| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
neurochemical changes in cholinergic neurons in the striatum and ?-aminobutyric acid (gaba)ergic neurons in the midbrain, especially in the basal ganglia, have been examined following the intraperitoneal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), which is known to cause behavioral changes resembling those in parkinson's disease due to the destruction of nigro-striatal dopaminergic neurons. |
2012-10-02 |
2023-08-12 |
mouse |
| J P O'Callaghan, D B Miller, K R Pennypacke. Chronic dopaminergic signaling in the basal ganglia: a damage perspective on kinases and fos-related antigens. Addiction biology. vol 5. issue 3. 2012-10-02. PMID:20575854. |
chronic dopaminergic signaling in the basal ganglia: a damage perspective on kinases and fos-related antigens. |
2012-10-02 |
2023-08-12 |
Not clear |
| Thomas T Hill. Animal foraging and the evolution of goal-directed cognition. Cognitive science. vol 30. issue 1. 2012-10-02. PMID:21702807. |
the basal ganglia in higher vertebrates show the ability to transfer dopaminergic activity from unconditioned stimuli to conditioned stimuli. |
2012-10-02 |
2023-08-12 |
human |
| Terrence C Stewart, Trevor Bekolay, Chris Eliasmit. Learning to select actions with spiking neurons in the Basal Ganglia. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22319465. |
we expand our existing spiking neuron model of decision making in the cortex and basal ganglia to include local learning on the synaptic connections between the cortex and striatum, modulated by a dopaminergic reward signal. |
2012-10-02 |
2023-08-12 |
Not clear |
| Mark D Humphries, Mehdi Khamassi, Kevin Gurne. Dopaminergic Control of the Exploration-Exploitation Trade-Off via the Basal Ganglia. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22347155. |
dopaminergic control of the exploration-exploitation trade-off via the basal ganglia. |
2012-10-02 |
2023-08-12 |
Not clear |
| Teresa Morera-Herreras, Cristina Miguelez, Asier Aristieta, José Ángel Ruiz-Ortega, Luisa Uged. Endocannabinoid modulation of dopaminergic motor circuits. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22701427. |
there is substantial evidence supporting a role for the endocannabinoid system as a modulator of the dopaminergic activity in the basal ganglia, a forebrain system that integrates cortical information to coordinate motor activity regulating signals. |
2012-10-02 |
2023-08-12 |
Not clear |
| Teresa Morera-Herreras, Cristina Miguelez, Asier Aristieta, José Ángel Ruiz-Ortega, Luisa Uged. Endocannabinoid modulation of dopaminergic motor circuits. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22701427. |
these effects are mediated primarily through the cb(1) receptors that are densely located in the dopamine-enriched basal ganglia networks, suggesting that the motor effects of endocannabinoids are due, at least in part, to modulation of dopaminergic transmission. |
2012-10-02 |
2023-08-12 |
Not clear |
| Aliya L Frederick, Tommy P Saborido, Gregg D Stanwoo. Neurobehavioral phenotyping of G(αq) knockout mice reveals impairments in motor functions and spatial working memory without changes in anxiety or behavioral despair. Frontiers in behavioral neuroscience. vol 6. 2012-10-02. PMID:22723772. |
we observed significant increases in drug-induced locomotor activity in g(αq) knockout mice from the dopaminergic agonists but not mk-801, indicating that basal ganglia locomotor circuitry is largely intact in the absence of g(αq). |
2012-10-02 |
2023-08-12 |
mouse |
| George Stoica, Gina Lungu, Nicole L Bjorklund, Giulio Taglialatela, Xing Zhang, Veronica Chiu, Herbert H Hill, James O Schenk, Ian Murra. Potential role of α-synuclein in neurodegeneration: studies in a rat animal model. Journal of neurochemistry. vol 122. issue 4. 2012-09-27. PMID:22639889. |
these rats demonstrate progressive increases in α-syn in the brain mesencephalon followed by loss of dopaminergic terminals in the basal ganglia (bg) and motor impairments. |
2012-09-27 |
2023-08-12 |
human |
| Kelly A Meulendyke, Mikhail V Pletnikov, Elizabeth L Engle, Patrick M Tarwater, David R Graham, M Christine Zin. Early minocycline treatment prevents a decrease in striatal dopamine in an SIV model of HIV-associated neurological disease. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 2. 2012-09-24. PMID:22198699. |
da decline was not due to direct loss of dopaminergic projections to the basal ganglia as there was no difference in tyrosine hydroxylase, dopamine transporter, vesicular monoamine transporter 2 or synaptophysin between minocycline-treated and untreated macaques. |
2012-09-24 |
2023-08-12 |
Not clear |
| Fabrizio Benedett. Placebo-induced improvements: how therapeutic rituals affect the patient's brain. Journal of acupuncture and meridian studies. vol 5. issue 3. 2012-09-19. PMID:22682270. |
in the second case, dopaminergic activation in the striatum and neuronal changes in basal ganglia have been described. |
2012-09-19 |
2023-08-12 |
Not clear |
| Xianzhi Zeng, Huijuan Shen, Junpeng Zhao, Qing Cai, Congrong Wang, Qunyuan X. Long-term changes in morphology, D2R expression and targets of regenerated dopaminergic terminals in the striatum after a partial lesion in the substantia nigra in the rat. Brain research. vol 1450. 2012-09-14. PMID:22424788. |
the targeted change in regenerated dopaminergic terminals may disrupt the balance between the direct and indirect pathways in the basal ganglia, thereby resulting in the onset of pd symptoms. |
2012-09-14 |
2023-08-12 |
rat |
| Wei-Ning Xue, Yuan Wang, Shi-Ming He, Xue-Lian Wang, Jun-Ling Zhu, Guo-Dong Ga. SK- and h-current contribute to the generation of theta-like resonance of rat substantia nigra pars compacta dopaminergic neurons at hyperpolarized membrane potentials. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:22108680. |
the basal ganglia neurons receive comprehensive modulation arising from dopaminergic (da) neurons located in the substantia nigra pars compacta (snc), but how the oscillation is regulated in snc da neurons remains poorly understood. |
2012-09-04 |
2023-08-12 |
rat |
| Rachel Denyer, Michael R Dougla. Gene therapy for Parkinson's disease. Parkinson's disease. vol 2012. 2012-08-23. PMID:22619738. |
more radically, gene therapy could be used to correct the imbalances in basal ganglia circuitry associated with the symptoms of parkinson's disease, or to preserve or restore dopaminergic neurons lost during the disease process itself. |
2012-08-23 |
2023-08-12 |
Not clear |
| Marios Politis, Kit Wu, Clare Loane, Niall P Quinn, David J Brooks, Wolfgang H Oertel, Anders Björklund, Olle Lindvall, Paola Piccin. Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts. Science translational medicine. vol 4. issue 128. 2012-08-01. PMID:22491951. |
at 13 to 16 years after transplantation, dopaminergic innervation was restored to normal levels in basal ganglia and preserved in a number of extrabasal ganglia areas. |
2012-08-01 |
2023-08-12 |
Not clear |
| Miguel Schwartz, Sergiu Sabeta. An approach to the continuous dopaminergic stimulation in Parkinson's disease. The Israel Medical Association journal : IMAJ. vol 14. issue 3. 2012-07-10. PMID:22675859. |
dopaminergic neurons in the basal ganglia normally fire in a continuous manner, maintaining the striatal dopamine concentration at a relatively constant level. |
2012-07-10 |
2023-08-12 |
Not clear |
| Patricia A Broderick, Edwin H Kolodn. Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. Sensors (Basel, Switzerland). vol 11. issue 1. 2012-07-09. PMID:22346571. |
in the present studies, broderick probe(®) laurate biosensors and ldf laser sensors are placed in dorsal striatum (dstr) dopaminergic motor neurons in basal ganglia of brain in living animals; basal ganglia influence movement disorders such as those correlated with ais. |
2012-07-09 |
2023-08-12 |
Not clear |
| Alisson Menezes Araújo Lima, Fabiana de Campos Cordeiro Hirata, Gabriela Sales de Bruin, Rosa Maria Salani Mota, Veralice Meireles Sales de Brui. The influence of playing a non-reward game on motor ability and executive function in Parkinson's disease. Behavioural neurology. vol 25. issue 2. 2012-07-09. PMID:22530266. |
our results suggest a role for the reward system in the modulation of the dopaminergic function of the basal ganglia in these patients. |
2012-07-09 |
2023-08-12 |
Not clear |
| Maryka Quik, Susan Wonnacot. α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease. Pharmacological reviews. vol 63. issue 4. 2012-07-03. PMID:21969327. |
the rationale for such work stems from basic research findings that there is an extensive overlap in the organization and function of the nicotinic cholinergic and dopaminergic systems in the basal ganglia. |
2012-07-03 |
2023-08-12 |
Not clear |
| N R Ferreira, M Mitkovski, W Stühmer, L A Pardo, E A Del Be. Ether-à-go-go 1 (Eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion. Neurotoxicity research. vol 21. issue 3. 2012-06-26. PMID:22048886. |
ether-à-go-go 1 (eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion. |
2012-06-26 |
2023-08-12 |
rat |