| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rupert D Smit, Biswarup Ghosh, Thomas J Campion, Rachel Stingel, Emily Lavell, Robert Hooper, Xiaoxuan Fan, Jonathan Soboloff, George M Smit. STAT3 protects dopaminergic neurons against degeneration in animal model of Parkinson's disease. Brain research. vol 1824. 2023-12-01. PMID:38030102. |
parkinson's disease (pd) is the most prevalent disorder of the basal ganglia, propagated by the degeneration of axon terminals within the striatum and subsequent loss of dopaminergic neurons in the substantia nigra (sn). |
2023-12-01 |
2023-12-10 |
Not clear |
| Rafael Rivas-Santisteban, Alberto Rico, Ana Muñoz, Ana I Rodriguez, Irene Reyes-Resina, Gemma Navarro, José Luis Labandeira-García, José Luis Lanciego, Rafael Franc. Boolean analysis shows a high proportion of dopamine D Neurobiology of disease. 2023-11-02. PMID:37918757. |
boolean analysis shows a high proportion of dopamine d the antagonistic effect of adenosine on dopaminergic transmission in the basal ganglia indirect motor control pathway is mediated by dopamine d |
2023-11-02 |
2023-11-08 |
Not clear |
| Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in parkinson's disease. |
2023-10-22 |
2023-11-08 |
mouse |
| Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
the degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia is responsible for the cardinal motor symptoms of parkinson's disease (pd). |
2023-10-22 |
2023-11-08 |
mouse |
| Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
it has been thought that loss of dopaminergic signaling in one basal ganglia region - the striatum - was solely responsible for the network pathophysiology causing pd motor symptoms. |
2023-10-22 |
2023-11-08 |
mouse |
| Donato Colella, Massimiliano Passaretti, Viviana Frantellizzi, Maria Silvia De Feo, Antonio Cannavacciuolo, Luca Angelini, Daniele Birreci, Davide Costa, Giulia Paparella, Andrea Guerra, Giuseppe De Vincentis, Alfredo Berardelli, Matteo Bologn. Subtle changes in central dopaminergic tone underlie bradykinesia in essential tremor. NeuroImage. Clinical. vol 40. 2023-10-17. PMID:37847966. |
in this research, our primary objective was to explore the correlation between basal ganglia dopaminergic neurotransmission, assessed using 123i-fp-cit (dat-spect), and finger movements abnormalities in patients with essential tremor (et) and parkinson's disease (pd). |
2023-10-17 |
2023-11-08 |
Not clear |
| Ridhima Vij, Alan Prossin, Mallika Tripathy, Hosu Kim, Hyeonggeun Park, Thanh Cheng, Djamchid Lotfi, Donna Chan. Long-term, repeated doses of intravenous autologous mesenchymal stem cells for a patient with Parkinson's disease: a case report. Frontiers in neurology. vol 14. 2023-10-16. PMID:37840944. |
parkinson's disease (pd) is a neurodegenerative disease that involves the loss of dopaminergic neurons in the substantia nigra pars compacta of the basal ganglia. |
2023-10-16 |
2023-11-08 |
Not clear |
| İrem Akçalı, Simla Su Akkan, Mehmet Bülbü. The Regulatory Role of Central Neuropeptide-S in Locomotion. Peptides. 2023-10-13. PMID:37832875. |
nps receptor (npsr) is produced in locomotion-related brain regions including basal ganglia while nps mediates dopaminergic neurotransmission suggesting that endogenous brain nps is involved in the regulation of locomotion. |
2023-10-13 |
2023-10-15 |
rat |
| Daisuke Hatta, Kaito Kanamoto, Shiho Makiya, Kaori Watanabe, Tatsuya Kishino, Akira Kinoshita, Koh-Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwat. Proline-rich transmembrane protein 2 knock-in mice present dopamine-dependent motor deficits. Journal of biochemistry. 2023-10-04. PMID:37793168. |
although previous studies have shown that pkd might be caused by cerebellar dysfunction, prrt2 has not been sufficiently analyzed in some motor-related regions including the basal ganglia, where dopaminergic neurons are most abundant in the brain. |
2023-10-04 |
2023-10-07 |
mouse |
| Martin E Johansson, Ivan Toni, Roy P C Kessels, Bastiaan R Bloem, Rick C Helmic. Clinical severity in Parkinson's disease is determined by decline in cortical compensation. Brain : a journal of neurology. 2023-09-27. PMID:37757883. |
dopaminergic dysfunction in the basal ganglia, particularly in the posterior putamen, is often viewed as the primary pathological mechanism behind motor slowing (i.e., bradykinesia) in parkinson's disease. |
2023-09-27 |
2023-10-07 |
Not clear |
| Victor Pando-Naude, Tomas Edward Matthews, Andreas Højlund, Sebastian Jakobsen, Karen Østergaard, Erik Johnsen, Eduardo A Garza-Villarreal, Maria A G Witek, Virginia Penhune, Peter Vuus. Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms. The European journal of neuroscience. 2023-09-19. PMID:37724707. |
dopamine in motor and limbic networks is implicated in beat-based timing and music-induced pleasure, suggesting a central role of basal ganglia (bg) dopaminergic systems in plumm. |
2023-09-19 |
2023-10-07 |
human |
| Fernando Falkenburger Melleu, Newton Sabino Cantera. Pathways from the Superior Colliculus to the Basal Ganglia. Current neuropharmacology. 2023-09-13. PMID:37702174. |
moreover, we discuss how information from the sc might also be relayed to the basal ganglia through midbrain tectonigral and tectotegmental projections directed at the substantia nigra compacta and ventrotegmental area, respectively, influencing the dopaminergic outflow to the dorsal and ventral striatum. |
2023-09-13 |
2023-10-07 |
Not clear |
| Véronique Coizet, Racha Al Tannir, Arnaud Pautrat, Paul G Overto. Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures. Current neuropharmacology. 2023-08-18. PMID:37594168. |
in this review, we describe how brainstem structures also project to the main input structures of the basal ganglia, namely the striatum, the subthalamic nucleus and midbrain dopaminergic neurons, in the context of approach and avoidance (including escape from threat), two fundamental, mutually exclusive behavioral choices in an animal's repertoire in which the brainstem is strongly involved. |
2023-08-18 |
2023-09-07 |
Not clear |
| Véronique Coizet, Racha Al Tannir, Arnaud Pautrat, Paul G Overto. Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures. Current neuropharmacology. 2023-08-18. PMID:37594168. |
we consider what is known about how these structures are related to the basal ganglia, focusing on their projections toward the striatum, dopaminergic neurons and subthalamic nucleus, and explore the functional consequences of those interactions. |
2023-08-18 |
2023-09-07 |
Not clear |
| Chayaporn Reakkamnuan, Ekkasit Kumarnsit, Dania Cheah. Local field potential (LFP) power and phase-amplitude coupling (PAC) changes in the striatum and motor cortex reflect neural mechanisms associated with bradykinesia and rigidity during D2R suppression in an animal model. Progress in neuro-psychopharmacology & biological psychiatry. 2023-08-09. PMID:37557945. |
impairments in motor control are the primary feature of parkinson's disease, which is caused by dopaminergic imbalance in the basal ganglia. |
2023-08-09 |
2023-08-16 |
mouse |
| Emil Wärnberg, Arvind Kuma. Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 32. 2023-08-01. PMID:37527344. |
it is well established that midbrain dopaminergic neurons support reinforcement learning (rl) in the basal ganglia by transmitting a reward prediction error (rpe) to the striatum. |
2023-08-01 |
2023-08-14 |
Not clear |
| Pooja Mittal, Sanchit Dhankhar, Samrat Chauhan, Nitika Garg, Tanima Bhattacharya, Maksood Ali, Anis Ahmad Chaudhary, Hassan Ahmad Rudayni, Mohammed Al-Zharani, Wasim Ahmad, Salah Ud-Din Khan, Thakur Gurjeet Singh, Somdutt Mujwa. A Review on Natural Antioxidants for Their Role in the Treatment of Parkinson's Disease. Pharmaceuticals (Basel, Switzerland). vol 16. issue 7. 2023-07-29. PMID:37513820. |
the neurodegenerative condition known as parkinson's disease (pd) is brought on by the depletion of dopaminergic neurons in the basal ganglia, which is the brain region that controls body movement. |
2023-07-29 |
2023-08-14 |
Not clear |
| Alejandro G Rey Hipolito, Meike E van der Heijden, Roy V Sillito. Physiology of Dystonia: Animal Studies. International review of neurobiology. vol 169. 2023-07-23. PMID:37482392. |
in the basal ganglia, changes in dopaminergic, serotonergic, noradrenergic, and cholinergic signaling are found across different animal models. |
2023-07-23 |
2023-08-14 |
Not clear |
| Marcello Serra, Anna Di Maio, Valentina Bassareo, Tommaso Nuzzo, Francesco Errico, Federica Servillo, Mario Capasso, Pathik Parekh, Qin Li, Marie-Laure Thiolat, Erwan Bezard, Paolo Calabresi, David Sulzer, Manolo Carta, Micaela Morelli, Alessandro Usiell. Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. Neurobiology of disease. 2023-07-14. PMID:37451474. |
here, through high-performance liquid chromatography (hplc), we measured the levels of these amino acids in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated monkeys and mptp-plus-probenecid (mptpp)-treated mice to determine whether and how dopaminergic midbrain degeneration affects the levels of serine enantiomers in various basal ganglia subregions. |
2023-07-14 |
2023-08-14 |
mouse |
| Erin M Radcliffe, Alexander J Baumgartner, Drew S Kern, Mazen Al Borno, Steven Ojemann, Daniel R Kramer, John A Thompso. Oscillatory beta dynamics inform biomarker-driven treatment optimization for Parkinson's disease. Journal of neurophysiology. 2023-05-17. PMID:37198135. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by loss of dopaminergic neurons and dysregulation of the basal ganglia. |
2023-05-17 |
2023-08-14 |
Not clear |