| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dimitri Ryczko, Swantje Grätsch, François Auclair, Catherine Dubé, Saskia Bergeron, Michael H Alpert, Jackson J Cone, Mitchell F Roitman, Simon Alford, Réjean Dubu. Forebrain dopamine neurons project down to a brainstem region controlling locomotion. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 34. 2013-11-26. PMID:23918379. |
the contribution of dopamine (da) to locomotor control is traditionally attributed to ascending dopaminergic projections from the substantia nigra pars compacta and the ventral tegmental area to the basal ganglia, which in turn project down to the mesencephalic locomotor region (mlr), a brainstem region controlling locomotion in vertebrates. |
2013-11-26 |
2023-08-12 |
monkey |
| L Filippi, C Bruni, F Padovano, O Schillaci, G Simonett. The Value of Semi-Quantitative Analysis of 123I-FP-CIT SPECT in Evaluating Patients with Parkinson's Disease. The neuroradiology journal. vol 21. issue 4. 2013-11-26. PMID:24256955. |
qualitative visual assessment showed striatal dopaminergic (123)i-fp-cit uptake was significantly reduced in 60.4% (controlateral putamen to the symptoms), in 31.3% (caudate nucleus) and in 8.3% (ipsolateral basal ganglia to the symptoms). |
2013-11-26 |
2023-08-12 |
human |
| Christoph Scherfler, Regina Esterhammer, Michael Nocker, Philipp Mahlknecht, Heike Stockner, Boris Warwitz, Sabine Spielberger, Bernadette Pinter, Eveline Donnemiller, Clemens Decristoforo, Irene Virgolini, Michael Schocke, Werner Poewe, Klaus Sepp. Correlation of dopaminergic terminal dysfunction and microstructural abnormalities of the basal ganglia and the olfactory tract in Parkinson's disease. Brain : a journal of neurology. vol 136. issue Pt 10. 2013-11-25. PMID:24014521. |
correlation of dopaminergic terminal dysfunction and microstructural abnormalities of the basal ganglia and the olfactory tract in parkinson's disease. |
2013-11-25 |
2023-08-12 |
human |
| J A Priebe, P Rieckmann, S Lautenbache. [Central pain processing and Parkinson's disease. Epidemiology, physiology, and experimental results issuing pain processing]. Schmerz (Berlin, Germany). vol 26. issue 6. 2013-11-19. PMID:23052966. |
parkinson's disease (pd) is caused by degeneration of the dopaminergic neurons in the substantia nigra (sn) and a resulting dysfunction of the nigrostriatal pathways including the basal ganglia. |
2013-11-19 |
2023-08-12 |
Not clear |
| J A Priebe, P Rieckmann, S Lautenbache. [Central pain processing and Parkinson's disease. Epidemiology, physiology, and experimental results issuing pain processing]. Schmerz (Berlin, Germany). vol 26. issue 6. 2013-11-19. PMID:23052966. |
based on a review of the literature, it is postulated that dysfunction in endogenous pain inhibition caused by dopaminergic deficiency in the basal ganglia, especially in the striatum, but also in mesolimbic areas is a main pathophysiological mechanism involved in nociceptive abnormalities in pd. |
2013-11-19 |
2023-08-12 |
Not clear |
| Julien Pierre Dupuis, Michael Feyder, Cristina Miguelez, Liliana Garcia, Stéphanie Morin, Daniel Choquet, Eric Hosy, Erwan Bezard, Gilberto Fisone, Bernard H Bioulac, Jérôme Baufreto. Dopamine-dependent long-term depression at subthalamo-nigral synapses is lost in experimental parkinsonism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 36. 2013-11-15. PMID:24005286. |
impairments of synaptic plasticity are a hallmark of several neurological disorders, including parkinson's disease (pd) which results from the progressive loss of dopaminergic neurons of the substantia nigra pars compacta leading to abnormal activity within the basal ganglia (bg) network and pathological motor symptoms. |
2013-11-15 |
2023-08-12 |
rat |
| D N Voronkov, R M Khudoerkov, E L Dovedov. [Changes in neuroglial interactions in the cerebral nigrostriatal structures in a model of dopamine system dysfunction]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 113. issue 7. 2013-11-12. PMID:23994921. |
it has been supposed that the activation of astroglia by reserpine in a dopamine hypofunction model is caused by the dysfunction of the corticostriatal glutamatergic system as a result of inhibition of the dopaminergic transmission in the basal nuclei. |
2013-11-12 |
2023-08-12 |
rat |
| Satoshi Fujita, Risako Kato, Yilong Cui, Masanori Terakado, Kurando Suga, Noriaki Koshikawa, Masayuki Kobayash. Apomorphine-induced modulation of neural activities in the ventrolateral striatum of rats. Synapse (New York, N.Y.). vol 67. issue 7. 2013-11-07. PMID:23401143. |
the dopaminergic system in the ventrolateral portion of the striatum (svl), part of the basal ganglia, regulates orofacial movements; bilateral co-stimulation of both dopamine d1 -like and d2 -like receptors elicits repetitive jaw movements in rats. |
2013-11-07 |
2023-08-12 |
rat |
| Robert Adam, Alexander Leff, Nihal Sinha, Christopher Turner, Paul Bays, Bogdan Draganski, Masud Husai. Dopamine reverses reward insensitivity in apathy following globus pallidus lesions. Cortex; a journal devoted to the study of the nervous system and behavior. vol 49. issue 5. 2013-10-30. PMID:22721958. |
they demonstrate that reward insensitivity associated with basal ganglia dysfunction might be an important component of apathy that can be reversed by dopaminergic modulation. |
2013-10-30 |
2023-08-12 |
Not clear |
| Christin Y Sander, Jacob M Hooker, Ciprian Catana, Marc D Normandin, Nathaniel M Alpert, Gitte M Knudsen, Wim Vanduffel, Bruce R Rosen, Joseph B Mandevill. Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 27. 2013-09-26. PMID:23723346. |
these results can provide a basis for models that relate dopaminergic occupancies to hemodynamic changes in the basal ganglia. |
2013-09-26 |
2023-08-12 |
Not clear |
| Gail D Tillman, Clifford S Calley, Timothy A Green, Virginia I Buhl, Melanie M Biggs, Jeffrey S Spence, Richard W Briggs, Robert W Haley, Michael A Kraut, John Har. Visual event-related potentials as markers of hyperarousal in Gulf War illness: evidence against a stress-related etiology. Psychiatry research. vol 211. issue 3. 2013-09-09. PMID:23149040. |
although many factors may contribute to p3b amplitude differences - most notably depression and poor sleep quality, symptoms that are prevalent in the gw syndrome groups - our findings in context of previous studies on this population are consistent with the contention that dysfunction in cholinergic and dopaminergic neurotransmitter systems, and in white matter and basal ganglia may be contributing to impairments in gw veterans. |
2013-09-09 |
2023-08-12 |
Not clear |
| Yoshikazu Isomura, Takashi Takekawa, Rie Harukuni, Takashi Handa, Hidenori Aizawa, Masahiko Takada, Tomoki Fuka. Reward-modulated motor information in identified striatum neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 25. 2013-08-30. PMID:23785137. |
our results suggest that the direct and indirect pathway neurons cooperatively rather than antagonistically contribute to spatiotemporal control of voluntary movements, and that motor information is subcortically integrated with reward information through dopaminergic and other signals in the skeletomotor loop of the basal ganglia. |
2013-08-30 |
2023-08-12 |
rat |
| Changlei Xu, Junpeng Zhao, Yujun Liu, Xianzhi Zeng, Yan Jia, Ying Wang, Xiaohua Jiang, Qunyuan X. Dopaminergic axons preferentially innervate dendritic spines with hyperactive glutamatergic synapses in the rat striatum. Brain research. vol 1486. 2013-08-23. PMID:23010310. |
dopaminergic and glutamatergic afferents simultaneously innervate median spiny neurons (msns) and interact to mediate basal ganglia functions. |
2013-08-23 |
2023-08-12 |
rat |
| Paolo Calabresi, Massimiliano Di Filippo, Antongiulio Gallina, Yingfei Wang, Jeannette N Stankowski, Barbara Picconi, Valina L Dawson, Ted M Dawso. New synaptic and molecular targets for neuroprotection in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 1. 2013-08-21. PMID:22927178. |
moreover, we also discuss the possibility to target the cell death program parthanatos and the kinase lrrk2 in order to develop new putative neuroprotective agents for pd acting on dopaminergic nigral neurons as well as on other basal ganglia structures. |
2013-08-21 |
2023-08-12 |
Not clear |
| Lorraine V Kalia, Jonathan M Brotchie, Susan H Fo. Novel nondopaminergic targets for motor features of Parkinson's disease: review of recent trials. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 2. 2013-08-06. PMID:23225267. |
neurotransmitters other than dopamine are recognized as having modulatory roles within the basal ganglia and can influence the basal ganglia dopaminergic system to alter activity of the direct and indirect pathways. |
2013-08-06 |
2023-08-12 |
Not clear |
| I A Prescott, J O Dostrovsky, E Moro, M Hodaie, A M Lozano, W D Hutchiso. Reduced paired pulse depression in the basal ganglia of dystonia patients. Neurobiology of disease. vol 51. 2013-07-24. PMID:23201208. |
we found that there was less paired pulse depression of local field evoked potentials in the basal ganglia output nuclei of dystonia patients compared with parkinson's disease patients on dopaminergic medication. |
2013-07-24 |
2023-08-12 |
Not clear |
| Quincy J Almeida, Matt J N Brow. Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson's Disease? Frontiers in neurology. vol 4. 2013-07-24. PMID:23882254. |
based on the notion that the basal ganglia are associated with sensory deficits, the influence of dopaminergic replacement on sensory feedback conditions during bimanual coordination was also evaluated. |
2013-07-24 |
2023-08-12 |
human |
| Noelia Granado, Isabel Lastres-Becker, Sara Ares-Santos, Idaira Oliva, Eduardo Martin, Antonio Cuadrado, Rosario Moratall. Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum. Glia. vol 59. issue 12. 2013-07-08. PMID:21882243. |
oxidative stress that correlates with damage to nigrostriatal dopaminergic neurons and reactive gliosis in the basal ganglia is a hallmark of methamphetamine (meth) toxicity. |
2013-07-08 |
2023-08-12 |
Not clear |
| M Amalric, S Lopez, C Goudet, G Fisone, G Battaglia, F Nicoletti, J-P Pin, F C Ache. Group III and subtype 4 metabotropic glutamate receptor agonists: discovery and pathophysiological applications in Parkinson's disease. Neuropharmacology. vol 66. 2013-07-02. PMID:22664304. |
restoring the balance between excitatory and inhibitory circuits in the basal ganglia, following the loss of dopaminergic (da) neurons of the substantia nigra pars compacta, represents a major challenge to treat patients affected by parkinson's disease (pd). |
2013-07-02 |
2023-08-12 |
Not clear |
| Tomás R Guilart. Manganese neurotoxicity: new perspectives from behavioral, neuroimaging, and neuropathological studies in humans and non-human primates. Frontiers in aging neuroscience. vol 5. 2013-06-28. PMID:23805100. |
historically, studies on the effects of mn in humans and experimental animals have been concerned with effects on the basal ganglia and the dopaminergic system as it relates to movement abnormalities. |
2013-06-28 |
2023-08-12 |
human |