| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M I Airapetov, S O Eresco, A A Lebedev, E R Bychkov, P D Shabano. [Ethanol induced increase of fibroblast growth factor 2 mRNA content in emotiogenic brain structures of rats]. Biomeditsinskaia khimiia. vol 66. issue 5. 2021-01-13. PMID:33140737. |
results suggest a possible role of fgf2 in the functioning of dopaminergic neurons in the midbrain. |
2021-01-13 |
2023-08-13 |
rat |
| Fabio Massimo Corsi, Carmela Gerace, Monica Ricc. Rotigotine effect in prolonged disturbance of consciousness. Brief report of two cases. Acta bio-medica : Atenei Parmensis. vol 91. issue 1. 2021-01-12. PMID:32191667. |
in particular, dysfunction of dopaminergic pathways from the mesencephalon to the frontal cortical areas may be responsible for clinical pictures characterized by preserved alertness and total loss of interactions with the surrounding environment; the so called "waking coma" cases. |
2021-01-12 |
2023-08-13 |
Not clear |
| Jayanth Anantha, Susan R Goulding, Sean L Wyatt, Ruth M Concannon, Louise M Collins, Aideen M Sullivan, Gerard W O'Keeff. STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5. iScience. vol 23. issue 9. 2021-01-10. PMID:32853992. |
loss of midbrain dopaminergic (mda) neurons and their axons is central to parkinson's disease (pd). |
2021-01-10 |
2023-08-13 |
rat |
| Oeystein Roed Brekk, Jonathan R Honey, Seungil Lee, Penelope J Hallett, Ole Isacso. Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 44. 2021-01-07. PMID:33060302. |
histological localization of neutral lipids using a fluorescent probe (bodipy) revealed that dopaminergic neurons and midbrain microglia significantly accumulated intracellular lipids in pd sn, while adjacent astrocytes had a reduced lipid load overall. |
2021-01-07 |
2023-08-13 |
mouse |
| Ioannis Mantas, Yunting Yang, Clotilde Mannoury-la-Cour, Mark J Millan, Xiaoqun Zhang, Per Svenningsso. Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia. Neuropharmacology. vol 162. 2021-01-06. PMID:31666199. |
parkinson's disease (pd) is characterized by progressive loss of midbrain dopaminergic neurons and treated with the dopamine precursor, 3,4-dihydroxy-l-phenylalanine (l-dopa). |
2021-01-06 |
2023-08-13 |
mouse |
| Will Collins, Nicolas Rouleau, Mattia Bonzanni, Kevin Kapner, Alex Jeremiah, Chuang Du, Emmanuel N Pothos, David L Kapla. Functional Effects of a Neuromelanin Analogue on Dopaminergic Neurons in 3D Cell Culture. ACS biomaterials science & engineering. vol 5. issue 1. 2021-01-06. PMID:33405867. |
to address this limitation, we modified our established silk 3d brain tissue model to emulate key characteristics of the snpc by using a structural analogue of nm to examine the effects of the material on dopaminergic neurons using lund's human mesencephalon (luhmes) cells. |
2021-01-06 |
2023-08-13 |
human |
| Yuko Nakamura, Naohiro Okada, Daisuke Koshiyama, Kouhei Kamiya, Osamu Abe, Akira Kunimatsu, Kazuo Okanoya, Kiyoto Kasai, Shinsuke Koik. Differences in Functional Connectivity Networks Related to the Midbrain Dopaminergic System-Related Area in Various Psychiatric Disorders. Schizophrenia bulletin. 2021-01-05. PMID:31901932. |
differences in functional connectivity networks related to the midbrain dopaminergic system-related area in various psychiatric disorders. |
2021-01-05 |
2023-08-13 |
Not clear |
| Qi-Wen Han, Yu-He Yuan, Nai-Hong Che. The therapeutic role of cannabinoid receptors and its agonists or antagonists in Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31442553. |
parkinson's disease (pd) is a neurodegenerative disease and its characteristic is the progressive degeneration of dopaminergic neurons within the substantia nigra (sn) of the midbrain. |
2021-01-04 |
2023-08-13 |
Not clear |
| Pascaline Aimé, Saravanan S Karuppagounder, Apeksha Rao, Yingxin Chen, Robert E Burke, Rajiv R Ratan, Lloyd A Green. The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease. Neurobiology of disease. vol 136. 2021-01-04. PMID:31911115. |
neuronal pc12 cells and ventral midbrain dopaminergic neurons were assessed in vitro for survival, transcription factor levels and trib3 or parkin expression after exposure to 6-hydroxydopamine or 1-methyl-4-phenylpyridinium with or without adaptaquin co-treatment. |
2021-01-04 |
2023-08-13 |
mouse |
| Sergio Espeso-Gil, Tobias Halene, Jaroslav Bendl, Bibi Kassim, Gabriella Ben Hutta, Marina Iskhakova, Neda Shokrian, Pavan Auluck, Behnam Javidfar, Prashanth Rajarajan, Sandhya Chandrasekaran, Cyril J Peter, Alanna Cote, Rebecca Birnbaum, Will Liao, Tyler Borrman, Jennifer Wiseman, Aaron Bell, Michael J Bannon, Panagiotis Roussos, John F Crary, Zhiping Weng, Stefano Marenco, Barbara Lipska, Nadejda M Tsankova, Laura Huckins, Yan Jiang, Schahram Akbaria. A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons. Genome medicine. vol 12. issue 1. 2021-01-04. PMID:32075678. |
midbrain dopaminergic neurons (mdn) represent 0.0005% of the brain's neuronal population and mediate cognition, food intake, and metabolism. |
2021-01-04 |
2023-08-13 |
Not clear |
| Georgia Minakaki, Dimitri Krainc, Lena F Burbull. The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson's Disease. Frontiers in cell and developmental biology. vol 8. 2021-01-01. PMID:33381501. |
the convergence of alpha-synuclein, mitochondrial, and lysosomal pathways in vulnerability of midbrain dopaminergic neurons in parkinson's disease. |
2021-01-01 |
2023-08-13 |
Not clear |
| Laura Bordoni, Irene Petracci, Jean Calleja-Agius, Joan G Lalor, Rosita Gabbianell. NURR1 Alterations in Perinatal Stress: A First Step towards Late-Onset Diseases? A Narrative Review. Biomedicines. vol 8. issue 12. 2020-12-29. PMID:33302583. |
nuclear receptor related 1 protein (nurr1), a transcription factor with a critical role in the development of the dopaminergic neurons in the midbrain, mediates the response to stressful environmental stimuli in the perinatal period. |
2020-12-29 |
2023-08-13 |
human |
| Surya Narayan Rath, Lingaraja Jena, Manorama Patr. Understanding ligands driven mechanism of wild and mutant aryl hydrocarbon receptor in presence of phytochemicals combating Parkinson's disease: an Journal of biomolecular structure & dynamics. vol 38. issue 3. 2020-12-28. PMID:30836878. |
b[a] p induces oxidative stress and causes degeneration of dopaminergic neurons in the midbrain, may leads to parkinson's disease (pd). |
2020-12-28 |
2023-08-13 |
Not clear |
| Justin K Siemann, Piper Williams, Turnee N Malik, Chad R Jackson, Noah H Green, Ronald B Emeson, Pat Levitt, Douglas G McMaho. Photoperiodic effects on monoamine signaling and gene expression throughout development in the serotonin and dopamine systems. Scientific reports. vol 10. issue 1. 2020-12-15. PMID:32963273. |
hence, we evaluated, at multiple stages of postnatal development, the expression of key dopaminergic (th) and serotonergic (tph2, sert, and pet-1) genes, and midbrain monoamine content in mice raised under control equinox (ld 12:12), short winter-like (ld 8:16), or long summer-like (ld 16:8) photoperiods. |
2020-12-15 |
2023-08-13 |
mouse |
| Michael Freedberg, Andrew C Toader, Eric M Wassermann, Joel L Vos. Competitive and cooperative interactions between medial temporal and striatal learning systems. Neuropsychologia. vol 136. 2020-12-11. PMID:31733236. |
the involvement of other regions, such as midbrain dopaminergic nuclei and the prefrontal cortex, may promote and mediate cooperation between the striatum and the mtl during learning. |
2020-12-11 |
2023-08-13 |
Not clear |
| Tingting Di, Ya Wang, Yajie Zhang, Sha Sha, Yanying Zeng, Ling Che. Dopaminergic afferents from midbrain to dorsolateral bed nucleus of stria terminalis inhibit release and expression of corticotropin-releasing hormone in paraventricular nucleus. Journal of neurochemistry. vol 154. issue 2. 2020-12-10. PMID:32096869. |
dopaminergic afferents from midbrain to dorsolateral bed nucleus of stria terminalis inhibit release and expression of corticotropin-releasing hormone in paraventricular nucleus. |
2020-12-10 |
2023-08-13 |
mouse |
| Tingting Di, Ya Wang, Yajie Zhang, Sha Sha, Yanying Zeng, Ling Che. Dopaminergic afferents from midbrain to dorsolateral bed nucleus of stria terminalis inhibit release and expression of corticotropin-releasing hormone in paraventricular nucleus. Journal of neurochemistry. vol 154. issue 2. 2020-12-10. PMID:32096869. |
dopaminergic (daergic) neurons of the midbrain ventral tegmental area (vta) are known to regulate the hypothalamic-pituitary-adrenal (hpa) axis but have no direct projections to the paraventricular nucleus (pvn) of the hypothalamus. |
2020-12-10 |
2023-08-13 |
mouse |
| Jan Grohn, Urs Schüffelgen, Franz-Xaver Neubert, Alessandro Bongioanni, Lennart Verhagen, Jerome Sallet, Nils Kolling, Matthew F S Rushwort. Multiple systems in macaques for tracking prediction errors and other types of surprise. PLoS biology. vol 18. issue 10. 2020-12-09. PMID:33125367. |
activity in the vicinity of the dopaminergic midbrain only reflected surprise about the amount of reward. |
2020-12-09 |
2023-08-13 |
Not clear |
| N V Katolikova, A B Malashicheva, R R Gainetdino. [Cell Replacement Therapy in Parkinson's Disease-History of Development and Prospects for Use in Clinical Practice]. Molekuliarnaia biologiia. vol 54. issue 6. 2020-12-09. PMID:33276357. |
parkinson's disease is a widespread neurodegenerative disease, which is characterized by the death of dopaminergic neurons in the substantia nigra of the midbrain. |
2020-12-09 |
2023-08-13 |
Not clear |
| Raniki Kumari, Roshan Kumar, Sanjay Kumar, Abhishek Kumar Singh, Pranita Hanpude, Deepak Jangir, Tushar Kanti Mait. Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease. The Journal of biological chemistry. vol 295. issue 11. 2020-12-07. PMID:32005664. |
parkinson's disease (pd) is a multifactorial malady and the second most common neurodegenerative disorder, characterized by loss of dopaminergic neurons in the midbrain. |
2020-12-07 |
2023-08-13 |
mouse |