| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Han-Seop Kim, Janghwan Kim, Yeonju Jo, Daejong Jeon, Yee Sook Ch. Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors. Stem cell research. vol 12. issue 1. 2014-09-10. PMID:24145188. |
here, we show that mouse fibroblasts can be directly reprogrammed into midbrain dopaminergic neuronal progenitors (dps) by temporal expression of the pluripotency factors and environment containing sonic hedgehog and fibroblast growth factor 8. |
2014-09-10 |
2023-08-12 |
mouse |
| Han-Seop Kim, Janghwan Kim, Yeonju Jo, Daejong Jeon, Yee Sook Ch. Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors. Stem cell research. vol 12. issue 1. 2014-09-10. PMID:24145188. |
we confirmed the functionality of the idps by showing that the dopaminergic neurons generated from idps express midbrain markers, release dopamine, and show typical electrophysiological profiles. |
2014-09-10 |
2023-08-12 |
mouse |
| Domingo Afonso-Oramas, Ignacio Cruz-Muros, Javier Castro-Hernández, Josmar Salas-Hernández, Pedro Barroso-Chinea, Sonia García-Hernández, José L Lanciego, Tomás González-Hernánde. Striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons. Frontiers in neuroanatomy. vol 8. 2014-09-10. PMID:25206324. |
striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Domingo Afonso-Oramas, Ignacio Cruz-Muros, Javier Castro-Hernández, Josmar Salas-Hernández, Pedro Barroso-Chinea, Sonia García-Hernández, José L Lanciego, Tomás González-Hernánde. Striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons. Frontiers in neuroanatomy. vol 8. 2014-09-10. PMID:25206324. |
bearing in mind the evidence of changes in the blood flow of basal ganglia in parkinson's disease (pd), and the pivotal role of the dopaminergic mesostriatal pathway in the pathophysiology of this disease, here we studied whether striatal vessels receive inputs from midbrain dopaminergic neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Domingo Afonso-Oramas, Ignacio Cruz-Muros, Javier Castro-Hernández, Josmar Salas-Hernández, Pedro Barroso-Chinea, Sonia García-Hernández, José L Lanciego, Tomás González-Hernánde. Striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons. Frontiers in neuroanatomy. vol 8. 2014-09-10. PMID:25206324. |
the injection of an anterograde neuronal tracer in combination with immunohistochemistry for dopaminergic, vascular and astroglial markers, and dopaminergic lesions, revealed that midbrain dopaminergic axons are in close apposition to striatal vessels and perivascular astrocytes. |
2014-09-10 |
2023-08-13 |
rat |
| Domingo Afonso-Oramas, Ignacio Cruz-Muros, Javier Castro-Hernández, Josmar Salas-Hernández, Pedro Barroso-Chinea, Sonia García-Hernández, José L Lanciego, Tomás González-Hernánde. Striatal vessels receive phosphorylated tyrosine hydroxylase-rich innervation from midbrain dopaminergic neurons. Frontiers in neuroanatomy. vol 8. 2014-09-10. PMID:25206324. |
the presence of phosphorylated th in vessel terminals indicates they are probably the main source of basal th activity in the striatum, and that after activation of midbrain dopaminergic neurons, da release onto vessels precedes that onto neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Chunhua Wang, Chao Jiang, Honghua Yuan, Chenghua Xiao, Dianshuai Ga. Role of calbindin-D28K in estrogen treatment for Parkinson's disease. Neural regeneration research. vol 8. issue 8. 2014-09-10. PMID:25206716. |
immunofluorescence double staining showed that estrogen increased tyrosine hydroxylase and calbindin-d28k expression and co-expression in dopaminergic neurons of midbrain substantia nigra pars compacta of model mice. |
2014-09-10 |
2023-08-13 |
mouse |
| Huifen Shi, Jie Song, Xuming Yan. Zhichan decoction induces differentiation of dopaminergic neurons in Parkinson's disease rats after neural stem cell transplantation. Neural regeneration research. vol 9. issue 9. 2014-09-10. PMID:25206914. |
using high-performance liquid chromatography, we found that dopamine and dopaminergic metabolite (dihydroxyphenylacetic acid and homovanillic acid) content in the midbrain of parkinson's disease rats was increased after neural stem cell transplantation + zhichan decoction, compared with neural stem cell transplantation alone. |
2014-09-10 |
2023-08-13 |
rat |
| Kambiz N Alavian, Sharmin Jeddi, Sahar I Naghipour, Pegah Nabili, Pawel Licznerski, Travis S Tierne. The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed. Journal of biomedical science. vol 21. 2014-09-08. PMID:24685177. |
specific vulnerability and degeneration of the dopaminergic neurons in the substantia nigra pars compacta of the midbrain is the pathological hallmark of parkinson's disease. |
2014-09-08 |
2023-08-12 |
Not clear |
| Kambiz N Alavian, Sharmin Jeddi, Sahar I Naghipour, Pegah Nabili, Pawel Licznerski, Travis S Tierne. The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed. Journal of biomedical science. vol 21. 2014-09-08. PMID:24685177. |
these maintenance transcription factors are closely associated with essential neurophysiological functions and are required ultimately for the long-term survival of the midbrain dopaminergic neurons. |
2014-09-08 |
2023-08-12 |
Not clear |
| Mohammad Kanafi, Debanjana Majumdar, Ramesh Bhonde, Pawan Gupta, Indrani Datt. Midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24477667. |
midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons. |
2014-09-05 |
2023-08-12 |
human |
| Mohammad Kanafi, Debanjana Majumdar, Ramesh Bhonde, Pawan Gupta, Indrani Datt. Midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24477667. |
we hypothesized that midbrain cues might commit dpscs to differentiate to functional dopaminergic cell-type. |
2014-09-05 |
2023-08-12 |
human |
| Mohammad Kanafi, Debanjana Majumdar, Ramesh Bhonde, Pawan Gupta, Indrani Datt. Midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24477667. |
on exposure to midbrain cues (sonic hedgehog, fibroblast growth factor 8 and basic fibroblast growth factor), dpscs showed upregulation of dopaminergic neuron-specific transcription factors nuclear receptor related protein 1 (nurr1), engrailed 1 (en1) and paired-like homeodomain transcription factor 3 (pitx3) as revealed by real-time rt-pcr. |
2014-09-05 |
2023-08-12 |
human |
| Mohammad Kanafi, Debanjana Majumdar, Ramesh Bhonde, Pawan Gupta, Indrani Datt. Midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24477667. |
our data clearly demonstrate for the first time that dpscs in the presence of embryonic midbrain cues show efficient propensity towards functional dopaminergic cell-type. |
2014-09-05 |
2023-08-12 |
human |
| Anna E Creighton, Walter Wilczynsk. Influence of dopamine D2-type receptors on motor behaviors in the green tree frog, Hyla cinerea. Physiology & behavior. vol 127. 2014-09-05. PMID:24480075. |
research supports anatomical conservation of dopaminergic populations in the midbrain across vertebrate species, however, less evidence is available for dopamine receptor distributions. |
2014-09-05 |
2023-08-12 |
Not clear |
| Surjeet Mastwal, Yizhou Ye, Ming Ren, Dennisse V Jimenez, Keri Martinowich, Charles R Gerfen, Kuan Hong Wan. Phasic dopamine neuron activity elicits unique mesofrontal plasticity in adolescence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 29. 2014-09-05. PMID:25031392. |
the mesofrontal dopaminergic circuit, which connects the midbrain motivation center to the cortical executive center, is engaged in control of motivated behaviors. |
2014-09-05 |
2023-08-13 |
mouse |
| Yanina D Alvarez, Jonathan A Fauerbach, Jésica V Pellegrotti, Thomas M Jovin, Elizabeth A Jares-Erijman, Fernando D Stefan. Influence of gold nanoparticles on the kinetics of α-synuclein aggregation. Nano letters. vol 13. issue 12. 2014-09-04. PMID:24219503. |
amyloid aggregates of as in dopaminergic neurons of the midbrain are the hallmark of parkinson's disease (pd). |
2014-09-04 |
2023-08-12 |
Not clear |
| Joel E Beevers, Tara M Caffrey, Richard Wade-Martin. Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease. Biochemical Society transactions. vol 41. issue 6. 2014-08-29. PMID:24256244. |
given the characteristic loss of dopaminergic neurons in the substantia nigra pars compacta of pd patients, ipsc-derived midbrain dopaminergic neurons have been generated to investigate pathogenic mechanisms in this important cell type as a means of modelling pd. |
2014-08-29 |
2023-08-12 |
Not clear |
| Maryam Sarbishegi, Fereshteh Mehraein, Mansooreh Soleiman. Antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats. Iranian biomedical journal. vol 18. issue 1. 2014-08-28. PMID:24375158. |
antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats. |
2014-08-28 |
2023-08-12 |
rat |
| Z Kurowska, P Brundin, M E Schwab, J-Y L. Intracellular Nogo-A facilitates initiation of neurite formation in mouse midbrain neurons in vitro. Neuroscience. vol 256. 2014-08-27. PMID:24157929. |
here we show that nogo-a is present in neurons derived from human midbrain (lund human mesencephalic (luhmes) cell line), as well as in embryonic and postnatal mouse midbrain (dopaminergic) neurons. |
2014-08-27 |
2023-08-12 |
mouse |