| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Göbel, C Er. [Neurological disorders and glaucoma - an overview]. Klinische Monatsblatter fur Augenheilkunde. vol 231. issue 2. 2014-11-05. PMID:24532400. |
parkinson's disease is characterised by a loss of dopaminergic neurons in the basal ganglia-substantia nigra pars compacta of the midbrain. |
2014-11-05 |
2023-08-12 |
Not clear |
| M O Guloglu, A Larsen, P Brundi. Adipocytes derived from PA6 cells reliably promote the differentiation of dopaminergic neurons from human embryonic stem cells. Journal of neuroscience research. vol 92. issue 5. 2014-11-04. PMID:24482287. |
furthermore, we report that the coculture of human embryonic stem cells with pa6-derived adipocytes reliably induces their differentiation into midbrain dopaminergic neurons. |
2014-11-04 |
2023-08-12 |
mouse |
| M J Tobia, R Guo, U Schwarze, W Boehmer, J Gläscher, B Finckh, A Marschner, C Büchel, K Obermayer, T Somme. Neural systems for choice and valuation with counterfactual learning signals. NeuroImage. vol 89. 2014-10-29. PMID:24321554. |
the depletion procedure revealed significantly different neural responses to expected value in the vmpfc, caudate, and dopaminergic midbrain in the vicinity of the substantia nigra (sn). |
2014-10-29 |
2023-08-12 |
human |
| Matteo Colomb. Deep and beautiful. The reward prediction error hypothesis of dopamine. Studies in history and philosophy of biological and biomedical sciences. vol 45. 2014-10-22. PMID:24252364. |
according to the reward-prediction error hypothesis (rpeh) of dopamine, the phasic activity of dopaminergic neurons in the midbrain signals a discrepancy between the predicted and currently experienced reward of a particular event. |
2014-10-22 |
2023-08-12 |
Not clear |
| Alan D Pickering, Francesca Pesol. Modeling dopaminergic and other processes involved in learning from reward prediction error: contributions from an individual differences perspective. Frontiers in human neuroscience. vol 8. 2014-10-17. PMID:25324752. |
in particular, variations in the strength of connections carrying excitatory reward drive inputs to midbrain dopaminergic cells were considered plausible candidates, along with variations in a parameter which scales the effects of dopamine cell firing bursts on synaptic modification in ventral striatum. |
2014-10-17 |
2023-08-13 |
Not clear |
| Marielle Zoetmulder, Heidi B Biernat, Miki Nikolic, Lise Korbo, Lars Friberg, Poul J Jennu. Prepulse inhibition is associated with attention, processing speed, and 123I-FP-CIT SPECT in Parkinson's disease. Journal of Parkinson's disease. vol 4. issue 1. 2014-10-14. PMID:24366928. |
prepulse inhibition is dramatically altered in basal ganglia disorders associated with dysfunction in the midbrain dopaminergic system, and corresponding cognitive information processing deficits such as slowed processing speed. |
2014-10-14 |
2023-08-12 |
Not clear |
| Marielle Zoetmulder, Heidi B Biernat, Miki Nikolic, Lise Korbo, Lars Friberg, Poul J Jennu. Prepulse inhibition is associated with attention, processing speed, and 123I-FP-CIT SPECT in Parkinson's disease. Journal of Parkinson's disease. vol 4. issue 1. 2014-10-14. PMID:24366928. |
parkinson's disease is characterised by the degeneration of the midbrain dopaminergic system and is associated with cognitive dysfunction, including slowed information processing. |
2014-10-14 |
2023-08-12 |
Not clear |
| Aisling M Gavin, Sinéad Walsh, Sean Wyatt, Gerard W O'Keeffe, Aideen M Sulliva. 6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo. Neuroscience letters. vol 561. 2014-10-07. PMID:24373993. |
growth/differentiation factor (gdf)5 and glial cell line-derived neurotrophic factor (gdnf) are neurotrophic factors that promote the survival of midbrain dopaminergic neurons in vitro and in vivo. |
2014-10-07 |
2023-08-12 |
rat |
| B L Mason, Q Wang, J M Zigma. The central nervous system sites mediating the orexigenic actions of ghrelin. Annual review of physiology. vol 76. 2014-09-30. PMID:24111557. |
this review discusses those central nervous system sites that have been found to play critical roles in the orexigenic actions of ghrelin, including hypothalamic nuclei, the hippocampus, the amygdala, the caudal brain stem, and midbrain dopaminergic neurons. |
2014-09-30 |
2023-08-12 |
Not clear |
| C Bertram, L Dahan, L W Boorman, S Harris, N Vautrelle, M Leriche, P Redgrave, P G Overto. Cortical regulation of dopaminergic neurons: role of the midbrain superior colliculus. Journal of neurophysiology. vol 111. issue 4. 2014-09-30. PMID:24225541. |
cortical regulation of dopaminergic neurons: role of the midbrain superior colliculus. |
2014-09-30 |
2023-08-12 |
rat |
| Tetsuya Ishii, Koji Et. Fetal stem cell transplantation: Past, present, and future. World journal of stem cells. vol 6. issue 4. 2014-09-26. PMID:25258662. |
although the transplantation of the fetal midbrain substantia nigra and dopaminergic neurons in patients suffering from parkinson's disease is particularly noteworthy, the history of other types of grafts, such as those of the fetal liver, thymus, and pancreas, should be addressed as there are many lessons to be learnt for future stem cell transplantation. |
2014-09-26 |
2023-08-13 |
human |
| Xueyan Pang, Eric M Hogan, Alison Casserly, Guangping Gao, Paul D Gardner, Andrew R Tappe. Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival. Molecular and cellular neurosciences. vol 58. 2014-09-25. PMID:24184162. |
dicer expression is essential for mouse midbrain development and dopaminergic (daergic) neuron maintenance and survival during the early post-natal period. |
2014-09-25 |
2023-08-12 |
mouse |
| Daniel J Chandler, Barry D Waterhouse, Wen-Jun Ga. New perspectives on catecholaminergic regulation of executive circuits: evidence for independent modulation of prefrontal functions by midbrain dopaminergic and noradrenergic neurons. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24904299. |
new perspectives on catecholaminergic regulation of executive circuits: evidence for independent modulation of prefrontal functions by midbrain dopaminergic and noradrenergic neurons. |
2014-09-24 |
2023-08-13 |
Not clear |
| Daniel J Chandler, Barry D Waterhouse, Wen-Jun Ga. New perspectives on catecholaminergic regulation of executive circuits: evidence for independent modulation of prefrontal functions by midbrain dopaminergic and noradrenergic neurons. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24904299. |
midbrain dopaminergic neurons in the ventral tegmental area and noradrenergic neurons in the locus coeruleus are major sources of da and ne to the pfc. |
2014-09-24 |
2023-08-13 |
Not clear |
| Henry H Yi. Action, time and the basal ganglia. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1637. 2014-09-22. PMID:24446506. |
the ability to control the speed of movement is compromised in neurological disorders involving the basal ganglia, a set of subcortical cerebral nuclei that receive prominent dopaminergic projections from the midbrain. |
2014-09-22 |
2023-08-12 |
Not clear |
| D Dardou, S Monlezun, P Foerch, J P Courade, L Cuvelier, M De Ryck, S N Schiffman. A role for Sv2c in basal ganglia functions. Brain research. vol 1507. 2014-09-18. PMID:23458503. |
in sv2c-/- mice, the expression of tyrosine hydroxylase mrna in midbrain dopaminergic neurons was largely and significantly increased and enkephalin mrna expression was significantly decreased in the caudate-putamen and accumbens nucleus. |
2014-09-18 |
2023-08-12 |
mouse |
| Ulrike Stadlbauer, Elisabeth Weber, Wolfgang Langhans, Urs Meye. The Y2 receptor agonist PYY(3-36) increases the behavioural response to novelty and acute dopaminergic drug challenge in mice. The international journal of neuropsychopharmacology. vol 17. issue 3. 2014-09-17. PMID:24131590. |
pyy(3-36) administration did not affect activity of midbrain dopaminergic cells as evaluated by double immuno-enzyme staining of the neuronal early gene product c-fos with tyrosine hydroxylase. |
2014-09-17 |
2023-08-12 |
mouse |
| T Karayannis, E Au, J C Patel, I Kruglikov, S Markx, R Delorme, D Héron, D Salomon, J Glessner, S Restituito, A Gordon, L Rodriguez-Murillo, N C Roy, J A Gogos, B Rudy, M E Rice, M Karayiorgou, H Hakonarson, B Keren, G Huguet, T Bourgeron, C Hoeffer, R W Tsien, E Peles, G Fishel. Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. vol 511. issue 7508. 2014-09-17. PMID:24870235. |
paradoxically, the loss of cntnap4 augments midbrain dopaminergic release in the nucleus accumbens. |
2014-09-17 |
2023-08-13 |
mouse |
| Y Yabuki, Y Ohizumi, A Yokosuka, Y Mimaki, K Fukunag. Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice. Neuroscience. vol 259. 2014-09-11. PMID:24316474. |
nonetheless, nobiletin treatment did not block loss of dopaminergic neurons seen in the mptp-treated mouse midbrain, nor did it rescue decreased tyrosine hydroxylase (th) protein levels seen in the striatum or hippocampal ca1 region of these mice. |
2014-09-11 |
2023-08-12 |
mouse |
| Han-Seop Kim, Janghwan Kim, Yeonju Jo, Daejong Jeon, Yee Sook Ch. Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors. Stem cell research. vol 12. issue 1. 2014-09-10. PMID:24145188. |
direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors. |
2014-09-10 |
2023-08-12 |
mouse |