| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C C Chao, S H. Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Developmental neuroscience. vol 16. issue 3-4. 1995-05-05. PMID:7705222. |
exposure of neuronal cultures to tnf alpha for 5 days resulted in a 27% decrease in astrocyte glutamine synthetase and in a 50% inhibition of 3h-glutamate uptake, suggesting that the effect of tnf alpha indirectly involves glutamate metabolism. |
1995-05-05 |
2023-08-12 |
human |
| R A Swanson, S H Graha. Fluorocitrate and fluoroacetate effects on astrocyte metabolism in vitro. Brain research. vol 664. issue 1-2. 1995-04-24. PMID:7895052. |
correspondingly, fc and fa caused less than 30% reductions in glutamate uptake (p > 0.05), an important energy-dependent astrocyte function. |
1995-04-24 |
2023-08-12 |
Not clear |
| R A Swanson, S H Graha. Fluorocitrate and fluoroacetate effects on astrocyte metabolism in vitro. Brain research. vol 664. issue 1-2. 1995-04-24. PMID:7895052. |
carbon flux through the krebs cycle was assessed by measuring astrocyte glutamine production in the absence of exogenous glutamate or aspartate. |
1995-04-24 |
2023-08-12 |
Not clear |
| A Brand, C Richter-Landsberg, D Leibfrit. Multinuclear NMR studies on the energy metabolism of glial and neuronal cells. Developmental neuroscience. vol 15. issue 3-5. 1995-02-02. PMID:7805581. |
the 13c isotopomer ratio of glutamate and glutamine is different for pure astrocyte cultures. |
1995-02-02 |
2023-08-12 |
rat |
| R F Butterwort. Portal-systemic encephalopathy: a disorder of neuron-astrocytic metabolic trafficking. Developmental neuroscience. vol 15. issue 3-5. 1995-02-02. PMID:7805584. |
in particular, reuptake of the neurotransmitter glutamate into the perineuronal astrocyte is inhibited in pse resulting in glutamatergic synaptic dysregulation and potentially compromised astrocytic energy metabolism. |
1995-02-02 |
2023-08-12 |
rat |
| S T Wofchuk, R Rodnigh. Glutamate stimulates the phosphorylation of glial fibrillary acidic protein in slices of immature rat hippocampus via a metabotropic receptor. Neurochemistry international. vol 24. issue 6. 1995-01-03. PMID:7981632. |
phosphorylation of the astrocyte cell marker glial fibrillary acidic protein (gfap) in hippocampal slices from immature rats (10-16 days postnatal) was strongly stimulated by glutamate in the presence of ca2+. |
1995-01-03 |
2023-08-12 |
rat |
| C Matute, J M García-Barcina, R Miled. Expression of neurotransmitter receptors and Ca2+ channels in the adult fornix and optic nerve. Neuroreport. vol 5. issue 12. 1994-12-23. PMID:7948838. |
glutamate receptors were mainly of the ampa/kainate type and were expressed in astrocyte cultures from the regions studied, suggesting that the receptors are present at least in this type of glial cells in vivo. |
1994-12-23 |
2023-08-12 |
cattle |
| A S Bender, M D Norenber. The role of K+ influx on glutamate induced astrocyte swelling: effect of temperature. Acta neurochirurgica. Supplementum. vol 60. 1994-12-01. PMID:7976567. |
the role of k+ influx on glutamate induced astrocyte swelling: effect of temperature. |
1994-12-01 |
2023-08-12 |
Not clear |
| W L Maxwell, R Bullock, H Landholt, H Fujisaw. Massive astrocytic swelling in response to extracellular glutamate--a possible mechanism for post-traumatic brain swelling? Acta neurochirurgica. Supplementum. vol 60. 1994-12-01. PMID:7976621. |
after 90 minutes of glutamate perfusion, intermediate filament bundles and glycogen granules occur within the astrocyte cytoplasm. |
1994-12-01 |
2023-08-12 |
Not clear |
| W L Maxwell, R Bullock, H Landholt, H Fujisaw. Massive astrocytic swelling in response to extracellular glutamate--a possible mechanism for post-traumatic brain swelling? Acta neurochirurgica. Supplementum. vol 60. 1994-12-01. PMID:7976621. |
we suggest that astrocyte swelling serves to limit the diffusion of glutamate from the site of the lesion. |
1994-12-01 |
2023-08-12 |
Not clear |
| M A DeCoster, D L Youric. Development of glutamate-stimulated phosphatidylinositol metabolism in primary neuronal and astrocyte cultures. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 3. 1994-11-22. PMID:7942095. |
pure astrocyte cultures exhibited glutamate-stimulated phosphatidylinositol hydrolysis only at high concentrations (100-400 microm), indicating that these cells contribute little to the overall inositol phosphate accumulation measured in mixed neuronal cultures treated with low glutamate concentrations. |
1994-11-22 |
2023-08-12 |
Not clear |
| M A DeCoster, D L Youric. Development of glutamate-stimulated phosphatidylinositol metabolism in primary neuronal and astrocyte cultures. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 3. 1994-11-22. PMID:7942095. |
comparison of mixed neuronal cultures with and without antimitotic treatment revealed that increasing astrocyte number suppressed glutamate-stimulated responses, presumably via glutamate uptake. |
1994-11-22 |
2023-08-12 |
Not clear |
| G J Stephens, M B Djamgoz, G P Wilki. A patch clamp study of excitatory amino acid effects on cortical astrocyte subtypes in culture. Receptors & channels. vol 1. issue 1. 1994-10-10. PMID:7915947. |
electrophysiological effects of the excitatory amino acids (eaas) glutamate (glu) and kainate (ka) on membrane properties of confluent (> 7-9 day) astrocyte cultures were examined. |
1994-10-10 |
2023-08-12 |
Not clear |
| V Parpura, T A Basarsky, F Liu, K Jeftinija, S Jeftinija, P G Haydo. Glutamate-mediated astrocyte-neuron signalling. Nature. vol 369. issue 6483. 1994-07-19. PMID:7911978. |
elevation of astrocyte internal calcium was also sufficient to induce glutamate release. |
1994-07-19 |
2023-08-12 |
Not clear |
| D J Benos, S McPherson, B H Hahn, M A Chaikin, E N Benvenist. Cytokines and HIV envelope glycoprotein gp120 stimulate Na+/H+ exchange in astrocytes. The Journal of biological chemistry. vol 269. issue 19. 1994-06-22. PMID:8188658. |
we hypothesize that the resultant increase in intracellular ph with its concomitant changes in astrocyte membrane permeability properties produces an imbalance in the k+ and glutamate microenvironment of the neurons, leading to a rise in intraneuronal ca2+ and eventual neuronal dysfunction and/or demise. |
1994-06-22 |
2023-08-12 |
human |
| M Weller, A M Marini, F Finiels-Marlier, B Martin, S M Pau. MK-801 and memantine protect cultured neurons from glutamate toxicity induced by glutamate carboxypeptidase-mediated cleavage of methotrexate. European journal of pharmacology. vol 248. issue 4. 1994-06-15. PMID:7910141. |
the simulation of glutamate carboxypeptidase rescue from high-dose methotrexate in neuron astrocyte cocultures of rat cerebellum or cerebral cortex resulted in a selective, concentration-dependent neurotoxicity. |
1994-06-15 |
2023-08-12 |
rat |
| J A Kelleher, G A Gregory, P H Cha. Effect of fructose-1,6-bisphosphate on glutamate uptake and glutamine synthetase activity in hypoxic astrocyte cultures. Neurochemical research. vol 19. issue 2. 1994-06-14. PMID:7910381. |
effect of fructose-1,6-bisphosphate on glutamate uptake and glutamine synthetase activity in hypoxic astrocyte cultures. |
1994-06-14 |
2023-08-12 |
Not clear |
| M L Brines, R J Robbin. Glutamate up-regulates alpha 1 and alpha 2 subunits of the sodium pump in astrocytes of mixed telencephalic cultures but not in pure astrocyte cultures. Brain research. vol 631. issue 1. 1994-03-04. PMID:7905355. |
glutamate up-regulates alpha 1 and alpha 2 subunits of the sodium pump in astrocytes of mixed telencephalic cultures but not in pure astrocyte cultures. |
1994-03-04 |
2023-08-12 |
Not clear |
| S Miller, P B Nunn, R J Bridge. Induction of astrocyte glutamine synthetase activity by the Lathyrus toxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (beta-L-ODAP). Glia. vol 7. issue 4. 1993-08-03. PMID:7686536. |
evidence is now presented that low, subgliotoxic concentrations of beta-l-odap may alter the ability of astrocytes to regulate glutamate concentrations in the cns by increasing astrocyte glutamine synthetase activity. |
1993-08-03 |
2023-08-12 |
rat |
| N Westergaard, O M Larsson, B Jensen, A Schousbo. Synthesis and release of GABA in cerebral cortical neurons co-cultured with astrocytes from cerebral cortex or cerebellum. Neurochemistry international. vol 20. issue 4. 1993-07-15. PMID:1339021. |
pure astrocyte cultures did not show any detectable glutamate decarboxylase activity. |
1993-07-15 |
2023-08-11 |
Not clear |