| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Audrey Maillet, Alexandre Krainik, Bettina Debû, Irène Troprès, Christelle Lagrange, Stéphane Thobois, Pierre Pollak, Serge Pint. Levodopa effects on hand and speech movements in patients with Parkinson's disease: a FMRI study. PloS one. vol 7. issue 10. 2013-06-11. PMID:23056337. |
our results question both the role of the basal ganglia system in speech production and the modulation of task-dependent cerebral networks by dopaminergic treatment. |
2013-06-11 |
2023-08-12 |
Not clear |
| Sarah Jesse, Jan Kassubek, Hans-Peter Müller, Albert C Ludolph, Alexander Unrat. Signal alterations of the basal ganglia in the differential diagnosis of Parkinson's disease: a retrospective case-controlled MRI data bank analysis. BMC neurology. vol 12. 2013-06-06. PMID:23273141. |
based upon the acquainted loss of dopaminergic neurons in the substantia nigra in parkinson's disease (pd), we hypothesised changes in magnetic resonance imaging signal intensities of the basal ganglia to be useful as an additional technical tool in the diagnostic work-up. |
2013-06-06 |
2023-08-12 |
Not clear |
| Paul R Sanberg, Cecilia Vindrola-Padros, R Douglas Shytl. Translating laboratory discovery to the clinic: from nicotine and mecamylamine to Tourette's, depression, and beyond. Physiology & behavior. vol 107. issue 5. 2013-05-17. PMID:22776623. |
the early development of novel nicotinic drugs for tourette's and depression was a very long journey in discovery, which began with basic behavioral neuroscience studies aimed at understanding how cholinergic and dopaminergic systems interact in the basal ganglia to control goal directed movement. |
2013-05-17 |
2023-08-12 |
Not clear |
| Nicholas J Strausfeld, Frank Hirt. Deep homology of arthropod central complex and vertebrate basal ganglia. Science (New York, N.Y.). vol 340. issue 6129. 2013-04-24. PMID:23580521. |
in the substructures of both the central complex and basal ganglia, network connectivity and neuronal activity mediate control mechanisms in which inhibitory (gabaergic) and modulatory (dopaminergic) circuits facilitate the regulation and release of adaptive behaviors. |
2013-04-24 |
2023-08-12 |
Not clear |
| Tao Wu, Mark Hallet. The cerebellum in Parkinson's disease. Brain : a journal of neurology. vol 136. issue Pt 3. 2013-04-23. PMID:23404337. |
pathological changes in the cerebellum might be induced by dopaminergic degeneration, abnormal drives from the basal ganglia and dopaminergic treatment, and may account for some clinical symptoms in parkinson's disease. |
2013-04-23 |
2023-08-12 |
Not clear |
| OrhanTansel Korkmaz, Hakan Ay, Emel Ulupinar, Neşe Tunçe. Vasoactive intestinal peptide enhances striatal plasticity and prevents dopaminergic cell loss in Parkinsonian rats. Journal of molecular neuroscience : MN. vol 48. issue 3. 2013-04-19. PMID:22544516. |
dopaminergic inputs from the snc innervate the medium spiny neurons of the striatum and modulate the spontaneous activity of the primary output nuclei of the basal ganglia, globus pallidus interna, and substantia nigra pars reticulata. |
2013-04-19 |
2023-08-12 |
rat |
| Ulrich Ettinger, Philip J Corr, Ardeshier Mofidi, Steven C R Williams, Veena Kumar. Dopaminergic basis of the psychosis-prone personality investigated with functional magnetic resonance imaging of procedural learning. Frontiers in human neuroscience. vol 7. 2013-04-19. PMID:23596404. |
as da is a key transmitter in the basal ganglia, and the thalamus contains the highest levels of drd2 receptors of all extrastriatal regions, our results support a dopaminergic basis of psychosis-proneness as measured by the epq-r psychoticism. |
2013-04-19 |
2023-08-12 |
human |
| Arthur Leblois, David J Perke. Striatal dopamine modulates song spectral but not temporal features through D1 receptors. The European journal of neuroscience. vol 35. issue 11. 2013-04-04. PMID:22594943. |
the activity of midbrain dopaminergic neurons and their projection to the basal ganglia (bg) are thought to play a critical role in the acquisition of motor skills through reinforcement learning, as well as in the expression of learned motor behaviors. |
2013-04-04 |
2023-08-12 |
Not clear |
| Andrew H Moberly, Lindsey A Czarnecki, Joseph Pottackal, Tom Rubinstein, Daniel J Turkel, Marley D Kass, John P McGan. Intranasal exposure to manganese disrupts neurotransmitter release from glutamatergic synapses in the central nervous system in vivo. Neurotoxicology. vol 33. issue 5. 2013-03-21. PMID:22542936. |
the commonality of mn's action between glutamatergic neurons in the olfactory bulb and dopaminergic neurons in the basal ganglia suggests that a disruption of neurotransmitter release may be a general consequence wherever mn accumulates in the brain and could underlie its pleiotropic effects. |
2013-03-21 |
2023-08-12 |
mouse |
| Gail D Tillman, Clifford S Calley, Timothy A Green, Virginia I Buhl, Melanie M Biggs, Jeffrey S Spence, Richard W Briggs, Robert W Haley, John Hart, Michael A Krau. Event-related potential patterns associated with hyperarousal in Gulf War illness syndrome groups. Neurotoxicology. vol 33. issue 5. 2013-03-21. PMID:22691951. |
syndromes 1 and 2, who have previously shown basal ganglia dysfunction, show significantly weaker p3a response to distractor stimuli, purported to indicate dysfunction of the dopaminergic contribution to their ability to inhibit distraction by irrelevant stimuli. |
2013-03-21 |
2023-08-12 |
Not clear |
| Noelia Granado, Sara Ares-Santos, Rosario Moratall. Methamphetamine and Parkinson's disease. Parkinson's disease. vol 2013. 2013-03-12. PMID:23476887. |
the molecular basis of parkinson's disease is the loss of dopamine in the basal ganglia (caudate/putamen) due to the degeneration of dopaminergic neurons in the substantia nigra, which leads to the motor impairment characteristic of the disease. |
2013-03-12 |
2023-08-12 |
human |
| M J MacMahon, D G MacMaho. Management of Parkinson's disease in the acute hospital environment. The journal of the Royal College of Physicians of Edinburgh. vol 42. issue 2. 2013-03-11. PMID:22693703. |
however the objective for the vast majority of patients remains the maintenance of quality of life through the achievement of steady levels of dopaminergic stimulation within the target neurones of the basal ganglia. |
2013-03-11 |
2023-08-12 |
Not clear |
| Olivier Pauly, Seyed-Ahmad Ahmadi, Annika Plate, Kai Boetzel, Nassir Nava. Detection of substantia nigra echogenicities in 3D transcranial ultrasound for early diagnosis of Parkinson disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 15. issue Pt 3. 2013-01-29. PMID:23286161. |
parkinson's disease (pd) is a neurodegenerative movement disorder caused by decay of dopaminergic cells in the substantia nigra (sn), which are basal ganglia residing within the midbrain area. |
2013-01-29 |
2023-08-12 |
Not clear |
| Daphna Sourani, Renana Eitan, Noam Gordon, Gadi Goelma. The habenula couples the dopaminergic and the serotonergic systems: application to depression in Parkinson's disease. The European journal of neuroscience. vol 36. issue 6. 2013-01-09. PMID:22774942. |
within the framework of the monoamine deficiency hypothesis of depression, we propose that the dopaminergic and serotonergic systems are coupled by the lateral habenula, and argue that altered basal ganglia activity leads to lateral habenula hyperactivity, which in turn down-regulates the serotonergic system, resulting in depressive symptoms in patients with parkinson's disease. |
2013-01-09 |
2023-08-12 |
rat |
| Lucile Capuron, Giuseppe Pagnoni, Daniel F Drake, Bobbi J Woolwine, James R Spivey, Ronald J Crowe, John R Votaw, Mark M Goodman, Andrew H Mille. Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration. Archives of general psychiatry. vol 69. issue 10. 2012-12-13. PMID:23026954. |
dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration. |
2012-12-13 |
2023-08-12 |
Not clear |
| Carsten Holzmann, Désirée Dräger, Eilhard Mix, Alexander Hawlitschka, Veronica Antipova, Reiner Benecke, Andreas Wre. Effects of intrastriatal botulinum neurotoxin A on the behavior of Wistar rats. Behavioural brain research. vol 234. issue 1. 2012-12-07. PMID:22728288. |
central pathophysiological pathways of basal ganglia dysfunction imply a disturbed interaction of dopaminergic and cholinergic circuits. |
2012-12-07 |
2023-08-12 |
rat |
| Natasha Luquin, Salvador Sierra, Alberto J Rico, Virginia Gómez-Bautista, Elvira Roda, Lorena Conte-Perales, Rafael Franco, Peter McCormick, José L Labandeira-García, José L Lancieg. Unmasking adenosine 2A receptors (A2ARs) in monkey basal ganglia output neurons using cholera toxin subunit B (CTB). Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22659306. |
the a(2a)r has become a therapeutic target in parkinson disease due to its functional role in the striatum, capable of modulating dopaminergic neurotransmission in the basal ganglia. |
2012-11-29 |
2023-08-12 |
monkey |
| S Lopez, L Jouve, N Turle-Lorenzo, L Kerkerian-Legoff, P Salin, M Amalri. Antiparkinsonian action of a selective group III mGlu receptor agonist is associated with reversal of subthalamonigral overactivity. Neurobiology of disease. vol 46. issue 1. 2012-11-20. PMID:22245662. |
altogether, our results provide new evidence for the antiparkinsonian efficiency of group iii mglu receptor agonism, point to the regulation of the overactive subthalamo-nigral connection as a main site of action in an early stage of pd and underline the complex interplay between these receptors and the dopaminergic system to regulate basal ganglia function in control and pd conditions. |
2012-11-20 |
2023-08-12 |
rat |
| Stefano Meletti, Aglaia Vignoli, Francesca Benuzzi, Pietro Avanzini, Andrea Ruggieri, Matteo Pugnaghi, Paolo Nichelli, Maria Paola Canevin. Ictal involvement of the nigrostriatal system in subtle seizures of ring chromosome 20 epilepsy. Epilepsia. vol 53. issue 8. 2012-10-26. PMID:22738216. |
studies in animal models and patients with epilepsy have suggested that basal ganglia circuits may control epileptic seizures and that striatal dopaminergic transmission may play a role in seizure modulation and interruption. |
2012-10-26 |
2023-08-12 |
human |
| Amanda L Piquet, Kala Venkiteswaran, Neena I Marupudi, Matthew Berk, Thyagarajan Subramania. The immunological challenges of cell transplantation for the treatment of Parkinson's disease. Brain research bulletin. vol 88. issue 4. 2012-10-23. PMID:22521427. |
recent studies also show that dopaminergic cell transplants provide long-term neuromodulation in the basal ganglia that simulates the combined effects of oral dopaminergic therapy and surgical therapies like deep brain stimulation, the contemporary therapeutic approach to advanced pd. |
2012-10-23 |
2023-08-12 |
Not clear |