| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Canan Beate Schüller, Ben Jonathan Wagner, Thomas Schüller, Juan Carlos Baldermann, Daniel Huys, Julia Kerner Auch Koerner, Eva Niessen, Alexander Münchau, Valerie Brandt, Jan Peters, Jens Kuh. Temporal discounting in adolescents and adults with Tourette syndrome. PloS one. vol 16. issue 6. 2021-11-16. PMID:34143854. |
dopaminergic hyperactivity in the basal ganglia has previously been linked to increased sensitivity to positive reinforcement and increases in choice impulsivity. |
2021-11-16 |
2023-08-13 |
human |
| Eleanor Porter, Andreas-Antonios Roussakis, Nicholas P Lao-Kaim, Paola Piccin. Multimodal dopamine transporter (DAT) imaging and magnetic resonance imaging (MRI) to characterise early Parkinson's disease. Parkinsonism & related disorders. vol 79. 2021-11-15. PMID:32861103. |
currently, in early idiopathic pd, dopamine transporter (dat)-specific imaging assesses the extent of striatal dopaminergic deficits, and conventional magnetic resonance imaging (mri) of the brain excludes the presence of significant ischaemic load in the basal ganglia as well as signs indicative of other forms of parkinsonism. |
2021-11-15 |
2023-08-13 |
Not clear |
| B J Wilkes, J C DeSimone, Y Liu, W T Chu, S A Coombes, Y Li, D E Vaillancour. Cell-specific effects of Dyt1 knock-out on sensory processing, network-level connectivity, and motor deficits. Experimental neurology. vol 343. 2021-11-09. PMID:34119482. |
these findings suggest that (1) the added impact of torsina dysfunction in medium spiny and dopaminergic neurons of the basal ganglia generate more profound deficits than the dysfunction of cholinergic neurons alone, and (2) that sensory network impairments are linked to motor deficits in dyt1 dystonia. |
2021-11-09 |
2023-08-13 |
mouse |
| V M DeAngelo, J D Hilliard, G C McConnel. Dopaminergic but not cholinergic neurodegeneration is correlated with gait disturbances in PINK1 knockout rats. Behavioural brain research. vol 417. 2021-11-08. PMID:34534596. |
pd hallmarks include a decrease in stride length, run speed, and swing time; an increase in stride time, stance time, and base of support; dopaminergic degeneration in the basal ganglia; and cholinergic degeneration in the pedunculopontine nucleus (ppn). |
2021-11-08 |
2023-08-13 |
rat |
| b' Antonio Gennaro Nicotera, Gabriella Di Rosa, Laura Turriziani, Maria Cristina Costanzo, Emanuela Stracuzzi, Girolamo Aurelio Vitello, Rosanna Galati Rando, Antonino Musumeci, Mirella Vinci, Sebastiano Antonino Musumeci, Francesco Cal\\xc3\\xa. Role of COMT V158M Polymorphism in the Development of Dystonia after Administration of Antipsychotic Drugs. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679357.' |
typically, dystonic movements are considered the result of impaired function and/or abnormalities of dopaminergic neurotransmission/signaling in the basal ganglia. |
2021-10-26 |
2023-08-13 |
Not clear |
| Alicia M P Warnecke, Moon S Kang, Michael W Jakowec, Daryl L Davie. The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease. Behavioural brain research. vol 393. 2021-10-25. PMID:32668263. |
p2 × 4rs are expressed throughout the central nervous system including the dopaminergic circuitry of the substantia nigra, basal ganglia, and related reward networks. |
2021-10-25 |
2023-08-13 |
mouse |
| Kathryn Biernacki, Mei-Heng Lin, Travis E Bake. Recovery of reward function in problematic substance users using a combination of robotics, electrophysiology, and TMS. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 158. 2021-10-25. PMID:33068631. |
theoretical and empirical work suggest that addictive drugs potentiate dopaminergic reinforcement learning signals and disrupt the reward function of its neural targets, including the anterior midcingulate cortex (amcc) and the basal ganglia. |
2021-10-25 |
2023-08-13 |
Not clear |
| Reka Natarajan, Bryan K Yamamot. The Basal Ganglia as a Substrate for the Multiple Actions of Amphetamines. Basal ganglia. vol 1. issue 2. 2021-10-20. PMID:21804952. |
this review focuses on how alterations in dopaminergic neurotransmission within distinct basal ganglia pathways can modify their functional output to predict and explain the acute and long term behavioral consequences of amphetamine exposure. |
2021-10-20 |
2023-08-12 |
Not clear |
| Lars Freudenmacher, Maria Schauer, Wolfgang Walkowiak, Arndt von Twicke. Refinement of the dopaminergic system of anuran amphibians based on connectivity with habenula, basal ganglia, limbic system, pallium, and spinal cord. The Journal of comparative neurology. vol 528. issue 6. 2021-10-18. PMID:31617943. |
refinement of the dopaminergic system of anuran amphibians based on connectivity with habenula, basal ganglia, limbic system, pallium, and spinal cord. |
2021-10-18 |
2023-08-13 |
Not clear |
| Kim De Keyser, Miet De Letter, Patrick Santens, Durk Talsma, Dick Botteldooren, Annelies Bockstae. Neurophysiological investigation of auditory intensity dependence in patients with Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 3. 2021-10-15. PMID:33515333. |
this interpretation is consistent with the involvement of the basal ganglia and the role of dopaminergic and serotonergic neurotransmission in auditory gating. |
2021-10-15 |
2023-08-13 |
human |
| Merve Kasap, Donard S Dwye. Na Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 6. 2021-10-15. PMID:33961117. |
na parkinson's disease (pd) is a debilitating movement disorder often accompanied by neuropsychiatric symptoms that stem from the loss of dopaminergic function in the basal ganglia and altered neurotransmission more generally. |
2021-10-15 |
2023-08-13 |
Not clear |
| Alexander N Rodichkin, Melissa K Edler, Jennifer L McGlothan, Tomás R Guilart. Behavioral and neurochemical studies of inherited manganese-induced dystonia-parkinsonism in Slc39a14-knockout mice. Neurobiology of disease. vol 158. 2021-10-14. PMID:34358615. |
the pathophysiology of this disease is unknown, but the nigrostriatal dopaminergic system of the basal ganglia has been implicated. |
2021-10-14 |
2023-08-13 |
mouse |
| Shivam Kumar, Lav Goyal, Shamsher Sing. Tremor and Rigidity in Patients with Parkinson's Disease: Emphasis on Epidemiology, Pathophysiology and Contributing Factors. CNS & neurological disorders drug targets. 2021-10-08. PMID:34620070. |
this is mainly triggered by the depletion of dopaminergic neurons located in substantia nigra pars compacta (snpc) in the region of basal ganglia. |
2021-10-08 |
2023-08-13 |
Not clear |
| Robert A McCutcheon, Kate Merritt, Oliver D Howe. Dopamine and glutamate in individuals at high risk for psychosis: a meta-analysis of in vivo imaging findings and their variability compared to controls. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 20. issue 3. 2021-09-23. PMID:34505389. |
there were no significant differences between high-risk individuals and controls in striatal presynaptic dopaminergic function, striatal d2/d3 receptor availability, prefrontal cortex glutamate or glx, hippocampal glutamate or glx, or basal ganglia glx. |
2021-09-23 |
2023-08-13 |
Not clear |
| Peter A Kempster, Laura Perju-Dumbrav. The Thermodynamic Consequences of Parkinson's Disease. Frontiers in neurology. vol 12. 2021-09-14. PMID:34512508. |
that the dopaminergic deficit of pd creates a problem with energy efficiency highlights the role played by the basal ganglia, and by dopamine, in thermodynamic governance. |
2021-09-14 |
2023-08-13 |
Not clear |
| Owen M Peters, Alexandra Weiss, Jake Metterville, Lina Song, Robert Logan, Gaynor A Smith, Michael A Schwarzschild, Christian Mueller, Robert H Brown, Marc Freema. Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease. Neurobiology of disease. vol 155. 2021-09-03. PMID:33892050. |
parkinson's disease (pd) is the most common form of neurodegenerative movement disorder, associated with profound loss of dopaminergic neurons from the basal ganglia. |
2021-09-03 |
2023-08-13 |
mouse |
| Jie Zhao, Manish Kumar, Jeevan Sharma, Zhihai Yua. Arbutin effectively ameliorates the symptoms of Parkinson's disease: the role of adenosine receptors and cyclic adenosine monophosphate. Neural regeneration research. vol 16. issue 10. 2021-08-21. PMID:33642391. |
an antagonistic communication exists between adenosinergic and dopaminergic signaling in the basal ganglia, which suggests that the suppression of adenosine a |
2021-08-21 |
2023-08-13 |
Not clear |
| Florence Véronneau-Veilleux, Mauro Ursino, Philippe Robaey, Daniel Lévesque, Fahima Nekk. Nonlinear pharmacodynamics of levodopa through Parkinson's disease progression. Chaos (Woodbury, N.Y.). vol 30. issue 9. 2021-08-18. PMID:33003902. |
this can be attributed to different compensation mechanisms taking place in the basal ganglia where the dopaminergic neurons are progressively lost. |
2021-08-18 |
2023-08-13 |
Not clear |
| Huma Ikram, Shoaib Ahmed, Darakhshan Jabeen Halee. Restraint-induced behavioral deficits are attenuated or impaired by pre- or post-injection of apomorphine: A context-based study. Pakistan journal of pharmaceutical sciences. vol 33. issue 3. 2021-08-03. PMID:33191219. |
this dopaminergic dysfunction is more pre-dominant in basal ganglia and prefrontal cortex. |
2021-08-03 |
2023-08-13 |
rat |
| Anna Maria Szota, Jørgen Scheel-Krüge. The role of glutamate receptors and their interactions with dopamine and other neurotransmitters in the development of tardive dyskinesia: preclinical and clinical results. Behavioural pharmacology. vol 31. issue 6. 2021-08-02. PMID:32459694. |
the leading preclinical hypothesis of tardive dyskinesia development includes dopaminergic imbalance in the direct and indirect pathways of the basal ganglia, cholinergic deficiency, serotonin receptor disturbances, neurotoxicity, oxidative stress, and changes in synaptic plasticity. |
2021-08-02 |
2023-08-13 |
Not clear |