| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yadan Zhao, Zichen Zhang, Siru Qin, Wen Fan, Wei Li, Jingyi Liu, Songtao Wang, Zhifang Xu, Meidan Zha. Acupuncture for Parkinson's Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit. Neural plasticity. vol 2021. 2021-07-29. PMID:34221005. |
it has also been found that acupuncture can protect dopaminergic neurons from degeneration via antioxidative stress, anti-inflammatory, and antiapoptotic pathways as well as modulating the neurotransmitter balance in the basal ganglia circuit. |
2021-07-29 |
2023-08-13 |
Not clear |
| Talita Glaser, Roberta Andrejew, Ágatha Oliveira-Giacomelli, Deidiane Elisa Ribeiro, Lucas Bonfim Marques, Qing Ye, Wen-Jing Ren, Alexey Semyanov, Peter Illes, Yong Tang, Henning Ulric. Purinergic Receptors in Basal Ganglia Diseases: Shared Molecular Mechanisms between Huntington's and Parkinson's Disease. Neuroscience bulletin. vol 36. issue 11. 2021-07-28. PMID:33026587. |
huntington's (hd) and parkinson's diseases (pd) are neurodegenerative disorders caused by the death of gabaergic and dopaminergic neurons in the basal ganglia leading to hyperkinetic and hypokinetic symptoms, respectively. |
2021-07-28 |
2023-08-13 |
Not clear |
| Yiqiu Liu, Junyu Deng, Ye Liu, Wei Li, Xuqiang Ni. FGF, Mechanism of Action, Role in Parkinson's Disease, and Therapeutics. Frontiers in pharmacology. vol 12. 2021-07-09. PMID:34234672. |
the death or dysfunction of dopaminergic neurons in the dense part of the substantia nigra leads to dopamine deficiency in the basal ganglia and motor dysfunction. |
2021-07-09 |
2023-08-13 |
Not clear |
| Simon Moskowitz, David W Russ, Leatha A Clark, Nathan P Wages, Dustin R Grooms, Adam J Woods, Julie Suhr, Janet E Simon, Andrew O'Shea, Cody R Criss, Paolo Fadda, Brian C Clar. Is impaired dopaminergic function associated with mobility capacity in older adults? GeroScience. vol 43. issue 3. 2021-07-01. PMID:33236263. |
in this article, we report four pieces of complementary evidence from behavioral, genetic, and neuroimaging experiments that, we believe, provide theoretical support for the assertion that the basal ganglia and its dopaminergic function are responsible, in part, for age-related reductions in mobility. |
2021-07-01 |
2023-08-13 |
Not clear |
| Simon Moskowitz, David W Russ, Leatha A Clark, Nathan P Wages, Dustin R Grooms, Adam J Woods, Julie Suhr, Janet E Simon, Andrew O'Shea, Cody R Criss, Paolo Fadda, Brian C Clar. Is impaired dopaminergic function associated with mobility capacity in older adults? GeroScience. vol 43. issue 3. 2021-07-01. PMID:33236263. |
these findings align with recent basic and clinical science work suggesting that the basal ganglia and its dopaminergic function are mechanistically linked to age-related reductions in mobility capacity. |
2021-07-01 |
2023-08-13 |
Not clear |
| Christopher R Kelley, Jeffrey L Kauffma. Optimal Control Perspective on Parkinson's Disease: Increased Delay Between State Estimator and Controller Produces Tremor. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 28. issue 10. 2021-06-24. PMID:32822299. |
contextualization of the optimal control model with physiological models and clinical observations provides insight into the potential role of the basal ganglia and cerebello-thalamo-cortical circuit and how treatments like dopaminergic medications and deep brain stimulation reduce tremor. |
2021-06-24 |
2023-08-13 |
human |
| Beatrice Orso, Dario Arnaldi, Francesco Famà, Nicola Girtler, Andrea Brugnolo, Elisa Doglione, Laura Filippi, Federico Massa, Enrico Peira, Matteo Bauckneht, Silvia Morbelli, Flavio Nobili, Matteo Pardin. Anatomical and neurochemical bases of theory of mind in de novo Parkinson's Disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 130. 2021-06-21. PMID:32755727. |
we acquired fdg-pet images (as a marker of regional neurodegeneration), i-123 ioflupane single photon emission computed tomography (123 i-fp-cit-spect, as a marker of dopaminergic impairment in the basal ganglia and in the cortex and as a proxy marker of serotoninergic deafferentation in the thalamus), and qeeg recordings (using the theta/alpha power ratio as marker of cholinergic deafferentation). |
2021-06-21 |
2023-08-13 |
human |
| E Hill, R Gowers, M J E Richardson, M J Wal. α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide. eNeuro. vol 8. issue 1. 2021-06-18. PMID:33229413. |
dopaminergic neurons (dns) in the substantia nigra pars compacta (snpc) form an important part of the basal ganglia circuitry, playing key roles in movement initiation and coordination. |
2021-06-18 |
2023-08-13 |
Not clear |
| Kristen N Hirter, Elaine N Miller, Cheryl D Stimpson, Kimberley A Phillips, William D Hopkins, Patrick R Hof, Chet C Sherwood, C Owen Lovejoy, Mary Ann Raghant. The nucleus accumbens and ventral pallidum exhibit greater dopaminergic innervation in humans compared to other primates. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34032910. |
our data show that humans have a significantly greater dopaminergic innervation in both structures, supporting the hypothesis that selection for a prosocial neurochemistry in the human basal ganglia may have contributed to the evolution of our uniquely social behavior profile. |
2021-06-15 |
2023-08-13 |
human |
| Roberto Limongi, Michael Mackinley, Kara Dempster, Ali R Khan, Joseph S Gati, Lena Palaniyappa. Frontal-striatal connectivity and positive symptoms of schizophrenia: implications for the mechanistic basis of prefrontal rTMS. European archives of psychiatry and clinical neuroscience. vol 271. issue 1. 2021-06-06. PMID:32683527. |
it has been hypothesized that high-frequency rtms of the ldlpfc might increase the dopaminergic neurotransmission by driving the activity of the left striatum in the basal ganglia (lstr)-increasing striatal dopaminergic activity. |
2021-06-06 |
2023-08-13 |
human |
| Collin M Bantle, C Tenley French, Jason E Cummings, Shankar Sadasivan, Kevin Tran, Richard A Slayden, Richard J Smeyne, Ronald B Tjalken. Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus. PloS one. vol 16. issue 1. 2021-05-10. PMID:33493177. |
analyses of dopaminergic neurons, microglia and astrocytes in basal ganglia indicated that although there was no significant loss of dopaminergic neurons within the substantia nigra pars compacta, there was more pronounced activation of microglia and astrocytes in animals sequentially exposed to mn and h1n1, as well as altered patterns of histone acetylation. |
2021-05-10 |
2023-08-13 |
mouse |
| Rebekah C Evans, Emily L Twedell, Manhua Zhu, Jefferson Ascencio, Renshu Zhang, Zayd M Khali. Functional Dissection of Basal Ganglia Inhibitory Inputs onto Substantia Nigra Dopaminergic Neurons. Cell reports. vol 32. issue 11. 2021-05-04. PMID:32937133. |
functional dissection of basal ganglia inhibitory inputs onto substantia nigra dopaminergic neurons. |
2021-05-04 |
2023-08-13 |
Not clear |
| Zahra Jafari, Bryan E Kolb, Majid H Mohajeran. Auditory Dysfunction in Parkinson's Disease. Movement disorders : official journal of the Movement Disorder Society. vol 35. issue 4. 2021-04-27. PMID:32052894. |
improvement in auditory responses following dopaminergic therapies also indicates the presence of similar neurotransmitters (i.e., glutamate and dopamine) in the auditory system and basal ganglia. |
2021-04-27 |
2023-08-13 |
Not clear |
| Federica Campanelli, Daniela Laricchiuta, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Barbara Picconi, Laura Petrosini, Paolo Calabresi, Veronica Ghiglier. Long-Term Shaping of Corticostriatal Synaptic Activity by Acute Fasting. International journal of molecular sciences. vol 22. issue 4. 2021-04-23. PMID:33671915. |
this basal ganglia nucleus is involved in habit formation and in eating behavior, especially that based on dopaminergic control of motivation for food in both humans and animals. |
2021-04-23 |
2023-08-13 |
mouse |
| Pragathi Priyadharsini Balasubramani, V Srinivasa Chakravarth. Bipolar oscillations between positive and negative mood states in a computational model of Basal Ganglia. Cognitive neurodynamics. vol 14. issue 2. 2021-04-02. PMID:32226561. |
phenomenological and network models of the basal ganglia extend that logic, and interpret bipolar oscillations in terms of the activity of dopaminergic and serotonergic projections on the cortico-basal ganglia network dynamics. |
2021-04-02 |
2023-08-13 |
Not clear |
| Mario Antonazzo, Sonia María Gomez-Urquijo, Luisa Ugedo, Teresa Morera-Herrera. Dopaminergic denervation impairs cortical motor and associative/limbic information processing through the basal ganglia and its modulation by the CB1 receptor. Neurobiology of disease. vol 148. 2021-03-23. PMID:33278598. |
dopaminergic denervation impairs cortical motor and associative/limbic information processing through the basal ganglia and its modulation by the cb1 receptor. |
2021-03-23 |
2023-08-13 |
rat |
| Giorgia Ponsi, Marina Scattolin, Riccardo Villa, Salvatore Maria Agliot. Human moral decision-making through the lens of Parkinson's disease. NPJ Parkinson's disease. vol 7. issue 1. 2021-03-20. PMID:33654110. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the basal ganglia (bg) and thalamocortical circuitry. |
2021-03-20 |
2023-08-13 |
human |
| Mohan K Ghanta, P Elango, Bhaskar L V K . Current Therapeutic Strategies and Perspectives for Neuroprotection in Parkinson's Disease. Current pharmaceutical design. vol 26. issue 37. 2021-03-19. PMID:32065086. |
parkinson's disease is a progressive neurodegenerative disorder of dopaminergic striatal neurons in basal ganglia. |
2021-03-19 |
2023-08-13 |
Not clear |
| R Mark Richardson, Krystof S Bankiewicz, Chadwick W Christine, Amber D Van Laar, Robert E Gross, Russell Lonser, Stewart A Factor, Sandra K Kostyk, Adrian P Kells, Bernard Ravina, Paul S Larso. Data-driven evolution of neurosurgical gene therapy delivery in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 91. issue 11. 2021-03-19. PMID:32732384. |
loss of nigrostriatal dopaminergic projection neurons is a key pathology in parkinson's disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor features. |
2021-03-19 |
2023-08-13 |
human |
| Marco Pozzi, Silvana Bertella, Erika Gatti, Gabriëlla G A M Peeters, Carla Carnovale, Stefania Zambrano, Maria Nobil. Emerging drugs for the treatment of attention-deficit hyperactivity disorder (ADHD). Expert opinion on emerging drugs. vol 25. issue 4. 2021-03-16. PMID:32938246. |
current pharmacological treatments for adhd are based on stimulant or non-stimulant medications, targeting dopaminergic and noradrenergic systems in the frontal cortex and dopaminergic system in the basal ganglia. |
2021-03-16 |
2023-08-13 |
Not clear |