| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Siegert, E Bahn, M L Kramer, W J Schulz-Schaeffer, J W Hewett, X O Breakefield, J C Hedreen, K M Rostas. TorsinA expression is detectable in human infants as young as 4 weeks old. Brain research. Developmental brain research. vol 157. issue 1. 2005-08-12. PMID:15939081. |
expression of torsina protein was detectable beginning at 4 to 8 weeks of age postnatally in the cerebellum (purkinje cells), substantia nigra (dopaminergic neurons), hippocampus and basal ganglia. |
2005-08-12 |
2023-08-12 |
human |
| S J López-Pérez, P Vergara, J P Ventura-Valenzuela, M E Ureña-Guerrero, J Segovia, C Beas-Zárat. Modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 4. 2005-08-01. PMID:15927757. |
results indicate that an over-stimulation of the glutamatergic system by neonatal exposure to a high glutamate concentration induces a partial loss in th-positive neurons in the sn and an important reduction in dopaminergic markers expression in the striatum, suggesting that early excitotoxicity could contribute to developmental alterations in the nigrostriatal pathway, which may be associated with various disorders of the basal ganglia. |
2005-08-01 |
2023-08-12 |
rat |
| Séverine Perbal, Bernard Deweer, Bernard Pillon, Marie Vidailhet, Bruno Dubois, Viviane Poutha. Effects of internal clock and memory disorders on duration reproductions and duration productions in patients with Parkinson's disease. Brain and cognition. vol 58. issue 1. 2005-07-21. PMID:15878725. |
patients with parkinson's disease (pd) exhibit deficits in perceptual and motor timing as well as impairments in memory and attentional processes that are related to dysfunction of dopaminergic systems in the basal ganglia. |
2005-07-21 |
2023-08-12 |
human |
| Marco Tettamanti, Andrea Moro, Cristina Messa, Rosa M Moresco, Giovanna Rizzo, Assunta Carpinelli, Mario Matarrese, Ferruccio Fazio, Daniela Peran. Basal ganglia and language: phonology modulates dopaminergic release. Neuroreport. vol 16. issue 4. 2005-06-13. PMID:15729145. |
basal ganglia and language: phonology modulates dopaminergic release. |
2005-06-13 |
2023-08-12 |
human |
| Arash Rassoulpour, Hui-Qiu Wu, Sergi Ferre, Robert Schwarc. Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum. Journal of neurochemistry. vol 93. issue 3. 2005-06-03. PMID:15836634. |
precise regulation of dopaminergic activity is of obvious importance for the physiology and pathology of basal ganglia. |
2005-06-03 |
2023-08-12 |
rat |
| L M F Doyle, A A Kühn, M Hariz, A Kupsch, G-H Schneider, P Brow. Levodopa-induced modulation of subthalamic beta oscillations during self-paced movements in patients with Parkinson's disease. The European journal of neuroscience. vol 21. issue 5. 2005-05-27. PMID:15813950. |
these findings suggest that the beta erd recorded in the stn area reflects motor-preparative processes that are at least partly dependent on dopaminergic activity within the basal ganglia. |
2005-05-27 |
2023-08-12 |
Not clear |
| Svenja Happe, Martin Sommer, Johannes Meller, Claudia Trenkwalder, Walter Paulu. Dyskinesias due to intravenous apomorphine abuse in a patient without basal ganglia disorder. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 1. 2005-05-09. PMID:15390037. |
dyskinesias are known to occur in many patients with parkinson's disease treated with dopaminergic drugs but to date, drug-induced dyskinesias have not been observed in humans with no underlying basal ganglia disorder. |
2005-05-09 |
2023-08-12 |
Not clear |
| Kevin C F Fone, David J Nut. Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder. Current opinion in pharmacology. vol 5. issue 1. 2005-05-04. PMID:15661631. |
however, recent advances in molecular genetics and brain imaging implicate dopaminergic hypofunction in the frontal lobes and basal ganglia in adhd. |
2005-05-04 |
2023-08-12 |
Not clear |
| Elisa Messina, Vanna Micheli, Alessandro Giacomell. Guanine nucleotide depletion induces differentiation and aberrant neurite outgrowth in human dopaminergic neuroblastoma lines: a model for basal ganglia dysfunction in Lesch-Nyhan disease. Neuroscience letters. vol 375. issue 2. 2005-04-22. PMID:15670649. |
guanine nucleotide depletion induces differentiation and aberrant neurite outgrowth in human dopaminergic neuroblastoma lines: a model for basal ganglia dysfunction in lesch-nyhan disease. |
2005-04-22 |
2023-08-12 |
human |
| V Pedersen, W J Schmid. Immediate early gene expression in rat basal ganglia after destruction of the dopaminergic system. Neurotoxicity research. vol 2. issue 1. 2005-04-04. PMID:15545003. |
immediate early gene expression in rat basal ganglia after destruction of the dopaminergic system. |
2005-04-04 |
2023-08-12 |
rat |
| John D Salamone, Brian B Carlson, Clifford Rios, Elizabeth Lentini, Merce Correa, Ania Wisniecki, Adrienne Bet. Dopamine agonists suppress cholinomimetic-induced tremulous jaw movements in an animal model of Parkinsonism: tremorolytic effects of pergolide, ropinirole and CY 208-243. Behavioural brain research. vol 156. issue 2. 2005-03-07. PMID:15582103. |
together with previous studies, the present results suggest that cholinomimetic-induced jaw movements in rats can be used to characterize dopaminergic antiparkinsonian agents and to investigate the basal ganglia circuits involved in the generation of tremulous movements. |
2005-03-07 |
2023-08-12 |
human |
| Peter Teismann, Jörg B Schul. Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15338271. |
parkinson's disease (pd) is a frequent neurological disorder of the basal ganglia, which is characterized by the progressive loss of dopaminergic neurons mainly in the substantia nigra pars compacta (snpc). |
2005-03-04 |
2023-08-12 |
Not clear |
| J Srinivasan, Werner J Schmid. The effect of the alpha2-adrenoreceptor antagonist idazoxan against 6-hydroxydopamine-induced Parkinsonism in rats: multiple facets of action? Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 6. 2005-02-22. PMID:15118809. |
since dopaminergic and serotonergic mechanisms are thought to account for the anti-cataleptic/anti-parkinsonian property of idazoxan, dopamine, 5-hydroxytryptamine (5-ht) and its metabolites in the regions of the basal ganglia and prefrontal cortex were analysed by hplc. |
2005-02-22 |
2023-08-12 |
rat |
| Matteo Marti, Flora Mela, Carlo Veronesi, Remo Guerrini, Severo Salvadori, Mauro Federici, Nicola B Mercuri, Anna Rizzi, Gianfranco Franchi, Lorenzo Beani, Clementina Bianchi, Michele Morar. Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 30. 2005-02-15. PMID:15282268. |
nigrostriatal dopaminergic cells, which express n/ofq peptide (nop) receptors, are located in the substantia nigra pars compacta and extend their dendrites in the substantia nigra pars reticulata, thereby modulating the basal ganglia output neurons. |
2005-02-15 |
2023-08-12 |
mouse |
| Ulrike Sommer, Thomas Hummel, Katja Cormann, Antje Mueller, Johannes Frasnelli, Joachim Kropp, Heinz Reichman. Detection of presymptomatic Parkinson's disease: combining smell tests, transcranial sonography, and SPECT. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 10. 2005-02-14. PMID:15390014. |
longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop pd in the future. |
2005-02-14 |
2023-08-12 |
Not clear |
| H Sienkiewicz-Jarosz, A Scinska, W Kuran, D Ryglewicz, A Rogowski, E Wrobel, A Korkosz, A Kukwa, W Kostowski, P Bienkowsk. Taste responses in patients with Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 76. issue 1. 2005-02-08. PMID:15607993. |
preclinical studies indicate that dopaminergic transmission in the basal ganglia may be involved in processing of both pleasant and unpleasant stimuli. |
2005-02-08 |
2023-08-12 |
Not clear |
| Sandrine Thuret, Kambiz N Alavian, Martin Gassmann, C Kent Lloyd, Simone M Smits, Marten P Smidt, Rüdiger Klein, Richard H Dyck, Horst H Simo. The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. Journal of neurochemistry. vol 91. issue 6. 2005-01-21. PMID:15584907. |
the distribution of dopaminergic cell bodies in the midbrain, the expression of numerous genes specific to mesencephalic dopaminergic neurons, and the axonal projection to the basal ganglia all appeared normal. |
2005-01-21 |
2023-08-12 |
mouse |
| A Biraben, F Semah, M-J Ribeiro, G Douaud, P Remy, A Depauli. PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy. Neurology. vol 63. issue 1. 2004-12-21. PMID:15249613. |
studies in animal models and epileptic patients have suggested that circuits of the basal ganglia may control epileptic seizures and that striatal dopaminergic transmission plays a key role in seizure interruption. |
2004-12-21 |
2023-08-12 |
Not clear |
| R Djaldetti, A Shifrin, Z Rogowski, E Sprecher, E Melamed, D Yarnitsk. Quantitative measurement of pain sensation in patients with Parkinson disease. Neurology. vol 62. issue 12. 2004-12-01. PMID:15210877. |
experimental studies and clinical evidence indicate involvement of basal ganglia and dopaminergic pathways in central pain processing. |
2004-12-01 |
2023-08-12 |
Not clear |
| Ranjita Betarbet, J Timothy Greenamyr. Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP. Experimental neurology. vol 189. issue 2. 2004-10-28. PMID:15380489. |
in this study, we simultaneously analyzed the regulation of d1 and d2 dopamine receptors and levels of the neuropeptides, substance p, and enkephalin (enk) in various basal ganglia nuclei following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic denervation of striatum in nonhuman primates. |
2004-10-28 |
2023-08-12 |
monkey |