| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Waniewsk. Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures. Journal of neurochemistry. vol 58. issue 1. 1992-01-22. PMID:1345764. |
physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures. |
1992-01-22 |
2023-08-11 |
rat |
| R A Waniewsk. Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures. Journal of neurochemistry. vol 58. issue 1. 1992-01-22. PMID:1345764. |
the effect of ammonia on glutamate accumulation and metabolism was examined in astrocyte cultures prepared from neonatal rat cortices. |
1992-01-22 |
2023-08-11 |
rat |
| R A Waniewsk. Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures. Journal of neurochemistry. vol 58. issue 1. 1992-01-22. PMID:1345764. |
thus, ammonia addition stimulates the conversion of glutamate to glutamine in intact astrocyte cultures. |
1992-01-22 |
2023-08-11 |
rat |
| M Aschner, H K Kimelber. The use of astrocytes in culture as model systems for evaluating neurotoxic-induced-injury. Neurotoxicology. vol 12. issue 3. 1992-01-16. PMID:1684034. |
in cultures of rat cerebral cortex in which astrocyte proliferation is stringently suppressed, glutamate neurotoxicity occurs at low glutamate concentrations similar to those which are normally found in the extracellular space in the hippocampus. |
1992-01-16 |
2023-08-11 |
rat |
| C K Petito, B H Juurlink, L Hert. In vitro models differentiating between direct and indirect effects of ischemia on astrocytes. Experimental neurology. vol 113. issue 3. 1991-11-19. PMID:1915726. |
in addition, they suggest that postischemic astrocyte swelling is related to alterations in extracellular milieu, including accumulation of glutamate and/or alterations in the potassium/sodium ratios with increased potassium and decreased sodium. |
1991-11-19 |
2023-08-11 |
mouse |
| C E Virgin, T P Ha, D R Packan, G C Tombaugh, S H Yang, H C Horner, R M Sapolsk. Glucocorticoids inhibit glucose transport and glutamate uptake in hippocampal astrocytes: implications for glucocorticoid neurotoxicity. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1680166. |
(3) similar gc treatment caused a decrease in astrocyte survival during hypoglycemia and a decrease in the affinity of glutamate uptake. |
1991-10-21 |
2023-08-11 |
Not clear |
| B Flott, W Seifer. Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain. Glia. vol 4. issue 3. 1991-10-18. PMID:1716608. |
characterization of glutamate uptake systems in astrocyte primary cultures from rat brain. |
1991-10-18 |
2023-08-11 |
rat |
| J Albrecht, M Simmons, G R Dutton, M D Norenber. Aluminum chloride stimulates the release of endogenous glutamate, taurine and adenosine from cultured rat cortical astrocytes. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679221. |
primary astrocyte cultures derived from neonatal rat cerebral cortex were treated for 5 min with 0.5 mm or 5.0 mm alcl3, and the incubation medium was analyzed by hplc for the content of released glutamate (glu), taurine (tau), serine (ser) and the nucleoside adenosine (ade). |
1991-09-30 |
2023-08-11 |
rat |
| A M Jensen, S Y Chi. Differential intracellular calcium responses to glutamate in type 1 and type 2 cultured brain astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 6. 1991-07-15. PMID:1675265. |
glutamate (30-500 microm) induced two markedly different [ca2+]i responses in the two astrocyte types: the response in type 1 astrocytes consisted of an initial fast transient followed by varying degrees of oscillations, whereas the predominant response in type 2 astrocytes was a slow rise in [ca2+]i to a more or less sustained and nonoscillatory level. |
1991-07-15 |
2023-08-11 |
rat |
| A M Jensen, S Y Chi. Differential intracellular calcium responses to glutamate in type 1 and type 2 cultured brain astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 6. 1991-07-15. PMID:1675265. |
the results are discussed in terms of the relative distribution of two classes of glutamate receptors on these two astrocyte types: one, the ionotropic class, is linked directly to an ion channel, and the other, the metabotropic class, induces internal mobilization of ca2+ via inositol phospholipid hydrolysis. |
1991-07-15 |
2023-08-11 |
rat |
| M Aschner, N B Eberle, K Miller, H K Kimelber. Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling. Brain research. vol 530. issue 2. 1991-02-11. PMID:2265356. |
interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling. |
1991-02-11 |
2023-08-11 |
rat |
| K M Mearow, J F Mill, E Frees. Neuron-glial interactions involved in the regulation of glutamine synthetase. Glia. vol 3. issue 5. 1990-12-06. PMID:1977701. |
the addition of 100 microm glutamate to the culture medium resulted in an increase in gs mrna in the astrocyte cultures similar to that observed in the cocultures, where the addition of glutamate did not further increase gs mrna levels. |
1990-12-06 |
2023-08-11 |
rat |
| H K Kimelberg, S K Goderie, S Higman, S Pang, R A Waniewsk. Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 5. 1990-06-06. PMID:1970603. |
swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. |
1990-06-06 |
2023-08-11 |
Not clear |
| R A Swanson, A C Yu, P H Chan, F R Shar. Glutamate increases glycogen content and reduces glucose utilization in primary astrocyte culture. Journal of neurochemistry. vol 54. issue 2. 1990-02-27. PMID:1967630. |
glutamate increases glycogen content and reduces glucose utilization in primary astrocyte culture. |
1990-02-27 |
2023-08-11 |
Not clear |
| L Hertz, L Peng, E Hertz, B H Juurlink, P H Y. Development of monoamine oxidase activity and monoamine effects on glutamate release in cerebellar neurons and astrocytes. Neurochemical research. vol 14. issue 10. 1990-02-21. PMID:2575232. |
in 8- and 12-day-old granule cell cultures and in 8- and 18-day old astrocyte cultures there was a pronounced glutamate release during superfusion with 50 mm k+. |
1990-02-21 |
2023-08-11 |
mouse |
| H K Kimelberg, J W Rose, K D Barron, R A Waniewski, E J Crago. Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells. Molecular and chemical neuropathology. vol 11. issue 1. 1989-10-26. PMID:2570584. |
a novel anion exchange inhibitor, l-644,711, inhibits swelling and increased ion uptake caused by glutamate in rat and cat brain slices, as well as inhibiting [3h]glutamate uptake in primary rat astrocyte cultures. |
1989-10-26 |
2023-08-11 |
rat |
| P A Rosenberg, E Aizenma. Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neuroscience letters. vol 103. issue 2. 1989-10-12. PMID:2570387. |
in cultures of rat cerebral cortex in which astrocyte proliferation was stringently suppressed, glutamate neurotoxicity occurred at glutamate concentrations similar to those which are normally found in the extracellular space in the hippocampus. |
1989-10-12 |
2023-08-11 |
rat |
| P A Rosenberg, E Aizenma. Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neuroscience letters. vol 103. issue 2. 1989-10-12. PMID:2570387. |
this suggests that the sensitivity of central neurons to glutamate toxicity may be dependent upon astrocyte function. |
1989-10-12 |
2023-08-11 |
rat |
| D Cambier, B Pessa. Spontaneous glutamate release by a "fibrous"-like cerebellar astroglial cell clone. Journal of neurochemistry. vol 53. issue 2. 1989-08-25. PMID:2568403. |
spontaneous glutamate release by a "fibrous"-like cerebellar astroglial cell clone. |
1989-08-25 |
2023-08-11 |
Not clear |
| D Cambier, B Pessa. Spontaneous glutamate release by a "fibrous"-like cerebellar astroglial cell clone. Journal of neurochemistry. vol 53. issue 2. 1989-08-25. PMID:2568403. |
to investigate the role of astrocytes in the metabolism of glutamate, the neurotransmitter of the granule cells of the cerebellar cortex, we have analyzed various parameters related to the synthesis of glutamate in astroglial cell clones that may be the in vitro counterparts of the cerebellar astrocytes. |
1989-08-25 |
2023-08-11 |
Not clear |