| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao Zhang, Zhao Yan, Asif Maknojia, Manuel A Riquelme, Sumin Gu, Grant Booher, David J Wallace, Viktor Bartanusz, Akshay Goswami, Wei Xiong, Ningyan Zhang, Michael J Mader, Zhiqiang An, Naomi L Sayre, Jean X Jian. Inhibition of astrocyte hemichannel improves recovery from spinal cord injury. JCI insight. vol 6. issue 5. 2021-08-20. PMID:33682795. |
inhibition of astrocyte hemichannel improves recovery from spinal cord injury. |
2021-08-20 |
2023-08-13 |
mouse |
| Jessica L Williams, Sindhu Manivasagam, Brandon C Smith, Julia Sim, Lauren L Vollmer, Brian P Daniels, John H Russell, Robyn S Klei. Astrocyte-T cell crosstalk regulates region-specific neuroinflammation. Glia. vol 68. issue 7. 2021-08-18. PMID:31961459. |
using in vivo models of spinal cord versus brain stem trafficking of myelin-specific t cells and astrocyte-specific deletion strategies, we confirmed that th1 and th17 cytokines differentially regulate astrocyte expression of vcam-1 and cxcr7 in these locations. |
2021-08-18 |
2023-08-13 |
human |
| Francesco Pisani, Laura Simone, Maria Grazia Mola, Manuela De Bellis, Antonio Frigeri, Grazia Paola Nicchia, Maria Svelt. Regulation of aquaporin-4 expression in the central nervous system investigated using M23-AQP4 null mouse. Glia. vol 69. issue 9. 2021-08-18. PMID:34038017. |
m1-aqp4 transcription, splicing and m1-aqp4 protein degradation were found to be unaffected in m23-null spinal cord and in m23-null astrocyte primary culture. |
2021-08-18 |
2023-08-13 |
mouse |
| Jiyun Peng, Min-Hee Yi, Heejin Jeong, Przemyslaw Peter McEwan, Jiaying Zheng, Gongxiong Wu, Shashank Ganatra, Yi Ren, Jason R Richardson, Seog Bae Oh, Long-Jun W. The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34183051. |
in addition, microglial production of reactive oxygen species (ros) and subsequent astrocyte activation in the spinal cord was reduced in hv1 ko mice after snt. |
2021-08-12 |
2023-08-13 |
mouse |
| Jingyi Mi, Yang Yang, Hao Yao, Zhirong Huan, Ce Xu, Zhiheng Ren, Wenfu Li, Ying Tang, Rao Fu, Xin G. Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury. Journal of neuroinflammation. vol 18. issue 1. 2021-08-10. PMID:34362408. |
inhibition of heat shock protein family a member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte nf-κb/nlrp3 inflammasome pathway : hspa8 inhibition protects spinal ischemia-reperfusion injury. |
2021-08-10 |
2023-08-13 |
Not clear |
| Jingyi Mi, Yang Yang, Hao Yao, Zhirong Huan, Ce Xu, Zhiheng Ren, Wenfu Li, Ying Tang, Rao Fu, Xin G. Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury. Journal of neuroinflammation. vol 18. issue 1. 2021-08-10. PMID:34362408. |
astrocyte over-activation and extensive neuron loss are the main characteristic pathological features of spinal cord ischemia-reperfusion injury (scii). |
2021-08-10 |
2023-08-13 |
Not clear |
| Francisco Javier Rodriguez-Jimenez, Angel Vilches, Maria Amparo Perez-Arago, Eleonora Clemente, Raquel Roman, Juliette Leal, Ana Artero Castro, Santos Fustero, Victoria Moreno-Manzano, Pavla Jendelova, Miodrag Stojkovic, Slaven Erce. Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 1. 2021-07-30. PMID:33000422. |
the inhibition of glycogen synthase kinase-3 (gsk-3) can induce neurogenesis, and the associated activation of wnt/β-catenin signaling via gsk-3 inhibition may represent a means to promote motor function recovery following spinal cord injury (sci) via increased astrocyte migration, reduced astrocyte apoptosis, and enhanced axonal growth. |
2021-07-30 |
2023-08-13 |
mouse |
| Martin Marsala, Kota Kamizato, Takahiro Tadokoro, Michael Navarro, Stefan Juhas, Jana Juhasova, Silvia Marsala, Hana Studenovska, Vladimir Proks, Tom Hazel, Karl Johe, Manabu Kakinohana, Shawn Driscoll, Thomas Glenn, Samuel Pfaff, Joseph Ciacc. Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats. Stem cells translational medicine. vol 9. issue 2. 2021-07-21. PMID:31800978. |
immunofluorescence staining and mrna sequencing analysis demonstrated a near-complete occupation of the spinal cord by injected cells, in which transplanted human nscs (hnscs) preferentially acquired glial phenotypes, expressing oligodendrocyte (olig2, apc) or astrocyte (gfap) markers. |
2021-07-21 |
2023-08-13 |
human |
| Ha Neui Kim, Monica R Langley, Whitney L Simon, Hyesook Yoon, Laurel Kleppe, Ian R Lanza, Nathan K LeBrasseur, Aleksey Matveyenko, Isobel A Scarisbric. A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism. Neurobiology of disease. vol 141. 2021-07-14. PMID:32376475. |
a western diet impairs cns energy homeostasis and recovery after spinal cord injury: link to astrocyte metabolism. |
2021-07-14 |
2023-08-13 |
mouse |
| Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Dallas Boodhoo, Armugam Mekala, Cornelia Cudrici, Tudor C Badea, Dafin F Muresanu, Violeta Rus, Horea Ru. RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis. Frontiers in immunology. vol 11. 2021-06-23. PMID:33569054. |
we have previously shown that lack of response gene to complement 32 (rgc-32) alters astrocyte morphology in the spinal cord at the peak of experimental autoimmune encephalomyelitis (eae), suggesting a role for rgc-32 in astrocyte differentiation. |
2021-06-23 |
2023-08-13 |
mouse |
| Hongyan Zhang, Jingjing Liu, Chengming Ling, Xin Chen, Jiangkai Lin, Hua Feng, Weihua Ch. High mobility group box 1 promotes the differentiation of spinal ependymal cells into astrocytes rather than neurons. Neuroreport. vol 32. issue 5. 2021-06-21. PMID:33661806. |
ependymal cells extracted and cultured from the spinal cord of mice were separately treated with astrocyte culture medium (acm), il-1β, acm (il-1β) and the hmgb1 protein, and the proliferation and differentiation of ependymal cells were detected. |
2021-06-21 |
2023-08-13 |
mouse |
| Hong-Jun Zou, Shi-Wu Guo, Lin Zhu, Xu Xu, Jin-Bo Li. Methylprednisolone Induces Neuro-Protective Effects via the Inhibition of A1 Astrocyte Activation in Traumatic Spinal Cord Injury Mouse Models. Frontiers in neuroscience. vol 15. 2021-06-19. PMID:34135725. |
methylprednisolone induces neuro-protective effects via the inhibition of a1 astrocyte activation in traumatic spinal cord injury mouse models. |
2021-06-19 |
2023-08-13 |
mouse |
| Thierry Paquette, Mathieu Piché, Hugues Leblon. Contribution of astrocytes to neurovascular coupling in the spinal cord of the rat. The journal of physiological sciences : JPS. vol 71. issue 1. 2021-05-31. PMID:34049480. |
these results support the role of astrocytes in spinal nvc and have implications for spinal cord imaging with fmri for conditions in which astrocyte metabolism may be altered. |
2021-05-31 |
2023-08-13 |
rat |
| Samira Eghbaliferiz, Faegheh Farhadi, George E Barreto, Muhammed Majeed, Amirhossein Sahebka. Effects of curcumin on neurological diseases: focus on astrocytes. Pharmacological reports : PR. vol 72. issue 4. 2021-05-28. PMID:32458309. |
in light of this, our current review aims to discuss the role of astrocytes as essential players in neurodegenerative diseases and suggest that curcumin is capable of direct inhibition of astrocyte activity with a particular focus on its effects in alexander disease, alzheimer's disease, ischemia stroke, spinal cord injury, multiple sclerosis, and parkinson's disease. |
2021-05-28 |
2023-08-13 |
Not clear |
| Masoumeh Zarei-Kheirabadi, Alexander R Vaccaro, Vafa Rahimi-Movaghar, Sahar Kiani, Hossein Baharvan. An Overview of Extrinsic and Intrinsic Mechanisms Involved in Astrocyte Development in the Central Nervous System. Stem cells and development. vol 29. issue 5. 2021-05-19. PMID:31847709. |
in astrocyte patterning, va1-va3 domains create the astrocyte subtypes by differential expression of slit1 and reelin in the spinal cord. |
2021-05-19 |
2023-08-13 |
Not clear |
| Manoj K Gottipati, Anthony R D'Amato, Alexis M Ziemba, Phillip G Popovich, Ryan J Gilber. TGFβ3 is neuroprotective and alleviates the neurotoxic response induced by aligned poly-l-lactic acid fibers on naïve and activated primary astrocytes. Acta biomaterialia. vol 117. 2021-05-14. PMID:33035696. |
to assess astrocyte reactivity in response to aligned poly-l-lactic acid microfibers, naïve spinal cord astrocytes or spinal cord astrocytes primed towards the neurotoxic phenotype (a1) were cultured on fibrous scaffolds. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yupeng Wang, Haoxiao Chang, Xinghu Zhang, Linlin Yi. Efficacy of rituximab in the treatment of neuromyelitis optica spectrum disorders: An update systematic review and meta -analysis. Multiple sclerosis and related disorders. vol 50. 2021-05-14. PMID:33609924. |
neuromyelitis optica spectrum disorders (nmosd) is an autoimmune astrocyte disease that mainly affects the optic nerve and spinal cord resulting in blindness or paralysis. |
2021-05-14 |
2023-08-13 |
Not clear |
| Áurea Gabriela Rodrigues Mendes, Gabriel Gomes Vilar de Sousa, Martha de Souza França, Carlos Alberto Marques de Carvalho, Evander de Jesus Oliveira Batista, Adelaide da Conceição Fonseca Passos, Karen Renata Herculano Matos Oliveira, Anderson Manoel Herculano, Suellen Alessandra Soares de Morae. Astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats. Heliyon. vol 7. issue 4. 2021-05-14. PMID:33981899. |
astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats. |
2021-05-14 |
2023-08-13 |
rat |
| Áurea Gabriela Rodrigues Mendes, Gabriel Gomes Vilar de Sousa, Martha de Souza França, Carlos Alberto Marques de Carvalho, Evander de Jesus Oliveira Batista, Adelaide da Conceição Fonseca Passos, Karen Renata Herculano Matos Oliveira, Anderson Manoel Herculano, Suellen Alessandra Soares de Morae. Astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats. Heliyon. vol 7. issue 4. 2021-05-14. PMID:33981899. |
astrocyte reactivity in the spinal cord may occur after peripheral neural damage. |
2021-05-14 |
2023-08-13 |
rat |
| Áurea Gabriela Rodrigues Mendes, Gabriel Gomes Vilar de Sousa, Martha de Souza França, Carlos Alberto Marques de Carvalho, Evander de Jesus Oliveira Batista, Adelaide da Conceição Fonseca Passos, Karen Renata Herculano Matos Oliveira, Anderson Manoel Herculano, Suellen Alessandra Soares de Morae. Astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats. Heliyon. vol 7. issue 4. 2021-05-14. PMID:33981899. |
astrocyte reactivity was observed in the l5 segment of the spinal cord with predominance in the white matter regions and decrease in the mechanical threshold of the ipsilateral paw only in rup2. |
2021-05-14 |
2023-08-13 |
rat |