2014-08-13 |
2023-08-12 |
mouse |
| Pia Jensen, Michel Heimberg, Angelique D Ducray, Hans R Widmer, Morten Meye. Expression of trefoil factor 1 in the developing and adult rat ventral mesencephalon. PloS one. vol 8. issue 10. 2014-08-02. PMID:24116124. |
in conclusion, we show for the first time that distinct subpopulations of midbrain dopaminergic neurons express tff1, and that this expression pattern is altered in a rat model of parkinson's disease. |
2014-08-02 |
2023-08-12 |
rat |
| Mickael Decressac, Nikolaos Volakakis, Anders Björklund, Thomas Perlman. NURR1 in Parkinson disease--from pathogenesis to therapeutic potential. Nature reviews. Neurology. vol 9. issue 11. 2014-07-28. PMID:24126627. |
in parkinson disease (pd), affected midbrain dopamine (da) neurons lose specific dopaminergic properties before the neurons die. |
2014-07-28 |
2023-08-12 |
Not clear |