| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew C Havrda, Brenton R Paolella, Nora M Ward, Kathryn B Holroy. Behavioral abnormalities and Parkinson's-like histological changes resulting from Id2 inactivation in mice. Disease models & mechanisms. vol 6. issue 3. 2013-10-29. PMID:23264561. |
here, we summarize behavioral, histological and in vitro molecular biological analyses to determine whether midbrain dopaminergic neurons are affected by id2 loss. |
2013-10-29 |
2023-08-12 |
mouse |
| Juliana A Hutter, Allison Martel, Lianne Trigiani, Shawnna G Barrett, C Andrew Chapma. Rewarding stimulation of the lateral hypothalamus induces a dopamine-dependent suppression of synaptic responses in the entorhinal cortex. Behavioural brain research. vol 252. 2013-10-28. PMID:23747609. |
the entorhinal cortex receives inputs from sensory and associational cortices, as well as a substantial input from midbrain dopaminergic neurons. |
2013-10-28 |
2023-08-12 |
rat |
| Yen Yu, Thomas H B FitzGerald, Karl J Fristo. Working memory and anticipatory set modulate midbrain and putamen activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986240. |
based on the known role of dopamine in cognitive flexibility and working memory updating, we hypothesized that differences in anticipatory set would be manifest in the dopaminergic midbrain and striatum. |
2013-10-28 |
2023-08-12 |
human |
| Yen Yu, Thomas H B FitzGerald, Karl J Fristo. Working memory and anticipatory set modulate midbrain and putamen activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986240. |
consistent with our predictions, we identified sustained activation in the dopaminergic midbrain and the striatum, associated with anticipations of high versus low updating probability. |
2013-10-28 |
2023-08-12 |
human |
| Zygmunt Jamrozik, Mariusz Berdynski, Cezary Zekanowski, Anna Baranczyk-Kuzma, Jarosław Sławek, Magdalena Kuzma-Kozakiewicz, Aleksandra Maruszak, Hubert Kwiecinsk. Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration. Annals of clinical and laboratory science. vol 43. issue 2. 2013-10-25. PMID:23694789. |
interactions of transcriptions factors nurr1, pitx3, and en1 are involved in the maturation and survival of adult midbrain dopaminergic neurons during a lifetime. |
2013-10-25 |
2023-08-12 |
Not clear |
| Richard J Karpowicz, Matthew Dunn, David Sulzer, Dalibor Same. APP+, a fluorescent analogue of the neurotoxin MPP+, is a marker of catecholamine neurons in brain tissue, but not a fluorescent false neurotransmitter. ACS chemical neuroscience. vol 4. issue 5. 2013-10-22. PMID:23647019. |
here we report that app+ labels cell bodies of catecholaminergic neurons in the midbrain in a dat- and net-dependent manner, as well as fine dopaminergic axonal processes in the dorsal striatum. |
2013-10-22 |
2023-08-12 |
mouse |
| Martin E Hess, Simon Hess, Kate D Meyer, Linda A W Verhagen, Linda Koch, Hella S Brönneke, Marcelo O Dietrich, Sabine D Jordan, Yogesh Saletore, Olivier Elemento, Bengt F Belgardt, Thomas Franz, Tamas L Horvath, Ulrich Rüther, Samie R Jaffrey, Peter Kloppenburg, Jens C Brünin. The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nature neuroscience. vol 16. issue 8. 2013-10-17. PMID:23817550. |
the fat mass and obesity associated gene (fto) regulates activity of the dopaminergic midbrain circuitry. |
2013-10-17 |
2023-08-12 |
mouse |
| Roberta Russo, Silvia Zucchelli, Marta Codrich, Federica Marcuzzi, Cinzia Verde, Stefano Gustincic. Hemoglobin is present as a canonical α2β2 tetramer in dopaminergic neurons. Biochimica et biophysica acta. vol 1834. issue 9. 2013-09-26. PMID:23685348. |
our results indicate that (i) in mouse dopaminergic cell line stably over-expressing α and β chains, hemoglobin exists as an α2β2 tetramer; (ii) similarly to the over-expressed protein, endogenous hemoglobin forms a tetramer of 64kda; (iii) hemoglobin also forms high molecular weight insoluble aggregates; and (iv) endogenous hemoglobin retains its tetrameric structure in mouse mesencephalon in vivo. |
2013-09-26 |
2023-08-12 |
mouse |
| L Lahti, K Achim, J Partane. Molecular regulation of GABAergic neuron differentiation and diversity in the developing midbrain. Acta physiologica (Oxford, England). vol 207. issue 4. 2013-09-25. PMID:23297792. |
important gabaergic neuron subpopulations are found within the dopaminergic (da) nuclei in the ventral midbrain. |
2013-09-25 |
2023-08-12 |
Not clear |
| Peter Reinhardt, Michael Glatza, Kathrin Hemmer, Yaroslav Tsytsyura, Cora S Thiel, Susanne Höing, Sören Moritz, Juan A Parga, Lydia Wagner, Jan M Bruder, Guangming Wu, Benjamin Schmid, Albrecht Röpke, Jürgen Klingauf, Jens C Schwamborn, Thomas Gasser, Hans R Schöler, Jared Sternecker. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PloS one. vol 8. issue 3. 2013-09-11. PMID:23533608. |
we demonstrate that smnpcs have the potential to clonally and efficiently differentiate into neural tube lineages, including motor neurons (mns) and midbrain dopaminergic neurons (mdans) as well as neural crest lineages, including peripheral neurons and mesenchymal cells. |
2013-09-11 |
2023-08-12 |
human |
| Jan Haaker, Stefano Gaburro, Anupam Sah, Nina Gartmann, Tina B Lonsdorf, Kolja Meier, Nicolas Singewald, Hans-Christian Pape, Fabio Morellini, Raffael Kalisc. Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 26. 2013-09-06. PMID:23754384. |
in humans, ventromedial prefrontal cortex activity is predicted by enhanced resting-state functional coupling of the area with the dopaminergic midbrain during the postextinction consolidation phase. |
2013-09-06 |
2023-08-12 |
mouse |
| Cristiane Latgé, Kátia M S Cabral, Marcius S Almeida, Débora Fogue. (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Biomolecular NMR assignments. vol 7. issue 1. 2013-08-29. PMID:22528768. |
parkinson's disease (pd) is a neurodegenerative disorder that is caused by the death of midbrain dopaminergic neurons. |
2013-08-29 |
2023-08-12 |
human |
| Cristiane Latgé, Kátia M S Cabral, Marcius S Almeida, Débora Fogue. (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Biomolecular NMR assignments. vol 7. issue 1. 2013-08-29. PMID:22528768. |
therefore, search for novel neurotrophic factors (ntf) for midbrain dopaminergic neurons, which could be used in novel therapeutic approaches, is highly wanted. |
2013-08-29 |
2023-08-12 |
human |
| Yan Zhou, Maosheng Sun, Hongjun Li, Min Yan, Zhanlong He, Wenju Wang, Wanpu Wang, Shuaiyao L. Recovery of behavioral symptoms in hemi-parkinsonian rhesus monkeys through combined gene and stem cell therapy. Cytotherapy. vol 15. issue 4. 2013-08-28. PMID:23403361. |
recent studies have demonstrated the respective roles of lim homeobox transcription factor 1, alpha (lmx1a) and neurturin (ntn) in the commitment of embryonic stem cells (escs) to a midbrain dopaminergic neuronal fate and the commitment of mesenchymal stromal cells to cells supporting the nutrition and protection of neurons. |
2013-08-28 |
2023-08-12 |
monkey |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
midbrain dopaminergic neurons are implicated in various neurological and psychiatric diseases as well as drug addiction. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
here, using an embryonic stem cell in vitro differentiation system and mutant dreher mouse, we showed that lmx1a, an early regulator of midbrain dopamine neural progenitor phenotype specification, is also involved in the regulation of midbrain dopaminergic maturation by regulating gene expression of the dopamine transporter. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
furthermore, during mouse embryonic development, dopamine transporter was more severely affected by lmx1a mutation compared to other dopamine markers such as tyrosine hydroxylase and dopa decarboxylase, again supporting the role of lmx1a in midbrain dopaminergic maturation in vivo. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
thus, this study demonstrates that dopamine transporter is a direct target of lmx1a and emphasizes a novel role of lmx1a as one of regulators of mature midbrain dopaminergic neurotransmitter phenotypes. |
2013-08-14 |
2023-08-12 |
mouse |
| Cécile Moro, Napoleon Torres, Nabil El Massri, David Ratel, Daniel M Johnstone, Jonathan Stone, John Mitrofanis, Alim-Louis Benabi. Photobiomodulation preserves behaviour and midbrain dopaminergic cells from MPTP toxicity: evidence from two mouse strains. BMC neuroscience. vol 14. 2013-08-13. PMID:23531041. |
photobiomodulation preserves behaviour and midbrain dopaminergic cells from mptp toxicity: evidence from two mouse strains. |
2013-08-13 |
2023-08-12 |
mouse |
| Shane V Hegarty, Aideen M Sullivan, Gerard W O'Keeff. Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development. Developmental biology. vol 379. issue 2. 2013-08-13. PMID:23603197. |
midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development. |
2013-08-13 |
2023-08-12 |
Not clear |