| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yongyuan Zhang, Xiaohui Wang, Chao Jiang, Zhe Chen, Shuangyang Ni, Hong Fan, Zhiyuan Wang, Fang Tian, Jing An, Hao Yang, Dingjun Ha. Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway. Neurochemical research. 2022-09-14. PMID:36103106. |
rho kinase inhibitor y27632 improves recovery after spinal cord injury by shifting astrocyte phenotype and morphology via the rock/nf-κb/c3 pathway. |
2022-09-14 |
2023-08-14 |
rat |
| Xiaolong Zheng, Wei Wan. Astrocyte transplantation for repairing the injured spinal cord: a mini-review. Journal of biomedical research. 2022-09-03. PMID:36056564. |
astrocyte transplantation for repairing the injured spinal cord: a mini-review. |
2022-09-03 |
2023-08-14 |
human |
| Yuan-Yuan Fu, Jian-Ke Cen, Hao-Lin Song, Si-Yuan Song, Zhi-Jun Zhang, Huan-Jun L. Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-MAPK axis. Molecular pain. 2022-08-30. PMID:36039405. |
rh2 also inhibited microglia and astrocyte activation in the spinal cord of a murine sni model. |
2022-08-30 |
2023-08-14 |
Not clear |
| Dong Li, Tiantian Sun, Ling Tao, Wangquan Ji, Peiyu Zhu, Ruonan Liang, Yu Zhang, Shuaiyin Chen, Haiyan Yang, Yuefei Jin, Guangcai Dua. A Mouse-adapted CVA6 Strain Exhibits Neurotropism and Triggers Systemic Manifestations in a Novel Murine Model. Emerging microbes & infections. 2022-08-29. PMID:36036059. |
inoculation, pathological examination showed brain and spinal cord damage caused by the virus infection with neuronal reduction, apoptosis, astrocyte activation, and recruitment of neutrophils and monocytes. |
2022-08-29 |
2023-08-14 |
mouse |
| Longkuo Xia, Jianhuan Qi, Mingming Tang, Jing Liu, Da Zhang, Yanbing Zhu, Baoyang H. Continual Deletion of Spinal Microglia Reforms Astrocyte Scar Favoring Axonal Regeneration. Frontiers in pharmacology. vol 13. 2022-07-14. PMID:35833026. |
astrocyte scar formation after spinal cord injury (sci) efficiently limits the accurate damage but physically restricts the following axon regeneration. |
2022-07-14 |
2023-08-14 |
mouse |
| Longkuo Xia, Jianhuan Qi, Mingming Tang, Jing Liu, Da Zhang, Yanbing Zhu, Baoyang H. Continual Deletion of Spinal Microglia Reforms Astrocyte Scar Favoring Axonal Regeneration. Frontiers in pharmacology. vol 13. 2022-07-14. PMID:35833026. |
here, utilizing an improved drug administration approach, we show that in a mouse model of spinal cord injury, continual deletion of microglia, especially upon scar formation, by pexidartinib decreases the amount of microglia-derived collagen i and reforms the astrocyte scar. |
2022-07-14 |
2023-08-14 |
mouse |
| Alessia Niceforo, Tara Fortino, Yashvi Shah, Lyandysha V Zholudeva, Liang Qiang, Michael A Lan. Astrocyte-to-neuron reprogramming for spinal cord repair. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555610. |
primary astrocyte cultures were generated from postnatal days 2-3 (p2-3) rat cortex and spinal cord, and then were activated with tgfβ (transforming growth factor beta) one day prior to viral transduction. |
2022-05-13 |
2023-08-13 |
rat |
| Dexiang Ban, Peng Yu, Zhenyang Xiang, Yang Li. TNF-like weak inducer of apoptosis / nuclear factor κB axis feedback loop promotes spinal cord injury by inducing astrocyte activation. Bioengineered. vol 13. issue 5. 2022-05-04. PMID:35506163. |
tnf-like weak inducer of apoptosis / nuclear factor κb axis feedback loop promotes spinal cord injury by inducing astrocyte activation. |
2022-05-04 |
2023-08-13 |
mouse |
| Hiroaki Okuda, Tatsuya Ishikawa, Kiyomi Hori, Nichakarn Kwankaew, Noriyuki Ozak. Hedgehog signaling plays a crucial role in hyperalgesia associated with neuropathic pain in mice. Journal of neurochemistry. 2022-04-19. PMID:35437761. |
contrastingly, astrocyte activation in the spinal cord did not differ between the groups. |
2022-04-19 |
2023-08-13 |
mouse |
| A Lee, S Klinkradt, P A McCombe, D V Po. Cloning of a new form of EAAT2/GLT-1 from human and rodent brains. Neuroscience letters. 2022-04-19. PMID:35439550. |
rt-pcr amplification using glt-1d specific primers confirmed expression of message in all brain regions examined (forebrain, midbrain, hindbrain and cerebellum) as well as spinal cord, astrocyte cultures, retina and peripheral tissues (liver, testis, small intestine and lung). |
2022-04-19 |
2023-08-13 |
human |
| Ciro De Luca, Assunta Virtuoso, Sohaib Ali Korai, Raffaella Cirillo, Francesca Gargano, Michele Papa, Giovanni Cirill. Altered Spinal Homeostasis and Maladaptive Plasticity in GFAP Null Mice Following Peripheral Nerve Injury. Cells. vol 11. issue 7. 2022-04-12. PMID:35406788. |
glial acidic fibrillary protein (gfap), a major protein constituent of astrocyte intermediate filaments (ifs), is the hallmark of the reactive astrocytes, has pleiotropic functions and is significantly upregulated in the spinal cord after nerve injury. |
2022-04-12 |
2023-08-13 |
mouse |
| Xinwang Ying, Xiaolan Yu, Jintao Zhu, Xuqing Li, Yujun Zheng, Qingfeng Xie, Qiaoyun Wu, Shengcun Li, Jingjing Yue, Ye Zhou, Kecheng Zhou, Wenzhan Tu, Songhe Jian. Water Treadmill Training Ameliorates Neurite Outgrowth Inhibition Associated with NGR/RhoA/ROCK by Inhibiting Astrocyte Activation following Spinal Cord Injury. Oxidative medicine and cellular longevity. vol 2022. 2022-04-07. PMID:35387259. |
water treadmill training ameliorates neurite outgrowth inhibition associated with ngr/rhoa/rock by inhibiting astrocyte activation following spinal cord injury. |
2022-04-07 |
2023-08-13 |
rat |
| Zhi-Jun Weng, Shi-Xiu Hu, Fang Zhang, Zhi-Ying Zhang, Yun Zhou, Min Zhao, Yan Huang, Yu-Hu Xin, Huan-Gan Wu, Hui-Rong Li. Spinal cord astrocyte P2X7Rs mediate the inhibitory effect of electroacupuncture on visceral hypersensitivity of rat with irritable bowel syndrome. Purinergic signalling. 2022-04-07. PMID:35389158. |
spinal cord astrocyte p2x7rs mediate the inhibitory effect of electroacupuncture on visceral hypersensitivity of rat with irritable bowel syndrome. |
2022-04-07 |
2023-08-13 |
rat |
| Lorenzo Di Cesare Mannelli, Laura Micheli, Chiara Cervetto, Alessandra Toti, Elena Lucarini, Carmen Parisio, Manuela Marcoli, Carla Ghelardin. Neuronal alarmin IL-1α evokes astrocyte-mediated protective signals: Effectiveness in chemotherapy-induced neuropathic pain. Neurobiology of disease. 2022-04-03. PMID:35367629. |
this protective effect paralleled with an increased number of gfap-positive cells in the spinal cord, suggesting the ability of il-1α to evoke a positive, conservative astrocyte phenotype. |
2022-04-03 |
2023-08-13 |
rat |
| Can Hao, Bingjie Ma, Nan Gao, Tian Jin, Xiaoming Li. Translocator Protein (TSPO) Alleviates Neuropathic Pain by Activating Spinal Autophagy and Nuclear SIRT1/PGC-1α Signaling in a Rat L5 SNL Model. Journal of pain research. vol 15. 2022-03-31. PMID:35356265. |
recent studies showed promotion of astrocyte autophagy in the spinal cord would provide analgesic effects. |
2022-03-31 |
2023-08-13 |
rat |
| Yeyang Wang, Wenjun Li, Mingsen Wang, Chuangxin Lin, Guitao Li, Xiaozhong Zhou, Junnan Luo, Dadi Ji. Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. Journal of cellular biochemistry. 2022-03-23. PMID:35319108. |
quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. |
2022-03-23 |
2023-08-13 |
rat |
| Chen Li, Zhourui Wu, Liqiang Zhou, Jingliang Shao, Xiao Hu, Wei Xu, Yilong Ren, Xingfei Zhu, Weihong Ge, Kunshan Zhang, Jiping Liu, Runzhi Huang, Jing Yu, Dandan Luo, Xuejiao Yang, Wenmin Zhu, Rongrong Zhu, Changhong Zheng, Yi Eve Sun, Liming Chen. Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury. Signal transduction and targeted therapy. vol 7. issue 1. 2022-03-02. PMID:35232960. |
we discovered novel microglia and astrocyte subtypes in the uninjured spinal cord, and their dynamic conversions into additional stage-specific subtypes/states. |
2022-03-02 |
2023-08-13 |
mouse |
| R Vivian Allahyari, Nicolette M Heinsinger, Daniel Hwang, David A Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J Thomas, Theodore J Price, Abdolmohamad Rostami, Angelo C Lepor. Response of Astrocyte Subpopulations Following Spinal Cord Injury. Cells. vol 11. issue 4. 2022-02-25. PMID:35203371. |
response of astrocyte subpopulations following spinal cord injury. |
2022-02-25 |
2023-08-13 |
mouse |
| R Vivian Allahyari, Nicolette M Heinsinger, Daniel Hwang, David A Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J Thomas, Theodore J Price, Abdolmohamad Rostami, Angelo C Lepor. Response of Astrocyte Subpopulations Following Spinal Cord Injury. Cells. vol 11. issue 4. 2022-02-25. PMID:35203371. |
interestingly, one subpopulation (population c) was shown to possess significantly enhanced synaptogenic properties in vitro, as compared with other astrocyte subpopulations of adult cortex and spinal cord. |
2022-02-25 |
2023-08-13 |
mouse |
| R Vivian Allahyari, Nicolette M Heinsinger, Daniel Hwang, David A Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J Thomas, Theodore J Price, Abdolmohamad Rostami, Angelo C Lepor. Response of Astrocyte Subpopulations Following Spinal Cord Injury. Cells. vol 11. issue 4. 2022-02-25. PMID:35203371. |
using flow cytometry and rnascope in situ hybridization, we found that astrocyte subpopulation distribution in the spinal cord did not change to a selectively synaptogenic phenotype following mouse cervical hemisection-type sci. |
2022-02-25 |
2023-08-13 |
mouse |