| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
these findings suggest that the dopaminergic neurotransmitter system of the basal ganglia in patients with ocd could be involved in the pathophysiology of ocd. |
2004-10-05 |
2023-08-12 |
Not clear |
| Genela Morris, David Arkadir, Alon Nevet, Eilon Vaadia, Hagai Bergma. Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons. Neuron. vol 43. issue 1. 2004-08-26. PMID:15233923. |
we conclude that the striatal cholinergic and dopaminergic systems carry distinct messages by different means, which can be integrated differently to shape the basal ganglia responses to reward-related events. |
2004-08-26 |
2023-08-12 |
monkey |
| Genela Morris, Alon Nevet, Hagai Bergma. Anatomical funneling, sparse connectivity and redundancy reduction in the neural networks of the basal ganglia. Journal of physiology, Paris. vol 97. issue 4-6. 2004-08-24. PMID:15242667. |
we recorded the simultaneous activity of neurons in the output stages of the basal ganglia as well as the activity of dopaminergic and cholinergic neurons during the performance of a probability decision-making task. |
2004-08-24 |
2023-08-12 |
Not clear |
| Masaya Segaw. [Visual child neurology]. Rinsho shinkeigaku = Clinical neurology. vol 43. issue 11. 2004-08-13. PMID:15152453. |
here, i reviewed the characteristic symptoms and their pathophysiologies of rett syndrome, dyt-1, autosomal dominant gtp cyclohydrolase i (adgch i) deficiency, tourette syndrome (ts) and early-onset ataxia with ocular motor apraxia and hypoalbuminemia (eaoh), and suggested that the brainstem aminergic neurons modulating the locomotion have roles for development of the frontal cortex, the dopaminergic neurons and basal ganglia pathways involving in the action dystonia for motor execution and the serotonergic and the dopaminergic neurons projectioning to the nonmotor basal ganglia thalamocortical circuits for development of the frontal area, the targets of the circuits. |
2004-08-13 |
2023-08-12 |
Not clear |
| Peter Brown, Paolo Mazzone, Antonio Oliviero, Maria Grazia Altibrandi, Fabio Pilato, Pietro A Tonali, Vincenzo Di Lazzar. Effects of stimulation of the subthalamic area on oscillatory pallidal activity in Parkinson's disease. Experimental neurology. vol 188. issue 2. 2004-08-10. PMID:15246847. |
the results point to a possible common mechanism by which both dopaminergic treatment associated synchronisation of subthalamic activity at very high frequency and synchronisation imposed by therapeutic stimulation of the subthalamic area inhibit an abnormal and potentially deleterious synchronisation of basal ganglia output at around 20 hz. |
2004-08-10 |
2023-08-12 |
human |
| Damiaan Denys, Nic van der Wee, Joost Janssen, Femke De Geus, Herman G M Westenber. Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder. Biological psychiatry. vol 55. issue 10. 2004-06-14. PMID:15121489. |
despite growing evidence for involvement of the dopaminergic system in obsessive-compulsive disorder (ocd), the functional anatomy of the dopaminergic system in the basal ganglia has been investigated sparsely. |
2004-06-14 |
2023-08-12 |
Not clear |
| F Delis, A Mitsacos, P Giompre. Dopamine receptor and transporter levels are altered in the brain of Purkinje Cell Degeneration mutant mice. Neuroscience. vol 125. issue 1. 2004-06-03. PMID:15051164. |
the results suggest an increased excitatory input on the dopaminergic mesencephalic neurons and an alteration of the dopaminergic neurotransmission in basal ganglia, cortical and limbic regions of the nna1pcd mutant mouse. |
2004-06-03 |
2023-08-12 |
mouse |
| L Blanco-Lezcano, L L Rocha-Arrieta, L Martínez-Martí, L Alvarez-González, N Pavón-Fuentes, R Macías-González, T Serrano-Sánchez, J C Rosillo-Martí, Y Coro-Grave de Peralta, Y Bauza-Calderín, M Brione. [Lesions in the pars compacta substantiae nigra and the subthalamic nucleus modify the density of muscarinic receptors in different nuclei of the basal ganglia]. Revista de neurologia. vol 38. issue 2. 2004-05-25. PMID:14752710. |
several studies that has focused to the dopaminergic transmission in the basal ganglia in parkinsonian condition, but only a few article has taking into account the imbalance between dopaminergic and cholinergic transmission. |
2004-05-25 |
2023-08-12 |
Not clear |
| K Stiasny-Kolster, W Magerl, W H Oertel, J C Möller, R-D Treed. Static mechanical hyperalgesia without dynamic tactile allodynia in patients with restless legs syndrome. Brain : a journal of neurology. vol 127. issue Pt 4. 2004-05-20. PMID:14985260. |
the reduction of hyperalgesia in rls patients by long-term dopaminergic treatment suggests that the pathophysiology of rls includes disturbed supraspinal pain modulation involving the basal ganglia and/or descending dopaminergic pathways. |
2004-05-20 |
2023-08-12 |
human |
| J Srinivasan, W J Schmid. Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion: effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 1. 2004-04-30. PMID:14714212. |
though this is to some extent understood, the longstanding effects of noradrenergic lesion on dopaminergic neurons of the basal ganglia and in parkinsonian behavior is not known. |
2004-04-30 |
2023-08-12 |
rat |
| Henk J Groenewegen, Odile A van den Heuvel, Danielle C Cath, P Voorn, Dick J Veltma. Does an imbalance between the dorsal and ventral striatopallidal systems play a role in Tourette's syndrome? A neuronal circuit approach. Brain & development. vol 25 Suppl 1. 2004-04-15. PMID:14980365. |
a conclusion of this overview of the anatomical organization of the basal ganglia is that via dopaminergic pathways limbic-relation information can influence the expression of (fragments of) motor and behavioral repertoires. |
2004-04-15 |
2023-08-12 |
Not clear |
| L W Chen, K K L Yung, Y S Cha. Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease. Current drug targets. vol 5. issue 2. 2004-04-13. PMID:15011953. |
in addition, nk receptors, namely nk-1 and nk-3 receptors, are abundantly localized in dopaminergic and cholinergic neurons of the basal ganglia, indicating that these neurons are under the physiological regulation of nks. |
2004-04-13 |
2023-08-12 |
mouse |
| Volker Sturm, Doris Lenartz, Athanasios Koulousakis, Harald Treuer, Karl Herholz, Johannes Christian Klein, Joachim Klosterkötte. The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders. Journal of chemical neuroanatomy. vol 26. issue 4. 2004-04-02. PMID:14729131. |
as a central relay-structure between amygdala, basal ganglia, mesolimbic dopaminergic areas, mediodorsal thalamus and prefrontal cortex, the accumbens nucleus seems to play a modulatory role in information flow from the amygdaloid complex to the latter areas. |
2004-04-02 |
2023-08-12 |
Not clear |
| Masaki Ohn. The dopaminergic system in attention deficit/hyperactivity disorder. Congenital anomalies. vol 43. issue 2. 2004-03-30. PMID:12893970. |
the majority of the functional brain imaging studies in both clinical and experimental settings support hypofunction of the basal ganglia which receive abundant dopaminergic afferent. |
2004-03-30 |
2023-08-12 |
mouse |
| Jean-Jacques Bacci, Philippe Kachidian, Lydia Kerkerian-Le Goff, Pascal Sali. Intralaminar thalamic nuclei lesions: widespread impact on dopamine denervation-mediated cellular defects in the rat basal ganglia. Journal of neuropathology and experimental neurology. vol 63. issue 1. 2004-03-10. PMID:14748558. |
altogether, these data reveal a major antagonistic influence of thalamic and dopaminergic afferents onto the basal ganglia and suggest that degeneration of thalamic neurons in parkinson disease may represent an important factor counteracting expression of the defects associated with the dopamine denervation. |
2004-03-10 |
2023-08-12 |
rat |
| Claire Soudais, Nadia Skander, Eric J Kreme. Long-term in vivo transduction of neurons throughout the rat CNS using novel helper-dependent CAV-2 vectors. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 2. 2004-02-24. PMID:14688208. |
one year after striatal injections in the rat brain, we found stable, high-level expression in striatal neurons, ~50% of the dopaminergic neurons of the substantia nigra, and the cholinergic neurons in the basal nuclei of meynert. |
2004-02-24 |
2023-08-12 |
rat |
| Michael J Marino, Ornella Valenti, P Jeffrey Con. Glutamate receptors and Parkinson's disease: opportunities for intervention. Drugs & aging. vol 20. issue 5. 2004-02-19. PMID:12696997. |
the resulting loss of striatal dopaminergic tone is believed to underlie a series of changes in the circuitry of the basal ganglia that ultimately lead to severe motor disturbances due to excessive basal ganglia outflow. |
2004-02-19 |
2023-08-12 |
Not clear |
| Jiang-Fan Chen, Silva Fredduzzi, Elena Bastia, Liqun Yu, Rosario Moratalla, Ennio Ongini, Michael A Schwarzschil. Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease. Neurology. vol 61. issue 11 Suppl 6. 2004-02-11. PMID:14663016. |
the unique neuronal localization of the adenosine a2a receptor in the basal ganglia and its extensive interactions with dopaminergic and glutamatergic systems led the authors to investigate a potential role of the a2a receptor in the development of behavioral sensitization in response to repeated dopaminergic stimulation. |
2004-02-11 |
2023-08-12 |
mouse |
| J A Obeso, M Rodriguez-Oroz, C Marin, F Alonso, I Zamarbide, J L Lanciego, M Rodriguez-Dia. The origin of motor fluctuations in Parkinson's disease: importance of dopaminergic innervation and basal ganglia circuits. Neurology. vol 62. issue 1 Suppl 1. 2004-02-04. PMID:14718677. |
the origin of motor fluctuations in parkinson's disease: importance of dopaminergic innervation and basal ganglia circuits. |
2004-02-04 |
2023-08-12 |
Not clear |
| J A Obeso, M Rodriguez-Oroz, C Marin, F Alonso, I Zamarbide, J L Lanciego, M Rodriguez-Dia. The origin of motor fluctuations in Parkinson's disease: importance of dopaminergic innervation and basal ganglia circuits. Neurology. vol 62. issue 1 Suppl 1. 2004-02-04. PMID:14718677. |
therefore, both the magnitude and duration of the motor response are a function of the degree of motor severity, which is primarily governed by the loss of tonic dopaminergic activity and disruption of basal ganglia homeostatic mechanisms among which the stn-gpe/gpi circuits play a fundamental role. |
2004-02-04 |
2023-08-12 |
Not clear |