| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Craig Denis Hardman, Jasmine Monica Henderson, David Isaac Finkelstein, Malcolm Kenneth Horne, George Paxinos, Glenda Margaret Hallida. Comparison of the basal ganglia in rats, marmosets, macaques, baboons, and humans: volume and neuronal number for the output, internal relay, and striatal modulating nuclei. The Journal of comparative neurology. vol 445. issue 3. 2002-05-03. PMID:11920704. |
the reduction in snd neurons in humans suggests less dopaminergic regulation of the basal ganglia system compared with other species. |
2002-05-03 |
2023-08-12 |
rat |
| Thomas Wichmann, Michele A Kliem, Jesus Soare. Slow oscillatory discharge in the primate basal ganglia. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826081. |
oscillations with periods in the multisecond range have previously been recorded in basal ganglia neurons of awake paralyzed rats, and in these animals were shown to be increased by systemic dopaminergic stimulation, but not altered by depletion of the nigrostriatal dopamine supply. |
2002-03-26 |
2023-08-12 |
rat |
| Thomas Wichmann, Michele A Kliem, Jesus Soare. Slow oscillatory discharge in the primate basal ganglia. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826081. |
to determine whether oscillations with frequencies below 0.5 hz also exist in the primate basal ganglia, the spontaneous neuronal activity in the subthalamic nucleus (stn) and in the external and internal segments of the globus pallidus (gpe and gpi, respectively) was recorded with standard extracellular recording methods in two animals before and after treatment with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
2002-03-26 |
2023-08-12 |
rat |
| G Kunikowska, P Jenne. 6-Hydroxydopamine-lesioning of the nigrostriatal pathway in rats alters basal ganglia mRNA for copper, zinc- and manganese-superoxide dismutase, but not glutathione peroxidase. Brain research. vol 922. issue 1. 2002-02-19. PMID:11730701. |
the significant changes in cu,zn-sod and mn-sod mrna indicate that sod is primarily expressed by dopaminergic neurons of the nigrostriatal pathway, and that the mn-sod gene appears to be inducible in rat basal ganglia in response to both physical and chemical damage 5 weeks after 6-ohda-lesioning. |
2002-02-19 |
2023-08-12 |
rat |
| M B O'Byrne, J P Bolam, J J Hanley, K F Tipto. Tyrosine-hydroxylase immunoreactive cells in the rat striatum following treatment with MPP+. Advances in experimental medicine and biology. vol 483. 2002-01-29. PMID:11787621. |
within the basal ganglia, the dopaminergic cells are located in the substantia nigra pars compacta, and project to the striatum. |
2002-01-29 |
2023-08-12 |
rat |
| E C Cooper, E Harrington, Y N Jan, L Y Ja. M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11739564. |
in the basal ganglia, we find kcnq2n immunoreactivity on somata of dopaminergic and parvalbumin (pv)-positive (presumed gabaergic) cells of the substantia nigra, cholinergic large aspiny neurons of the striatum, and gabaergic and cholinergic neurons of the globus pallidus. |
2002-01-23 |
2023-08-12 |
mouse |
| F Bibbiani, J D Oh, T N Chas. Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models. Neurology. vol 57. issue 10. 2002-01-17. PMID:11723272. |
serotoninergic transmission in the basal ganglia is known to influence dopaminergic mechanisms and motor function. |
2002-01-17 |
2023-08-12 |
Not clear |
| C R Bjarkam, J C Sørensen, N A Sunde, F A Geneser, K Ostergaar. New strategies for the treatment of Parkinson's disease hold considerable promise for the future management of neurodegenerative disorders. Biogerontology. vol 2. issue 3. 2002-01-04. PMID:11708721. |
parkinson's disease is characterized by a massive loss of dopaminergic neurons in the substantia nigra, leading to severe functional disturbance of the neuronal circuitry in the basal ganglia. |
2002-01-04 |
2023-08-12 |
Not clear |
| M A Berger, M C Defagot, M J Villar, M C Antonell. D4 dopamine and metabotropic glutamate receptors in cerebral cortex and striatum in rat brain. Neurochemical research. vol 26. issue 4. 2002-01-02. PMID:11495344. |
the characterization of the functional interactions between the metabotropic glutamate receptors (mglur) and the dopaminergic (dr) receptors in the corticostriatal projections may provide a possible interpretation of synaptic events in the basal ganglia. |
2002-01-02 |
2023-08-12 |
rat |
| R R Gainetdinov, A R Mohn, L M Bohn, M G Caro. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 20. 2001-12-04. PMID:11572967. |
these findings support the concept of a reciprocal functional interaction between dopamine and glutamate in the basal ganglia and suggest that agents modulating glutamatergic transmission may represent an approach to manage conditions associated with dopaminergic dysfunction. |
2001-12-04 |
2023-08-12 |
mouse |
| P Castelnau, M Zilbovicius, M J Ribeiro, L Hertz-Pannier, H Ogier, P Evrar. Striatal and pontocerebellar hypoperfusion in Hallervorden-Spatz syndrome. Pediatric neurology. vol 25. issue 2. 2001-10-25. PMID:11551749. |
dopaminergic function of the basal ganglia, which was assessed based on visual- analysis of fixation of 18f-labeled fluoro-levodopa, was normal. |
2001-10-25 |
2023-08-12 |
Not clear |
| R A Jeyasingham, A L Baird, A Meldrum, S B Dunnet. Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat. Brain research bulletin. vol 55. issue 4. 2001-10-18. PMID:11543955. |
lateralised motor deficits associated with basal ganglia dysfunction were compared in separate groups of rats receiving unilateral 6-hydroxydopamine-induced lesions of the dopaminergic nigrostriatal pathway, quinolinic acid-induced lesions of the striatum, or sham control injections. |
2001-10-18 |
2023-08-12 |
rat |
| S J Crocker, N Wigle, P Liston, C S Thompson, C J Lee, D Xu, S Roy, D W Nicholson, D S Park, A MacKenzie, R G Korneluk, G S Robertso. NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease. The European journal of neuroscience. vol 14. issue 2. 2001-10-11. PMID:11553289. |
parkinson's disease (pd) is a progressive neurodegenerative disorder of the basal ganglia, associated with the inappropriate death of dopaminergic neurons of the substantia nigra pars compacta (snc). |
2001-10-11 |
2023-08-12 |
rat |
| T H Rammsayer, J Hennig, A Haag, N Lang. Effects of noradrenergic activity on temporal information processing in humans. The Quarterly journal of experimental psychology. B, Comparative and physiological psychology. vol 54. issue 3. 2001-10-04. PMID:11547514. |
temporal processing of durations in the range of seconds or more is mediated by working-memory mechanisms whereas processing of brief durations in the range of milliseconds appears to be beyond cognitive control and modulated by dopaminergic activity in the basal ganglia. |
2001-10-04 |
2023-08-12 |
human |
| R L Skeel, B Crosson, S E Nadeau, J Algina, R M Bauer, E B Fennel. Basal ganglia dysfunction, working memory, and sentence comprehension in patients with Parkinson's disease. Neuropsychologia. vol 39. issue 9. 2001-09-20. PMID:11516448. |
to investigate the role of the basal ganglia in working memory and sentence comprehension, 14 patients with parkinson's disease (pd) were administered experimental measures of semantic and phonological working memory, and a measure of sentence comprehension, while receiving dopaminergic medications and after a period of withdrawal from these medications. |
2001-09-20 |
2023-08-12 |
human |
| M Quik, Y Polonskaya, J M Kulak, J M McIntos. Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466420. |
these findings may indicate that most or all of (125)i-alpha-ctxmii-labeled nachr subtypes in the basal ganglia are present on nigrostriatal dopaminergic neurons, in contrast to (125)i-epibatidine sites. |
2001-08-16 |
2023-08-12 |
monkey |
| R M Kirrane, L J Sieve. New perspectives on schizotypal personality disorder. Current psychiatry reports. vol 2. issue 1. 2001-08-09. PMID:11122934. |
furthermore, schizotypal patients appear to show less susceptibility to psychotic symptoms, in part perhaps because of better buffered subcortical dopaminergic activity as suggested by recent data from a spect/amphetamine paradigm, glucose metabolic study, and structural studies of basal ganglia. |
2001-08-09 |
2023-08-12 |
Not clear |
| S L Castro, M J Zigmon. Stress-induced increase in extracellular dopamine in striatum: role of glutamatergic action via N-methyl-D-aspartate receptors in substantia nigra. Brain research. vol 901. issue 1-2. 2001-08-02. PMID:11368949. |
there is considerable support for an influence of excitatory amino acids released from corticofugal neurons on dopaminergic activity in the basal ganglia. |
2001-08-02 |
2023-08-12 |
Not clear |
| K Mukhida, K A Baker, D Sadi, I Mende. Enhancement of sensorimotor behavioral recovery in hemiparkinsonian rats with intrastriatal, intranigral, and intrasubthalamic nucleus dopaminergic transplants. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331381. |
these results suggest that restoration of dopaminergic activity to multiple basal ganglia targets, such as the st and sn, or the st and stn, promotes a more complete functional recovery of complex sensorimotor behaviors. |
2001-06-21 |
2023-08-12 |
rat |
| K Mukhida, K A Baker, D Sadi, I Mende. Enhancement of sensorimotor behavioral recovery in hemiparkinsonian rats with intrastriatal, intranigral, and intrasubthalamic nucleus dopaminergic transplants. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331381. |
a multitarget transplant strategy aimed at optimizing dopaminergic reinnervation of the basal ganglia may be crucial in improving clinical outcomes in pd patients. |
2001-06-21 |
2023-08-12 |
rat |